58 research outputs found
Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy
- Author
- A Klungland
- A McArdle
- A McArdle
- A Umanskaya
- A Vasilaki
- A Vasilaki
- A Vasilaki
- AJ Janssen
- AL Wang
- AM Joseph
- AP Lightfoot
- AV Kuznetsov
- B Chabi
- B Cox
- B McDonagh
- B McDonagh
- CA Changou
- CS Broome
- D Bloemberg
- EJ Anderson
- EJ Anderson
- ET Chouchani
- FL Muller
- FL Muller
- G Gouspillou
- G Gouspillou
- GK Sakellariou
- GK Sakellariou
- GK Sakellariou
- GK Sakellariou
- H Chen
- H Degens
- HY Lee
- I Dimauro
- J Wanagat
- J Zielonka
- K Min
- KF Petersen
- KM Robinson
- KR Short
- L Wei-Lapierre
- M Picard
- M Picard
- MJ Morgan
- MM Porter
- MM Thomas
- MP Murphy
- MP Siegel
- MS Lustgarten
- MS Lustgarten
- O Miro
- P Mecocci
- R Pal
- R Sartori
- RJ Youle
- RL Goncalves
- S Melov
- S Petri
- SE Schriner
- SK Powers
- T Pearson
- VI Perez
- WA Irwin
- YC Jang
- Yiqiang Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/09/2016
- Field of study
Age-related loss of skeletal muscle mass and function is a major contributor to morbidity and has a profound effect on the quality of life of older people. The potential role of age-dependent mitochondrial dysfunction and cumulative oxidative stress as the underlying cause of muscle aging remains a controversial topic. Here we show that the pharmacological attenuation of age-related mitochondrial redox changes in muscle with SS31 is associated with some improvements in oxidative damage and mitophagy in muscles of old mice. However, this treatment failed to rescue the age-related muscle fiber atrophy associated with muscle atrophy and weakness. Collectively, these data imply that the muscle mitochondrial redox environment is not a key regulator of muscle fiber atrophy during sarcopenia but may play a key role in the decline of mitochondrial organelle integrity that occurs with muscle aging
Transcranial sonothrombolysis
- Publication venue
- 'Societas Neurologica Japonica'
- Publication date
- 01/01/2009
- Field of study
MR Findings of Spinal Muscular Atrophy Type II: Sibling Cases
- Author
- Publication venue
- 'Japanese Society for Magnetic Resonance in Medicine'
- Publication date
- 01/01/2003
- Field of study
Efficacy of A Fluoropyrimidine plus Mitomycin C in Pretreated Patients with Metastatic Colorectal Cancer Eligible for Regorafenib: A Retrospective Study
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- Zygulska AL Krzemieniecki K
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2017
- Field of study
A search for the common ground between Tic; Obsessive-compulsive and Autism Spectrum Disorders: part I, Tic disorders
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2017
- Field of study
Variability in the organic ligands released by <em>Emiliania huxleyi</em> under simulated ocean acidification conditions
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- Zondervan I
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2017
- Field of study
Recent progress on ceria doping and shaping strategies for solar thermochemical water and CO<sub>2</sub> splitting cycles
- Author
- Abanades S Flamant G
- Abanades S Le Gal A
- Abanades S Legal A, Cordier A, et al.
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- Esch F
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- Yang Z Woo TK, Hermansson K
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2019
- Field of study
Atomic and nuclear surface analysis methods for dental materials: A review
- Author
- Ahlberg M Akselsson R
- Aires MDM Treter J, Filho AN, et al.
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2018
- Field of study
Functions and Mechanisms of Sleep
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- Acuna-Goycolea C Li Y, Van Den Pol AN
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- Amzica F
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