17,002 research outputs found

    The Admission of DNA Evidence in State and Federal Courts

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    Variable-camber systems integration and operational performance of the AFTI/F-111 mission adaptive wing

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    The advanced fighter technology integration, the AFTI/F-111 aircraft, is a preproduction F-111A testbed research airplane that was fitted with a smooth variable-camber mission adaptive wing. The camber was positioned and controlled by flexing the upper skins through rotary actuators and linkages driven by power drive units. The wing camber and control system are described. The measured servoactuator frequency responses are presented along with analytical predictions derived from the integrated characteristics of the control elements. A mission adaptive wing system chronology is used to illustrate and assess the reliability and dependability of the servoactuator system during 1524 hours of ground tests and 145 hours of flight testing

    A community pharmacy weight management programme: an evaluation of effectiveness

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    <p>Background: Community pharmacies may offer an accessible way of delivering weight-management programmes but there have been few trials that use clinically significant weight loss outcomes, objective measures of weight and follow-up to 12 months. We aimed to evaluate weight change among patients who used the Counterweight weight management programme delivered by community pharmacies.</p> <p>Methods: The Counterweight Programme was introduced into community pharmacies in Fife, Scotland in 2009 for patients with a BMI ≥ 30 kg/m2 or a BMI ≥ 28 kg/m2 with a co-morbidity in localities in which Counterweight was not available at GP practices. The aim was to achieve an energy deficit of 500-600 kcal per day. Counterweight specialist dietitians delivered training, support and patient information materials to community pharmacies. Patient weight was measured by pharmacy staff at each weight management session. Weight data recorded at each weight management session were used to estimate weight change and attendance at 3, 6 and 12 months.</p> <p>Results: Between March 2009 and July 2012, 458 patients were enrolled by the community pharmacies. Three-quarters of patients were women, mean age was 54 (SD 7.4) years and mean BMI 36.1 (SD 5.9) kg/m2. Of 314 patients enrolled for at least 12 months, 32 (10.2% on an intention to treat basis) had achieved the target weight loss of ≥5%; this was 41.6% of those who attended at 12 months representing a mean weight loss of 4.1 kg. Using Last Observation Carried Forward, 15.9% achieved the target weight loss within 12 months of enrolling. There was no significant effect of sex, baseline BMI or age on weight loss.</p> <p>Conclusions: The Counterweight pharmacy programme has a similar effectiveness to other primary care based weight management programmes and should be considered as part of a range of services available to a community to manage overweight and obesity.</p&gt

    Reducing Disparities by way of a Cancer Disparities Research Training Program

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    Background: For minority populations, there is a continuing disparity in the burden of death and illness from cancer. Research to address this disparity should be conducted by investigators who can best understand and address the needs of culturally diverse communities. However, minorities are under-represented in health-related research. The goal of this project was to develop and evaluate an approach to motivating and preparing master’s degree students for careers dedicated to cancer disparities research. Method: A Cancer Disparities Research Training Program (CDRTP) was initiated in 2010. The program consists of coursework, practicum experiences, and research opportunities. Assessment of the curriculum is based on monitoring achievement of evaluation indicators and includes a quantitative assessment and qualitative approach. Results: In its first three years, the program graduated 20 trainees, all of whom were minorities (18 African Americans and two Asians). When asked about career goals, two-thirds of the trainees indicated interest in pursuing careers in research on cancer prevention and control. The trainees expressed high satisfaction with the courses, instructor, materials, and curriculum. Although trainees had suggestions about course details, evaluations overall were positive. Across focus groups, three recurrent themes emerged regarding activities to enhance the student experience: having a wider variety of topics, more guest speakers, and field trips. Conclusion: The CDRTP was intended to recruit students – primarily African Americans – into research on prevention and control of cancer disparities. Although final evaluation of the program’s overall outcome will not be available for several years, a preliminary evaluation indicates the program is being successful

    PCN11: ECONOMIC EVALUATION OF LIPOSOMAL DOXORUBICIN VS TOPOTECAN FOR RECURRENT OVARIAN CANCER IN THE UK

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    Topology of Neutral Hydrogen Within the Small Magellanic Cloud

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    In this paper, genus statistics have been applied to an HI column density map of the Small Magellanic Cloud in order to study its topology. To learn how topology changes with the scale of the system, we provide the study of topology for column density maps at varying resolution. To evaluate the statistical error of the genus we randomly reassign the phases of the Fourier modes while keeping the amplitudes. We find, that at the smallest scales studied (40pc≤λ≤80pc40 {pc}\leq\lambda\leq 80 {pc}) the genus shift is in all regions negative, implying a clump topology. At the larger scales (110pc≤λ≤250pc110 {pc}\leq\lambda\leq 250 {pc}) the topology shift is detected to be negative in 4 cases and positive (``swiss cheese'' topology) in 2 cases. In 4 regions there is no statistically significant topology shift at large scales

    Research on Long-Term Care Homes for Older People in Brazil: Protocol for Scoping Review

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    LOTUS CONSORTIUM - Improving care in Long-term Care Institutions in Brazil and Europe through Collaboration and ResearchBackground The fast growth of the ageing population in low and middle-income countries, such as Brazil, has allowed little time for social and health care systems to adapt. As the care needs for the most vulnerable and frail older people become increasingly complex, services and governments need to ensure that long term care homes deliver high-quality and evidence-based care to meet their healthcare needs. Aim To examine and map the range of research undertaken in Brazil regarding care homes published in peer reviewed journals. Method This scoping review will consider all relevant peer-reviewed primary studies fully or partly conducted in Brazilian care homes including those which consider workforce (for example, e.g. healthcare professionals, care staff, and management level staff) and care home residents (older people aged 60 years and above), using empirical and original research focused on any health related topic. The searches will be conducted using bibliographic databases (MEDLINE, EMBASE, LILACS and Google Scholar) and manual searching of the reference lists of relevant studies published in English, Portuguese or Spanish from inception up to 2018. Two authors will independently screen each document by title and abstract against the eligibility criteria. In case of disagreement, a third reviewer will be consulted. Data from the included studies will be extracted and reported using tables, graphs, and narrative accounts using elements of content analysis. The Mixed Methods Appraisal Tool will be used to appraise the methodological quality of the included studies

    Deep Well Pump Seal

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    Lifewater International, a Christian non-profit, trains locals to repair water well hand pumps in various third world countries. It would be beneficial to retrofit difficult-to-repair hand pumps with a locally-made pump cylinder such as HydroMission\u27s SlapShot . The majority of the components in the SlapShot can be easily obtained in rural third world villages. However, the thick leather gaskets required to seal the water cylinder during the pumping operation are imported. These thick leather gaskets are expensive, and when they fail, this results in pumps being out of commission for extended periods of time. Lifewater has presented this problem to a team of three undergraduate mechanical engineering students at California Polytechnic State University, San Luis Obispo with the goal of being able to locally source and manufacture an adequate seal to replace the current thick leather seal
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