4,400 research outputs found

    Arguing Application of the Means-Plus-Function Limitation to Claim Elements Without Traditional Means Language

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    Aerial Inventories of Waterfowl in Illinois and Estimation of Moist-soil Plant Seed Abundance for Waterfowl on Lands Managed by Illinois Department of Natural Resources

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    Grant/Contract No: W-43-R 53-54-55Reports on progress and results of inventories of waterfowl along the Illinois and central Mississippi rivers during fall and winter and estimation of moist-soil plant seed abundance for waterfowl on lands managed by Illinois Department of Natural ResourcesINHS Technical Report Prepared for U.S. Fish & Wildlife Service, Illinois Department of Natural Resource

    A Likelihood Ratio Test for Changes in Homeolog Expression Bias

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    Background Gene duplications are a major source of raw material for evolution and a likely contributor to the diversity of life on earth. Duplicate genes (i.e., homeologs, in the case of a whole genome duplication) may retain their ancestral function, sub- or neofunctionalize, or be lost entirely. A primary way that duplicate genes evolve new functions is by altering their expression patterns. Comparing the expression patterns of duplicate genes gives clues as to whether any of these evolutionary processes have occurred. Results We develop a likelihood ratio test for the analysis of the expression ratios of duplicate genes across two conditions (e.g., tissues). We demonstrate an application of this test by comparing homeolog expression patterns of 1448 homeologous gene pairs using RNA-seq data generated from leaves and petals of an allotetraploid monkeyflower (Mimulus luteus). We assess the sensitivity of this test to different levels of homeolog expression bias and compare the method to several alternatives. Conclusions The likelihood ratio test derived here is a direct, transparent, and easily implemented method for detecting changes in homeolog expression bias that outperforms alternative approaches. While our method was derived with homeolog analysis in mind, this method can be used to analyze changes in the ratio of expression levels between any two genes in any two conditions

    The Effects of Repetitive Drop Jumps on Impact Phase Joint Kinematics and Kinetics

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    The purpose of the study was to investigate the effects of fatigue on lower extremity joint kinematics, and kinetics during repetitive drop jumps. Twelve recreationally active males (n = 6) and females (n = 6) (nine used for analysis) performed repetitive drop jumps until they could no longer reach 80% of their initial drop jump height. Kinematic and kinetic variables were assessed during the impact phase (100 ms) of all jumps. Fatigued landings were performed with increased knee extension, and ankle plantar flexion at initial contact, as well as increased ankle range of motion during the impact phase. Fatigue also resulted in increased peak ankle power absorption and increased energy absorption at the ankle. This was accompanied by an approximately equal reduction in energy absorption at the knee. While the knee extensors were the muscle group primarily responsible for absorbing the impact, individuals compensated for increased knee extension when fatigued by an increased use of the ankle plantar flexors to help absorb the forces during impact. Thus, as fatigue set in and individuals landed with more extended lower extremities, they adopted a landing strategy that shifted a greater burden to the ankle for absorbing the kinetic energy of the impact

    Positive airway pressure ventilation and complications in pediatric tracheocutaneous fistula repair

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152684/1/lary27834_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/152684/2/lary27834.pd

    More than Access: The Role of Support Services in the Transitional Experiences of Underrepresented Students in a Statewide Access Program

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    While a number of studies have examined outcomes associated with early intervention programs that have a financial aid component, few have examined the experiences of student beneficiaries of those programs and the administrators charged with carrying out state mandates associated with the implementation of the programs. This gap in the literature exists for students and administrators at both the K-12 and higher education institution levels. This qualitative study reports findings from interviews and focus groups with 76 administrators and 150 students from colleges and universities in a Midwestern state that implemented a middle school-to-college access program. Findings highlight the disparity between institutional supports for students across the state, differential use of services provided, lack of clarity of financial support structures, and the resulting difficulties encountered by students in the program and the staff hired to administer the program

    Coherent Cancellation of Photothermal Noise in GaAs/Al0.92_{0.92}Ga0.08_{0.08}As Bragg Mirrors

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    Thermal noise is a limiting factor in many high-precision optical experiments. A search is underway for novel optical materials with reduced thermal noise. One such pair of materials, gallium arsenide and aluminum-alloyed gallium arsenide (collectively referred to as AlGaAs), shows promise for its low Brownian noise when compared to conventional materials such as silica and tantala. However, AlGaAs has the potential to produce a high level of thermo-optic noise. We have fabricated a set of AlGaAs crystalline coatings, transferred to fused silica substrates, whose layer structure has been optimized to reduce thermo-optic noise by inducing coherent cancellation of the thermoelastic and thermorefractive effects. By measuring the photothermal transfer function of these mirrors, we find evidence that this optimization has been successful.Comment: 10 pages, 7 figure
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