9 research outputs found
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Current resources updated: 04/08/202
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
- Alameen Maram
- Alamlih Laith
- Alaqoubi Retaj
- Alarabi Rehab
- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
- Albarki Aisha
- Albashaireh Alaa
- Albatni Safa Sasi
- Albayadi Eslam
- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
- Alshareea Entisar
- Alshawadfy Abdelrhman
- Alshawesh Aisha
- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
- Alzyoud Osama
- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
- Aminu Muhammad Baffah
- Ammar Ahmed Siddique
- Amro Dana
- Ananthapadmanabhan Shravankrishna
- Anderson Paul
- Andrew Paul Chimezie
- Andriani Adelaide
- Anestiadou Elissavet
- Angelis Fragkiskos
- Angeslis Fragkiskos
- Aqeel Syed Talha Bin
- Aral Canan
- Arebi Jaber
- Arnaoutoglou Eleni
- Arslangilay Mert
- Arvanitaki Alexandra
- Asadyari-Lupo Shadie
- Ashar Nur Ayuni Khirul
- Ashour Amira
- Ashraf Hamza
- Ashur Abir Ben
- Asjad Imran
- Askar Aamal
- Askin Abdullah Emre
- Aslam Muhammad Nadeem
- Aslan Merve
- Aslangilay Mert
- Astal Mohammed
- Asudo Felicia
- Atadag Yildiz Buyukdereli
- Atef Dina
- Athamneh Tayseer
- Athanasiadis Apostolos
- Ather M Hammad
- Atherton Kristy
- Atia Ahmed
- Atici Semra Demirli
- Atilhan Ridvan
- Atim Terkaa
- Atiq Tabish
- Atta Raneem
- Attia Mohamed
- Attiya Omar
- Awad Hasan
- Awadallah Safaa
- Awoyinka Babatunde
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- Aydin Cemil
- Aydoğdu Erhan Onur
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- Fearnley-Fitzgerald Chekodi
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- Feierdaiweisi Xireaili
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- Figgitt Ethan
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- Wright Deborah
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- Wu Hongyi
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- Xie Maria
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- Xu William
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- Yaghmour Jamal
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- Yildirim Yasemin
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- Yilmaz Hakan
- Yin Chonghao
- Ying Geoffrey
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- Yong Nathania
- Yoon Si Woo
- You Ha Seong
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- Yousri Mohamed
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- Youssef Arkan
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- Yue Tiffany
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- Yusuf Stephen
- Yuzgec Ayse Nilufer
- Zachomitros Fotios
- Zaed Moahmed
- Zafar Fatima
- Zaghloul Ahmed
- Zaheer Adil
- Zaidi Faseeh
- Zain Ahmad
- Zakaria Ahmed
- Zakaria Andee Dzulkarnaen
- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- Abantanga FA
- Abatli SJ
- Abbas W
- Abbo O
- Abd Elmenam M
- Abd Razak RB
- Abdelbaqi R
- Abdelhady DS
- Abdelhafez MOM
- Abdelhamid SS
- Abdelmaksoud S
- Abdelmoumen R
- Abdelmutalib F
- Abdul-Mumin A
- Abduljawad FM
- Abdullah F
- Abdulraheem N
- Abdulrahman A
- Abdulsalam MA
- Abdunomonovich DA
- Abib SDCV
- Aboelela A
- Abouheba M
- Abrahamsson K
- Abu Ajwa AE
- Abu Al-saleem HSH
- Abu Alamrain AA
- Abu Bakar AH
- Abu Farha MS
- Abu Jamie N
- Abu Jamie YMK
- Abu Jayyab M
- Abu Mayaleh A
- Abu Shiha E
- Abu Za'nouneh FJ
- Abu-Nejmah F
- Abuajaila A
- Abuattaya AA
- Abubakar AM
- Abueideh A
- Abuhayyeh HA
- Abuhlega MA
- Abukhalaf S
- Abumunshar AA
- Acuna G
- Adams S
- Adamu S
- Adanan MFSBM
- Adawi I
- Adawi S
- Adawy A
- Ade-Ajayi N
- Adegboyega R
- Ademuyiwa A
- Adesanya O
- Adhiwidjaja CF
- Adofo-Ansong N
- Agboola TH
- Agelebe E
- Aguiar AA
- Aguilar FA
- Aguirre-Lopez P
- Agulham MA
- Ahmad H
- Ahmad ZAH
- Ahmed H
- Ahmed MA
- Ajai OT
- Ajao EA
- Ajiboye OS
- Ajrami Y
- Akan ME
- Akhbari M
- Akhter N
- Akova F
- Al Dammagh NM
- Al Hussein S
- Al Massry NA
- Al Quran TM
- Al-Attar HM
- Al-Halbouni L
- Al-Mamun A
- Al-Mayoof AF
- Al-Momani HM
- Al-Mouakeh A
- Al-Rayyes M
- Al-Salhi AA
- Al-Shwaikh SH
- Al-Slaibi I
- Al-Taher RN
- Al-Taher RN
- Al-Tammam H
- Alakaloko F
- Alattas K
- Alberto C
- Albozidi A
- Alcantara E
- Aldirawi MAM
- Alebbini MM
- Alfoghi M
- Algabri HNO
- Alglaib MM
- Alhamid A
- Alhamid A
- Alhassan P
- Ali H
- Ali KO
- Ali L
- Ali M
- Alijla S
- Alijla SS
- Aliwisat AH
- Aljaboo H
- Aljadidi WOFS
- Aljarad Z
- Alkali YS
- Alkareem RMA
- Almada SA
- Almadhoun W
- Almasri M
- Almeida G
- Almengar I
- Almohamady H
- Almosaibli M
- Almusleh TFH
- Alnaeri A
- Alnahhal K
- Alonso V
- Alosta HM
- Alqarajeh F
- Alqor MOI
- Alsaadi NN
- Alsaggaf A
- Alsaied A
- Alser M
- Alser OH
- Alshaikhkhalil HAA
- Alshehri A
- Altamirano PR
- Altaweel A
- Altin M
- Altokhais T
- Altomi M
- Alturki F
- Alva LRC
- Alvarez JR
- Alwadia SMS
- Alwaggaa NA
- Alzamari AAM
- Alzeer AMS
- Alzerei ST
- Alzraikat SH
- Alzubair A
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- Amad M
- Amado F
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- Amah CC
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- Arabiat E
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- Aucatoma FC
- Augusto MLDS
- Avila DC
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- Aziz DAA
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- Badr H
- Baertschiger R
- Bagbio D
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- Bai YZ
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- Baker W
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- Bamanga A
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- Barbosa PR
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- Baron JDJC
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- Bin Amjad M
- bin Bujarimin AS
- bin Hassan MR
- Bin Othman MY
- bin Zahari Z
- bin Zarwawi AZ
- Bischoff C
- Blain OE
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- Borbonet D
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- Bucaram E
- Burgos CM
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- Cai D
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- Carbajal LF
- Carloni ICS
- Carrasco AL
- Carrasco-Ortega C
- Carrillo I
- Casado FT
- Caseb P
- Casquero V
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- Castillo MN
- Cavaiuolo S
- Cekic B
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- Centen SV
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- Chipana CLA
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- Cino EL
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- Correa C
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- Cripovich A
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- Cunningham A
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- Czauderna P
- da Cunha AG
- da Silva EAD
- da Silva JAN
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- Dagilyte R
- Daher AP
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- Dieudonne L
- Dimatatac DM
- Djordjevic I
- do Nascimento SD
- Dogar S
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- dos Santos MSF
- Dosselman LJ
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- Duchesne C
- Duggan E
- Dure C
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- Echegaray MD
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- Ejinkeonye EC
- Ekenze SO
- Ekwunife OH
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- El-Ghazaly M
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- von Bismarck S
- von Delft D
- Vosoughi A
- Wafa T
- Walker G
- Wang D
- Wang J
- Wang J
- Wang P
- Waseem B
- Weeratunga N
- Weiszewsk A
- Wen G
- Wester T
- Wijekoon N
- Wilke A
- Williams I
- Williams O
- Williams R
- Wilson MDF
- Win WSP
- Wishah BDM
- Wishah N
- Wissanji H
- Wolak P
- Wolny A
- Wong J
- Wong M
- Wright NJ
- Wu G
- Wyrzykowski D
- Xie H
- Yacoub MA
- Yaghi B
- Yaghi DH
- Yalcinkaya A
- Yang H-B
- Yanis AH
- Yao Y
- Yapo B
- Yeniay AO
- Yola MM
- Yong F
- Youn JK
- Yousuf H
- Yu M
- Yu R
- Yuen QS
- Yuldashev RZ
- Yunus A
- Zaghlol LY
- Zain M
- Zaman ASK
- Zanellato JB
- Zea-Salazar LE
- Zeinelabdeen A
- Zelada JA
- Zhao X
- Zhu J
- Zhu L
- Zidan M
- Zivanovic D
- Zreeg DAS
- Zurikat RO
- Zvizdic N
- Zvizdic Z
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 24/07/2021
- Field of study
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
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- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
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- Allam Mushal
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- Lako Richard Lino Loro
- Lalemi Mary
- Lambisia Arnold W.
- Lamboni Lallepak
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- Tegally Houriiyah
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- Thiam Aminata Sileymane
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- Umuringa Jeanne d’Arc
- Upton Arlo
- Ushijima Yuri
- Ussher James
- Utpatel Christian
- Uwanibe Jessica N.
- Uwituze Arlene
- van der Eijk Annemiek
- van der Linden Anne
- van der Linden Antje
- van der Werf Sylvie
- Van Rooyen G.
- van Rooyen Gerhard
- van Wyk Stephanie
- van Zyl Gert U.
- Vanaerschot M.
- Vanmechelen Bert
- Vanpeene Maud
- Velavan Thirumalaisamy P.
- Venter Marietjie
- Vernet Marie-Astrid
- Viana R.
- Vickos U.
- Victoir Kathleen
- Vida Ahyong
- Vidal Nicole
- Viegas Sofia
- Vincent Grace
- Vinze Anika
- Voegtly Logan J.
- von Gottberg Anne
- Waberi Zeinab Ali
- Wadi Amira Suliaman
- Wadonda N.
- Wadula J.
- Wagner Philipp
- Wahab Kolawole Wasiu
- Waitumbi John
- Walter Mathias C.
- Wamala Joseph F.
- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
- Wanjohi Dorcas W.
- Wanok Stephen
- Waruhiu C.N.
- Waruhiu Cecilia
- Wasfi Fares
- Watters Chaselynn M.
- Wawina-Bokalanga Tony
- Wayengera Misaki
- Wayoro Oby
- Webby R.
- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- A. Mohammed Kalakwa
- A. Nemer Ayoub
- Abantanga Francis A.
- Abatli Safa' Jamal
- Abbas Wisam
- Abbo Olivier
- Abdelbaqi Reem
- Abdelhady Dina Sobhy
- Abdelhafez Mohammad Omar Mohammad
- Abdelhamid Sultan S.
- Abdelmaksoud Sherif
- Abdelmoumen Roua
- Abdelmutalib Fakereldeen
- Abdul-Mumin Alhassan
- Abduljawad Fatima Mousa
- Abdullah Fizan
- Abdullah Mohd Yusof bin
- Abdulraheem Nurudeen
- Abdulrahman Alaa
- Abdulsalam Moruf Adekunle
- Abdunomonovich Dekhkonboev Avazjon
- Aboelela Ahmed
- Abouheba Mohamed
- Abrahamsson Kate
- Abrunhosa Matias Marcia
- Abu-Nejmah Fawzi
- Abuajaila Abdulsalam
- Abuattaya Adham Ashraf
- Abubakar Auwal M
- Abueideh Ahmad
- Abuhayyeh Husam Aldean
- Abuhlega Ma'aly A.
- Abukhalaf Sadi
- Abumunshar Ali Abdelhay
- Acuna Gaston
- Adams Stephen
- Adamu Sani
- Adanan Mohd Fitri Shukri bin Mohamed
- Adawi Ihda
- Adawi Samer
- Adawy Ahmad
- Ade-Ajayi Niyi
- Adegboyega Rilwan
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adhiwidjaja Cathline Freya
- Adofo-Ansong Nana
- Agboola Titiloye Hannah
- Agelebe Efeturi
- Aguilar Aguilar Faye
- Aguilar Gargurevich Prince Pamela
- Aguirre-Lopez Pastor
- Agulham Miguel Angelo
- Ahmad Hira
- Ahmad Zahidah Adlynee Haji
- Ahmed Hazem
- Ahmed Mahmoud Abdelfattah
- Ajai Olalekan Temitope
- Ajao Emmanuel Akinlabi
- Ajiboye Olalekan S.
- Ajrami Yara
- Ajwa Ahmad Elian Abu
- Akan M. Eren
- Akhbari Melika
- Akhter Nadeem
- Akova Fatih
- Al-Attar Hala M.
- Al-Halbouni Layana
- Al-Mamun Abdullah
- Al-Mayoof Ali Farooq
- Al-Momani Hashem M.
- Al-Mouakeh Ahmad
- Al-Rayyes Maisara
- Al-saleem Hasan Subhi Hasan Abu
- Al-Salhi Ashraf Ayman
- Al-Shwaikh Samar H.
- Al-Slaibi Ibrahim
- Al-Taher Raed Nael
- Al-Taher Raed Nael
- Al-Tammam Hiba
- Alakaloko Felix
- Alamrain Abdulwhhab Ayman Abu
- Alanguia Chipana Cathy Lee
- Alattas Khalid
- Alberto Carlos
- Albozidi Aya
- Alcántara Elvyn
- ALDIRAWI MOHAMMED A. M.
- Alebbini Mohanad Mutasem
- Alfoghi Mabroka
- Algabri Hayder Nadhim Obaid
- Alglaib Mohammed Meftah
- Alhamid Ahmad
- Alhamid Aos
- Alhassan Priscilla
- Ali Hassan
- Ali Karim Osamy
- Ali Liza
- Ali Mansour
- Alijla Sharif
- Alijla Sharif S.
- Aliwisat Ahmad Hasan
- Aljaboo Hajir
- Aljadidi Wesal Omar F. Saied
- Aljarad Ziad
- Alkareem Raghad mohammad abdu
- Almada Suad Ahmed
- Almadhoun Walaa
- Almasri Murad
- Almeida Aguiar Arthur
- Almeida Giovana
- Almengar Inas
- Almohamady Hisham
- Almosaibli Mohammad
- Almusleh Tasneem Fathi Hasan
- Alnaeri Ali
- Alnahhal Khaled
- Alonso Verónica
- Alosta Hasan Mustafa
- Alqarajeh Firas
- Alqor Mohammad Omar Ibrahim
- Alsaadi Nijmeh Nasser
- Alsaggaf Ameen
- Alsaied Amer
- Alser Mohammed
- Alser Osaid H.
- Alshaikhkhalil Haya Abdulnasser Ali
- Alshehri Abdullah
- Altaweel Ahmed
- Altın Merve
- Altokhais Tariq
- Altomi Mohamed
- Alturki Fahad
- Alvarado Zelada Jackelyne
- Alves Dutra da Silva Érika
- Alwadia Soha Marwan Salem
- Alwaggaa Nouriyah Ali
- Alzamari Ainaa Ata Mohammad
- Alzate Gallego Edgar
- Alzeer Asmahan Mohammad Suliman
- Alzerei Sulaiman T.
- Alzraikat Sayel H.
- Alzubair Afnan
- Alzughayyar Tareq Z.
- Amad Mohamed
- Amado Fernando
- Amaechi Chukwubinyelum
- Amah Christopher Chim
- Amarin Justin Z.
- Amarin Marzouq
- Ambriz-González Gabriela
- Ameh Emmanuel
- Amjad Muhammad Bin
- Amoabin Afua Amoabin
- Anatole Nzanzu
- Anatole Nzanzu Kipata
- Anaya Dominguez Marlene
- Anaya Firas
- Andrade Jerhy
- Andreussi Lorna
- Anicama Elias Rocio
- Annajjar Mohammad hasan
- Anntinea Jessmine
- Antunes Amanda
- Antunez-Mora Alexandra
- Anyomih Theophilus Teddy Kojo
- Anzelewicz Stefan
- Apaza Leon Jose Luis
- Appeadu-Mensah William
- Arabiat Esraa
- Arafa Mohamed Ahmed
- Arafat Hasan
- Aragão Liliana
- Arancibia Gutiérrez Elsa
- Aranda Sánchez Cristian Irela
- Arar Ahmad Samih
- Arauco Jenny
- Arbab Hana
- Arboleda Jenny
- Aremo Anuoluwapo
- Arnadóttir Helena
- Arnaud Alexis P
- Arnold Marion
- Arnoletto Lucia Beatriz
- Arrmali Saddam
- Arrmalli Lina Ali
- Arshad Muhammad
- Arthur Felicity
- Arul Suren
- Ashour Dina Ayman
- Ashour Yara shareef
- Aslan Yakup
- Aspirot Ann
- Assi Ahmadfateh
- Assi Muath Abdelrahem Fuad
- Astudillo Miguel
- Atatri Yazid yousef mahmoud
- Atta Ahmed
- Attia Alaa Mobarak
- Avile Romina
- Avolio Luigi
- Awad Hadeel
- Aydin Emrah
- Aykut Merve
- Ayque Rosas Fernando
- Aziz Dayang Anita Abdul
- Ba'baa' Basheer
- Badr Helmy
- Baertschiger Reto
- Bagbio Dominic
- Bah Abdoulie
- Bai Qiang
- Bai Yu Zuo
- Baistrocchi Valentina
- Bakar Ainal Huda Abu
- Baker Wisam
- Ballouhey Quentin
- Balousha Abrar ghassan
- Bamanga Ahmed
- Baniowda Muath A. M.
- Bao Xiaozhou
- Barauskas Vidmantas
- Barbosa Patricia Reis
- Baseggio Natalia
- Bashir Fatma
- Bashir Muhammad Kashif
- Bassan Gonçalves Paulo César
- Bataineh Ziad A.
- Batal Mohammad Mohannad
- Bazozi Hana Milad
- Beasley Spencer
- Becker Karin
- Belmino Gadelha Aluísio Augusto
- Benaskeur Yousra-Imane
- Beres Alana
- Berková Klára
- Bernaus Marianela
- Berrocal Anaya Waldo
- Berzanskis Mindaugas
- Beshtawi Doha mustafa saleh
- Beşir Ahmet
- Bianchin Ezequiel
- Bibas Fatma
- Biber Elna
- Bischoff Cristiano
- Bismarck Sylvester von
- Blain Otilia Eva
- Blanc Thomas
- Blazquez-Gomez Eva
- Bobadilla Morales Lucina
- Bode Christopher
- Bonnard Arnaud
- Boonthai Ampaipan
- Borbonet Daniel
- Bouhadiba Nordeen
- Bowder Alex
- Bracho Blanchet Eduardo
- Bradshaw Kate
- Bragagnini Paolo
- Brahmamdam Pavan
- Bravo Mauro Nicolas
- Bright Benedict Paul
- Brito Quevedo Luz Mery
- Broch Aline
- Brolin Santis Isolan Paola Maria
- Brunero Marco
- Bruxel Carla Luisa
- Bsisu Isam
- Bucaram Elena
- Bueno Mazzuca Rafael
- Bueno Motter Sarah
- Bujarimin Ahmad Shafiee bin
- Bulnes Mendizabal David
- Burks Stephen S.
- Burns Kate
- Butler Marilyn
- Bvulani Bruce
- C. Nwosu David
- Caamal Lorenzo Juvencio
- Calancea Calin
- Calderon Moore Antonio
- Calderón Arancibia José Alfredo
- Calistus Nwachukwu
- Cama Jitoko
- Camamra Kajali
- Cameron Fraser
- Camp Lauren
- Canözer Ali
- Caouette-Laberge Louise
- Cardenas Alva Loreley Raquel
- Cardenas Ruiz Velasco Juan Jose
- Carrasco Ana Lucia
- Carrasco-Ortega Cesar
- Carrillo Isabel
- Casado Francis Tanise
- Casal Beloy Isabel
- Caseb Paloma
- Casquero Victor
- Castañeda Espinosa Sergio
- Castaño Avila Daniela
- Castedo Camacho Fabiola Ruth
- Cavaiuolo Silvia
- Cañapataña Sahuanay Veronica Raquel
- Cepeda Rodrigo
- Cesur İlknur Banlı
- Chan Jonathan
- Chang Jeremy
- Charras Maria Delia
- Chaudary Ali Raza
- Chaudhry Muhammad Amjad
- Chauhan Nirav
- Chavez Galvez Patricia
- Chen Lulu
- Chen Rui
- Cheung Maija
- Chipalavela Rossana Francisco
- Chiriboga Elena
- Chitiavi Soita Wycliffe
- Chitnis Milind
- Cho Seok Hyeon
- Choo Candy SC
- Chukwu Isaac
- Chukwuemeka Anyanwu Lofty-John
- Chung Jae Hee
- Cletus Cyril
- Coghill Griffin
- Collins Nwokoro
- Colombo de Holanda Felipe
- Contreras Carla Sofia
- Coon John
- Cordonnier Annelien
- Cornelli Fabio
- Cornwall Hannah
- Corona C. Rivera Jorge Román
- Corona Rivera Alfredo
- Correa Leite Mila Torii
- Correa Armandou
- Correa Catalina
- Corrêa Costa Eduardo
- Cosoreanu Vlad
- Costas-Chavarri Ainhoa
- Cripovich Alejandrina
- Cunningham Aaron
- Czauderna Piotr
- Cáceres Aucatoma Freud
- Cárdenas Barón José de Jesús
- Cömert Hatice Sonay Yalçın
- da Silva Augusto Maria Lucia
- Dagilytė Rūta
- Dahman Nesrine Ben Hadj
- Dajia Wang
- Dalek Noor Fa'izatul Rahil Ambok
- Dallegre Maria Belen
- Dalloul Hisham
- Damiani Andrea
- Dammagh Nagham Mohammed Al
- Dania Bouguermouh
- Darras Osama Majed
- Darwish Ahmed S
- Darwish Ammar
- Dass Anthony
- Dassonville Martine
- Davenport Kate
- David Kuria
- Davies Justine
- Davis Jenna Kylene
- de Assis Silva Murilo
- de Azevedo Belesa Flavia
- de Campos Vieira Abib Simone
- de Deus Passos Leles Kamila
- de Guzman Johann
- de Souza Santos Ferreira Mariana
- Dedeke Florence
- Defago Victor Hugo
- Defert Coralie
- Delefortrie Thomas
- Delforge Xavier
- Delft Dirk von
- Delgado Malaga Florangel Patricia
- Delgado Quinteros Edgar Fernando
- Dellenmark Blom Michaela
- Dendusic Nejra
- Derbew Miliard
- Derks Terry
- Deya Corazone
- Deyab Abdelaziz
- Di Siervi Oscar
- Diaz Castañeda Flor de Maria
- Diaz Echegaray Marlene
- Diaz Gomez Jose Manuel
- Diaz Leon Cesar
- Dieudonné Lemfuka
- Dimatatac Doris Mae
- Djordjevic Ivona
- Dogar Sohail
- Doheim Mohamed Fahmy
- Dominguez Danny
- Donglai Hu
- Dornellas do Nascimento Suely
- dos Santos Dias André Iván Bradley
- Dosselman Luke J.
- Douiri Abdel
- Drah Weam
- Dube Andile Maqhawe
- Duchesne Camille
- Duggan Eileen
- Duote Cai
- Dure Carolina
- Dávila Perez Roberto
- Ebeido Annan
- Egbuchulem Ifeanyichukwu Kelvin
- Ejinkeonye Eze Chukwuemeka
- Ekenze Sebastian Okwuchukwu
- Ekwunife Okechukwu Hyginus
- El-Ghazaly Mohammed
- Elassall Gena Mohamed Hamed
- Elayeb Abdallah
- Elebute Olumide Abiodun
- Elewaily Mohamed
- Elfiky Mahmoud
- Elgammudi Mala
- Elghazaly Shrouk Mahmoud
- Elhadi Ahmed
- Elhadi Muhammed
- Elhajjaji Yasmine Ali
- Elhattab Ahmad
- Elisante Joseph
- Elkaloush Abdullahn Abdousalam
- Elkhazmi Ebtesam Othman Abdulsalam
- Elmenam Mohamed Abd
- Elmzyyen Aya Mahmoud
- Elrais Safa Abdal
- Elsadek Menan Ahmed
- Elsaied Adham
- Elshaer Omar Adly
- Elsherbiny Mohamed
- Elsiraffy Omar Ossama
- Elstad Maria
- Elzohiri Mohamed
- Elzowawi Fathi
- Emam Omar Sameh
- Emil Sherif
- Enbaya Manal Ben
- Ensar Nicholas
- Erdem Melisa
- Eren Elif
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- Essamilghi Kamila Almabrouk Mohammed
- Ezidiegwu Ugochukwu S
- Ezomike Uchechukwu Obiora
- Faboya Omolara Moronkeji
- Fachin Camila
- Fadhle Muhamed Jassim
- Faks Vivian
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- Farag Eman mohamed
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- Fox Sarah
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- Furtado Mariana
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- Gall Caroline Le
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- Ghanem Waleed H.
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- Hall Timothy
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- Hammond Philip
- Hammouri Ahmad G.
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- Han Yijiang
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- Hassan Mohamed Abada
- Hassan Mohd Razin bin
- Hassan Zulfitri bin Md
- Herappe Mellado Dorihela
- Herdan Mohamed Omar
- Hernández Córdova Karina
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- Herrera Carina
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- Hinostroza Daniel
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- Huang Liuming
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- Huang Ting
- Huaytalla Quiroz Natalia
- Huespe Enrique
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- Hussein Omar Ghazi
- Hussein Sara Al
- Hussien Muaad
- Hwang In ji
- Hyeon Cho Seok
- Hyman Gabriella
- Ibarra Daniel
- Ibrahim Eman Abouzeid Abouzeid
- Ibrahim Fowzia
- Ibrahim Mahmoud abdelshakour
- Ibukunolu Ogundele
- Igoche Matthias
- Ihediwa George
- İmamoğlu Mustafa
- Ionescu Sebastian
- Iracelay Susana
- Iriondo Martí
- Ishak Shareena
- Ismail Enas Musa
- Ismavel Vijay Anand
- Itangishaka Innocent
- Ivanov Monica
- Jabaiti Mohammad S.
- Jabang John N.
- Jaber Dania
- Jacobson Jillian
- Jain Sunil
- Jaiteh Musa
- Jallow Cherno S.
- Jalo Iliya
- Jamal Muhammad Umer
- Jamie Najlaa Abu
- Jamie Yasmin Mohammed Khalil Abu
- Jaramillo Martha
- Jauri Cesar
- Jayaratnam Sridharan
- Jayyab Mustafa abu
- Jester Ingo
- Jimenez Morejon Vinicio
- Joda Ali Egab
- Joharifard Shahrzad
- Johnson Stephanie
- Jones Brendan
- Jones Ceri
- Jones Matthew
- Jonuzi Asmir
- Jooma Uzair
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- Karakus Suleyman Cuneyt
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- Karim Sabbir
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- Kayed Yara Imad Omar
- Kayibanda Emmanuel
- Kchiche Nahla
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- Khalid Hazlina Mohd.
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- Khatatba Lara Zahi Adel
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- Kufeji Dorothy
- Kukkady Askar
- Kumar Vijay
- Kumolalo Felix O.
- Kunfah Sheba Mary Pognaa
- Kurian Merina
- Kurt Gökmen
- Kwasau Henang
- Laberge Jean-Martin
- Labonia Carla
- Ladipo-Ajayi Oluwaseun
- Lahlooh Raghad abdullateef
- Lakhoo Kokila
- Lander Tony
- Landivar Cino Enrique
- Langer Monica
- Langley Jason
- Lapouble Francisco
- Lara Sandra
- Laraqui Hossini Samia
- Latiff Zarina Abdul
- Lawal Taiwo
- Lawalbarau Abdullahi
- Layas Tesneem
- Laymouna Moustafa A.
- Leal Paola Osses
- Leather Andrew J. M.
- Lechmiannandan Abhirrami
- Ledesma Peraza Jesmarina
- Lee Ju yeon
- Lee Sanghoon
- Leech Mary
- Lerma Sergio
- Letic Emina
- Levard Guillaume
- Levitt Marc
- Leyba Marcos Federico
- León Frutos Francisco Javier
- Li Haijing
- Li Shungen
- Li Zhongrong
- Liang Liang
- Liljesthrom Karen
- Lim Felicia
- Lin Nicole
- Lindert Judith
- Lino Urquizo Marcelo Mauricio
- Liu Yang
- Liubsys Arunas
- Liukitithara Sirima
- Ljuhar Damir
- Llap Unchón Genaro
- Lobos Pablo
- Lodhia Jay
- Loo Neyra Maria Susana
- Lopes de Almeida Thayná
- Lopes Teixeira Ferdinando Danielle
- Losa Gabriela Natalia
- Losty Paul
- Lotfollahzadeh Saran
- Loyola Ferreira Julia
- Lu Jinjing
- Lubbad Walaa
- Lucio Palazzi
- Lui Yang
- Lukac Marija
- Lule Joseph
- Luo Wenjuan
- Lv Junying
- Lv Zhibao
- Lyttle Bailey D.
- Løfberg Katrine
- M. Ballah Abubakar
- M. Qabaja Mahmoud
- Mac Carlos
- Macdonald Alex
- Machemedze Solomon
- Madieh Jomana
- Madziba Sanele
- Mahmoud Ahmed Mokhtar
- Mahmud Khalid
- Mahmud Refoyez
- Mairami Amsa B.
- Maistry Niveshni
- Makhmud Aliev
- Malcius Dalius
- Malik Janan
- Malik Sawazen
- Mancera Juliana
- Mangray Hansraj
- Manirambona Emery
- Manjira Emmanuel
- Manni Francesco
- Mansfield Sara
- Mansour Islam
- Mansour Mohamed Awad
- Marcos Dolores
- Marianella Depetrini
- Marmol Monica
- Marta Osowicka
- Martin Aranda Diego
- Martin Benjamin
- Martinez-Leo Bruno
- Martins Bianca M. R.
- Martínez Hernández Magro Nestor
- Mary Koshy Roshine
- Massry Nasrallah Ashraf Al
- Matour Bashar M.
- Mayaleh Abdelrazzaq Abu
- Mbonicura Jean Claude
- Mbonisweni Akhona
- Mccluney Simon
- McColl Makepeace Lydia
- Medard Pablo
- Meftah Asma
- Melo Gallindo Rodrigo
- Meloche-Dumas Léamarie
- Mena Adriana
- Mendez Benavente Carolina
- Mendoza Chiroque Carlos
- Mendoza Leon Nancy Rossana
- Mendoza Oviedo Juan Jose
- Menin Flavio Augusto
- Mercado Pedro
- Mert Mustafa Kurthan
- Merwe Elmarie vd
- Mesas Burgos Carmen
- Mesic Amira
- Michael Vishal
- Middlesworth William
- Middleton Thomas
- Mieres Carlos
- Mikneviciute Agne
- Milisic Emir
- Millán Carolina
- Miriam Ann
- Mironescu Aurel
- Mirza Muhammad Bilal
- Misk Rami Anwar
- Mitul Ashrarur
- Mitul Ashrarur Rahman
- Modekwe Victor
- Modi Varun
- Mohammad Mohammad Aminu
- Mohammed Abobaker
- Mohammed Azhar Arabi
- Mohammed Hanan Mahmoud
- Mohammed Mansour Mkayed
- Mohammed Ola Ahmed Abdulmjeed
- Moitt Natalie
- Molina Vazquez Maria Elena
- Molina Marcelo
- Molinelli Matilde
- Monawar Abdul Baqi
- Montalvo Marin Arturo
- Montoya Debora
- Mora Maria
- Moraes Mario
- Morales Adriana
- Morales Otto
- Moreno Maria Eugenia
- Moriya Eliane
- Morjan Mohammed
- Mose Moraa
- Motee Jethishka
- Motter Sarah Bueno
- Mounira Baghdadi Nour el islam
- Mouti Mohamad Bassel
- Mouttalib Sofia
- Mshelbwala Philip Mari
- Msuya David
- Mugambi Stanley
- Mugo Robert
- Muhic Amila
- Mulu Jack
- Mumtaz Uzma
- Muntean Liviu
- Murad Amir M. I.
- Muradi Teymursha
- Muragijimana Jean De Dieu
- Muraveji Qais
- Murillo Ericka
- Murshidi Raghad M.
- Murtadi Habib Mansour
- Murzaie Muhammad Yousuf
- Muslimovich Aliev Makhmudjan
- Mussein Haidar Mohammad
- Mustufa Hamassat
- Mutlu Mehmet
- Muñoz Guillermo
- Mvukiyehe Jean Paul
- Mwai Timothy
- Nageh Mohammad
- Nah Shireen Anne
- Naidoo Rasika
- Naim Nur Atifah binti Mohd
- Naim Samy Rafat Ramadan
- Naranjo Kelly
- Nassar Ismail
- Nataraja Ramesh M
- Naumeri Fatima
- Naunova Vesna Cvetanovska
- Ndata Albert
- Ndayishimiye Isaac
- Ndungu James
- Negash Samuel
- Negida Ahmed
- Negrete Amalia
- Nemer Rawan
- Nezerwa Yves Castar
- Ngerncham Monawat
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- Nkuliza Delphine
- Nkunzimana Elysé
- Nofal Ahmed Hassan
- Nogueira Marques Geraldo Magela
- Noguez Castillo Monica
- Noor Wan Ruzaimie
- Nor Mohd. Tarmizi Mohd
- Norberto da Silva Juliana Antinarelli
- Nour Ibrahim
- Nour Ibrahim R.
- Nour Ibrahim Rabi
- Novochadlo Klüppel Elis
- Novotny Nathan
- Nunes Kist Iuri
- Nuntasunti Wasun
- Nwangwu Emmanuel Ifeanyi
- Nwankwo Elochukwu Perpetua
- O'Connor Jennifer
- O'Connor Zachary
- Obianyo Nene Elsie
- Ochieng Kevin
- Ochieng Roseline
- Odi Abd Al-Naser Bany
- Ogundoyin Olakayode
- Olabisi Osagie O
- Olanrewaju Moses
- Olayade Kayode
- Oliu San Miguel Detlef
- Oliveira de Andrade Susy
- Oliveira Danielle Paula de
- Olivos Perez Maricarmen
- Olori Samson
- Olulana Dare I.
- Omari Rand Y.
- Omendo Liyenzero Polycarp
- Omling Erik
- Ormeño Calderón Luis
- Orozco Perez Jamie
- Ortega Sotelo Luis
- Ortiz Argomedo María Rosa
- Osagie Olabisi
- Osazuwa Maryrose
- Oshiba Ahmed Mohamed
- Osman Marjmin
- Osorio Fory Ghordana
- Osowicka Marta
- Osuigwe Andrew N
- Osuoji Roland Iheanyichukwu
- Othman Mohd Yusran Bin
- Otuneye Adekunle T.
- Outani Oumaima
- Owiwi Yazeed
- Owusu Sheila
- Owusu-Sekyere Frank
- Oyebanji Lateef
- Oyinloye Adewale
- Ozen Mehmet Ali
- Pachl Max
- Pajouhandeh Fatemeh
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- Pardy Caroline
- Paredes Espinoza Patricia
- Parigi Gian Battista
- Parker Samuel
- Parmentier Benoit
- Pasaoglu Mehmet
- Pasierbek Michal
- Pasqua Noemi
- Patel Azad
- Patiño Gonzalez Celeste Carolina
- Patkowski Dariusz
- Patzer Ludwig
- Pauzi Siti Farhan Moh
- Paz Soldan Carolina
- Pernik Mark N.
- Peycelon Matthieu
- Peña Padilla Christian
- Peñarrieta Daher Alejandro
- Phannua Ratiyaporn
- Philipo Godfrey Sama
- Piché Nelson
- Pigeolet Manon
- Pilkington Mercedes
- Pinar Brooke
- Piotrowska Aneta
- Planka Ladislav
- Poenaru Dan
- Ponce Fajardo Gabriela Yulissa
- Poocharoen Wannisa
- Popovic Nusret
- Porras Juan Domingo
- Pos Lucie
- Prabhu P Santosh
- Prat Jordi
- Prieto Vargas Osbaldo
- PT Sundeep
- Puentes Maria Consuelo
- Puglia Paul
- Puig Maria Gabriela
- Puligandla Pramod
- Putruele Daniel
- Qadomi Asef belal
- Qawwash Anas
- Qi Dr. Tammy Teoh Han
- Qudah Hamzah Abullah
- Quiles Corona Moises
- Qunaibi Moradallah Asad Fahmi
- Quran Thekraiat M. Al
- Qureshi Taimur
- Qutishat Hibah
- Qwaider Yasmeen Z.
- Raboe Enaam
- Racková Tereza
- Radwan Asaad saleh
- Raffaele Alessandro
- Raicevic Maja
- Raj Ankit
- Ramirez De La Cruz Raul
- Ramli Najua binti
- Ramos Paredes Erika
- Ramos Yna
- Rani Zarqa
- Rasaki Aliu
- Rashid Sakina
- Rashwan Hayssam
- Ravetta Pablo
- Ravi Krithi
- Raymond Kwizera Jean
- Raza Rafee
- Razak Rahilah binti Abd
- Reda Ahmed
- Rehman Wajeeh ur
- Renaux Petel Mariette
- Rengura Cecilia
- Reuter Cristina
- Rex Dean
- Rezende Rosa Bianca
- Rhodes Hannah
- Ribas Bianca
- Ribeiro de Fernández y Alcázar Fernanda
- Riboni Cristiana
- Rieth Anna
- Rincon Luis Carlos
- Rios Flores Izabel Maryalexandra
- Rissmann Anke
- Risteski Toni
- Rite Segundo
- Rivarola Nahuel Ignacio
- Rivera Altamirano Porfirio
- Rivera Alvarez Julio
- Roberts Charles A.
- Roberts Kiera
- Roberts Rebecca
- Rojas Nair
- Rolle Udo
- Romano Piero Giovanni
- Romero Manteola Enrique
- Roszkiewicz Anna
- Ruan Weiwei
- Rudolfson Niclas
- Ruiz de Temiño Bravo Mercedes
- Ruzgar Nensi
- Rygl Michal
- S. Alkali Yahya
- Saad Alshaimaa M.
- Saad Mahmoud M.
- Sabbatini Stella
- Sabic Adnan
- Sabti Shahad
- Sadagurschi Mariana
- Sadek Kareem
- Sadek Mirna
- Safa Nadia
- Sahnoun Lassaad
- Salah Mohammed
- Salawu Morayo Monsurat
- Salazar Karla
- Saldaña Lily
- Saleem Ayesha
- Saleem Muhammad
- Saleh Amr
- Saleh Mahmoud
- Salem Hosni khairy
- Salha Aya Azmi Shehda
- Salim Jamal Mohammed
- Salinas Barreto Juan Jose
- Salinas Vicente
- Salö Martin
- Samad Lubna
- Samadi Dr. Ahmad Zia
- Samanez Obeso Angel
- Samarah Yasmeen Ahmad
- Samarakkody Udaya
- Samy Doaa
- Sanchez Valladares Pablo
- Sanchez Alberto
- Sanchez Beatriz
- Sanchez Janina
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- Santana Ortiz Rafael
- Saousen Benmanseur
- Sara Nabti
- Saracevic Adna
- Sarhan Osama Abdul Kareem
- Sarıhan Haluk
- Sarkaz Taher L.
- Sartori Giovanoni Lais
- Sayeed Fatema
- Sbaih Mahmoud Fuad
- Scalabre Aurelien
- Scherl Humberto
- Schmedding Andrea
- Segura Calle Carlos
- Sehic Anesa
- Sehwiel Abrar Shaheen
- Sekyere Owusu
- Selak Nejra
- Semensato Carloni Isabela Cristina
- Sempertegui Denisse
- Serban Andreea Madalina
- Serezo Belen
- Sevdalis Nick
- Seyi-Olajide Justina
- Sferco Carlos Ariel
- Shabana Osaid Shaher
- Shahbal Swaleh
- Shaheen Ahmad Ashraf
- Shaheen Nureddin
- Shaklawoon Aisha
- Shalaby Amr
- Shalaby Hanin
- Shalluf Hawa Ahmed
- Shan Cheah Hui
- Sharabati Fadwa
- Sharabati Mutassem
- Sharif Muhammad
- Sharif Randa Alamen M
- Shaw Kenneth
- Shehada Mohammed
- Shehu Ibrahim
- Sheir Hesham
- Sherer Karen
- Sherzad Ajmal
- Shiha Eman Abu
- Shikha Anas
- Shinondo Patricia
- Shnishah Aya Essam
- Shokri Hajer Ali
- Shonubi Amo
- Shoubaki Ali
- Shu Qiang
- Shyaka Gashugi Ian
- Siddiqui Sabina M
- Sidler Daniel
- Sigalet David
- Sihem Brahimi
- Sikwete Guigui
- Siles Hinojosa Alexander
- Silva Beltrán Nathalia
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- Silva Julian
- Silva Karina Ilheu da
- Silva Yanina
- Sim Marcus
- Simeon Turatsinze
- Simon Soledad
- Sindi Omar
- Singer Georg
- Singh Michael
- Sivaraj Jayaram
- Sivasubramaniam Mithila
- Siyotula Thozama
- Slavkovi Andjelka
- Slavkovic Milan
- Smith Emily Rose
- Soares de Fraga José Carlos
- Sobrero Helena
- Soccorso Giampiero
- Sokolovic Emir
- Sola Juan
- Solanki Meghna
- Soliman Nourhan Akram
- Son Joonhyuk
- Song Eung song
- Soomro Aqil
- Sotelo Sanchez Jennifer
- Souhem Touabti
- Soula Enas
- Souza Barros Beatriz
- Souza Machado Ana Beatriz
- Sowe Babucarr
- Sriniworn Anan
- St-Louis Etienne
- St-Vil Dickens
- Stark Domitille
- Stojanovic Miona
- Stringer Mark
- Strumila Arunas
- Sueiras Ines
- Sulca Cruzado Gladys Johana
- Suleiman Faruk
- Sultana Sadia
- Suradi Haya H.
- Sutcliffe Jonathan
- Suzana Trein Cristine
- Suzen Alev
- Svensson Emma
- Svirsky Alexander
- Swessi Hisham
- Syed Shahnoor
- Syovata Francisa
- Szklarz Maria Tatiana
- Sánchez Paredes Vicente
- Sönmez Kaan
- T Shajin
- T. Sambo Yusuf
- Tababa Osama
- Tabari Ahmad Khaleghnejad
- Tabiri Stephen
- Tadesse Amezene
- Tahyneh Abdulraheem Adnan Abdulraheem
- Takrouney Mohammed Hamada
- Talat Nabila
- Tallaa Mohamed Anwer El
- Tamada Horácio
- Tamaddun Hafatin Fairos bt
- Tang Weibing
- Tanimola Adebayo Gbenga
- Tanming Patchareeporn
- Tanny Sharman Tan
- Tantush Sara Abobaker
- Tarabishi Ahmad Sankari
- Tarek Ahmed
- Tarmohamed Murad
- Tarniba Sara Ali
- Tarrado Xavier
- Tasker David
- Teague Warwick
- Telles Leila
- Temilade Bolarinwa Bolanle
- Teo Rufinah
- Teran Araceli
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- Testoni Daniela
- Thaiwatcharamas Kanokrat
- Thiessen Jesh
- Thomas Amy Hughes
- Thomas Gordon
- Thomas Mark C
- Thompson Hannah
- Till Holger
- Tillig Bernd
- Tinoco Guzmán Nestor Julien
- Tobor Szymon
- Toczewski Krystian
- Tom Alan
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- Torres Picón Cintya Maria de Jesus
- Torres-Canchala Laura
- Toselli Luzia
- Touabti Souhem
- Toufik Iaiche Achour
- Tovar Gutierrez Natalia
- Trainba Sara
- Trigoso Mori Fernando
- Trindade Deyl Rafael
- Trojanová Barbora
- Trypens Agata
- Tumi Mohamed
- Tuyishime Eugene
- Türkyılmaz Canan
- Türkyılmaz Zafer
- Ubhi Harmony
- Ugwu Jideofor O
- Ugwunne Chuka A
- Ulasi Ikechukwu
- Ullrich Sarah
- Vacek Jonathan
- Vaitkiene Agota
- Valencia Santiago
- Valeria Pelussi
- Valerio-Vazquez Rafael
- Vanis Nedim
- Vaquila Justo
- Varela Maria Florencia
- Vasquez Matos Juan Pedro
- Vatta Fabrizio
- Vega Centen Stephany
- Velaña Junior
- Vellusamy V Muthualhagi M
- Venant Ntakarutimana
- Venkatraman Soundappan Sannappa
- Verdeata Roxana
- Verduga Ivan
- Verduga Leonardo
- Vergara Carolina
- Verkauskas Gilvydas
- Veronica Sofficci
- Vervoort Dominique
- Vianney Butoyi Jean Marie
- Vida Lucian
- Vidal Cristian R. Zalles
- Vierboom Liam
- Villalba Villalba Araceli
- Villegas Silva Raúl
- Vinskaite Asta
- Vos Corné de
- Vosoughi Armin
- Wafa Tamer
- Walker Gregor
- Wang Jinhu
- Wang Peng
- Waseem Basma
- Weeratunga Naveen
- Weiszewsk Alicja
- Wen Gang
- Werneck Raposo Juliana
- Wester Tomas
- Wijekoon Naveen
- Wilke Alexandra
- Williams Isabelle
- Williams Omolara
- Williams Regan
- Win Win Sabai Phyu
- Wishah Bisan D. M.
- Wishah Nidal
- Wissanji Hussein
- Wolak Przemyslaw
- Wolny Agnieszka
- Wong Janice
- Wong Marilyn
- Wright Naomi Jane
- Wu Guowei
- Wyrzykowski Dariusz
- Xiaodong Guo
- Xie Hua
- Yacoub Mina A.
- Yaghi Bashar
- Yaghi Dua Hasan
- Yalcinkaya Ali
- Yang Hee-Beom
- Yanis Ahmad H.
- Yanowsky Reyes Guillermo
- Yao Yang
- Yapo Benjamin
- Yarza Fernández Jessica
- Yeniay Aslı Öztürk
- Yola Mariya Mukhtar
- Yong Feng
- Youn Joong Kee
- Yousuf Hina
- Yu Mengnan
- Yu Raisa
- Yuen Quah Soong
- Yuldashev Rustam Z.
- Yunus Aayenah
- Za'nouneh Faris J. Abu
- Zaghlol Louay Y.
- Zahari Dato' Dr Zakaria bin
- Zain Mostafa
- Zaman Azrina SK
- Zanellato Josiane Bernartt
- Zarwawi Ahmad Zulhisyam bin
- Zea-Salazar Luis Enrique
- Zeinelabdeen Ali
- Zhao Xiaoxia
- Zhu Jianming
- Zhu Libin
- Zidan Mazen
- Zivanovic Dragoljub
- Zottis Barcelos Fabricio
- Zreeg Dafer abdulhakim . S.
- Zurikat Rajai O.
- Zvizdic Nada
- Zvizdic Zlatan
- Çekiç Bahanur
- Çelik Müge
- Özçelik Zerrin
- Şeref Kıvanç
- Šafus Antonín
- Škvařil Jan
- Štichhauer Radek
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
FLoBC: A Decentralized Blockchain-Based Federated Learning Framework
- Publication venue
- Publication date
- 22/12/2021
- Field of study
The rapid expansion of data worldwide invites the need for more distributed
solutions in order to apply machine learning on a much wider scale. The
resultant distributed learning systems can have various degrees of
centralization. In this work, we demonstrate our solution FLoBC for building a
generic decentralized federated learning system using blockchain technology,
accommodating any machine learning model that is compatible with gradient
descent optimization. We present our system design comprising the two
decentralized actors: trainer and validator, alongside our methodology for
ensuring reliable and efficient operation of said system. Finally, we utilize
FLoBC as an experimental sandbox to compare and contrast the effects of
trainer-to-validator ratio, reward-penalty policy, and model synchronization
schemes on the overall system performance, ultimately showing by example that a
decentralized federated learning system is indeed a feasible alternative to
more centralized architectures.Comment: BSc Computer Engineering Thesis [AUC, Spring 21
Correction to: Anterolateral ligament reconstruction improves the clinical and functional outcomes of anterior cruciate ligament reconstruction in athletes
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
ViSHWaS: Violence Study of Healthcare Workers and Systems—a global survey
- Author
- Aisha Khalid
- Akshat Banga
- Alicja Rydzewska Rosolowska
- Alisha Lakhani
- Amuza Dhabuliwo
- Anasonye Emmanuel
- Anne Kampa
- Arash Nemat
- Ayesha Khalid
- Ayushi Mendiratta
- Barakat Kolawole
- Bello Saifullah Muhammad
- Benjamin Schlenker
- Bhaswanth Bollu
- Bikona Ghosh
- Christos Tsagkaris
- Daniel Martin Simadibrata
- Daniella Myriam Pierre
- Daren Poh How
- Dattatreya Mukherjee
- Dimitrios Kantas
- Divya Randhawa
- Dohha Mohammed
- Era Mae Ramirez
- Faisal A Nawaz
- Faisal Nawaz
- Faizan Ahmad
- Franz Lopez
- Gaurang Bhatt
- Genesis Camacho-Leon
- Goodluck Nchasi
- Gowthami Sai Jagirdhar
- Hafeez Hamza
- Hans Mautong
- Harsha Pattnaik
- Hassan Dawood Alli
- Hedys Selene Mogollón
- Hussein Dawoud
- Ishimwe Florent
- Ivan Huespe
- Joanna Lee
- John Counsell
- Jonida Naska
- Jorge Salluh
- Kalloush Shahed
- Keidy Zamora
- Kelly Maza
- Kelly Meza
- Kush Shah
- L V Kutikuppala
- L V Simhachalam Kutikuppala
- L V Simhachalam Kutikuppala
- Leydi Del Lema
- Lina Almahmoud
- Lisdamys Morera Gonzalez
- Marco Antonio Villar
- Mariam Elsaban
- Marija Vukoja
- Melissa Schlenker
- Moath Almekhlafi
- Mohamed Elfagieh
- Mohammad Yasir Essar
- Mohammed Alkawak
- Mohammed Amir Rais
- Mohammed Yasir Essar
- N Pierre Ciza
- Nancy Nagib
- Naresh Dasari
- Nimsi Barrios
- Oyindamola Obadare
- Pierre Ciza N
- Piyush Garg
- Pranjal Sharma
- Pratikkumar Vekaria
- Priyadarshini Bhattacharjee
- Raghavendra Tirupathi
- Raghu Gandhi
- Rahul Kashyap
- Rakhtan K Qasba
- Rakhtan Qasba
- Ramesh Adhikari
- Ramesh Pandit
- Ramesha Remy
- Ravina Verma
- Razan Alamoudi
- Reshon Hadmon
- Rodrigue Ndabashinze
- Salem Ramirez
- Salim Surani
- Sama Soliman
- Sarya Swed
- Shehu Bledi
- Srdjan Gavrilovic
- Susan Okonkwo
- Susan Sheila
- Taha Mansoor
- Tanja Kovačević
- Tanya Amal
- Taru Dutt
- Temaa Alklani
- Trupti Pandit
- Umme Faisal
- Umme Habiba Faisal
- Usama Oguz
- Vikas Bansal
- Yosra Magdi Makki
- Zainab Ayoob
- Zeynep Pelin Orhan
- Publication venue
- BMJ Publishing Group
- Publication date
- 01/09/2023
- Field of study
Objective To provide insights into the nature, risk factors, impact and existing measures for reporting and preventing violence in the healthcare system. The under-reporting of violence against healthcare workers (HCWs) globally highlights the need for increased public awareness and education.Methods The Violence Study of Healthcare Workers and Systems study used a survey questionnaire created using Research Electronic Data Capture (REDCap) forms and distributed from 6 June to 9 August 2022. Logistic regression analysis evaluated violence predictors, including gender, age, years of experience, institution type, respondent profession and night shift frequency. A χ2 test was performed to determine the association between gender and different violence forms.Results A total of 5405 responses from 79 countries were analysed. India, the USA and Venezuela were the top three contributors. Female respondents comprised 53%. The majority (45%) fell within the 26–35 age group. Medical students (21%), consultants (20%), residents/fellows (15%) and nurses (10%) constituted highest responders. Nearly 55% HCWs reported firsthand violence experience, and 16% reported violence against their colleagues. Perpetrators were identified as patients or family members in over 50% of cases, while supervisor-incited violence accounted for 16%. Around 80% stated that violence incidence either remained constant or increased during the COVID-19 pandemic. Among HCWs who experienced violence, 55% felt less motivated or more dissatisfied with their jobs afterward, and 25% expressed willingness to quit. Univariate analysis revealed that HCWs aged 26–65 years, nurses, physicians, ancillary staff, those working in public settings, with >1 year of experience, and frequent night shift workers were at significantly higher risk of experiencing violence. These results remained significant in multivariate analysis, except for the 55–65 age group, which lost statistical significance.Conclusion This global cross-sectional study highlights that a majority of HCWs have experienced violence, and the incidence either increased or remained the same during the COVID-19 pandemic. This has resulted in decreased job satisfaction
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
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- Abdelrahman Abdelrahman
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- Azize Diallo Abdoul
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- Balushi Nawf Al
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- Barnes Nicholas Adamson
- Bartolomé Santiago Alonso
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- Benhamou Rita Ait
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- Correia Bernardo
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- Costanzi Andrea
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- Costas-Ochoa Simbad
- Costea Radu
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- Costeira Cristina
- Costi Renato
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- Cotta Estefanía
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- Dahabrh Seif Al
- De Medeiros Jorge
- De Michele Federico
- De Nardi Paola
- De Nunzio Cosimo
- De Palma Alessandra
- De Palma Giovanni Domenico
- De Pano Jojiemar
- De Paola Gilda
- De Prizio Marco
- De Riu Giacomo
- De Robles Marie Shella
- De Rosa Raffaele
- De Santi Silvia
- De Silva Chathuranka
- De Silva Kanishka
- De Simone Belinda
- De Simone Veronica
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- De Vincenti Rosita
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- Del Basso Celeste
- Del Chiaro Marco
- Del Gaudio Massimo
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- Dhafif Anwaar Al
- Dhaheri Mahmood Al
- Dhoun Sajedah Al
- Dosouky Mohammed Al
- Draz Najib Abu
- Duhileb Mohammed Al
- El-Ghani Wael
- Elsayed Mustafa
- Elwahab Ahmed
- Elwahab Sami
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- Fernández Marta Alonso
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- García Fernando Acebes
- García Miguel Adeba
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- Ghafry Alaa Al
- Glasbey James
- Gohary Rawda Al
- González Francisco Andrade
- Gujjuri Rohan
- Gurumeta Alfredo
- Habes Hessa Al
- Hameed Jumana Abdul
- Hameed Najat Abdul
- Haq Zainab Ahmad
- Harthi Abdulaziz Al
- Hasan Ziad Aboharp
- Hilal Mohammed Abu
- Hosni Mohammed Al
- Humaid Lama Al
- Imaz Ainhoa Andres
- Ingabire Jc Allen
- Jamahir Mohammed Al
- Jarad Ziad Al
- Jarmozi Buthina Al
- Jawad Hussain Al
- Jayyab Mustafa Abu
- Juarranz Miguel Alonso
- Junior Joel
- Júnior Samuel Aguiar
- Kalbani Maha Al
- Kalbani Moza Al
- Kamarajah Sivesh
- Kharusi Lamya Al
- Kharusi Safiya Al
- Khassawneh Ahmad Al
- Koculen
- Köylü Zehra Alan
- Lahham Salim Al
- Lara Iván Andújar
- Lara María Adrien
- Li Elizabeth
- Lucas Miriam Abellan
- Maadany Faraj Al
- Mahdawi Leyla Al
- Mahdy Hossam Al
- Makari Reem Al
- Manji Adil Al-Karim
- Maqtari Siham Al
- Mariño Mauricio Agüero
- Martinez Yicel Alvarez
- Maryam A
- Matas Fernando Alcaide
- Mendoza Veronica Alonso
- Mensah Kwasi Agyen
- Mintah Dominic Annor
- Moagal Rehab Al
- Moawad Karim Abdelraouf
- Mohamed Mohamed Ali
- Mohsen Mustafa Abo
- Momani Tareg Al
- Muhfouz Dima Abu
- Muhtadi Fadhl Al
- Mulke Rahaf Al
- Murgueitio Natalia Cortes
- Mutani Mohammed Al
- Nafesa Aminah Al
- Nahian Syed Al
- Najjar Majed Al
- Najjar Tasneem Al
- Nami Awaji Al
- Nassar Saleh Al
- Nepogodiev Dmitri
- Neto Alfeu Accorsi
- Noval Patricia Corriols
- Nwijy Khaled Ai
- Obead Hamza Abu
- Oliver Renato Aguera
- Omair Shehanah Al
- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
- Ros Conrado Andrés
- Roselló Irene Vives
- Rubio Eva Corral
- Rueda Ignacio Alcalá
- Saad Sarah Ahmed
- Sabti Hilal Al
- Saez Iago Alvarez
- Saied Ghiath Al
- Salam Omar Abdul
- Salama Ibrahim Abdelkader
- Sanany Ghadeer Al
- Santos Daniel Costa
- Sayed Mohamed Al
- Sebastian Isabel Alonso
- Shaalah Ahmed Abdullah
- Shaibi Maha Al
- Shaikh Shafqat Ali
- Shanab Ahmed Abo
- Sharie Ahmed Al
- Shukri Asmaa Al
- Simoes Joana
- Smadi Omar Al
- Soares Rui Costa
- Soucheiron Maria Coronas
- Subaie Saud Al
- Suyyagh Kais Al
- Tarieh Ammar Abu
- Torres Eva Alvarez
- Victoria Czarlo Dela
- Villamayor Verónica Alen
- Vinayagam Raman
- Vincenti Cara
- Vincenzi Matteo
- Vinz Franziska
- Violante Tommaso
- Violas Philippe
- Violette Mukanyange
- Viotti Fabio
- Virdi Amrita
- Virgilio Edoardo
- Virgincar Ashwini
- Virta Ville P
- Viscido German
- Vishnoi Jeewan Ram
- Vishwakarma Sunil Kumar
- Vishwani Vartika
- Vissapragada Ravi
- Viste Claire
- Viswanath Yks
- Vitowanu Julius
- Viveiros Octavio
- Viveros-Carreño David
- Vives Inmaculada
- Vives-Barquiel Marian
- Vivian-Taylor Josephine
- Vix Michel
- Vlad Ioan Catalin
- Vlad Schitcu
- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population