8,479 research outputs found
Multi axes vibration fixtures
A simplified technique and apparatus are described for testing the effects of vibration on various material specimen. Particular attention was given to tests along the orthogonal vibrational planes in order to prove the strength of the item under extraordinary conditions to which it will be subjected
Human Health Effects Assays
Discussion of the exponential increase in environmental toxicological information and an approach for organizing and using the information was presented by Lu and Wassom.1 A user\u27s guide to the Registry of Toxic Effects of Chemical Substances (RTECS) was published by NIOSH2 that defines the record layouts and describes the types of data contained in the computer tape version of the 1984 Edition of the RTECS.3 A text summarizing information on approximately 800 toxic chemicals was edited by Sittig.4 Milestone publications concerning fundamentals of toxicology with environmental applications included the works of Gentile,5 Ashby,6 Mortel mans,7 Thacker,8 and Ruppert.9 Brusick and Auletta10 discussed the developmental status of bioassays in genetic toxicology reviewed by the U. S. Environmental Protection Agency (EPA) Gene-Tox Work Groups
Bioremediation of Contaminated Surface Soils
Biological remediation of soils contaminated with organic chemicals is an alternative treatment technology that can often meet the goal of achieving a permanent clean-up remedy at hazardous waste sites, as encouraged by the U.S. Environmental Protection Agency (U.S. EPA) for implementation of The Superfund Amendments and Authorization Act (SARA) of 1986. Bioremediation is consistent with the philosophical thrust of SARA, for it involves the use of naturally occurring microorganisms to degrade and/or detoxify hazardous constituents in the soil at a contaminated slip to protect public health and the environment.Bioremediation of contaminated soils, including applications and limitations, has been addressed
Effect of Local Electron-Electron Correlation in Hydrogen-like Impurities in Ge
We have studied the electronic and local magnetic structure of the hydrogen
interstitial impurity at the tetrahedral site in diamond-structure Ge, using an
empirical tight binding + dynamical mean field theory approach because within
the local density approximation (LDA) Ge has no gap. We first establish that
within LDA the 1s spectral density bifurcates due to entanglement with the four
neighboring sp3 antibonding orbitals, providing an unanticipated richness of
behavior in determining under what conditions a local moment hyperdeep donor or
Anderson impurity will result, or on the other hand a gap state might appear.
Using a supercell approach, we show that the spectrum, the occupation, and the
local moment of the impurity state displays a strong dependence on the strength
of the local on-site Coulomb interaction U, the H-Ge hopping amplitude, the
depth of the bare 1s energy level epsilon_H, and we address to some extent the
impurity concentration dependence. In the isolated impurity, strong interaction
regime a local moment emerges over most of the parameter ranges indicating
magnetic activity, and spectral density structure very near (or in) the gap
suggests possible electrical activity in this regime.Comment: 9 pages, 5 figure
In Situ Bioremediation of Contaminated Unsaturated Subsurface Soils
An emerging technology for the remediation of unsaturated subsurface soils involves the use of microorganisms to degrade contaminants which are present in such soils. Understanding the processes which drive in situ bioremediation, as well as the effectiveness and efficiency of the utilization of these systems, are issues which have been identified by the Regional Superfund Engineering Forum as concerns of Superfund decision makers
Short-Chained Oligo(Ethylene Oxide)-Functionalized Gold Nanoparticles: Realization Of Significant Protein Resistance
Protein corona formed on nanomaterial surfaces play an important role in the bioavailability and cellular uptake of nanomaterials. Modification of surfaces with oligoethylene glycols (OEG) are a common way to improve the resistivity of nanomaterials to protein adsorption. Short-chain ethylene oxide (EO) oligomers have been shown to improve the protein resistance of planar Au surfaces. We describe the application of these EO oligomers for improved protein resistance of 30 nm spherical gold nanoparticles (AuNPs). Functionalized AuNPs were characterized using UV-Vis spectroscopy, dynamic light scattering (DLS), and zeta potential measurements. Capillary electrophoresis (CE) was used for separation and quantitation of AuNPs and AuNP-protein mixtures. Specifically, nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM) was employed for the determination of equilibrium and rate constants for binding between citrate-stabilized AuNPs and two model proteins, lysozyme and fibrinogen. Semi-quantitative CE analysis was carried out for mixtures of EO-functionalized AuNPs and proteins, and results demonstrated a 2.5-fold to 10-fold increase in protein binding resistance to lysozyme depending on the AuNP surface functionalization and a 15-fold increase in protein binding resistance to fibrinogen for both EO oligomers examined in this study
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Revised target co-ordinates for the Beagle 2 lander
The revised, IAU 2000 target co-ordinates of the Mars Beagle 2 lander are 11.6oN, 90.75oE
Redox-Active Nanomaterials For Nanomedicine Applications
Nanomedicine utilizes the remarkable properties of nanomaterials for the diagnosis, treatment, and prevention of disease. Many of these nanomaterials have been shown to have robust antioxidative properties, potentially functioning as strong scavengers of reactive oxygen species. Conversely, several nanomaterials have also been shown to promote the generation of reactive oxygen species, which may precipitate the onset of oxidative stress, a state that is thought to contribute to the development of a variety of adverse conditions. As such, the impacts of nanomaterials on biological entities are often associated with and influenced by their specific redox properties. In this review, we overview several classes of nanomaterials that have been or projected to be used across a wide range of biomedical applications, with discussion focusing on their unique redox properties. Nanomaterials examined include iron, cerium, and titanium metal oxide nanoparticles, gold, silver, and selenium nanoparticles, and various nanoscale carbon allotropes such as graphene, carbon nanotubes, fullerenes, and their derivatives/variations. Principal topics of discussion include the chemical mechanisms by which the nanomaterials directly interact with biological entities and the biological cascades that are thus indirectly impacted. Selected case studies highlighting the redox properties of nanomaterials and how they affect biological responses are used to exemplify the biologically-relevant redox mechanisms for each of the described nanomaterials
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The Beagle 2 environmental sensors: intended measurements and scientific goals
The Beagle 2 lander, due for arrival on Mars in December 2003, carries an Environmental Sensors Suite to monitor the local meteorology and carry out simple dust and oxidant measurements. The suite is described, and the scientific goals are discussed
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Beagle to the Moon: nn experiment package to measure polar ice and volatiles in permanently shadowed areas or beneath the lunar surface
The Beagle Science Package is a flight qualified set of instruments which should be deployed to the lunar surface to answer the questions about water and volatiles present in permanently shadowed regions and/or beneath the surface
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