An extension of Wiener integration with the use of operator theory

With the use of tensor product of Hilbert space, and a diagonalization procedure from operator theory, we derive an approximation formula for a general class of stochastic integrals. Further we establish a generalized Fourier expansion for these stochastic integrals. In our extension, we circumvent some of the limitations of the more widely used stochastic integral due to Wiener and Ito, i.e., stochastic integration with respect to Brownian motion. Finally we discuss the connection between the two approaches, as well as a priori estimates and applications.Comment: 13 page

DISTRIBUTION AND KINETICS OF 14C-VECURONIUM IN RATS AND MICE

The distribution and kinetics of 14C-vecuronium were studied in rats and mice. 14C-Vecuronium accumulated rapidly in the liver. Both unchanged and metabolized vecuronium were excreted with the bile into the intestines and stomach. Reabsorption in the gut was probably responsible for an enterohepatic increase in radioactivity in the liver after one hour. Excretion through the kidneys increased continuously from low values after the initial peak. Binding in compartments with acid mucopolysaccharides such as cartilage, connective tissue etc., was less important. Bloodbrain barrier and placenta were permeable only to a small degre

Exploring the multi-humped fission barrier of 238U via sub-barrier photofission

The photofission cross-section of 238U was measured at sub-barrier energies as a function of the gamma-ray energy using, for the first time, a monochromatic, high-brilliance, Compton-backscattered gamma-ray beam. The experiment was performed at the High Intensity gamma-ray Source (HIgS) facility at beam energies between E=4.7 MeV and 6.0 MeV and with ~3% energy resolution. Indications of transmission resonances have been observed at gamma-ray beam energies of E=5.1 MeV and 5.6 MeV with moderate amplitudes. The triple-humped fission barrier parameters of 238U have been determined by fitting EMPIRE-3.1 nuclear reaction code calculations to the experimental photofission cross section.Comment: 5 pages, 3 figure

Holographic Superconductor for a Lifshitz fixed point

We consider the gravity dual of strongly coupled system at a Lifshitz-fixed point and finite temperature, which was constructed in a recent work arXiv:0909.0263. We construct an Abelian Higgs model in that background and calculate condensation and conductivity using holographic techniques. We find that condensation happens and DC conductivity blows up when temperature turns below a critical value.Comment: 14 pages, 4 figures, v4: improved version, references adde

Mixed RG Flows and Hydrodynamics at Finite Holographic Screen

We consider quark-gluon plasma with chemical potential and study renormalization group flows of transport coefficients in the framework of gauge/gravity duality. We first study them using the flow equations and compare the results with hydrodynamic results by calculating the Green functions on the arbitrary slice. Two results match exactly. Transport coefficients at arbitrary scale is ontained by calculating hydrodynamics Green functions. When either momentum or charge vanishes, transport coefficients decouple from each other.Comment: 22 pages, 6 figure

Shear viscosity, instability and the upper bound of the Gauss-Bonnet coupling constant

We compute the dimensionality dependence of $\eta/s$ for charged black branes with Gauss-Bonnet correction. We find that both causality and stability constrain the value of Gauss-Bonnet coupling constant to be bounded by 1/4 in the infinite dimensionality limit. We further show that higher dimensionality stabilize the gravitational perturbation. The stabilization of the perturbation in higher dimensional space-time is a straightforward consequence of the Gauss-Bonnet coupling constant bound.Comment: 16 pages,3 figures+3 tables,typos corrected, published versio

Stochastic quantization and holographic Wilsonian renormalization group

We study relation between stochastic quantization and holographic Wilsonian renormalization group flow. Considering stochastic quantization of the boundary on-shell actions with the Dirichlet boundary condition for certain $AdS$ bulk gravity theories, we find that the radial flows of double trace deformations in the boundary effective actions are completely captured by stochastic time evolution with identification of the $AdS$ radial coordinate `$r$' with the stochastic time '$t$' as $r=t$. More precisely, we investigate Langevin dynamics and find an exact relation between radial flow of the double trace couplings and 2-point correlation functions in stochastic quantization. We also show that the radial evolution of double trace deformations in the boundary effective action and the stochastic time evolution of the Fokker-Planck action are the same. We demonstrate this relation with a couple of examples: (minimally coupled)massless scalar fields in $AdS_2$ and U(1) vector fields in $AdS_4$.Comment: 1+30 pages, a new subsection is added, references are adde

Latency Locus Complements MicroRNA 155 Deficiency In Vivo

MicroRNA-155 (miR-155) is expressed in many cancers. It also executes evolutionary conserved functions in normal B cell development. We show that the Kaposi's sarcoma-associated herpesvirus (KSHV) latency locus, which contains an ortholog of miR-155, miR-K12-11, complements B cell deficiencies in miR-155 knockout mice. Germinal center (GC) formation was rescued in spleen, lymph node, and Peyer's patches. Immunoglobulin levels were restored. This demonstrates that KSHV can complement the normal, physiological function of miR-155

Air Pollution and Lymphocyte Phenotype Proportions in Cord Blood

Effects of air pollution on morbidity and mortality may be mediated by alterations in immune competence. In this study we examined short-term associations of air pollution exposures with lymphocyte immunophenotypes in cord blood among 1,397 deliveries in two districts of the Czech Republic. We measured fine particulate matter < 2.5 μm in diameter (PM(2.5)) and 12 polycyclic aromatic hydrocarbons (PAHs) in 24-hr samples collected by versatile air pollution samplers. Cord blood samples were analyzed using a FACSort flow cytometer to determine phenotypes of CD3(+) T-lymphocytes and their subsets CD4(+) and CD8(+), CD19(+) B-lymphocytes, and natural killer cells. The mothers were interviewed regarding sociodemographic and lifestyle factors, and medical records were abstracted for obstetric, labor and delivery characteristics. During the period 1994 to 1998, the mean daily ambient concentration of PM(2.5) was 24.8 μg/m(3) and that of PAHs was 63.5 ng/m(3). In multiple linear regression models adjusted for temperature, season, and other covariates, average PAH or PM(2.5) levels during the 14 days before birth were associated with decreases in T-lymphocyte phenotype fractions (i.e., CD3(+) CD4(+), and CD8(+)), and a clear increase in the B-lymphocyte (CD19(+)) fraction. For a 100-ng/m(3) increase in PAHs, which represented approximately two standard deviations, the percentage decrease was −3.3% [95% confidence interval (CI), −5.6 to −1.0%] for CD3(+), −3.1% (95% CI, −4.9 to −1.3%) for CD4(+), and −1.0% (95% CI, −1.8 to −0.2%) for CD8(+) cells. The corresponding increase in the CD19(+) cell proportion was 1.7% (95% CI, 0.4 to 3.0%). Associations were similar but slightly weaker for PM(2.5). Ambient air pollution may influence the relative distribution of lymphocyte immunophenotypes of the fetus

The effects of social service contact on teenagers in England

Objective: This study investigated outcomes of social service contact during teenage years. Method: Secondary analysis was conducted of the Longitudinal Survey of Young People in England (N = 15,770), using data on reported contact with social services resulting from teenagers’ behavior. Outcomes considered were educational achievement and aspiration, mental health, and locus of control. Inverse-probability-weighted regression adjustment was used to estimate the effect of social service contact. Results: There was no significant difference between those who received social service contact and those who did not for mental health outcome or aspiration to apply to university. Those with contact had lower odds of achieving good exam results or of being confident in university acceptance if sought. Results for locus of control were mixed. Conclusions: Attention is needed to the role of social services in supporting the education of young people in difficulty. Further research is needed on the outcomes of social services contact