311 research outputs found
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Reducing defects through organizational learning within a Housing Association environment
Housing Associations (HAs) contribute circa 20% of the UK’s housing supply. HAs are however under increasing pressure as a result of funding cuts and rent reductions. Due to the increased pressure, a number of processes are currently being reviewed by HAs, especially how they manage and learn from defects. Learning from defects is considered a useful approach to achieving defect reduction within the UK housebuilding industry. This paper contributes to our understanding of how HAs learn from defects by undertaking an initial round table discussion with key HA stakeholders as part of an ongoing collaborative research project with the National House Building Council (NHBC) to better understand how house builders and HAs learn from defects to reduce their prevalence. The initial discussion shows that defect information runs through a number of groups, both internal and external of a HA during both the defects management process and organizational learning (OL) process. Furthermore, HAs are reliant on capturing and recording defect data as the foundation for the OL process. During the OL process defect data analysis is the primary enabler to recognizing a need for a change to organizational routines. When a need for change has been recognized, new options are typically pursued to design out defects via updates to a HAs Employer’s Requirements. Proposed solutions are selected by a review board and committed to organizational routine. After implementing a change, both structured and unstructured feedback is sought to establish the change’s success. The findings from the HA discussion demonstrates that OL can achieve defect reduction within the house building sector in the UK. The paper concludes by outlining a potential ‘learning from defects model’ for the housebuilding industry as well as describing future work
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Detecting defects in the UK new-build housing sector: a learning perspective
Rapid growth in the production of new homes in the UK is putting build quality under pressure as evidenced by an increase in the number of defects. Housing associations (HAs) contribute approximately 20% of the UK’s new housing supply. HAs are currently experiencing central government funding cuts and rental revenue reductions. As part of HAs’ quest to ramp up supply despite tight budget conditions, they are reviewing how they learn from defects. Learning from defects is argued as a means of reducing the persistent defect problem within the UK housebuilding industry, yet how HAs learn from defects is under-researched. The aim of this research is to better understand how HAs, in practice, learn from past defects to reduce the prevalence of defects in future new homes. The theoretical lens for this research is organizational learning. The results drawn from 12 HA case studies indicate that effective organizational learning has the potential to reduce defects within the housing sector. The results further identify that HAs are restricting their learning to focus primarily on reducing defects through product and system adaptations. Focusing on product and system adaptations alone suppresses HAs’ abilities to reduce defects in the future
Enhanced interlayer neutral excitons and trions in trilayer van der Waals heterostructures
Vertically stacked van der Waals heterostructures constitute a promising
platform for providing tailored band alignment with enhanced excitonic systems.
Here we report observations of neutral and charged interlayer excitons in
trilayer WSe2-MoSe2-WSe2 van der Waals heterostructures and their dynamics. The
addition of a WSe2 layer in the trilayer leads to significantly higher
photoluminescence quantum yields and tunable spectral resonance compared to its
bilayer heterostructures at cryogenic temperatures. The observed enhancement in
the photoluminescence quantum yield is due to significantly larger
electron-hole overlap and higher light absorbance in the trilayer
heterostructure, supported via first-principle pseudopotential calculations
based on spin-polarized density functional theory. We further uncover the
temperature- and power-dependence, as well as time-resolved photoluminescence
of the trilayer heterostructure interlayer neutral excitons and trions. Our
study elucidates the prospects of manipulating light emission from interlayer
excitons and designing atomic heterostructures from first-principles for
optoelectronics.Comment: 25 pages, 5 figures(Maintext). 9 pages, 7 figures(Supplementary
Information). - Accepted for publication in npg: 2D materials and
applications and reformatted to its standard. - Updated co-authors and
references. - Title and abstract are modified for clarity. - Errors have been
corrected, npg: 2D materials and applications (2018
On Safeguarding Privacy and Security in the Framework of Federated Learning
Motivated by the advancing computational capacity of wireless end-user
equipment (UE), as well as the increasing concerns about sharing private data,
a new machine learning (ML) paradigm has emerged, namely federated learning
(FL). Specifically, FL allows a decoupling of data provision at UEs and ML
model aggregation at a central unit. By training model locally, FL is capable
of avoiding data leakage from the UEs, thereby preserving privacy and security
to some extend. However, even if raw data are not disclosed from UEs,
individual's private information can still be extracted by some recently
discovered attacks in the FL architecture. In this work, we analyze the privacy
and security issues in FL, and raise several challenges on preserving privacy
and security when designing FL systems. In addition, we provide extensive
simulation results to illustrate the discussed issues and possible solutions.Comment: This paper has been accepted by IEEE Network Magazin
ATP-independent reversal of a membrane protein aggregate by a chloroplast SRP subunit
Membrane proteins impose enormous challenges to cellular protein homeostasis during their post-translational targeting, and they require chaperones to keep them soluble and translocation competent. Here we show that a novel targeting factor in the chloroplast signal recognition particle (cpSRP), cpSRP43, is a highly specific molecular chaperone that efficiently reverses the aggregation of its substrate proteins. In contrast to 'ATPases associated with various cellular activities' (AAA+) chaperones, cpSRP43 uses specific binding interactions with its substrate to mediate its 'disaggregase' activity. This disaggregase capability can allow targeting machineries to more effectively capture their protein substrates and emphasizes a close connection between protein folding and trafficking processes. Moreover, cpSRP43 provides the first example to our knowledge of an ATP-independent disaggregase and shows that efficient reversal of protein aggregation can be attained by specific binding interactions between a chaperone and its substrate
Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs
This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited
Psychological distress among re-education through labour camp detainees in Guangxi Autonomous Region, China
There is currently no information about the prevalence of, and factors contributing to psychological distress experienced by re-education through labour camp detainees in China. [Methods:] A cross-sectional face-to-face survey was conducted in three labour camps in Guangxi, China. The questionnaire covered socio-demographic characteristics; sexually transmissible infections (STIs); drug use; psychological distress (K-10); and health service usage and access inside the labour camps. K-10 scores were categorised as ≤30 (low to moderate distress) and >30 or more (highly distressed). Univariate and multivariate logistic regression models identified factors independently associated with high K-10 scores for men and women separately. [Results:] In total, 755 detainees, 576 (76%) men and 179 (24%) women, participated in the health survey. The study found 11.6% men versus 11.2% women detainees experienced high psychological distress, but no significant gender differences were observed (p> 0.05). Multivariate logistic regression showed that multiple physical health problems were significantly associated with high psychological distress among men. [Conclusion:] Drug treatment and forensic mental health services need to be established in detention centres in China to treat more than 10% of detainees with drug use and mental health disorders
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Learning from defects in the UK housing sector using action research: a case study of a housing association
Purpose: Maximising the benefit of learning from defects is regarded by UK housing associations (HAs) as a key opportunity to meet their challenges of building more homes with reduced government funding and rent incomes. Despite learning from defects being a frequent recommendation to reduce defects in the construction literature, there is scarce empirical evidence into how HAs actually learn from defects. This research aims to better understand how HAs learn from past defects and induce change to reduce defects.
Design/methodology/approach: Guided by organisational learning (OL) as the theoretical lens, a 21-month action research (AR) project explored one HA’s defects management and learning processes.
Findings: OL has the potential to reduce defects in new homes but is a secondary task which is reliant on a defects management team analysing defect data to identify priority areas. As such, learning from defects can be reduced due to peaks in workload if data analysis is a manual process. . Furthermore, a dual learning approach plays a significant role for HA’s learning consisting of designing out defects (codification) supported by networking (personalisation) to tackle issues of workmanship on site and those defects that cannot be designed out.
Originality/value: This study demonstrates OL has the potential to reduce defects in new homes but is a secondary task in HA’s practice; and highlights the practical challenges of academia and industry co-production in AR in construction
Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose
Chiral recognition remains a major challenge in the area of molecular receptor design. With this research, we set out to explore the use of proline-based receptors for chiral recognition. Importantly, the proline structure allows for the introduction of at least two different binding groups due to the availability of both an amine and carboxylic acid group. Here we report a proof-of-concept exploration into the chiral recognition of d/l-glucose as a model chiral species, which prefers to bind to at least two boronic acid groups. We evaluated several proline-based receptors incorporating two phenylboronic acid groups, respectively, at the N- and C-termini of the amino acid residue, via amide bonds. We confirmed that the receptors exhibited chiral recognition using CD, 1H NMR, and 19F NMR spectroscopy. Given the derivation diversity available, our strategy to use proline-based receptors for chiral recognition holds significant promise for extension to other chiral systems. </p
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