The Different Nature in Seyfert 2 Galaxies With and Without Hidden Broad-Line Regions

We compile a large sample of 120 Seyfert 2 galaxies (Sy2s) which contains 49 hidden broad-line region (HBLR) Sy2s and 71 non-HBLR Sy2s. From the difference in the power sources between two groups, we test if HBLR Sy2s are dominated by active galactic nuclei (AGNs), and if non-HBLR Sy2s are dominated by starbursts. We show that: (1) HBLR Sy2s have larger accretion rates than non-HBLR Sy2s; (2) HBLR Sy2s have larger \Nev $\lambda 14.32$/\Neii $\lambda 12.81$ and \oiv $\lambda 25.89$/\Neii $\lambda 12.81$ line ratios than non-HBLR Sy2s; (3) HBLR Sy2s have smaller $IRAS$ $f_{60}/f_{25}$ flux ratio which shows the relative strength of the host galaxy and nuclear emission than non-HBLR Sy2s. So we suggest that HBLR Sy2s and non-HBLR Sy2s are AGN-dominated and starburst-dominated, respectively. In addition, non-HBLR Sy2s can be classified into the luminous ($L_{\rm [O III]}>10^{41} \rm ergs s^{-1}$) and less luminous ($L_{\rm [O III]}<10^{41} \rm ergs s^{-1}$) samples, when considering only their obscuration. We suggest that: (1) the invisibility of polarized broad lines (PBLs) in the luminous non-HBLR Sy2s depends on the obscuration; (2) the invisibility of PBLs in the less luminous non-HBLR Sy2s depends on the very low Eddington ratio rather than the obscuration.Comment: Accepted by ApJ, 11 pages, 4 figure

The Genetic Architecture of Diet-Induced Hepatic Fibrosis in Mice

We report the genetic analysis of a "humanized" hyperlipidemic mouse model for progressive nonalcoholic steatohepatitis (NASH) and fibrosis. Mice carrying transgenes for human apolipoprotein E*3-Leiden and cholesteryl ester transfer protein and fed a "Western" diet were studied on the genetic backgrounds of over 100 inbred mouse strains. The mice developed hepatic inflammation and fibrosis that was highly dependent on genetic background, with vast differences in the degree of fibrosis. Histological analysis showed features characteristic of human NASH, including macrovesicular steatosis, hepatocellular ballooning, inflammatory foci, and pericellular collagen deposition. Time course experiments indicated that while hepatic triglyceride levels increased steadily on the diet, hepatic fibrosis occurred at about 12 weeks. We found that the genetic variation predisposing to NASH and fibrosis differs markedly from that predisposing to simple steatosis, consistent with a multistep model in which distinct genetic factors are involved. Moreover, genome-wide association identified distinct genetic loci contributing to steatosis and NASH. Finally, we used hepatic expression data from the mouse panel and from 68 bariatric surgery patients with normal liver, steatosis, or NASH to identify enriched biological pathways. Conclusion: The pathways showed substantial overlap between our mouse model and the human disease

Superconductivity and Charge-density-wave-like Transition in Th2Cu4As5

We report the synthesis, crystal structure, and physical properties of a novel ternary compound, Th$_2$Cu$_4$As$_5$. The material crystallizes in a tetragonal structure with lattice parameters $a=4.0716(1)$ {\AA} and $c=24.8131(4)$ {\AA}. Its structure can be described as an alternating stacking of fluorite-type Th$_2$As$_2$ layers with antifluorite-type double-layered Cu$_4$As$_3$ slabs. The measurement of electrical resistivity, magnetic susceptibility and specific heat reveals that Th$_2$Cu$_4$As$_5$ undergoes bulk superconducting transition at 4.2 K. Moreover, all these physical quantities exhibit anomalies at 48 K, where the Hall coefficient change the sign. These findings suggest a charge-density-wave-like (CDW) transition, making Th$_2$Cu$_4$As$_5$ a rare example for studying the interplay between CDW and superconductivity.Comment: 11 pages, 6 figures, and 1 tabl