24 research outputs found
Preemptive analgesia application in acute appendicitis
BACKGROUND: Preemptive analgesia with infiltration of anesthetics into
surgical wounds before the incision has been shown to be effective in
various elective surgeries. Although this application can decrease the
postoperative pain, it is not known whether it is effective in surgery
with acute pain or not. AIMS: In this study, we evaluated whether the
preincisional local anesthetic application will decrease the
postoperative pain in patients undergoing appendectomy for acute
appendicitis. MATERIALS AND METHODS: Forty consecutive patients
admitted to the Emergency Department with a tentative diagnosis of
acute appendicitis were randomly divided into two groups. In Group 1,
1% prilocaine and 0.25% bupivacaine was injected to the planned
incision site cutaneously, subcutaneously, and under the fascia of the
external oblique muscle. The patients in Group 2 received the same
volume of saline to the same anatomical sites. Initially, 1 mg/kg
meperidine was administered intramuscularly to both groups for
postoperative analgesia. If needed further, meperidine 0.5 mg/kg was
administered intramuscularly. Postoperative pain was assed by visual
analog scale during the first 24 hours. The analgesic needed and the
doses required were recorded. STATISTICAL ANALYSES: All data were
stored using SPSS 11.0 for Windows. Wilcoxon test and two independent
samples T-test was used as the non-parametric test. RESULTS AND
CONCLUSIONS: No statistically significant difference was found between
the two groups' pain score, the number of patients who needed
analgesic, and the amount and the number of doses administered. In
conclusion, we think that preincisional local anesthetic infiltration
does not help to decrease the need for postoperative analgesic use in
patients with acute pain, and this may be related with previous central
sensitization
High altitude-related hypertensive crisis and acute kidney injury in an asymptomatic healthy individual
Expression of oxidative stress and antioxidant defense genes in the kidney of inbred mice after intestinal ischemia and reperfusion
Gene expression profile of oxidative stress in the lung of inbred mice after intestinal ischemia/reperfusion injury
Preemptive analgesia application in acute appendicitis
BACKGROUND: Preemptive analgesia with infiltration of anesthetics into
surgical wounds before the incision has been shown to be effective in
various elective surgeries. Although this application can decrease the
postoperative pain, it is not known whether it is effective in surgery
with acute pain or not. AIMS: In this study, we evaluated whether the
preincisional local anesthetic application will decrease the
postoperative pain in patients undergoing appendectomy for acute
appendicitis. MATERIALS AND METHODS: Forty consecutive patients
admitted to the Emergency Department with a tentative diagnosis of
acute appendicitis were randomly divided into two groups. In Group 1,
1% prilocaine and 0.25% bupivacaine was injected to the planned
incision site cutaneously, subcutaneously, and under the fascia of the
external oblique muscle. The patients in Group 2 received the same
volume of saline to the same anatomical sites. Initially, 1 mg/kg
meperidine was administered intramuscularly to both groups for
postoperative analgesia. If needed further, meperidine 0.5 mg/kg was
administered intramuscularly. Postoperative pain was assed by visual
analog scale during the first 24 hours. The analgesic needed and the
doses required were recorded. STATISTICAL ANALYSES: All data were
stored using SPSS 11.0 for Windows. Wilcoxon test and two independent
samples T-test was used as the non-parametric test. RESULTS AND
CONCLUSIONS: No statistically significant difference was found between
the two groups' pain score, the number of patients who needed
analgesic, and the amount and the number of doses administered. In
conclusion, we think that preincisional local anesthetic infiltration
does not help to decrease the need for postoperative analgesic use in
patients with acute pain, and this may be related with previous central
sensitization
The Efficiency and Duration of the Analgesic Effects of Musical Therapy on Postoperative Pain
OBJECTIVES: The aim of this study was first to find out the effect of music therapy on postoperative analgesia and second to determine the duration of its effect. METHODS: Seventy patients who were undergoing elective cesarean delivery were enrolled. The patients were randomly allocated into two groups as follows: In Group 1, patients listened to music through a headphone for one hour after surgery, while in Group 2, patients did not listen to any music during the same period. In the postanesthesia care unit, patients were connected to a Patient Controlled Analgesia (PCA) device. The PCA device (tramadol 3 mg/ml) was set to deliver a bolus of 20 mg, with a lockout interval of 15 min and 4-hour maximal dose of 150 mg. Postoperative pain was assessed with a visual analog scale (VAS) and consumption of tramadol was recorded at 4, 8, 12, 16, 20 and 24 hours. RESULTS: There was a significant decrease in Group 1 with respect to PCA delivery frequency at the 4th hour postoperatively (p\u3c0.05). Concerning the postoperative tramadol consumption, values measured at the 4th hour were significantly lower in Group 1 (p\u3c0.05). The total amount of tramadol consumption and additional analgesic use in the postoperative 24 hours were again lower in Group 1 when compared with Group 2 (p\u3c0.05). All VAS values were lower in Group 1 when compared with Group 2 (p\u3c0.05). CONCLUSION: We suggest that music therapy given after surgery decreases postoperative pain in the first 24 hours and the analgesic consumption during the first four hours
Comparison of emergence and discharge times between two Total Intravenous Anesthesia techniques: Remifentanil and Fentanylâ
Effects of the menstrual cycle on injection pain due to rocuronium
WOS: 000325732900009PubMed: 23965205Study Objective: To investigate the effect of the menstrual cycle on rocuronium injection pain. Design: Prospective, randomized, double-blinded study. Setting: Academic medical center. Patients: 80 ASA physical status 1 and 2 women scheduled for elective surgery with general anesthesia. Measurements: Patients were divided into two groups according to their time in the menstrual cycle. Forty patients at days 8 to 12 of the menstrual cycle were considered to be at the follicular phase (Group F), and 40 patients at days 20 to 24 of the menstrual cycle were considered to be at the luteal phase (Group L).Withdrawal movements were recorded. Main Results: Overall frequency of withdrawal movements was significantly higher in Group L than Group F (P < 0.001). The mean withdrawal movement score was 1.77 +/- 0.76 in Group L and 0.52 +/- 0.67 in Group F. Conclusion: Menstrual cycle phases affect the severity of rocuronium injection pain. Women exhibit greater pain sensitivity from rocuronium injection in the luteal phase than the follicular phase. (c) 2013 Elsevier Inc. All rights reserved