250 research outputs found

    Distributed computing building blocks for rational agents

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    Following [4] we extend and generalize the game-theoretic model of distributed computing, identifying different utility functions that encompass different potential preferences of players in a distributed system. A good distributed algorithm in the game-theoretic context is one that prohibits the agents (processors with interests) from de-viating from the protocol; any deviation would result in the agent losing, i.e., reducing its utility at the end of the algorithm. We dis-tinguish between different utility functions in the context of dis-tributed algorithms, e.g., utilities based on communication prefer-ence, solution preference, and output preference. Given these pref-erences we construct two basic building blocks for game theoretic distributed algorithms, a wake-up building block resilient to any preference and in particular to the communication preference (to which previous wake-up solutions were not resilient), and a knowl-edge sharing building block that is resilient to any and in partic-ular to solution and output preferences. Using the building blocks we present several new algorithms for consensus, and renaming as well as a modular presentation of the leader election algorithm of [4]

    Hypermatrix factors for string and membrane junctions

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    The adjoint representations of the Lie algebras of the classical groups SU(n), SO(n), and Sp(n) are, respectively, tensor, antisymmetric, and symmetric products of two vector spaces, and hence are matrix representations. We consider the analogous products of three vector spaces and study when they appear as summands in Lie algebra decompositions. The Z3-grading of the exceptional Lie algebras provide such summands and provides representations of classical groups on hypermatrices. The main natural application is a formal study of three-junctions of strings and membranes. Generalizations are also considered.Comment: 25 pages, 4 figures, presentation improved, minor correction

    Magneto-caloric effect in the pseudo-binary intermetallic YPrFe17 compound

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    We have synthesized the intermetallic YPrFe17 compound by arc-melting. X-ray and neutron powder diffraction show that the crystal structure is rhombohedral with View the MathML source space group (Th2Zn17-type). The investigated compound exhibits a broad isothermal magnetic entropy change {\Delta}SM(T) associated with the ferro-to-paramagnetic phase transition (TC \approx 290 K). The |{\Delta}SM| (\approx 2.3 J kg-1 K-1) and the relative cooling power (\approx 100 J kg-1) have been calculated for applied magnetic field changes up to 1.5 T. A single master curve for {\Delta}SM under different values of the magnetic field change can be obtained by a rescaling of the temperature axis. The results are compared and discussed in terms of the magneto-caloric effect in the isostructural R2Fe17 (R = Y, Pr and Nd) binary intermetallic alloys.Comment: Preprint, 5 pages (postprint), 4 figures, regular pape

    Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry

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    Aim of this study was the site-specific conjugation of an epidermal growth factor (EGF)-polyethylene glycol (PEG) chain by click chemistry onto a poly(amido amine) (PAMAM) dendron, as a key step toward defined multifunctional carriers for targeted gene delivery. For this purpose, at first propargyl amine cored PAMAM dendrons with ester ends were synthesized. The chain terminal ester groups were then modified by oligoamines with different secondary amino densities. The oligoamine-modified PAMAM dendrons were well biocompatible, as demonstrated in cytotoxicity assays. Among the different oligoamine-modified dendrons, PAMAM-pentaethylenehexamine (PEHA) dendron polyplexes displayed the best gene transfer ability. Conjugation of PAMAM-PEHA dendron with PEG spacer was conducted via click reaction, which was performed before amidation with PEHA. The resultant PEG-PAMAM-PEHA copolymer was then coupled with EGF ligand. pDNA transfections in HuH-7 hepatocellular carcinoma cells showed a 10-fold higher efficiency with the polyplexes containing conjugated EGF as compared to the ligand-free ones, demonstrating the concept of ligand targeting. Overall gene transfer efficiencies, however, were moderate, suggesting that additional measures for overcoming subsequent intracellular bottlenecks in delivery have to be taken

    Frequency Locking of an Optical Cavity using LQG Integral Control

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    This paper considers the application of integral Linear Quadratic Gaussian (LQG) optimal control theory to a problem of cavity locking in quantum optics. The cavity locking problem involves controlling the error between the laser frequency and the resonant frequency of the cavity. A model for the cavity system, which comprises a piezo-electric actuator and an optical cavity is experimentally determined using a subspace identification method. An LQG controller which includes integral action is synthesized to stabilize the frequency of the cavity to the laser frequency and to reject low frequency noise. The controller is successfully implemented in the laboratory using a dSpace DSP board.Comment: 18 pages, 9 figure

    A method to design job rotation schedules to prevent work-related musculoskeletal disorders in repetitive work

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    This is an Accepted Manuscript of an article published by Taylor & Francis Group in International Journal of Production Research in 2012, available online: http://www.tandfonline.com/10.1080/00207543.2011.653452.Job rotation is an organisational strategy widely used in human-based production lines with the aim of preventing work-related musculoskeletal disorders (WMSDs). These work environments are characterised by the presence of a high repetition of movements, which is a major risk factor associated with WMSDs. This article presents a genetic algorithm to obtain rotation schedules aimed at preventing WMSDs in such environments. To do this, it combines the effectiveness of genetic algorithms optimisation with the ability to evaluate the presence of risk by repeated movements by following the OCRA ergonomic assessment method. The proposed algorithm can design solutions in which workers will switch jobs with high repeatability of movements with other less demanding jobs that support their recovery. In addition, these solutions are able to diversify the tasks performed by workers during the day, consider their disabilities and comply with restrictions arising from the work organisation.The authors wish to thank the Universitat Politecnica de Valencia which supported this research through its Program for the Support of Research and Development 2009 and its financing through the project PAID-06-09/2902.Asensio Cuesta, S.; Diego-Mas, JA.; Cremades Oliver, L.; González-Cruz, M. (2012). A method to design job rotation schedules to prevent work-related musculoskeletal disorders in repetitive work. International Journal of Production Research. 50(24):7467-7478. https://doi.org/10.1080/00207543.2011.653452S74677478502

    Quantifier scope in sentence prosody? : A view from production

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    Logical scope interpretation and sentence prosody exhibit intricate, yet scarcely studied interrelations across a variety of languages and constructions. Despite these observable interrelations, it is not clear whether quantifier scope by itself is able to directly affect prosodic form. Information structure is a key potential confounding factor, as it appears to richly interact both with scope interpretation and with prosodic form. To address this complication, the current study investigates, based on data from Hungarian, whether quantifier scope is expressed prosodically if information structure is kept in check. A production experiment is presented that investigates grammatically scope ambiguous doubly quantified sentences with varied focus structures, while lacking a syntactically marked topic or focus. In contrast to the information structural manipulation, which is manifest in the analysis of the acoustic data, the results reveal no prosodic effect of quantifier scope, nor the interaction of scope with information structure. This finding casts doubt on the notion that logical scope can receive direct prosodic expression, and it indirectly corroborates the restrictive view instead that scope interpretation is encoded in prosody only in cases in which it is a free rider on information structure

    Development and Implementation of a Registry of Patients Attending Multidisciplinary Pain Treatment Clinics: The Quebec Pain Registry

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    The Quebec Pain Registry (QPR) is a large research database of patients suffering from various chronic pain (CP) syndromes who were referred to one of five tertiary care centres in the province of Quebec (Canada). Patients were monitored using common demographics, identical clinical descriptors, and uniform validated outcomes. This paper describes the development, implementation, and research potential of the QPR. Between 2008 and 2013, 6902 patients were enrolled in the QPR, and data were collected prior to their first visit at the pain clinic and six months later. More than 90% of them (mean age ± SD: 52.76 ± 4.60, females: 59.1%) consented that their QPR data be used for research purposes. The results suggest that, compared to patients with serious chronic medical disorders, CP patients referred to tertiary care clinics are more severely impaired in multiple domains including emotional and physical functioning. The QPR is also a powerful and comprehensive tool for conducting research in a “real-world” context with 27 observational studies and satellite research projects which have been completed or are underway. It contains data on the clinical evolution of thousands of patients and provides the opportunity of answering important research questions on various aspects of CP (or specific pain syndromes) and its management
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