Project 1 Analyzing Tumor Microenvironment and Exploiting its Characteristics in Search of Optimizing Cancer Therapy Including Neutron Capture Therapy (29P1)

In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2017/ProgRep2017.htmlPR1-1 Estimation of Therapeutic Effecicay of BCNT Based on the Intra- and Intercellular Heterogeneity in 10B Distribution /T. Sato and S. Masunga (29P1-1) [4]PR1-2 Design, Synthesis and Biological Evaluation of Pepducin-BSH Conjugates for BNCT /A. Isono et al. (29P1-2) [5]PR1-3 HIF-1 Maintains a Functional Relationship between Pancreatic Cancer Cells and Stromal Fibroblasts by Upregulating Expression and Secretion of Sonic Hedgehog /M. Kobayashi et al. (29P1-3) [6]PR1-4 Selective Accumulation of Boron-conjugated Liposomes Composed of Dimyristoylphosphatidylcholine to B16F10 MurineDimyristoylphosphatidylcholine to B16F10 Murine Melanoma Cells in Relation to Fluidity of Cell Membranes /S. Kasaoka et al. (29P1-5) [7]PR1-5 The Response of Cancer Cells after BNCR /L. Chen et al. (29P1-9) [8]PR1-6 Radiobiological Effect of Extracellular Boron Distribution and Neurton Irradiation /K. Nakai et al. (29P1-10) [9]PR1-7 Multilateral Approach toward Realization of Next Generation Boron Neutron Capture Therapy /Y. Matsumoto et al. (29P1-11) [10]PR1-8 Attempts to Sensitize Tumor Cells by Exploiting the Tumor Microenvironment /Y. Sanada and S. Masunaga (29P1-12) [11