Simulation Studies of Delta-ray Backgrounds in a Compton-Scatter Transition Radiation Detector

In order to evaluate the response to cosmic-ray nuclei of a Compton-Scatter Transition Radiation Detector in the proposed ACCESS space-based mission, a hybrid Monte Carlo simulation using GEANT3 and an external transition radiation (TR) generator routine was constructed. This simulation was employed to study the effects of delta-ray production induced by high-energy nuclei and to maximize the ratio of TR to delta-ray background. The results demonstrate the ability of a Compton-Scatter Transition Radiation Detector to measure nuclei from boron to iron up to Lorentz factors ~ 10^5 taking into account the steeply falling power-law cosmic ray spectra.Comment: Presented at TRDs for the 3rd millennium: Third Workshop on advanced Transition Radiation Detectors for accelerator and space applications, Ostuni, Italy, September 2005, 4 pages, 2 figure

Biological protection in deep space missions

During deep space missions, astronauts are exposed to highly ionizing radiation, incl. neutrons, protons and heavy ions from galactic cosmic rays (GCR), solar wind (SW) and solar energetic particles (SEP). This increase the risks for cancerogenisis, damages in central nervous system (CNS), cardiovascular diseases, etc. Large SEP events can even cause acute radiation syndrome (ARS). Long term manned deep space missions will therefor require unique radiation protection strategies. Since it has been shown that physical shielding alone is not sufficient, this paper propose pre-flight screening of the aspirants for evaluation of their level of adaptive responses. Methods for boosting their immune system, should also be further investigated, and the possibility of using radiation effect modulators are discussed. In this paper, especially, the use of vitamin C as a promising non-toxic, cost-effective, easily available radiation mitigator (which can be used hours after irradiation), is described. Although it has previously been shown that vitamin C can decrease radiation-induced chromosomal damage in rodents, it must be further investigated before any conclusions about its radiation mitigating properties in humans can be concluded

Improved parametrization of the transparency parameter in Kox and Shen models of total reaction cross sections

The total reaction cross section is an essential quantity in particle and heavy-ion transport codes when determining the mean free path of a transported particle. Many transport codes determine the distance a particle is transported before it collides with the target or is stopped in the target material, with the Monte Carlo (MC) method using semiempirical parametrization models for the total reaction cross sections. In order to improve the well-known Kox and Shen models of total reaction cross sections and allow the models to be used at energies below 30 MeV/nucleon, we propose a modified parametrization of the transparency parameter. We also report that the Kox and Shen models have a projectile-target asymmetry and should be used so that the lighter nucleus is always treated as the projectile

Simulations of MATROSHKA experiments at ISS using PHITS

Concerns about the biological effects of space radiation are increasing rapidly due to the perspective of long-duration manned missions, both in relation to the International Space Station (ISS) and to manned interplanetary missions to Moon and Mars in the future. As a preparation for these long duration space missions it is important to ensure an excellent capability to evaluate the impact of space radiation on human health in order to secure the safety of the astronauts/cosmonauts and minimize their risks. It is therefore necessary to measure the radiation load on the personnel both inside and outside the space vehicles and certify that organ and tissue equivalent doses can be simulated as accurate as possible. In this paper we will present simulations using the three-dimensional Monte Carlo Particle and Heavy Ion Transport code System (PHITS) of long term dose measurements performed with the ESA supported experiment MATROSHKA (MTR), which is an anthropomorphic phantom containing over 6000 radiation detectors, mimicking a human head and torso. The MTR experiment, led by the German Aerospace Center (DLR), was launched in January 2004 and has measured the absorbed dose from space radiation both inside and outside the ISS. In this paper preliminary comparisons of measurements outside the ISS will be presented. The results confirm previous calculations and measurements which indicate that PHITS is a suitable tool for estimations of dose received from cosmic radiation and when performing shielding design studies of spacecraft

Emade teadmised ja arusaamad imetamisest ning nende hinnangud imetamisnõustamisele Eestis: veebipõhine küsitlusuurimus

https://www.ester.ee/record=b518607

CEM2k and LAQGSM as Event Generators for Space-Radiation-Shielding and Cosmic-Ray-Propagation Applications

The CEM2k and LAQGSM codes have been recently developed at Los Alamos National Laboratory to simulate nuclear reactions for a number of applications. We have benchmarked our codes against most available measured data at incident particle energies from 10 MeV to 800 GeV and have compared our results with predictions of other current models used by the nuclear community. Here, we present a brief description of our codes and show illustrative results to show that CEM2k and LAQGSM can be used as reliable event generators for space-radiation-shielding, cosmic-ray-propagation, and other astrophysical applications. Finally, we show the use of our calculated cross sections together with experimental data from our LANL T-16 compilation to produce evaluated files which we use in the GALPROP model of galactic particle propagation to better constrain the size of the CR halo.Comment: 10 pages, 9 figures, LaTeX, talk given at the World Space Congress 2002, 34th COSPAR Scientific Assembly, Houston, Texas, USA, 10-19 October 2002, to appear in Advances in Space Researc

Requirements for designing an effective metallic nanoparticle (NP)-boosted radiation therapy (RT)

Many different tumor-targeted strategies are under development worldwide to limit the side effects and improve the effectiveness of cancer therapies. One promising method is to enhance the radiosensitization of the cancer cells while reducing or maintaining the normal tissue complica-tion probability during radiation therapy using metallic nanoparticles (NPs). Radiotherapy with MV photons is more commonly available and applied in cancer clinics than high LET particle radi-otherapy, so the addition of high-Z NPs has the potential to further increase the efficacy of photon radiotherapy in terms of NP radiosensitization. Generally, when using X-rays, mainly the inner electron shells are ionized, which creates cascades of both low and high energy Auger electrons. When using high LET particles, mainly the outer shells are ionized, which give electrons with lower energies than when using X-rays. The amount of the produced low energy electrons is higher when exposing NPs to heavy charged particles than when exposing them to X-rays. Since ions traverse the material along tracks, and therefore give rise to a much more inhomogeneous dose distributions than X-rays, there might be a need to introduce a higher number of NPs when using ions compared to when using X-rays to create enough primary and secondary electrons to get the desired dose escalations. This raises the questions of toxicity. This paper provides a review of the fundamental processes controlling the outcome of metallic NP-boosted photon beam and ion beam radiation therapy and presents some experimental procedures to study the biological effects of NPs’ radio-sensitization. The overview shows the need for more systematic studies of the behavior of NPs when exposed to different kinds of ionizing radiation before applying metallic-based NPs in clinical practice to improve the effect of IR therapy

Evaluating the Strength of a Hypothesis on How Terrestrial Organisms Overcame the Loss of Water’s Protective Shield

Evaluating the Strength of a Hypothesis on How Terrestrial Organisms Overcame the Loss of Water’s Protective Shield Evaluating the Strength of a Hypothesis on How Terrestrial Organisms Overcame the Loss of Water’s Protective Shield Evaluating the Strength of a Hypothesis on How Terrestrial Organisms Overcame the Loss of Water’s Protective Shield Evaluating the Strength of a Hypothesis on How Terrestrial Organisms Overcame the Loss of Water’s Protective Shiel