11,179 research outputs found

    Direct UV observations of the circumstellar envelope of alpha Orionis

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    Observations were made in the IUE LWP camera, low dispersion mode, with alpha Ori being offset various distances from the center of the Long Wavelength Large Aperture along its major axis. Signal was acquired at all offset positions and is comprised of unequal components of background/dark counts, telescope-scattered light, and scattered light emanating from the extended circumstellar shell. The star is known from optical and infrared observations to possess an extended, arc-minute sized, shell of cool material. Attempts to observe this shell with the IUE are described, although the deconvolution of the stellar signal from the telescope scattered light requires further calibration effort

    Very High Resolution Solar X-ray Imaging Using Diffractive Optics

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    This paper describes the development of X-ray diffractive optics for imaging solar flares with better than 0.1 arcsec angular resolution. X-ray images with this resolution of the \geq10 MK plasma in solar active regions and solar flares would allow the cross-sectional area of magnetic loops to be resolved and the coronal flare energy release region itself to be probed. The objective of this work is to obtain X-ray images in the iron-line complex at 6.7 keV observed during solar flares with an angular resolution as fine as 0.1 arcsec - over an order of magnitude finer than is now possible. This line emission is from highly ionized iron atoms, primarily Fe xxv, in the hottest flare plasma at temperatures in excess of \approx10 MK. It provides information on the flare morphology, the iron abundance, and the distribution of the hot plasma. Studying how this plasma is heated to such high temperatures in such short times during solar flares is of critical importance in understanding these powerful transient events, one of the major objectives of solar physics. We describe the design, fabrication, and testing of phase zone plate X-ray lenses with focal lengths of \approx100 m at these energies that would be capable of achieving these objectives. We show how such lenses could be included on a two-spacecraft formation-flying mission with the lenses on the spacecraft closest to the Sun and an X-ray imaging array on the second spacecraft in the focal plane \approx100 m away. High resolution X-ray images could be obtained when the two spacecraft are aligned with the region of interest on the Sun. Requirements and constraints for the control of the two spacecraft are discussed together with the overall feasibility of such a formation-flying mission

    Hydrogen and muonium in diamond: A path-integral molecular dynamics simulation

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    Isolated hydrogen, deuterium, and muonium in diamond have been studied by path-integral molecular dynamics simulations in the canonical ensemble. Finite-temperature properties of these point defects were analyzed in the range from 100 to 800 K. Interatomic interactions were modeled by a tight-binding potential fitted to density-functional calculations. The most stable position for these hydrogenic impurities is found at the C-C bond center. Vibrational frequencies have been obtained from a linear-response approach, based on correlations of atom displacements at finite temperatures. The results show a large anharmonic effect in impurity vibrations at the bond center site, which hardens the vibrational modes with respect to a harmonic approximation. Zero-point motion causes an appreciable shift of the defect level in the electronic gap, as a consequence of electron-phonon interaction. This defect level goes down by 70 meV when replacing hydrogen by muonium.Comment: 11 pages, 8 figure

    Graphitization of small carbonate samples for paleoceanographic research at the godwin radiocarbon laboratory, University of Cambridge

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    AbstractA new radiocarbon preparation facility was set up in 2010 at the Godwin Laboratory for Palaeoclimate Research, at the University of Cambridge. Samples are graphitized via hydrogen reduction on an iron powder catalyst before being sent to the Chrono Centre, Belfast, or the Australian National University for accelerator mass spectrometry (AMS) analysis. The experimental setup and procedure have recently been developed to investigate the potential for running small samples of foraminiferal carbonate. By analyzing background values of samples ranging from 0.04 to 0.6 mg C along with similar sized secondary standards, the setup and experimental procedures were optimized for small samples. “Background” modern 14C contamination has been minimized through careful selection of iron powder, and graphitization has been optimized through the use of “small volume” reactors, allowing samples containing as little as 0.08 mg C to be graphitized and accurately dated. Graphitization efficiency/fractionation is found not to be the main limitation on the analysis of samples smaller than 0.07 mg C, which rather depends primarily on AMS ion beam optics, suggesting further improvements in small sample analysis might yet be achieved with our methodology.We would like to thank James Rolfe for running the stable isotope measurements, as well as the Royal Society and NERC grant NE/L006421/1 for research support.This is the author accepted manuscript. The final version is available from Cambridge University Press via http://dx.doi.org/10.1017/RDC.2015.

    A Single Circumbinary Disk in the HD 98800 Quadruple System

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    We present sub-arcsecond thermal infrared imaging of HD 98800, a young quadruple system composed of a pair of low-mass spectroscopic binaries separated by 0.8'' (38 AU), each with a K-dwarf primary. Images at wavelengths ranging from 5 to 24.5 microns show unequivocally that the optically fainter binary, HD 98800B, is the sole source of a comparatively large infrared excess upon which a silicate emission feature is superposed. The excess is detected only at wavelengths of 7.9 microns and longer, peaks at 25 microns, and has a best-fit black-body temperature of 150 K, indicating that most of the dust lies at distances greater than the orbital separation of the spectroscopic binary. We estimate the radial extent of the dust with a disk model that approximates radiation from the spectroscopic binary as a single source of equivalent luminosity. Given the data, the most-likely values of disk properties in the ranges considered are R_in = 5.0 +/- 2.5 AU, DeltaR = 13+/-8 AU, lambda_0 = 2(+4/-1.5) microns, gamma = 0+/-2.5, and sigma_total = 16+/-3 AU^2, where R_in is the inner radius, DeltaR is the radial extent of the disk, lambda_0 is the effective grain size, gamma is the radial power-law exponent of the optical depth, tau, and sigma_total is the total cross-section of the grains. The range of implied disk masses is 0.001--0.1 times that of the moon. These results show that, for a wide range of possible disk properties, a circumbinary disk is far more likely than a narrow ring.Comment: 11 page Latex manuscript with 3 postscript figures. Accepted for publication in Astrophysical Journal Letters. Postscript version of complete paper also available at http://www.hep.upenn.edu/PORG/web/papers/koerner00a.p

    Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment.

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    Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE. Therefore, a better understanding of the signals controlling migration of neutrophils as well as evaluating the role of these cells in demyelination is important to define cellular components that contribute to disease in MS patients. In this study, we examined the functional role of the chemokine CXCL1 in contributing to neuroinflammation and demyelination in EAE. Using transgenic mice in which expression of CXCL1 is under the control of a tetracycline-inducible promoter active within glial fibrillary acidic protein-positive cells, we have shown that sustained CXCL1 expression within the CNS increased the severity of clinical and histologic disease that was independent of an increase in the frequency of encephalitogenic Th1 and Th17 cells. Rather, disease was associated with enhanced recruitment of CD11b+ Ly6G+ neutrophils into the spinal cord. Targeting neutrophils resulted in a reduction in demyelination arguing for a role for these cells in myelin damage. Collectively, these findings emphasize that CXCL1-mediated attraction of neutrophils into the CNS augments demyelination suggesting that this signaling pathway may offer new targets for therapeutic intervention

    Exploring patterns of error in acute care using framework analysis

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    Background: Junior doctors are often the first responders to deteriorating patients in hospital. In the high-stakes and time-pressured context of acute care, the propensity for error is high. This study aimed to identify the main subject areas in which junior doctors' acute care errors occur, and cross-reference the errors with Reason's Generic Error Modelling System (GEMS). GEMS categorises errors according to the underlying cognitive processes, and thus provides insight into the causative factors. The overall aim of this study was to identify patterns in junior doctors' acute care errors in order to enhance understanding and guide the development of educational strategies. Methods: This observational study utilised simulated acute care scenarios involving junior doctors dealing with a range of emergencies. Scenarios and the subsequent debriefs were video-recorded. Framework analysis was used to categorise the errors according to eight inductively-developed key subject areas. Subsequently, a multi-dimensional analysis was performed which cross-referenced the key subject areas with an earlier categorisation of the same errors using GEMS. The numbers of errors in each category were used to identify patterns of error. Results: Eight key subject areas were identified; hospital systems, prioritisation, treatment, ethical principles, procedural skills, communication, situation awareness and infection control. There was a predominance of rule-based mistakes in relation to the key subject areas of hospital systems, prioritisation, treatment and ethical principles. In contrast, procedural skills, communication and situation awareness were more closely associated with skill-based slips and lapses. Knowledge-based mistakes were less frequent but occurred in relation to hospital systems and procedural skills. Conclusions: In order to improve the management of acutely unwell patients by junior doctors, medical educators must understand the causes of common errors. Adequate knowledge alone does not ensure prompt and appropriate management and referral. The teaching of acute care skills may be enhanced by encouraging medical educators to consider the range of potential error types, and their relationships to particular tasks and subjects. Rule-based mistakes may be amenable to simulation-based training, whereas skill-based slips and lapses may be reduced using strategies designed to raise awareness of the interplay between emotion, cognition and behaviour.</p
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