Social Media Based Deep Auto-Encoder Model for Clinical Recommendation

One of the most actively studied topics in modern medicine is the use of deep learning and patient clinical data to make medication and ADR recommendations. However, the clinical community still has some work to do in order to build a model that hybridises the recommendation system. As a social media learning based deep auto-encoder model for clinical recommendation, this research proposes a hybrid model that combines deep self-decoder with Top n similar co-patient information to produce a joint optimisation function (SAeCR). Implicit clinical information can be extracted using the network representation learning technique. Three experiments were conducted on two real-world social network data sets to assess the efficacy of the SAeCR model. As demonstrated by the experiments, the suggested model outperforms the other classification method on a larger and sparser data set. In addition, social network data can help doctors determine the nature of a patient's relationship with a co-patient. The SAeCR model is more effective since it incorporates insights from network representation learning and social theory

A CLINICAL STUDY TO EVALUATE ANTI-HYPERLIPIDEMIC EFFECT OF TGL COMPOUND IN DYSLIPIDEMIA VIS-A-VIS MEDODUSHTI

Dyslipidemia is a biochemical derangement found in number of disorders like Diabetes mellitus, Hypertension, Hypothyroidism etc. Dyslipidemia is an important risk factor for atherosclerosis, coronary artery disease and cerebrovascular disease. Epidemiological studies predict that for each 1% reduction in level of LDL-C there is 1% to 1.5% reduction in the risk of major cardiovascular events. Fewer than one half of patients in the United States discharged from the hospital with proven coronary disease receive treatment for Dyslipidemia given the proof that treating Dyslipidemia brings major benefits. Thusglobal views emphasize the need for early; effective interventions against the Atherogenic Dyslipidemia associated with Diabetic and Non-Diabetic cases and with metabolic syndrome to reduce the risk of premature cardiovascular diseases. In Ayurveda, it can be better correlated with Medodushti which is a functional condition and just a precursor stage of Medoroga and can be easily reversible by effective regimen. A single blind Study was carried out in OPD and IPD patients of Kayachikitsa department of Rishikul Campus, Haridwar for 90 days. Total 20 patients were registered for the trial and treated with TGL compound (Self-formulated drug). All the concerned approvals were obtained and data was analyzed under statistical parameters. A significantly reduction of cholesterol level, Triglycerides, VLDL, CHO/HDL Ratio and highly significant reduction of LDL and LDL/HDL Ratio was found. This research also proved the major role of Agni and Ama in pathogenesis of Dyslipidemia, and all the drugs having Dipana, Pachana, Ama nashaka, Kapha-Medohara, Rasayana and Srotoshodhaks quality will be highly effective.

Study of the hormonal and reproductive factors associated with low back pain in reproductive female

Background: Low back pain related disability and work absence accounts for high economical costs in modern society. A prevalence of 28-80% has been found with increase of prevalence with age and female preponderance.Methods: The present study was conducted on 250 non pregnant women complaining of low back pain attending department at Upper India Sugar Exchange Maternity Hospital, Department of Obstetrics and Gynaecology, GSVM Medical College, Kanpur during the period of one year. A brief questionnaire was used to screen, among the respondents, the occurrence of low back pain in the past year.Results: Low back pain was associated with high BMI, high waist circumference, more number of children, irregular and prolonged duration of menstruation, young maternal age at first birth and with history of abortion.Conclusions: Hormonal and reproductive factors are associated with low back pain.

The effects of isoflavones on bone density in postmenopausal women at tertiary centre

Background: The objective of study was to study the effect of isoflavone supplement on bone density of postmenopausal women.Methods: Women aged 49–65 y (n = 205) were enrolled in a double-blind, prospective randomized, placebo-controlled trial; 177 completed the trial. Bone density, body composition, bone turnover markers and diet were measured at baseline and after 12 months.Results: Loss of lumbar spine bone mineral content and bone mineral density was significantly lower in the women taking the isoflavone supplement than in those taking the placebo. Interactions between treatment group and menopausal status with respect to changes in other outcomes were not significant.Conclusions: These data suggest that, through attenuation of bone loss, isoflavones have a potentially protective effect on the lumbar spine and femur neck in women

Variation in physico-chemical properties of soil under different agri-horti system in Vindhyan region

Adoption of unsuitable production system may lead to deterioration of soil physico-chemical properties. Hence, it becomes important to assess the impact of various production systems. For this purpose, a study was carried out to find out variation in physico-chemical properties of soil in agri-horti system based four orchards of Rajiv Gandhi South Campus, Banaras Hindu University, Mirzapur, India. Soil samples were collected from the orchards of custard apple (Annona reticulate), guava (Psidium guajava), bael (Aegle marmelos) and crane berry (Carissa carandas) from two depths (0-15 and 15-30 cm) separately within canopy and out of canopy of different plants. The results of the study revealed that all the agri-horti systems were effective in bringing gradual improvement in the physico-chemical properties of the soil. Among different orchards tried, the custard apple system resulted in the highest improvement in temperature (27.16 oC), moisture (24.53 %) and water-holding capacity (41.80 %), whereas crane berry based system recorded better result in case of bulk density, porosity, electrical conductivity, pH, organic carbon, available N (187.55 kg ha-1) and K (193.46 kg ha-1). Custard apple based system recorded highest DTPA extractable micronutrients (Zn 0.54, Fe 17.23, Cu 0.88 and Mn14.72 mg ka-1)

Techno-Economic Aspects of Solid Food Wastes into Bio-Manure

Solid waste is health hazard and cause damage to the environment due to improper handling. Solid waste comprises of Industrial Waste (IW), Hazardous Waste (HW), Municipal Solid Waste (MSW), Electronic waste (E-waste), Bio-Medical Waste (BMW) which depend on their supply & characteristics. Food waste or Bio-waste composting and its role in sustainable development is explained in food waste is a growing area of concern with many costs to our community in terms of waste collection, disposal and greenhouse gases. When rotting food ends up in landfill it turns into methane, a greenhouse gas that is particularly damaging to the environment. Composting is biochemical process in which organic materials are biologically degraded, resulting in the production of organic by products and energy in the form of heat. Heat is trapped within the composting mass, leading to the phenomenon of self-heating.This overall process provide us Bio-Manure. Keywords: environment ,sustainable development ,food waste, Bio-Manur

SYNTHESIS OF COPPER NANOPARTICLES USING ASCORBIC ACID AND CETYL TRIMETHYL AMMONIUM BROMIDE

Objective: The present study highlights the development of a method to synthesize copper nanoparticles (CuNPs).Methods: CuNPs were developed using 0.01 M copper penta sulfate and 0.11 M of ascorbic acid (AA) and 0.03 M of cetyl trimethyl ammonium bromide solution. The synthesized CuNPs were differentiated through filtration and washed by water (deionized). CuNPs were kept in dialysis bag 70 KD in a 250 mL glass beaker along with distilled water. The assembly was kept on a magnetic stirrer for 24 h at 500 rpm. Then, the dialysis bag containing CuNPs solution was filtered by a filter assembly with 0.2 μm nylon filter. The filtered CuNPs were spray dried with the help of spray drier.Results: The prepared CuNPs were found to be 440 nm with zeta potential of −10 mV and polydispersity index 0.314.Conclusion: The investigation deciphers the promising and material technique to synthesis of CuNPs by methods for synthetic reduction utilizing strategy using AA (0.2 M) and sodium hydroxide (1 M), and Syloid 244FP

Influence of rice varieties and fertility levels on performance of rice and soil nutrient status under aerobic conditions

Scarcity of water resources in India is limiting the production of flooded rice crop. A field experiment was conducted in factorial RBD with sixteen treatment combinations including four rice varieties viz. V1: PR-115, V2: DRRH-3, V3: PAC-837 and V3: PR-121 and four fertility levels viz. F1: control (N0P0K0), F2: N, P2O5, K2O at 90: 45: 22.5 kg ha-1, F3: N, P2O5, K2O at 120:60:30 kg ha-1 and F4: N, P2O5, K2O at 150: 75: 37.5 kg ha-1 replicated thrice. The results revealed that among the different varieties, PAC-837 recorded highest plant height and number of tillers m-2 at all the growth stages. All yield attributes viz. number of effective tillers m-2, number of seeds per panicle, 1000-grain weight, spikelet sterility and grain yield, straw yield and harvest index significantly differed in different varieties and were recorded highest in PAC-837 which were however, statistically at par with DRRH-3 except grain yield and effective tillers m-2. Rice variety PAC-837 recorded highest grain yield of 45.65 q ha-1 and straw yield of 59.98 q ha-1. Among the fertility levels, number of effective tillers m-2 significantly increased up to 120: 60: 30 N-P2O5-K2O kg ha-1 thereafter nonsignificant differences were noticed. The grain and straw yield increased up to 150: 75: 37.5 N-P2O5-K2O kg ha-1 and recoded grain yield of 52.78 q ha-1 and straw yield of 73.85 q ha-1 with application of 150:75:37.5 N-P2O5-K2O kg ha-1. Nutrient application of 150: 75: 37.5 N-P2O5-K2O kg ha-1 recorded highest available N (238.16 kg ha-1), P (16.18 kg ha-1) and K (163.25 kg ha-1) in soil after harvest of the crop. Higher available nitrogen (235.28 kg ha-1), phosphorus (16.38 kg ha-1) and potassium (154.24 kg ha-1) n soil were recorded with PR-121 and lowest available major nutrients were recorded with variety PAC-837. This study would help to introduction and adaptation of new rice variety PAC-837 with application of 150: 75: 37.5 N-P2O5-K2O kg ha-1 under aerobic conditions in Shiwalik foothills region of North-Western Himalayas

Metamorphosing Indian Blockchain ecosystem

A blockchain is a decentralised database that is shared across computer network nodes. A blockchain acts as a database, storing information in a digital format. The study primarily aims to explore how in the future, block chain technology will alter several areas of the Indian economy. The current study aims to obtain a deeper understanding of blockchain technology's idea and implementation in India, as well as the technology's potential as a disruptive financial technological innovation. Secondary sources such as reports, journals, papers, and websites were used to compile all the data. Current and relevant information were utilised to help understand the research goals. All the information is rationally organised to fulfil the objectives. The current research focuses on recommendations for enhancing India's Blockchain ecosystem so that it may become one of the best in the world at utilising this new technology