1,025 research outputs found

    Three-dimensional diving behavior of ringed seals

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    Thesis (Ph.D.) University of Alaska Fairbanks, 2000The three-dimensional movements of 13 freely diving ringed seals were recorded during the spring of 1990, 1991, 1992, 1996, and 1997 in the Canadian Arctic near Resolute Bay, Nunavut. These data were used to investigate the diving behavior of ringed seals more fully than was possible using previous data, which only recorded the vertical movements of diving animals (time-depth data). During a third of all dives, ringed seals focused much of their effort within a reduced volume, suggesting local search behavior within patches of prey. Local search occurred during descent, ascent, and bottom phases (time spent at depth between the end of descent and the beginning of ascent) of dives, but local search most commonly occurred during bottom phases. Location data from five seals were detailed enough to allow analysis of three-dimensional movements within individual dives. Behaviors were defined for the dives of these five seals based on the character of movements within the dives. Ringed seal dives included horizontally convoluted, travel, and exploration dives, but vertically convoluted, rest, and sit-and-wait foraging dives were not observed. Horizontally convoluted (presumed foraging), travel, and exploration dive behaviors were defined with similar frequency for V-shaped dives (dives with only descent and ascent phases) and U-shaped dives (dives with descent, bottom, and ascent phases). The lack of behavioral differences between dives with distinct time-depth profiles suggested that time-depth profiles were not a reliable means of classifying behavioral dive types for ringed seals

    Mechatronic Camera Operator: Final Design Report

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    A mechatronic system is designed, constructed, and tested to aid filmmakers in the movement and control of a video camera. The system design allows for 6-DOF camera movement (movement in all three spatial directions, pan, tilt, and roll). The system is controlled by a human operator, using an implementation of a gamepad controller, and the system is battery-powered; the theoretical range of the system is therefore limited only by the onboard battery power, and the operator’s ability to keep within cord-length of the system as it moves. A misallocation of time resources resulted in an incomplete physical design, but preliminary testing indicates that the design is sound, and that mechanical specifications are sufficiently robust for a working final system. Further time and resources would be used to complete physical construction and electronic implementation, and to implement a feedback system to allow for closed-loop actuator control and the function of repeatable motio

    Queen discrimination by honeybee (Apis mellifera L) workers

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    A simple new technique for testing worker honeybees' ability to distinguish between honeybee queens is presented. Two queens were caged separately with groups of young sibling workers which were the daughters of another queen. The cages were exposed to the same environmental odours for 10 days. When placed in the test apparatus and given a choice of both queens, workers segregated towards the queen with which they had been caged. This provides further evidence that the distinctive odour of an individual queen is probably partly inherited and is learned by workers. The nature and functioning of queen odours are discussed

    Kennedy Space Center

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    This slide presentation reviews the importance of the Kennedy Space Center both in terms to the economy of Florida and to spaceflight. It reviews the general NASA direction,the challenges of the coming year and the accomplishments

    Reliable and accurate diagnostics from highly multiplexed sequencing assays

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    Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet these demands, and present promising alternatives to currently used RT-qPCR-based tests. However, reliable analysis, interpretation, and clinical use of HMSAs requires overcoming several computational, statistical and engineering challenges. Using recently acquired experimental data, we present and validate a computational workflow based on kallisto and bustools, that utilizes robust statistical methods and fast, memory efficient algorithms, to quickly, accurately and reliably process high-throughput sequencing data. We show that our workflow is effective at processing data from all recently proposed SARS-CoV-2 sequencing based diagnostic tests, and is generally applicable to any diagnostic HMSA

    Artificial diet sandwich reveals subsocial behavior in the coffee berry borer Hypothenemus hampei (Coleoptera: Curculionidae: Scolytinae)

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    An artificial diet sandwich, consisting of coffee berry borer artificial diet within two glass plates, has been developed to elucidate the behaviour of the coffee berry borer, an insect that in nature spends most of its life cycle inside the coffee berry. Various types of behaviour have been observed for the first time, including gallery construction, oviposition, gallery blocking, mating and most remarkably, subsocial tasks such as maternal sanitation and tending of eggs and larvae. This observational technique is a breakthrough for studies and manipulations of the coffee berry borer's social behaviour and could be applicable to other bark beetles, consequently yielding important insights into the origin of parental care in scolytine beetles

    Reproduced from the journal Health Physics with permission from the Health Physics Society

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    ABSTRACT The models used in the NRC approach to assess chronic atmospheric releases of radioactivity generate deterministic dose estimates by using standard assumptions about exposure conditions and environmental transport mechanisms. This approach has been used at the Savannah River Site since 1983. Total dose to off-site maximum individuals at the SRS from atmospheric releases has been on the order of 1 µSv/yr, three orders of magnitude lower than the applicable dose limit. When estimating atmospheric dose many parameters remain unchanged each time calculations are performed. These parameters, therefore, are essentially unimportant with regard to routine modeling. It is proposed, therefore, that transport and dosimetry models can be reduced to simple functions of a few parameters that essentially determine dose at all locations across the site. The three-parameter transport and dosimetry model developed in this work is useful for quick and easy estimates of chronic atmospheric tritium dose that are within a factor of 2 of estimates by more sophisticated models. The three parameters critical to estimating annual average concentration at the Savannah River Site are wind-direction frequency, downwind distance, and physical stack height. The model is bounded by physical stack heights between 10 and 61 meters and downwind distances between 800 m (0.5 mi.) and 32 km (20 mi.) and should not be used outside its intended domain. It requires knowledge of wind-direction frequency, downwind distance, and physical stack height to estimate an Atmospheric Dose Factor (ADF; in units of µSv/GBq) for the conversion of long-term release activity to maximum individual effective dose equivalent. This concept is being carried forward to the development of a reduced model for particulate emissions from SRS stacks.

    Interventions for preventing delirium in hospitalised non-ICU patients

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    BACKGROUND: Delirium is a common mental disorder, which is distressing and has serious adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the perspective of patients and carers, and healthcare providers. It is currently unclear, however, whether interventions for preventing delirium are effective. OBJECTIVES: To assess the effectiveness of interventions for preventing delirium in hospitalised non-Intensive Care Unit (ICU) patients. SEARCH METHODS: We searched ALOIS - the Cochrane Dementia and Cognitive Improvement Group's Specialized Register on 4 December 2015 for all randomised studies on preventing delirium. We also searched MEDLINE (Ovid SP), EMBASE (Ovid SP), PsycINFO (Ovid SP), Central (The Cochrane Library), CINAHL (EBSCOhost), LILACS (BIREME), Web of Science core collection (ISI Web of Science), ClinicalTrials.gov and the WHO meta register of trials, ICTRP. SELECTION CRITERIA: We included randomised controlled trials (RCTs) of single and multi- component non-pharmacological and pharmacological interventions for preventing delirium in hospitalised non-ICU patients. DATA COLLECTION AND ANALYSIS: Two review authors examined titles and abstracts of citations identified by the search for eligibility and extracted data independently, with any disagreements settled by consensus. The primary outcome was incidence of delirium; secondary outcomes included duration and severity of delirium, institutional care at discharge, quality of life and healthcare costs. We used risk ratios (RRs) as measures of treatment effect for dichotomous outcomes; and between group mean differences and standard deviations for continuous outcomes. MAIN RESULTS: We included 39 trials that recruited 16,082 participants, assessing 22 different interventions or comparisons. Fourteen trials were placebo-controlled, 15 evaluated a delirium prevention intervention against usual care, and 10 compared two different interventions. Thirty-two studies were conducted in patients undergoing surgery, the majority in orthopaedic settings. Seven studies were conducted in general medical or geriatric medicine settings.We found multi-component interventions reduced the incidence of delirium compared to usual care (RR 0.69, 95% CI 0.59 to 0.81; seven studies; 1950 participants; moderate-quality evidence). Effect sizes were similar in medical (RR 0.63, 95% CI 0.43 to 0.92; four studies; 1365 participants) and surgical settings (RR 0.71, 95% CI 0.59 to 0.85; three studies; 585 participants). In the subgroup of patients with pre-existing dementia, the effect of multi-component interventions remains uncertain (RR 0.90, 95% CI 0.59 to 1.36; one study, 50 participants; low-quality evidence).There is no clear evidence that cholinesterase inhibitors are effective in preventing delirium compared to placebo (RR 0.68, 95% CI, 0.17 to 2.62; two studies, 113 participants; very low-quality evidence).Three trials provide no clear evidence of an effect of antipsychotic medications as a group on the incidence of delirium (RR 0.73, 95% CI, 0.33 to 1.59; 916 participants; very low-quality evidence). In a pre-planned subgroup analysis there was no evidence for effectiveness of a typical antipsychotic (haloperidol) (RR 1.05, 95% CI 0.69 to 1.60; two studies; 516 participants, low-quality evidence). However, delirium incidence was lower (RR 0.36, 95% CI 0.24 to 0.52; one study; 400 participants, moderate-quality evidence) for patients treated with an atypical antipsychotic (olanzapine) compared to placebo (moderate-quality evidence).There is no clear evidence that melatonin or melatonin agonists reduce delirium incidence compared to placebo (RR 0.41, 95% CI 0.09 to 1.89; three studies, 529 participants; low-quality evidence).There is moderate-quality evidence that Bispectral Index (BIS)-guided anaesthesia reduces the incidence of delirium compared to BIS-blinded anaesthesia or clinical judgement (RR 0.71, 95% CI 0.60 to 0.85; two studies; 2057 participants).It is not possible to generate robust evidence statements for a range of additional pharmacological and anaesthetic interventions due to small numbers of trials, of variable methodological quality. AUTHORS' CONCLUSIONS: There is strong evidence supporting multi-component interventions to prevent delirium in hospitalised patients. There is no clear evidence that cholinesterase inhibitors, antipsychotic medication or melatonin reduce the incidence of delirium. Using the Bispectral Index to monitor and control depth of anaesthesia reduces the incidence of postoperative delirium. The role of drugs and other anaesthetic techniques to prevent delirium remains uncertain
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