Usage-Based and Universal Grammar-Based Approaches to Second Language Acquisition

The theoretical controversy that surrounds the acquisition of a second or foreign language is seemingly unending. Though there are dissensions in the literature, past studies had indicated that scholars tended to fall into two groups of schools of thought, the usage-based and the universal grammar-based approaches in second language acquisition. This paper reviews the literature of recently published findings in scholarly papers and contrasted the varied views of how second language can be acquired. Empirical evidence of both views are contrasted and discussed. Included in the discussion are environmental variables such as types of input and the length of input and non-environmental variables that are innate in learners

Role of formal input exposure and onset age in grammaticality judgement

This study examines the effects of formal input exposure and the onset age of exposure on the performance of eleven different morphosyntactic structures in a foreign language setting. It studies whether being exposed to longer hours of formal language classes at a younger age is advantageous for Iranian EFL learners. Some studies have claimed that there is no advantage for early starters and in the field of grammatical learning, later starters perform better. Four groups of Iranian learners with different formal learning times participated in this study: Groups A and B were public and private school students, respectively, whereas Groups C and D had extra supplementary classes at language institutes as well. A Grammaticality Judgement Task (GJT) including some grammatical structures which were claimed to be problematic for EFL learners, was used as a tool to determine the possible differences in the performance of grammatical structures of the four groups. A two-way ANCOVA and a one-way ANOVA were used to analyse the data. Results suggest that long hours of formal exposure lead to better grammatical performance and the participants who started learning English at age 9 or below performed better in the GJT

The temporal role in grammatical performance of foreign language learners of English

This study evaluates the effects of length of formal learning time on the grammatical performance of English morphosyntactic structures among Iranian foreign language learners. Among different factors affecting language learning, the length of formal language exposure or language input is introduced as an important factor in language learning process. Thus, length of receiving input exposure in the form of formal classroom instruction in the current study is carefully studied by categorizing the participants in four different groups. The participants represented different exposure time groups by having various formal instruction hours at school and/or language center. In order to investigate the role of formal learning time on the performance of the individual morphosyntactic structures, the participants were presented to a timed Grammaticality Judgment Task. The task tested eleven different morphosyntactic structures and contained 132 sentences. The participants were asked to judge the grammaticality of the sentences and do the necessary corrections if needed. Repeated Measures ANOVA and regression analyses were performed to analyse the data. Results revealed the contribution of time on the performance of the individual structures

Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives

Gastroenteropancreatic neuroendocrine tumours (GEP NETs) are rare tumours that present many clinical features

Predictive factors of antiproliferative activity of octreotide LAR as first-line therapy for advanced neuroendocrine tumours

background: The antiproliferative activity of octreotide LAR in neuroendocrine tumours (NETs) has been demonstrated by small retrospective studies and confirmed by a prospective phase III trial (PROMID). However, there are limited data about the duration and predictors of response. The aim of our retrospective study was to determine the time to radiological progression (TTRP) of disease and the factors that were associated with better response. methods: A total of 254 treatment naïve patients with advanced NETs and positive somatostatin receptor scintigraphy were included. Mean follow-up period was 42 months. results: The location of primary was in the small bowel in 204, pancreas in 22, lungs in 14, rectum in 7 and unknown in 7 patients. Most tumours were well-differentiated, G1 (58%) and G2 (23%). The majority of patients commenced octreotide LAR due to functional symptoms (57%), radiological progression (10%) or in the presence of asymptomatic and stable disease on the basis of data from the PROMID trial (18.5%). Partial response occurred in 5%. For all patients, the median TTRP was 37 months (95% confidence interval, CI: 32–52 months). There was a statistically significant shorter TTRP in patients with pancreatic tumours, liver metastases and intermediate grade tumours. Extremely raised (>10 times the upper limit of normal) baseline chromogranin A levels were associated with an unfavourable outcome. In contrast, male sex, carcinoid heart disease and initiation of treatment in the presence of stable disease were predictive of a better response. Age, extra-hepatic metastases, presence of mesenteric desmoplasia, previous resection and functional status of the primary tumour did not affect response. conclusions: The duration of the antiproliferative effect of octreotide LAR seems to be longer than previously reported. This study has identified several predictors of response in a large cohort of patients with NETs on somatostatin analogue therapy