Excavations in the Archaic Civic Buildings at Azoria in 2005-2006

Continuing excavation on the South Acropolis at Azoria in northeastern Crete has exposed buildings of Archaic date (7th–early 5th century b.c.) that served communal or public functions. Work conducted in 2005 and 2006 completed the exploration of Late Archaic levels within the Communal Dining Building (putative andreion complex), the Monumental Civic Building, and the adjacent Service Building. These contexts and their assemblages, especially the animal and plant remains, permit the characterization of diverse dining practices and the interpretation of patterns of food production and consumption. Both the Communal Dining Building and the Monumental Civic Building show extensive evidence of communal feasting and the integration of cult

Excavations at Azoria, 2003-2004, Part I: The Archaic Civic Complex

his article constitutes the first of two reports on fieldwork conducted at Azoria in eastern Crete during the 2003 and 2004 excavation seasons. The focus of excavation was on the South Acropolis, where buildings of Archaic date (7th-early 5th century b.c.) suggesting public or civic functions have come to light. The complex includes a possible andreion on the west slope, a cult building on the terrace south of the peak, and storerooms and kitchens associated with a monumental public building on the southwest terrace. A 3rd-century b.c. dump on the southeast slope provides important information about the limited reoccupation of the site in the Hellenistic period

President & Mrs. Truman, Margaret Truman, Secretary & Mrs. John W. Snyder and Drucie Snyder to Senator & Mrs. James O. Eastland, 5 January 1949

Copy printed invitation from President & Mrs. Truman, Margaret Truman, Secretary of the Treasury & Mrs. Snyder, & Drucie Snyder to Honorable and Mrs. James O. Eastland, re: reception on 21 January 1949. Envelope postmarked 5 January 1949. Original removed to VIP Restricted Access Location.https://egrove.olemiss.edu/joecorr_b/1010/thumbnail.jp

Using the media for family planning

For more about the East-West Center, see http://www.eastwestcenter.org/</a

Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest.

Brain mural cells regulate development and function of the blood-brain barrier and control blood flow. Existing in vitro models of human brain mural cells have low expression of key mural cell genes, including NOTCH3. Thus, we asked whether activation of Notch3 signaling in hPSC-derived neural crest could direct the differentiation of brain mural cells with an improved transcriptional profile. Overexpression of the Notch3 intracellular domain (N3ICD) induced expression of mural cell markers PDGFRβ, TBX2, FOXS1, KCNJ8, SLC6A12, and endogenous Notch3. The resulting N3ICD-derived brain mural cells produced extracellular matrix, self-assembled with endothelial cells, and had functional KATP channels. ChIP-seq revealed that Notch3 serves as a direct input to relatively few genes in the context of this differentiation process. Our work demonstrates that activation of Notch3 signaling is sufficient to direct the differentiation of neural crest to mural cells and establishes a developmentally relevant differentiation protocol

Excavations at Azoria, 2002

This report summarizes the results of the first season of excavation at Azoria in eastern Crete and provides an overview of the project's goals and problem orientation. Work in 2002 concentrated on the peak of the South Acropolis and the occupational phases of the seventh-sixth centuries B.C. The recovery of a possible andreion complex suggests the urban character of the site in the sixth century and forms a starting point for discussing the political economy of the Archaic city. The excavations revealed important evidence for the organization of the sixth-century settlement and for the complex stratigraphic history of the site, including the Final Neolithic, Late Prepalatial, Early Iron Age, Archaic, and Hellenistic periods

Excavation of Archaic Houses at Azoria in 2005-2006

This article reports on the excavation of Archaic houses (6th-early 5th century b.c.) in 2005 and 2006 at Azoria in eastern Crete. Five houses are discussed: four on the South Acropolis on the periphery of the civic center, and one on the North Acropolis. Well-preserved floor deposits provide evidence for room functions and permit a preliminary analysis of domestic space. The houses fill a lacuna in the published record of the 6th and early 5th centuries b.c. and contribute to our understanding of the form of Archaic houses in the Aegean and the integration of domestic space into an urban context

Directing diarrhoeal disease research towards disease-burden reduction

Despite gains in controlling mortality relating to diarrhoeal disease, the burden of disease remains unacceptably high. To refocus health research to target disease-burden reduction as the goal of research in child health, the Child Health and Nutrition Research Initiative developed a systematic strategy to rank health research options. This priority-setting exercise included listing of 46 competitive research options in diarrhoeal disease and their critical and quantitative appraisal by 10 experts based on five criteria for research that reflect the ability of the research to be translated into interventions and achieved disease-burden reduction. These criteria included the answerability of the research questions, the efficacy and effectiveness of the intervention resulting from the research, the maximal potential for disease-burden reduction of the interventions derived from the research, the affordability, deliverability, and sustainability of the intervention supported by the research, and the overall effect of the research-derived intervention on equity. Experts scored each research option independently to delineate the best investments for diarrhoeal disease control in the developing world to reduce the burden of disease by 2015. Priority scores obtained for health policy and systems research obtained eight of the top 10 rankings in overall scores, indicating that current investments in health research are significantly different from those estimated to be the most effective in reducing the global burden of diarrhoeal disease by 2015

A retrospective inquiry into selected experiences of beginning teachers : a study in teacher socialization

Research attention is focused on the cultural expectations associated with the role of teacher as these expectations help shape a beginning teacher's sense of the role and of professional identity. The traditional social science quantitative research approach is contrasted with a qualitative phenomenological research perspective; the former helps reveal aggregate teacher role characteristics while the latter provides for an in-depth examination of the individual teacher's accommodation to the new role. Four experienced secondary school teachers were asked to reflect on their perception of their beginning teaching experience as it affected their sense of self as teacher. The interviews were analyzed using a participant-hermeneutic approach to reveal the emergent themes and issues of these teachers' socialization. The four teachers reported that they found teaching to be less fun and more work than they had expected; that they found minimal support from their peers; that they base their definition of good teaching on their observation of their own high school teachers; and that they generally feel powerless in the school setting