2,832 research outputs found

    The "handedness" of language: Directional symmetry breaking of sign usage in words

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    Language, which allows complex ideas to be communicated through symbolic sequences, is a characteristic feature of our species and manifested in a multitude of forms. Using large written corpora for many different languages and scripts, we show that the occurrence probability distributions of signs at the left and right ends of words have a distinct heterogeneous nature. Characterizing this asymmetry using quantitative inequality measures, viz. information entropy and the Gini index, we show that the beginning of a word is less restrictive in sign usage than the end. This property is not simply attributable to the use of common affixes as it is seen even when only word roots are considered. We use the existence of this asymmetry to infer the direction of writing in undeciphered inscriptions that agrees with the archaeological evidence. Unlike traditional investigations of phonotactic constraints which focus on language-specific patterns, our study reveals a property valid across languages and writing systems. As both language and writing are unique aspects of our species, this universal signature may reflect an innate feature of the human cognitive phenomenon.Comment: 10 pages, 4 figures + Supplementary Information (15 pages, 8 figures), final corrected versio

    Host Records of Lipolexis oregmae Gahan (Hymenoptera: Braconidae: Aphidiinae) with Food Plants in India (A Review Article)

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    The present review article deals the association of Lipolexis oregmae Gahan with their aphid host and their food plants for the possible use in biological control programme. Aphids are small sap sucking plant bugs and most important groups of phytophagous insect because of their polymorphism, host alternative heterocious behaviour and reproductive habits, they cause serious problems on agricultural and horticultural plants even at low densities so their management is necessary. L.oregmae Gahan is very important aphid parasitoids and widely distributed throughout the Asia and considered as an important parasitoids for the biological control programme. It has been successfully introduced in Florida and other areas. It is recorded on 19 aphid species (Aphis (Toxoptera) aurantii,  Aphis (Toxoptera) citricidus, Aphis (Toxoptera) odinae, Aphis craccivora, Aphis fabae, Aphis gossypii, Aphis nasturtii, Aphis nerii, Aphis ruborum longisetosus, Aphis solanella, Aphis spiraecola, Greenidae formosana, Liosomaphis himalayensis, Myzus avenae, Myzus (Nectarosiphon) persicae, Rhopalosiphum maidis, Rhopalosiphum nymphaeae, Sitobion avenae, Tuberolachnus salignu) in India on several specific host plants. Its maximum parasitization was recorded on Aphis gossypii infesting (23 host plants), followed by Aphis craccivora (19 host plants), Aphis nasturtii (16 host plants), Aphis spiraecola (13 host plants) and Myzus persicae (9 host plants)

    Early Results of a Modular Cementless Tibial Component for Total Knee Arthroplasty

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    Cementless components in TKA have been used for almost 3 decades, despite mixed success rates. However, biologic fixation remains attractive, especially for younger patients, because of the potential of unlimited durability. This paper is the first to report results on a modular tibial base plate using trabecular metal as a fixation surface. Twenty-four primary TKAs were evaluated clinical and radiographically at mean 1.9 year followup. Excellent clinical results were obtained. There was no significant subsidence or change in orientation of any component. One component was probably loose radiographically but was insufficiently symptomatic to warrant revision. Five components showed nonprogressive radiolucent lines. One reoperation was performed for stiffness, at which time the components were well fixed. Thus, it would appear that excellent bony fixation can be achieved with a modular cementless tibial component with excellent short-term clinical results

    Armendariz Semirings and Semicommutative Semirings

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    In this paper we study Armendariz semiring, which has been introduced by V.Gupta and P.kumar, in the paper entitled `Armendariz and qusi-Armendariz and PS-semirings' [8]. We extend some results of Armendariz rings and semi-commutative rings of [3] for semirings with 1≠01\neq0. (i)We obtain that for a semirings S, S is Armendariz if and only eS and (1+e)S are Armendariz for every idempotent e of S if and only if eS and (1+e)S are Armendariz for every central idempotent e of S. (ii) For a semiring S if S/I is an Armendariz semiring for some reduced ideal I of S then S is Armendariz

    Handover-Count based Velocity Estimation of Cellular-Connected UAVs

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    Cellular-connected unmanned aerial vehicles (UAVs) are expected to play a major role in various civilian and commercial applications in the future. While existing cellular networks can provide wireless coverage to UAV user equipment (UE), such legacy networks are optimized for ground users which makes it challenging to provide reliable connectivity to aerial UEs. To ensure reliable and effective mobility management for aerial UEs, estimating the velocity of cellular-connected UAVs carries critical importance. In this paper, we introduce an approximate probability mass function (PMF) of handover count (HOC) for different UAV velocities and different ground base station (GBS) densities. Afterward, we derive the Cramer-Rao lower bound (CRLB) for the velocity estimate of a UAV, and also provide a simple unbiased estimator for the UAV's velocity which depends on the GBS density and HOC measurement time. Our simulation results show that the accuracy of velocity estimation increases with the GBS density and HOC measurement window. Moreover, the velocity of commercially available UAVs can be estimated efficiently with reasonable accuracy.Comment: Submitted to IEEE SPAWC 2020, Atlanta, G

    Incorporating Chromatin Accessibility Data into Sequence-to-Expression Modeling

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    AbstractPrediction of gene expression levels from regulatory sequences is one of the major challenges of genomic biology today. A particularly promising approach to this problem is that taken by thermodynamics-based models that interpret an enhancer sequence in a given cellular context specified by transcription factor concentration levels and predict precise expression levels driven by that enhancer. Such models have so far not accounted for the effect of chromatin accessibility on interactions between transcription factor and DNA and consequently on gene-expression levels. Here, we extend a thermodynamics-based model of gene expression, called GEMSTAT (Gene Expression Modeling Based on Statistical Thermodynamics), to incorporate chromatin accessibility data and quantify its effect on accuracy of expression prediction. In the new model, called GEMSTAT-A, accessibility at a binding site is assumed to affect the transcription factor’s binding strength at the site, whereas all other aspects are identical to the GEMSTAT model. We show that this modification results in significantly better fits in a data set of over 30 enhancers regulating spatial expression patterns in the blastoderm-stage Drosophila embryo. It is important to note that the improved fits result not from an overall elevated accessibility in active enhancers but from the variation of accessibility levels within an enhancer. With whole-genome DNA accessibility measurements becoming increasingly popular, our work demonstrates how such data may be useful for sequence-to-expression models. It also calls for future advances in modeling accessibility levels from sequence and the transregulatory context, so as to predict accurately the effect of cis and trans perturbations on gene expression

    Break Down Resumes into Sections to Extract Data and Perform Text Analysis using Python

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    The objective of AI-based resume screening is to automate the screening process, and text, keyword, and named entity recognition extraction are critical. This paper discusses segmenting resumes in order to extract data and perform text analysis. The raw CV file has been imported, and the resume data cleaned to remove extra spaces, punctuation and stop words. To extract names from resumes, regular expressions are used. We have also used the spaCy library which is considered the most accurate natural language processing library. It includes already-trained models for entity recognition, parsing, and tagging. The experimental method is used with resume data sourced from Kaggle, and external Source (MTIS)

    Eosinophilia as Initial Presentation of Occult Malignancy

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    Eosinophilia is not an uncommon finding on a routine complete blood count (CBC) during a primary care visit. The differential diagnosis is varied including allergic/atopic disease, drug reaction, infection, inflammatory conditions, and malignancy. An 80-year-old male was incidentally found to have leukocytosis on routine labs. White blood cell (WBC) was 27.5 K/ul with eosinophilia 4.3 K/ul (normal range 0-0.6 Kul) and Hemoglobin/Platelet counts were normal. Patient was asymptomatic. Denied history of medication change or allergy. Chest X-Ray (CXR) followed by Computed tomography (CT) showed 5 cm pulmonary mass with mediastinal lymphadenopathy. Patient developed progressively enlarging left neck mass, hoarseness, weight loss and decreased appetite in the next 3 weeks. WBC increased steeply to 65 K/ul with eosinophil count - 18.5 K/ul. CT neck revealed a large heterogeneous mass of the thyroid extending to the trachea, esophagus, and mediastinum. Patient decided not to proceed with further diagnostic workup and management given his age and comorbidities. Eosinophilia can be asymptomatic or present with nonspecific symptoms like cough, fatigue, skin rash or neuropathy. Eosinophilia work up starts with a comprehensive history detailing travel history, exposure to well water/spring water, analysis of past medical history to include asthma, atopy and especially medication history. Physical exam with attention to atopy/eczema and skin rash is vital. Work up may include a CBC, peripheral blood smear, stool test (for ova and parasite), IgE/tryptase levels and evaluation for occult malignancy (CXR is an ideal first step). Further testing with Bone marrow biopsy and CT scans is a consideration if a clear diagnosis is not achieved. Life-threatening complications of untreated hyper-eosinophilia include thromboembolism, endomyocardial fibrosis, cognitive disturbances, and respiratory failure. Incidence of eosinophilia is 1% in malignant tumors. Malignancy encompasses hematological cancers (acute leukemia, chronic myeloid leukemia, systemic mastocytosis, lymphoid neoplasms) and solid tumors (lung, thyroid, breast and gastrointestinal tract cancers). Eosinophilia suggests advanced disease in solid tumors and portends poor prognosis. Paraneoplastic eosinophilia has been reported in thyroid cancer (sclerosing muco-epidermoid) and lung cancer (squamous and adenocarcinoma). Pathophysiology of eosinophilia in solid tumors is related to bone marrow stimulation through cytokines (interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-2). Primary eosinophilia responds to steroids and hydroxyurea. Treating the underlying malignancy is the cornerstone of paraneoplastic eosinophilia management. We present a case of extreme progressive eosinophilia secondary to a malignancy which would be of interest to the primary care clinician

    Biochemical characterization and Biolog based identification of efficient Jute retting bacterial isolates from retting water

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    Jute is considered as one of the cheapest natural fibre after cotton in terms of its production and uses. Retting is the most important post-harvest operation to yield high quality jute fibre and is solely carried out by various types of retting microorganisms. The present study was undertaken to screen and characterize the efficient retting microbes isolated from retting water based on their enzymatic activity followed by biolog based idenfication of those efficient microbes. These isolates were characterized on the basis of qualitative and quantitative estimation of Pectinolytic, Xylanase and Cellulase activity. Out of 40 isolated strains only 3 were finally identified as efficient jute retting microorganism having high pectinolytic and Xylanase activity coupled with less Cellulase activity. These identified three micro organisms may provide a suitable means to develop a new retting technique especially under water stress condition
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