Experimentally Determined Structure of the Shock Reflection Process in Ionizing Xenon

The results of an experimental investigation of the reflection of strong shocks in xenon from the end wall of a shock tube are presented. The reflection of the incident shock structure, consisting of a frozen shock front, a region of relatively uniform frozen flow, and an ionization front, was observed with a fast‐rise (0.3 μsec) pressure gauge mounted in the shock‐tube end wall. The incident shock Mach number was varied from 11‐20, and the initial pressure was varied from 0.1‐1.5mmHg. The interaction between the reflecting shock and the ionizing gas in the incident shock structure produces a complicated series of shock and rarefaction waves; those waves that propagate back to the end wall were observed with the pressure gauge. A simple model which includes the gross features of the shock reflection process is used to calculate end wall pressures. The calculated pressures agree well with the experimental observations. In addition, ionization relaxation times for xenon behind the incident and reflected shocks are presented. The relaxation time data yield a better understanding of the ionization relaxation process in monatomic gases and provide an estimate for the electron‐atom, inelastic cross section for xenon

Measurements of test time in the GALCIT 17-inch shock tube

Experimental measurements of test time were obtained in the GALCIT 17-in. shock tube using both air and argon for driven gases. One series of tests was conducted using a constant driver pressure (pure helium) for various initial pressures of the driven gases. Another series was conducted using air for the driven gas at various initial pressures holding the shock Mach number constant. The data are presented and compared to theoretical predictions computed from the theory in two recent papers by Mirels for the case of a laminar and turbulent wall boundary layer

Experimentally Determined Structure of the Shock Reflection Process in Ionizing Xenon

The results of an experimental investigation of the reflection of strong shocks in xenon from the end wall of a shock tube are presented. The reflection of the incident shock structure, consisting of a frozen shock front, a region of relatively uniform frozen flow, and an ionization front, was observed with a fast‐rise (0.3 μsec) pressure gauge mounted in the shock‐tube end wall. The incident shock Mach number was varied from 11‐20, and the initial pressure was varied from 0.1‐1.5mmHg. The interaction between the reflecting shock and the ionizing gas in the incident shock structure produces a complicated series of shock and rarefaction waves; those waves that propagate back to the end wall were observed with the pressure gauge. A simple model which includes the gross features of the shock reflection process is used to calculate end wall pressures. The calculated pressures agree well with the experimental observations. In addition, ionization relaxation times for xenon behind the incident and reflected shocks are presented. The relaxation time data yield a better understanding of the ionization relaxation process in monatomic gases and provide an estimate for the electron‐atom, inelastic cross section for xenon

Chandra Detections of Two Quiescent Black Hole X-Ray Transients

Using the Chandra X-ray Observatory, we have detected the black hole transients V4641 Sgr and XTE J1859+226 in their low luminosity, quiescent states. The 0.3-8 keV luminosities are (4.0^(+3.3)_(-2.4))E31 (d/7 kpc)^2 erg/s and (4.2^(+4.8)_(-2.2))E31 (d/11 kpc)^2 erg/s for V4641 Sgr and XTE J1859+226, respectively. With the addition of these 2 systems, 14 out of the 15 transients with confirmed black holes (via compact object mass measurements) now have measured quiescent luminosities or sensitive upper limits. The only exception is GRS 1915+105, which has not been in quiescence since its discovery in 1992. The luminosities for V4641 Sgr and XTE J1859+226 are consistent with the median luminosity of 2E31 erg/s for the systems with previous detections. Our analysis suggests that the quiescent X-ray spectrum of V4641 Sgr is harder than for the other systems in this group, but, due to the low statistical quality of the spectrum, it is not clear if V4641 Sgr is intrinsically hard or if the column density is higher than the interstellar value. Focusing on V4641 Sgr, we compare our results to theoretical models for X-ray emission from black holes in quiescence. Also, we obtain precise X-ray positions for V4641 Sgr and XTE J1859+226 via cross-correlation of the X-ray sources detected near our targets with IR sources in the 2 Micron All-Sky Survey catalog.Comment: 4 pages, Accepted by ApJ Letter

HIV-free survival and morbidity among formula-fed infants in a prevention of mother-to-child transmission of HIV program in rural Haiti

<p>Abstract</p> <p>Background</p> <p>Partners In Health (PIH) works with the Ministry of Health to provide comprehensive health services in Haiti. Between 1994 and 2009, PIH recommended exclusive formula feeding in the prevention of mother-to-child transmission (PMTCT) of HIV program and provided support to implement this strategy. We conducted this study to assess HIV-free survival and prevalence of diarrhea and malnutrition among infants in our PMTCT program in rural Haiti where exclusive formula feeding was supported.</p> <p>Methods</p> <p>We reviewed medical charts of PMTCT mother-infant pairs at PIH between November 2004 and August 2006 through a retrospective longitudinal study and cross-sectional survey. We performed household surveys for each pair and at control households matched by infant's age and gender.</p> <p>Results</p> <p>254 mother-infant pairs were included. 15.3% of infants were low birth weight; most births occurred at home (68.8%). 55.9% of households had no latrine; food insecurity was high (mean score of 18; scale 0-27, SD = 5.3). HIV-free survival at 18 months was 90.6%. Within the cohort, 9 children (3.5%) were HIV-infected and 17 (6.7%) died. Community controls were more likely to be breastfed (P = 0.003) and more likely to introduce food early (P = 0.003) than PMTCT-program households. There was no difference in moderate malnutrition (Z score ≤ 2 SD) between PMTCT and community groups after controlling for guardian's education, marital status, and food insecurity (OR = 1.05; 95% CI: 0.67, 1.64; P = 0.84). Diarrhea was 2.9 times more prevalent among community children than PMTCT infants (30.3% vs. 12.2%; P < 0.0001).</p> <p>Conclusions</p> <p>In a PIH-supported program in rural Haiti that addressed socioeconomic barriers to ill-health, breast milk substitution was safe, acceptable and feasible for PMTCT for HIV-infected women choosing this option.</p

Quasiparticle Effective Mass for the Two- and Three-Dimensional Electron Gas

We calculate the quasiparticle effective mass for the electron gas in two and three dimensions in the metallic region. We employ the single particle scattering potential coming from the Sj\"{o}lander-Stott theory and enforce the Friedel sum rule by adjusting the effective electron mass in a scattering calculation. In 3D our effective mass is a monotonically decreasing function of $r_s$ throughout the whole metallic domain, as implied by the most recent numerical results. In 2D we obtain reasonable agreement with the experimental data, as well as with other calculations based on the Fermi liquid theory. We also present results of a variety of different treatments for the effective mass in 2D and 3D.Comment: 12 pages, 2 figure

Data Availability Principles and Practice

publishedVersio

Localizing INTEGRAL Sources with Chandra: X-Ray and Multi-Wavelength Identifications and Energy Spectra

We report on Chandra observations of 18 hard X-ray (>20 keV) sources discovered with the INTEGRAL satellite near the Galactic plane. For 14 of the INTEGRAL sources, we have uncovered one or two potential Chandra counterparts per source. These provide soft X-ray (0.3-10 keV) spectra and sub-arcsecond localizations, which we use to identify counterparts at other wavelengths, providing information about the nature of each source. Despite the fact that all of the sources are within 5 degrees of the plane, four of the IGR sources are AGN (IGR J01545+6437, IGR J15391-5307, IGR J15415-5029, and IGR J21565+5948) and four others are likely AGN (IGR J03103+5706, IGR J09189-4418, IGR J16413-4046, and IGR J16560-4958) based on each of them having a strong IR excess and/or extended optical or near-IR emission. We compare the X-ray and near-IR fluxes of this group of sources to those of AGN selected by their 2-10 keV emission in previous studies and find that these IGR AGN are in the range of typical values. There is evidence in favor of four of the sources being Galactic (IGR J12489-6243, IGR J15293-5609, IGR J16173-5023, and IGR J16206-5253), but only IGR J15293-5609 is confirmed as a Galactic source as it has a unique Chandra counterpart and a parallax measurement from previous optical observations that puts its distance at 1.56+/-0.12 kpc. The 0.3-10 keV luminosity for this source is 1.4e32 erg/s, and its optical/IR spectral energy distribution is well described by a blackbody with a temperature of 4200-7000 K and a radius of 12.0-16.4 Rsun. These values suggest that IGR J15293-5609 is a symbiotic binary with an early K-type giant and a white dwarf accretor. We also obtained likely Chandra identifications for IGR J13402-6428 and IGR J15368-5102, but follow-up observations are required to constrain their source types.Comment: 17 pages, accepted by Ap

Quantifying Drug-Induced Bone Marrow Toxicity Using a Novel Haematopoiesis Systems Pharmacology Model.

Haematological toxicity associated with cancer therapeutics is monitored by changes in blood cell count, and their primary effect is on proliferative progenitors in the bone marrow. Using observations in rat bone marrow and blood, we characterize a mathematical model that comprises cell proliferation and differentiation of the full haematopoietic phylogeny, with interacting feedback loops between lineages in homeostasis as well as following carboplatin exposure. We accurately predicted the temporal dynamics of several mature cell types related to carboplatin-induced bone marrow toxicity and identified novel insights into haematopoiesis. Our model confirms a significant degree of plasticity within bone marrow cells, with the number and type of both early progenitors and circulating cells affecting cell balance, via feedback mechanisms, through fate decisions of the multipotent progenitors. We also demonstrated cross-species translation of our predictions to patients, applying the same core model structure and considering differences in drug-dependent and physiology-dependent parameters