751 research outputs found

    Effects of participatory learning programs in middle and high school civic education

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    Introduction of participatory learning program in school civic education increases student awareness and improves communication skills through active participation in community services. Citizen Education Clearing House (CECH) programs which include the election, the Missouri state government, and the metropolitan issues program, enable students to improve their basic knowledge of election procedures and awareness of youth violence. A study of students from different racial and academic backgrounds who participated in these programs, reveals that participation leads to better civic education

    A Controlled Study on the Characterisation of Bioaerosols Emissions from Compost

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    Bioaerosol emissions arising from biowaste treatment are an issue of public concern. To better characterise the bioaerosols, and to assess a range of measurement methods, we aerosolised green waste compost under controlled conditions. Viable and non-viable Andersen samplers, cyclone samplers and a real time bioaerosol detection system (Spectral Intensity Bioaerosol Sensor (SIBS)) were deployed simultaneously. The number-weighted fraction of fluorescent particles was in the range 22–26% of all particles for low and high emission scenarios. Overall fluorescence spectral profiles seen by the SIBS exhibited several peaks across the 16 wavelength bands from 298 to 735 nm. The size-fractionated endotoxin profile showed most endotoxin resided in the 2.1–9 μm aerodynamic diameter fraction, though up to 27% was found in a finer size fraction. A range of microorganisms were detected through culture, Matrix Assisted Laser Desorption and Ionisation Time of Flight Mass Spectrometry (MALDI-TOF) and quantitative polymerase chain reaction (qPCR), including Legionella pneumophila serogroup 1. These findings contribute to our knowledge of the physico-chemical and biological characteristics of bioaerosols from composting sites, as well as informing future monitoring approaches and data interpretation for bioaerosol measurement

    New Media Masculinities: How YouTube Influencers Incubate Masculine Ideologies and Mentor Males Through Gender Role Conflict/Stress

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    This chapter uses a Gender Role Conflict Theory (GRC) lens to analyze the ways in which three YouTube opinion-and-lifestyle influencers—with large adolescent male audiences—negotiate and amplify their ideals of masculinity and male identity development in the 21st century. Each influencer advocates a competing solution to contemporary male GRC which they frame as a crisis of masculinity. Using rhetorical analysis techniques, we unpack, compare, and contrast three clips from each influencer to closely examine the ways they define masculinity and its complexities, as well as their solutions to stressors experienced by young men. Three distinct frames emerge in each influencer’s configuration of a crisis of masculinity, each linked to different male GRC stressors. These results are situated amidst a broader landscape of gender and socio-political commentary on social media platforms. We connect the three influencers’ messages to current discourses of hegemonic, hybrid, and counterhegemonic masculinities circulating across YouTube

    A lower bound for the BCS functional with boundary conditions at infinity

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    We consider a many-body system of fermionic atoms interacting via a local pair potential and subject to an external potential within the framework of BCS theory. We measure the free energy of the whole sample with respect to the free energy of a reference state which allows us to define a BCS functional with boundary conditions at infinity. Our main result is a lower bound for this energy functional in terms of expressions that typically appear in Ginzburg-Landau functionals.Comment: 32 page

    Invasive Lobular Breast Cancer as a Distinct Disease: Implications for Therapeutic Strategy

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    Invasive lobular carcinoma comprises 10–15% of all breast cancers and is increasingly recognised as a distinct and understudied disease compared with the predominant histological subtype, invasive ductal carcinoma. Hallmarks of invasive lobular carcinoma include E-cadherin loss, leading to discohesive morphology with cells proliferating in single-file strands and oestrogen receptor positivity, with favourable response to endocrine therapy. This review summarises the distinct histological and molecular features of invasive lobular carcinoma with focus on diagnostic challenges and the impact on surgical management and medical therapy. Emphasis is placed on recent advances in our understanding of the unique molecular biology of lobular breast cancer and how this is optimising our therapy approach in the clinic

    Lateral Gene Transfer Drives Metabolic Flexibility in the Anaerobic Methane-Oxidizing Archaeal Family Methanoperedenaceae

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    Anaerobic oxidation of methane (AOM) is an important biological process responsible for controlling the flux of methane into the atmosphere. Members of the archaeal family Methanoperedenaceae (formerly ANME-2d) have been demonstrated to couple AOM to the reduction of nitrate, iron, and manganese. Here, comparative genomic analysis of 16 Methanoperedenaceace metagenome-assembled genomes (MAGs), recovered from diverse environments, revealed novel respiratory strategies acquired through lateral gene transfer (LGT) events from diverse archaea and bacteria. Comprehensive phylogenetic analyses suggests that LGT has allowed members of the Methanoperedenaceae to acquire genes for the oxidation of hydrogen and formate, and the reduction of arsenate, selenate and elemental sulfur. Numerous membrane-bound multi-heme c type cytochrome complexes also appear to have been laterally acquired, which may be involved in the direct transfer of electrons to metal oxides, humics and syntrophic partners

    1-[6-(6-Acetyl­pyridin-2-yl)pyridin-2-yl]ethanone

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    In the title compound, C14H12N2O2, the asymmetric unit comprises one half-mol­ecule with an inversion center between the pyridine rings. The rings are trans coplanar with the acetyl groups deviating slightly from the mean planes, making a dihedral angle of 4.63 (4)°. In the crystal, mol­ecules are linked by weak inter­molecular C—H⋯O hydrogen bonds, forming a supra­molecular sheet parallel to (100)

    Scoping studies to establish the capability and utility of a real-time bioaerosol sensor to characterise emissions from environmental sources

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    A novel dual excitation wavelength based bioaerosol sensor with multiple fluorescence bands called Spectral Intensity Bioaerosol Sensor (SIBS) has been assessed across five contrasting outdoor environments. The mean concentrations of total and fluorescent particles across the sites were highly variable being the highest at the agricultural farm (2.6 cm−3 and 0.48 cm−3, respectively) and the composting site (2.32 cm−3 and 0.46 cm−3, respectively) and the lowest at the dairy farm (1.03 cm−3 and 0.24 cm−3, respectively) and the sewage treatment works (1.03 cm−3 and 0.25 cm−3, respectively). In contrast, the number-weighted fluorescent fraction was lowest at the agricultural site (0.18) in comparison to the other sites indicating high variability in nature and magnitude of emissions from environmental sources. The fluorescence emissions data demonstrated that the spectra at different sites were multimodal with intensity differences largely at wavelengths located in secondary emission peaks for λex 280 and λex 370. This finding suggests differences in the molecular composition of emissions at these sites which can help to identify distinct fluorescence signature of different environmental sources. Overall this study demonstrated that SIBS provides additional spectral information compared to existing instruments and capability to resolve spectrally integrated signals from relevant biological fluorophores could improve selectivity and thus enhance discrimination and classification strategies for real-time characterisation of bioaerosols from environmental sources. However, detailed lab-based measurements in conjunction with real-world studies and improved numerical methods are required to optimise and validate these highly resolved spectral signatures with respect to the diverse atmospherically relevant biological fluorophores
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