Investigation of aspects of the interaction of the indicators of lipid exchange, trombocitarian block of hemostasis, total body reactivity and their influence on the psychosomatic harmonization of the man in chronic inflammatory processes

For the first time on the basis of clinical and laboratory researches were revealed the correlation of indicators of lipid metabolism, platelet level of hemostasis and general reactivity in patients with chronic inflammatory processes of the genital system. The new pathogenetic aspects of the course of inflammatory diseases have been established. It has been shown that chronic inflammatory process is accompanied by disorders of lipid metabolism. The degree of severity of these changes depends on the severity of the inflammatory process, the reduction of phagocytic activity of polymorphonuclear leukocytes and the activation of macrophage and specific cellular mechanisms, accompanied by auto-intoxication. It is established that the frequency of atherogenic dyslipoproteinemias, as well as the intensity of lipid peroxidation increases in accordance with the increase age of the examined patients. Most atherogenic dyslipoproteinemias are found in patients with viral and chlamydial infections. The summarized data of the correlation analysis allow us to establish that the growth of atherogenic properties of blood plasma of patients with chronic inflammatory processes of the reproductive system occurs in accordance with the increase of adhesive-aggregation properties of platelets and damage of the vascular endothelium. These shifts occur in parallel with the predominance of the monocyte-macrophage linkage of phagocytosis against the background of reduced activity of neutrophils and cellular mechanisms of development of immunopathological reactions

Natural Therapy as Integral Technology of Social and Physical Rehabilitation

The concept of natural therapy is a product of the evolution of social work theories. The ecological model of social work was formed in the 60s of the twentieth century and assumed the inclusion of an ecological context in the social sphere and social work as a practical activity. In the 21st century, environmental methods of social work have changed the focus and social rehabilitation has become a priority using such environmental technologies as animal therapy, garden therapy, agrotherapy, aesthetic therapy, and so on. The article examines the Ukrainian national experience in the development of social and physical rehabilitation of various categories of the population using environmental technologies. One of the main features of the formation of national experience of the concept of natural therapy is that today the use of its components is at the initial level. The technologies for animal-assisted therapy are somewhat better developed in comparison with agrotherapy and garden therapy. The combination of these technologies into a single rehabilitation complex makes it possible to use the advantages of each of these technologies (animal therapy, agrotherapy and garden therapy) to achieve the maximum rehabilitation effect for each client, which requires social and physical rehabilitation

Natural Therapy as Integral Technology of Social and Physical Rehabilitation

The concept of natural therapy is a product of the evolution of social work theories. The ecological model of social work was formed in the 60s of the twentieth century and assumed the inclusion of an ecological context in the social sphere and social work as a practical activity. In the 21st century, environmental methods of social work have changed the focus and social rehabilitation has become a priority using such environmental technologies as animal therapy, garden therapy, agrotherapy, aesthetic therapy, and so on. The article examines the Ukrainian national experience in the development of social and physical rehabilitation of various categories of the population using environmental technologies. One of the main features of the formation of national experience of the concept of natural therapy is that today the use of its components is at the initial level. The technologies for animal-assisted therapy are somewhat better developed in comparison with agrotherapy and garden therapy. The combination of these technologies into a single rehabilitation complex makes it possible to use the advantages of each of these technologies (animal therapy, agrotherapy and garden therapy) to achieve the maximum rehabilitation effect for each client, which requires social and physical rehabilitation

Features of Indicators of Blood General Clinical Analysis and the Summary Analysis of an Organism’s General Reactivity at Chronic Inflammatory Process

Inflammatory diseases cause health disorders which result in a reduction of the population. That is why this medical problem is considered to be a very important one. The human immune system is responsible for protecting the body from infections of various origins, while inducing chronic inflammation (characterized by a long, often invisible course) which can result in proneness to recurrence, complications and resistance to therapy. The authors of the article analyzed and proved that there are immune status shifts in patients with chronic nonspecific inflammatory processes depending on the pathogen, phase and level of damage

Assessment of the State of Platelet Haemostasis and Adhesive - Aggregation Properties of Platelets as a Factor of Increasing the Tendency to Thrombosis in Chronic Inflammation

In recent decades, considerable progress has been made in understanding the functional mechanisms of platelets and the correction of platelet haemostasis. Platelets are considered the most important participants in both the normal and pathological thrombotic processes characteristic of a variety of diseases and conditions. Alterations in various limbs of haemostasis are found in many somatic diseases (atherosclerosis, coronary heart disease, stroke), surgical procedures, oncological and immunological diseases. Inflammation underlies most diseases and remains an urgent problem in medicine. In the leukocyte infiltration of the inflammatory focus, the mechanism of its self-preservation is of great importance. The activation of haematopoiesis during inflammation is triggered by factors released by stimulated leukocytes of the focus and peripheral blood. Therefore, the problem of the state of the haemostasis system should be the focus of constant attention of clinicians, and with the help of laboratory monitoring of the state of the haemostasis system, it is possible to carry out drug correction of the haemocoagulation potential

Assessment of the Nature of Dyslipoproteinemias and Correlations of Indicators of General Reactivity and Lipid Metabolism in Patients with Chronic Nonspecific Inflammation of the Reproductive System

Metabolic disorders can occur at all levels of biological organization - from molecular and cellular to the level of the organism as a whole. These changes may result from disruptions in hormonal mechanisms, actions of pathogenic factors, or infections. Primary metabolic disorders are the basis of many diseases, such as diabetes, obesity, and atherosclerosis, while secondary disorders accompany most pathological processes. Disruption of lipid metabolism leads to changes in their functions and the development of pathological processes, such as dyslipoproteinemia, and also contributes to the development of atherosclerosis. Various intracellular infectious agents play a significant role in the development of dyslipoproteinemias and atherosclerosis, for example, chlamydia can alter the lipid metabolism in macrophages under the influence of low-density lipoproteins, leading to the formation of 'foam-like' cells. This, in turn, contributes to the development of atheromatous plaques-a favorable environment for chlamydia, where it can survive for an extended period and trigger immunopathological mechanisms

Peculiarities of the State of the Body's Immunoprotective Functions, Bacterioscopic and Cytological Studies in the Presence of a Chronic Inflammatory Process of the Reproductive System

At the current stage, the state of health of the Ukrainian nation of reproductive age is characterized by a low birth rate. Chronic inflammatory diseases of the reproductive system significantly affect the health of millions of people of childbearing age. Chronic inflammation is characterized by a protracted, often erased course, a tendency to relapse, the presence of complications and resistance to therapy. The development and formation of inflammatory diseases are based on interconnected processes that begin with acute inflammation and end with destructive changes, therefore the assessment of the body's adaptive capabilities is increasingly considered one of the most important health criteria. There is a whole series of integral hematological indicators that allow you to assess the state of various parts of the immune system without resorting to special research methods

Psychological and Pedagogical Aspects of Consolidation of Social Capital of Higher Education Institutions

The aim of the study was to identify psychological and pedagogical factors that ensure the consolidation of social capital in higher education institutions and to assess their effectiveness through expert critical evaluations. The study used the exploratory design and was based on the use of qualitative methods to evaluate the selected studies. The research methodology relied on the methods recommended for feasibility studies to determine the possibility of implementation of the selected best practices. The systematic review of scientific sources and best practices found the psychological and pedagogical aspects that ensure the consolidation of social capital in higher education institutions, namely: individual psychological factors of economically motivated behaviour, social network technology, second-order psychological factors, teachers' assistance of students' professional self-determination, education as a means, and psychological factors based on the attributes of the institution. The results of expert evaluation of the above factors suggest that the last three ones mentioned have the potential for duplication, dissemination and transferability in higher education institutions in Ukraine