Концепт любов в іспаномовній Біблії: лінгвокультурологічний аспект (The concept love in the Spanish Bible: linguocultural aspect)

Стаття пов’язана з проблемою текстового втілення концепту ЛЮБОВ в іспаномовній Біблії. Сформульовано теоретичні засади дослідження концепту ЛЮБОВ у біблійному тексті. Розроблено методику дослідження концепту ЛЮБОВ. Окреслено вербальну репрезентацію концепту ЛЮБОВ у картині світу носіїв іспанської мови. Визначено етнокультурну специфіку засобів репрезентації концепту ЛЮБОВ в іспаномовному тексті Біблії. (The article is connected with the problem of textual embodiment of the concept LOVE in the Spanish Bible. Is defined theoretical background of the concepts study in the Bible text. A complex methodology for the analysis of the concept Love has been elaborated. The verbal representation of the concept is revealed in the world view of native speakers of Spanish. The ethnic and cultural specificity of representation means of the concept Love in the Spanish Bible has been determined.

2007 Rideshare Workshop Launch Services Program

No abstract availabl

ELaNa - Educational Launch of Nanosatellite Providing Routine RideShare Opportunities

Since the creation of the NASA CubeSat Launch Initiative (NCSLI), the need for CubeSat rideshares has dramatically increased. After only three releases of the initiative, a total of 66 CubeSats now await launch opportunities. So, how is this challenge being resolved? NASA's Launch Services Program (LSP) has studied how to integrate PPODs on Athena, Atlas V, and Delta IV launch vehicles and has been instrumental in developing several carrier systems to support CubeSats as rideshares on NASA missions. In support of the first two ELaNa missions the Poly-Picosatellite Orbital Deployer (P-POD) was adapted for use on a Taurus XL (ELaNa I) and a Delta n (ELaNa III). Four P-PODs, which contained a total eight CubeSats, were used on these first ELaNa missions. Next up is ELaNa VI, which will launch on an Atlas V in August 2012. The four ELaNa VI CubeSats, in three P-PODs, are awaiting launch, having been integrated in the NPSCuLite. To increase rideshare capabilities, the Launch Services Program (LSP) is working to integrate P-PODs on Falcon 9 missions. The proposed Falcon 9 manifest will provide greater opportunities for the CubeSat community. For years, the standard CubeSat size was 1 U to 3U. As the desire to include more science in each cube grows, so does the standard CubeSat size. No longer is a 1 U, 1.5U, 2U or 3U CubeSat the only option available; the new CubeSat standard will include 6U and possibly even 12U. With each increase in CubeSat size, the CubeSat community is pushing the capability of the current P-POD design. Not only is the carrier system affected, but integration to the Launch Vehicle is also a concern. The development of a system to accommodate not only the 3U P-POD but also carriers for larger CubeSats is ongoing. LSP considers payloads in the lkg to 180 kg range rideshare or small/secondary payloads. As new and emerging small payloads are developed, rideshare opportunities and carrier systems need to be identified and secured. The development of a rideshare carrier system is not always cost effective. Sometimes a launch vehicle with an excellent performance record appears to be a great rideshare candidate however, after completing a feasibility study, LSP may determine that the cost of the rideshare carrier system is too great and, due to budget constraints, the development cannot go forward. With the current budget environment, one cost effective way to secure rideshare opportunities is to look for synergy with other government organizations that share the same interest

ФУНКЦІОНАЛЬНІ ОСОБЛИВОСТІ ОБРАЗНОЇ СИСТЕМИ ІСПАНСЬКОЇ КАЗКИ (Functional peculiarities of the figurative system of Spanish tale)

У статті розкриваються закономірності образної системи іспанської казки як комунікативно-прагматичного репрезентанта іспанської ментальності. (The article deals with the investigation of figurative system of Spanish tale as a communicative and pragmatic representation of Spanish mentality.

Motorische Funktion nach Schlaganfall: Erkenntnisse aus verfeinerter Bewegungsanalyse und serotonerger Neuromodulation

Upper limb deficits remain a significant challenge in post-stroke motor recovery. Accurate assessment of these deficits is crucial for translating preclinical research into clinical applications. Traditional methods for quantifying recovery in animal stroke models often rely on observer scoring systems, such as manually counting eaten pellets, which lack the granular resolution needed for precise movement kinematics analysis. This thesis proposes a novel approach for refined motor recovery analysis in preclinical stroke models using machine learning methods. We developed MouseReach, an innovative toolkit that utilizes videos from a modified version of the mouse Staircase test to conduct robust movement analysis of forepaw reaching in mice. Using MouseReach, we analyzed the kinematics of post-stroke motor recovery in two widely studied animal models of ischemic stroke: photothrombosis (PT) and middle cerebral artery occlusion (MCAO). This refined analysis revealed new motor features that elucidate the differing effects of striatal and cortical stroke lesions in mice. In another set of experiments, we investigated the role of serotonergic signaling in enhancing motor recovery after stroke. Targeting the serotonergic nuclei in the brainstem, we built on evidence that serotonin upregulation significantly improves upper limb function in both animal models and humans post-stroke. By specifically activating serotonergic neurons projecting to the cervical spinal cord, we aimed to amplify the plastic reorganization of neuronal fibers. Modifying their activity resulted in substantial changes in motor function post-stroke, highlighting the delicate balance required in serotonergic signaling for maintaining coordinated movement. Additionally, serotonergic neuromodulation led to unexpected changes in mouse body temperature, revealing another physiological role of serotonin unrelated to motor function. These findings underscore the intricate role of the serotonergic system in multiple functional areas within the context of ischemic stroke and pave the way for further research aimed at improving motor deficits caused by stroke.Defizite der oberen Extremitäten bleiben eine große Herausforderung bei der motorischen Erholung nach einem Schlaganfall. Eine genaue Beurteilung dieser Defizite ist entscheidend für die Übertragung präklinischer Forschung in klinische Anwendungen. Traditionelle Methoden zur Quantifizierung der Erholung in Tiermodellen für Schlaganfälle stützen sich oft auf Beobachter-Bewertungssysteme wie das manuelle Zählen von gefressenen Pellets, die jedoch die notwendige Auflösung für eine präzise Analyse der Bewegungskinematik vermissen lassen. Diese Arbeit schlägt einen neuen Ansatz zur Analyse der motorischen Erholung in präklinischen Schlaganfallmodellen mithilfe maschinellen Lernens vor. Wir haben MouseReach entwickelt, ein innovatives Toolkit, das Videos aus einer modifizierten Version des Staircase-Tests nutzt, um die Bewegungsanalyse des Greifens mit der Vorderpfote bei Mäusen durchzuführen. Mit MouseReach haben wir die Kinematik der motorischen Erholung nach einem Schlaganfall in zwei Tiermodellen analysiert: Photothrombose (PT) und Mittlere Hirnarterienokklusion (MCAO). Diese verfeinerte Analyse offenbarte neue motorische Merkmale, die die unterschiedlichen Auswirkungen von striatalen und kortikalen Schlaganfallläsionen bei Mäusen verdeutlichen. In weiteren Experimenten haben wir die Rolle der serotonergen Signalübertragung bei der motorischen Erholung nach einem Schlaganfall untersucht. Durch das Anvisieren der serotonergen Kerne im Hirnstamm bauten wir auf Beweisen auf, dass eine Serotoninaufregulation die Funktion der oberen Extremitäten sowohl bei Tiermodellen als auch bei Menschen nach einem Schlaganfall verbessert. Durch die spezifische Aktivierung serotonerger Neuronen, die zum zervikalen Rückenmark projizieren, zielten wir darauf ab, die plastische Reorganisation von Nervenfasern zu verstärken. Dies führte zu erheblichen Veränderungen der motorischen Funktion und hob das empfindliche Gleichgewicht hervor, das in der serotonergen Signalübertragung erforderlich ist, um koordinierte Bewegungen aufrechtzuerhalten. Darüber hinaus führte die serotonerge Neuromodulation zu unerwarteten Veränderungen der Körpertemperatur von Mäusen und offenbarte eine weitere physiologische Rolle des Serotonins, die nicht mit der motorischen Funktion zusammenhängt. Diese Erkenntnisse unterstreichen die komplexe Rolle des serotonergen Systems im Kontext des ischämischen Schlaganfalls und ebnen den Weg für weitere Forschungen zur Verbesserung motorischer Defizite nach Schlaganfall

Mycotoxin Production on Water Damaged Building Materials

Due to the increased occurrence of flooding, biological by-products such as mycotoxins can cause serious health problems for homeowners. This study used two species of fungi, Aspergillus fumigatus and Stachybotrys chartarum, which have been found within homes after flooding events. Two distinct types of mycotoxins can be produced; gliotoxin by A. fumigatus and trichothecenes by S. chartarum. A preliminary study evaluated four wall materials separately, for mycotoxin production and validation of techniques. Based on these results, the experimental study built replicated interior walls of gypsum wallboard, fiberglass batt insulation, wood stud, and oriented strand board; placed the walls in mold chambers on concrete pavers; flooded and drained the walls; and exposed these walls to S. chartarum for 65 days. All four building materials showed some level of mycotoxin present on all collection days. Gypsum wallboard and fiberglass batt insulation had the highest levels of trichothecenes and levels increased over time. The wood stud and oriented strand board also contained mycotoxins, but levels did not change over time. DNA concentrations were significantly higher on the batt insulation compared to wood products. However, DNA concentrations did not directly correlate to mycotoxin levels. These results support the removal of the batt insulation and gypsum wallboard from a home if a flooding event should occur. The finding of the mycotoxin on the wood products requires further research to better understand the mycotoxin’s properties on wood in order to ensure the safety of homeowners

Kodiak Star – The Mission, the Challenges, the Success: A Look at Lesson’s Learned from the First Orbital Flight from Alaska

The Kodiak Star was a fast paced mission utilizing a number of first flight items including a payload upper deck, a light band separation system, and a method of deploying multiple payloads from the launch vehicle. The total integration time for this mission was 10-months from a novel remote launch complex. The mission configuration consisted of three Air force Payloads (PICOSat, PCSat, Sapphire) and one NASA sponsored payload, Starshine 3. On September 29, 2001, at 6.40p.m. ADT the Kodiak Star mission successfully lifted off from the Kodiak Launch Complex and 2-hours and 40 minutes later, the complete complement of spacecraft successfully separated. The success of this mission is attributed to teamwork amongst multinational groups, early identification and resolution to problems, and focus on a goal of launching the Kodiak Star in a minimum time frame, 10 months

Fungal Communities on Flooded Building Materials

Flood waters will penetrate the wall cavities of a home and the wall materials then serve as a substrate for mold development. This study measured the effect of flooding and subsequent drying on the extent and type of mold on different residential wall materials. Wet and dry wall samples were analyzed by cloning and sequencing and twenty-one mold species were identified from above and below the water line. Real-time PCR quantitated selected species on fiberglass batt insulation, gypsum wallboard, wood stud, plywood panels, vinyl siding, and house wrap. The mold species found in the highest concentration were Aspergillus fumigatus, Paecilomyces variotii, Chaetomium globosum, and Stachybotrys chartarum. The batt insulation supported the highest concentration of mold, followed by the wood stud, sheathing and gypsum wallboard. The high level of Aspergillus fumigatus and Stachybotrys chartarum on the wall materials seven months after flooding is a cause for concern

Mycotoxin Production on Water Damaged Building Materials

Due to the increased occurrence of flooding, biological by-products such as mycotoxins can cause serious health problems for homeowners. This study used two species of fungi, Aspergillus fumigatus and Stachybotrys chartarum, which have been found within homes after flooding events. Two distinct types of mycotoxins can be produced; gliotoxin by A. fumigatus and trichothecenes by S. chartarum. A preliminary study evaluated four wall materials separately, for mycotoxin production and validation of techniques. Based on these results, the experimental study built replicated interior walls of gypsum wallboard, fiberglass batt insulation, wood stud, and oriented strand board; placed the walls in mold chambers on concrete pavers; flooded and drained the walls; and exposed these walls to S. chartarum for 65 days. All four building materials showed some level of mycotoxin present on all collection days. Gypsum wallboard and fiberglass batt insulation had the highest levels of trichothecenes and levels increased over time. The wood stud and oriented strand board also contained mycotoxins, but levels did not change over time. DNA concentrations were significantly higher on the batt insulation compared to wood products. However, DNA concentrations did not directly correlate to mycotoxin levels. These results support the removal of the batt insulation and gypsum wallboard from a home if a flooding event should occur. The finding of the mycotoxin on the wood products requires further research to better understand the mycotoxin’s properties on wood in order to ensure the safety of homeowners

Fungal Communities on Flooded Building Materials

Flood waters will penetrate the wall cavities of a home and the wall materials then serve as a substrate for mold development. This study measured the effect of flooding and subsequent drying on the extent and type of mold on different residential wall materials. Wet and dry wall samples were analyzed by cloning and sequencing and twenty-one mold species were identified from above and below the water line. Real-time PCR quantitated selected species on fiberglass batt insulation, gypsum wallboard, wood stud, plywood panels, vinyl siding, and house wrap. The mold species found in the highest concentration were Aspergillus fumigatus, Paecilomyces variotii, Chaetomium globosum, and Stachybotrys chartarum. The batt insulation supported the highest concentration of mold, followed by the wood stud, sheathing and gypsum wallboard. The high level of Aspergillus fumigatus and Stachybotrys chartarum on the wall materials seven months after flooding is a cause for concern