7,589 research outputs found

    Hyperfine Level Splitting for Hydrogen-Like Ions due to Rotation-Spin Coupling

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    The theoretical aspects of spin-rotation coupling are presented. The approach is based on the general covariance principle. It is shown that the gyrogravitational ratio of the bare spin-1/2 and the spin-1 particles is equal unity. That is why spin couples with rotation as an ordinary angular momentum. This result is the rigorous substantiation of the cranking model. To observe the phenomenon, the experiment with hydrogen-like ions in a storage ring is suggested. It is found that the splitting of the 12!S1/2,F=1/21 ^2!S_{1/2}, F=1/2 hyperfine state of the 140Pr58+^{140}{\rm Pr}^{58+} and 142Pm60+^{142}{\rm Pm}^{60+} ions circulating in the storage ring ESR in Darmstadt along a helical trajectory is about 4.5 MHz. We argue that such splitting can be experimentally determined by means of the ionic interferometry.Comment: 6 pages, final versio

    Image Coaddition with Temporally Varying Kernels

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    Large, multi-frequency imaging surveys, such as the Large Synaptic Survey Telescope (LSST), need to do near-real time analysis of very large datasets. This raises a host of statistical and computational problems where standard methods do not work. In this paper, we study a proposed method for combining stacks of images into a single summary image, sometimes referred to as a template. This task is commonly referred to as image coaddition. In part, we focus on a method proposed in previous work, which outlines a procedure for combining stacks of images in an online fashion in the Fourier domain. We evaluate this method by comparing it to two straightforward methods through the use of various criteria and simulations. Note that the goal is not to propose these comparison methods for use in their own right, but to ensure that additional complexity also provides substantially improved performance

    Inhaled insulin for controlling blood glucose in patients with diabetes

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    Diabetes mellitus is a significant worldwide health problem, with the incidence of type 2 diabetes increasing at alarming rates. Insulin resistance and dysregulated blood glucose control are established risk factors for microvascular complications and cardiovascular disease. Despite the recognition of diabetes as a major health issue and the availability of a growing number of medications designed to counteract its detrimental effects, real and perceived barriers remain that prevent patients from achieving optimal blood glucose control. The development and utilization of inhaled insulin as a novel insulin delivery system may positively influence patient treatment adherence and optimal glycemic control, potentially leading to a reduction in cardiovascular complications in patients with diabetes

    Properties of the series solution for Painlevé I

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    We present some observations on the asymptotic behaviour of the coefficients in the Laurent series expansion of solutions of the first Painlevé equation. For the general solution, explicit recursive formulae for the Taylor expansion of the tau-function around a zero are given, which are natural extensions of analogous formulae for the elliptic sigma function, as given by Weierstrass. Numerical and exact results on the symmetric solution which is singular at the origin are also presented

    Bimodal release ondansetron for acute gastroenteritis among adolescents and adults: A randomized clinical trial

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    Importance: Vomiting resulting from acute gastroenteritis is commonly treated with intravenous antiemetics in acute care settings. If oral treatment were beneficial, patients might not need intravenous administered hydration or medication. Furthermore, a long-acting treatment could provide sustained relief from nausea and vomiting. Objective: To determine whether an experimental long-acting bimodal release ondansetron tablet decreases gastroenteritis-related vomiting and eliminates the need for intravenous therapy for 24 hours after administration. Design, Setting, and Participants: This placebo-controlled, double-blind, randomized clinical trial included patients from 19 emergency departments and 2 urgent care centers in the United States from December 8, 2014, to February 17, 2017. Patients 12 years and older with at least 2 vomiting episodes from presumed gastroenteritis in the previous 4 hours and symptoms with less than 36 hours\u27 duration were randomized using a 3:2 active to placebo ratio. Analyses were performed on an intent-to-treat basis and conducted from June 1, 2017, to November 1, 2017. Intervention: Bimodal release ondansetron tablet containing 6 mg of immediate release ondansetron and 18 mg of a 24-hour release matrix for a total of 24 mg of ondansetron. Main Outcomes and Measures: Treatment success was defined as no further vomiting, no need for rescue medication, and no intravenous hydration for 24 hours after bimodal release ondansetron administration. Results: Analysis included 321 patients (mean [SD] age, 29.0 [11.1] years; 195 [60.7%] women), with 192 patients in the bimodal release ondansetron group and 129 patients in the placebo group. Treatment successes were observed in 126 patients in the bimodal release ondansetron group (65.6%) compared with 70 patients in the placebo group (54.3%), with an 11.4% (95% CI, 0.3%-22.4%) absolute probability difference. The proportion of treatment success was 21% higher among patients who received bimodal release ondansetron compared with those who received a placebo (relative risk, 1.21; 95% CI, 1.00-1.46; P = .04). In an analysis including only patients with a discharge diagnosis of acute gastroenteritis and no major protocol violations, there were 123 treatment successes (69.5%) in the bimodal release ondansetron group compared with 67 treatment successes (54.9%) in the placebo group (relative risk, 1.27; 95% CI, 1.05-1.53; P = .01). Adverse effects were infrequent and similar to the known safety profile of ondansetron. Conclusions and Relevance: This randomized clinical trial found that a long-acting bimodal release oral ondansetron tablet was an effective antiemetic among adolescents and adults with moderate to severe vomiting from acute gastroenteritis. The drug benefits extended to 24 hours after administration. Bimodal release ondansetron may decrease the need for intravenous access and emergency department care to manage acute gastroenteritis. Trial Registration: ClinicalTrials.gov identifier: NCT02246439

    Correlation Effects in Nuclear Transparency

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    The Glauber approximation is used to calculate the contribution of nucleon correlations in high-energy A(e,eN)A(e,e'N) reactions. When the excitation energy of the residual nucleus is small, the increase of the nuclear transparency due to correlations between the struck nucleon and the other nucleons is mostly compensated by a decrease of the transparency due to the correlations between non detected nucleons. We derive Glauber model predictions for nuclear transparency for the differential cross section when nuclear shell level excitations are measured. The role of correlations in color transparency is briefly discussed.Comment: 24 pages revtex, 4 uuencoded PostScript Figures as separate fil
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