647 research outputs found
Random matrix models with log-singular level confinement: method of fictitious fermions
Joint distribution function of N eigenvalues of U(N) invariant random-matrix
ensemble can be interpreted as a probability density to find N fictitious
non-interacting fermions to be confined in a one-dimensional space. Within this
picture a general formalism is developed to study the eigenvalue correlations
in non-Gaussian ensembles of large random matrices possessing non-monotonic,
log-singular level confinement. An effective one-particle Schroedinger equation
for wave-functions of fictitious fermions is derived. It is shown that
eigenvalue correlations are completely determined by the Dyson's density of
states and by the parameter of the logarithmic singularity. Closed analytical
expressions for the two-point kernel in the origin, bulk, and soft-edge scaling
limits are deduced in a unified way, and novel universal correlations are
predicted near the end point of the single spectrum support.Comment: 13 pages (latex), Presented at the MINERVA Workshop on Mesoscopics,
Fractals and Neural Networks, Eilat, Israel, March 199
Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection
Background
One of the most effective prophylactic strategies against periprosthetic joint infection (PJI) is administration of perioperative antibiotics. Many orthopedic surgeons are unaware of the weight-based dosing protocol for cefazolin. This study aimed at elucidating what proportion of patients receiving cefazolin prophylaxis are underdosed and whether this increases the risk of PJI.
Methods
A retrospective study of 17,393 primary total joint arthroplasties receiving cefazolin as perioperative prophylaxis from 2005 to 2017 was performed. Patients were stratified into 2 groups (underdosed and adequately dosed) based on patient weight and antibiotic dosage. Patients who developed PJI within 1 year following index procedure were identified. A bivariate and multiple logistic regression analyses were performed to control for potential confounders and identify risk factors for PJI.
Results
The majority of patients weighing greater than 120 kg (95.9%, 944/984) were underdosed. Underdosed patients had a higher rate of PJI at 1 year compared with adequately dosed patients (1.51% vs 0.86%, P = .002). Patients weighing greater than 120 kg had higher 1-year PJI rate than patients weighing less than 120 kg (3.25% vs 0.83%, P < .001). Patients who were underdosed (odds ratio, 1.665; P = .006) with greater comorbidities (odds ratio, 1.259; P < .001) were more likely to develop PJI at 1 year.
Conclusion
Cefazolin underdosing is common, especially for patients weighing more than 120 kg. Our study reports that underdosed patients were more likely to develop PJI. Orthopedic surgeons should pay attention to the weight-based dosing of antibiotics in the perioperative period to avoid increasing risk of PJI
Total Widths And Slopes From Complex Regge Trajectories
Maximally complex Regge trajectories are introduced for which both Re
and Im grow as ( small and
positive). Our expression reduces to the standard real linear form as the
imaginary part (proportional to ) goes to zero. A scaling formula for
the total widths emerges: constant for large M, in very
good agreement with data for mesons and baryons. The unitarity corrections also
enhance the space-like slopes from their time-like values, thereby resolving an
old problem with the trajectory in charge exchange. Finally, the
unitarily enhanced intercept, , \nolinebreak is in
good accord with the Donnachie-Landshoff total cross section analysis.Comment: 9 pages, 3 Figure
Two-band random matrices
Spectral correlations in unitary invariant, non-Gaussian ensembles of large
random matrices possessing an eigenvalue gap are studied within the framework
of the orthogonal polynomial technique. Both local and global characteristics
of spectra are directly reconstructed from the recurrence equation for
orthogonal polynomials associated with a given random matrix ensemble. It is
established that an eigenvalue gap does not affect the local eigenvalue
correlations which follow the universal sine and the universal multicritical
laws in the bulk and soft-edge scaling limits, respectively. By contrast,
global smoothed eigenvalue correlations do reflect the presence of a gap, and
are shown to satisfy a new universal law exhibiting a sharp dependence on the
odd/even dimension of random matrices whose spectra are bounded. In the case of
unbounded spectrum, the corresponding universal `density-density' correlator is
conjectured to be generic for chaotic systems with a forbidden gap and broken
time reversal symmetry.Comment: 12 pages (latex), references added, discussion enlarge
Vector Continued Fractions using a Generalised Inverse
A real vector space combined with an inverse for vectors is sufficient to
define a vector continued fraction whose parameters consist of vector shifts
and changes of scale. The choice of sign for different components of the vector
inverse permits construction of vector analogues of the Jacobi continued
fraction. These vector Jacobi fractions are related to vector and scalar-valued
polynomial functions of the vectors, which satisfy recurrence relations similar
to those of orthogonal polynomials. The vector Jacobi fraction has strong
convergence properties which are demonstrated analytically, and illustrated
numerically.Comment: Published form - minor change
Generating GHZ state in 2m-qubit spin network
We consider a pure 2m-qubit initial state to evolve under a particular
quantum me- chanical spin Hamiltonian, which can be written in terms of the
adjacency matrix of the Johnson network J(2m;m). Then, by using some techniques
such as spectral dis- tribution and stratification associated with the graphs,
employed in [1, 2], a maximally entangled GHZ state is generated between the
antipodes of the network. In fact, an explicit formula is given for the
suitable coupling strengths of the hamiltonian, so that a maximally entangled
state can be generated between antipodes of the network. By using some known
multipartite entanglement measures, the amount of the entanglement of the final
evolved state is calculated, and finally two examples of four qubit and six
qubit states are considered in details.Comment: 22 page
Generating Bounds for the Ground State Energy of the Infinite Quantum Lens Potential
Moment based methods have produced efficient multiscale quantization
algorithms for solving singular perturbation/strong coupling problems. One of
these, the Eigenvalue Moment Method (EMM), developed by Handy et al (Phys. Rev.
Lett.{\bf 55}, 931 (1985); ibid, {\bf 60}, 253 (1988b)), generates converging
lower and upper bounds to a specific discrete state energy, once the signature
property of the associated wavefunction is known. This method is particularly
effective for multidimensional, bosonic ground state problems, since the
corresponding wavefunction must be of uniform signature, and can be taken to be
positive. Despite this, the vast majority of problems studied have been on
unbounded domains. The important problem of an electron in an infinite quantum
lens potential defines a challenging extension of EMM to systems defined on a
compact domain. We investigate this here, and introduce novel modifications to
the conventional EMM formalism that facilitate its adaptability to the required
boundary conditions.Comment: Submitted to J. Phys.
Generating Converging Bounds to the (Complex) Discrete States of the Hamiltonian
The Eigenvalue Moment Method (EMM), Handy (2001), Handy and Wang (2001)) is
applied to the Hamiltonian, enabling
the algebraic/numerical generation of converging bounds to the complex energies
of the states, as argued (through asymptotic methods) by Delabaere and
Trinh (J. Phys. A: Math. Gen. {\bf 33} 8771 (2000)).Comment: Submitted to J. Phys.
A Convergent Method for Calculating the Properties of Many Interacting Electrons
A method is presented for calculating binding energies and other properties
of extended interacting systems using the projected density of transitions
(PDoT) which is the probability distribution for transitions of different
energies induced by a given localized operator, the operator on which the
transitions are projected. It is shown that the transition contributing to the
PDoT at each energy is the one which disturbs the system least, and so, by
projecting on appropriate operators, the binding energies of equilibrium
electronic states and the energies of their elementary excitations can be
calculated. The PDoT may be expanded as a continued fraction by the recursion
method, and as in other cases the continued fraction converges exponentially
with the number of arithmetic operations, independent of the size of the
system, in contrast to other numerical methods for which the number of
operations increases with system size to maintain a given accuracy. These
properties are illustrated with a calculation of the binding energies and
zone-boundary spin- wave energies for an infinite spin-1/2 Heisenberg chain,
which is compared with analytic results for this system and extrapolations from
finite rings of spins.Comment: 30 pages, 4 figures, corrected pd
Lyapunov exponent and natural invariant density determination of chaotic maps: An iterative maximum entropy ansatz
We apply the maximum entropy principle to construct the natural invariant
density and Lyapunov exponent of one-dimensional chaotic maps. Using a novel
function reconstruction technique that is based on the solution of Hausdorff
moment problem via maximizing Shannon entropy, we estimate the invariant
density and the Lyapunov exponent of nonlinear maps in one-dimension from a
knowledge of finite number of moments. The accuracy and the stability of the
algorithm are illustrated by comparing our results to a number of nonlinear
maps for which the exact analytical results are available. Furthermore, we also
consider a very complex example for which no exact analytical result for
invariant density is available. A comparison of our results to those available
in the literature is also discussed.Comment: 16 pages including 6 figure
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