The first case of hairworm, Gordius sp. vomited from a domestic dog in Japan

An adult female hairworm was vomited from a domestic dog with a cough in Hiroshima Prefecture. The worm body was long and slender, measuring 42.5 cm in length and 1 mm in maximum width. The specimen showed microscopically the smooth cuticular without tuberculations. This case is the first record of Gordius sp. infection in a dog in Japan

Increase in cell surface wheat germ agglutinin binding in a rat hepatoma cell line dRLa 74 treated with concanavalin A.

Wheat germ agglutinin binding to a rat hepatoma cell line dRLa 74 treated with concanavalin A was studied. It increased depending on the concanavalin A concentration in the culture medium. The cells exhibited about twofold increase in wheat germ agglutinin-binding when pretreated with 50 micrograms/ml of concanavalin A for 48 h. The wheat germ agglutinin binding sites were shown to be localized at the cell surface by lectin-histochemistry. Wheat germ agglutinin blotting of microsomal membrane proteins showed a broad wheat germ agglutinin-reactive band with an apparent molecular weight of 90 to 100 kDa. Loss of wheat germ agglutinin binding to dRLa 74 cells and the glycoprotein after neuraminidase treatment suggested that wheat germ agglutinin reacted with cell surface sialyl residues of dRLa 74 cells. The induced change was reversible. Increased wheat germ agglutinin binding returned to the pretreatment level when the concanavalin A-treated cells were subcultured in the absence of concanavalin A. These observations suggest that environmental factors interacting with tumor cell surface sugar moieties may induce reversible epigenetic changes on cell surface carbohydrate structures.</p

Takafuta-Tsukatani Mounded Tomb, Jinseki-kōgen Town, Hiroshima Prefecture

Takafuta-Tsukatani mounded tomb (kofun) was located in Jinseki-kōgen Town, Hiroshima Prefecture. However, immediately after World War II the site was reclaimed as farmland and the mound disappeared. In 2010, some of the finds unearthed by the landowner of the tomb were donated to Jinseki-kōgen Town. Furthermore, other relics from the Takafuta-Tsukatani mounded tomb were also held at the Hiroshima Prefectural Fuchū High School, but are now in the possession of the Hiroshima Prefectural Museum of History. In this article, all unearthed finds are presented in their entirety. Takafuta-Tsukatani mounded tomb was built during the Late Kofun period (latter half of the 6th century A.D.). Many objects were unearthed, including iron swords, a hand guard of a sword (tsuba), horse bits (kutsuwa), stirrups (abumi), beads of necklaces, Haji ware (hajiki), and Sue ware (sueki). In particular, horse bits with gourd-shaped iron rings (hisagogata kanjō kagami itatsuki kutsuwa) are characteristic for mounded tombs in the Kibi region (ancient province consisting of Okayama Prefecture and the eastern part of Hiroshima Prefecture). In the latter half of the 6th century the first iron manufacture sites appeared in the Bingo region (eastern part of Hiroshima Prefecture). It is highly probable that the person buried in the Takafuta-Tsukatani mounded tomb was involved in horse harness and trappings production, iron manufacture and blacksmithing unique to the Kibi region.今回の資料紹介は2018・2019年度大学院文学研究科考古学研究室の資料実習授業における遺物観察･実測、写真撮影をもとにし、神石高原町の委託研究費を一部使用した

遠位弓部大動脈瘤肺動脈穿破

We report an extremely rare case of rupture of an aortic arch aneurysm into the pulmonary artery. An 85-year-old man was visited to our hospital for surgical repair of aortic arch aneurysm. After arrived at hospital, we noticed he suffer from severe congestive heart failure. Chest auscultation indicated Levine III/IV continuous heart murmur. Computed tomography revealed aortic arch aneurysm and aortic dissection of ascending aorta. Echocardiography demonstrated an abnormal shunt flow from aortic arch aneurysm into the pulmonary artery. At surgery, total arch replacement and pulmonary artery reconstruction were performed

Assistência de enfermagem a paciente com diabetes mellitus gestacional: uma revisão de literatura

The aim was to analyze the evidence in the literature about nursing care in Primary Care for patients who had Gestational Diabetes Mellitus. This is an integrative literature review, the selected databases were: PubMed, SciELO and the VHL database platform. The following descriptors were used: Diabetes, Gestational; Nursing Care; Primary Health Care and Public Health. The research resulted in 325 works, after reading only 11 articles were selected, which were classified into four categories, namely: Understanding the potential of care; identifying the factors that affect the results; Capacity building/training/knowledge; Weaknesses of care. It is concluded that the management of patients with gestational diabetes mellitus in Primary Care becomes extremely relevant for reducing maternal-fetal complications as well as for decreasing the incidence of progression to type 2 diabetes.Objetivou-se analisar as evidências na literatura sobre a assistência de enfermagem na Atenção Básica a paciente que apresentaram o Diabetes Mellitus Gestacional. Trata-se de uma revisão integrativa de literatura, as bases de dados selecionadas foram: PubMed, SciELO e a plataforma de base de dados BVS. Os seguintes descritores foram utilizados: Diabetes, Gestational; Nursing Care; Primary Health Care e Public Health. Resultou-se das pesquisas 325 obras, após a leitura foram selecionados apenas 11 artigos, que foram classificados em quatro categoria, são elas: Compreendendo as potencialidades do cuidado; identificando os fatores que interferem nos resultados; Capacitação/treinamento/conhecimento; Fragilidades do cuidado.  Conclui-se que o manejo em pacientes com diabetes mellitus gestacional na Atenção Básica torna-se extremamente relevante para a diminuição das complicações materno-fetais como também na diminuição da incidência da progressão para a diabetes tipo 2

遠位弓部大動脈瘤肺動脈穿破

We report an extremely rare case of rupture of an aortic arch aneurysm into the pulmonary artery. An 85-year-old man was visited to our hospital for surgical repair of aortic arch aneurysm. After arrived at hospital, we noticed he suffer from severe congestive heart failure. Chest auscultation indicated Levine III/IV continuous heart murmur. Computed tomography revealed aortic arch aneurysm and aortic dissection of ascending aorta. Echocardiography demonstrated an abnormal shunt flow from aortic arch aneurysm into the pulmonary artery. At surgery, total arch replacement and pulmonary artery reconstruction were performed

Microbiome composition comparison in oral and atherosclerotic plaque from patients with and without periodontitis

There is no conclusive evidence regarding a causal relationship between periodontitis and atherosclerosis. In this study, we examined the microbiome in the oral cavity and atheromatous plaques from atherosclerosis patients with or without periodontitis to investigate the role of oral bacteria in the formation of atheromatous plaques. We chose four patients with and without periodontitis, who had undergone carotid endarterectomy. Bacterial samples were extracted from the tongue surface, from periodontal pocket (during the oral examination), and from the atheromatous plaques (APs). We investigated the general and oral conditions from each patient and performed next-generation sequencing (NGS) analysis for all bacterial samples. There were no significant differences between both groups concerning general conditions. However, the microbiome patterns of the gingival pocket showed differences depending on the absence or presence of periodontitis, while those of the tongue surface were relatively similar. The microbiome pattern of the atheromatous plaques was entirely different from that on the tongue surface and gingival pocket, and oral bacteria were seldom detected. However, the microbiome pattern in atheromatous plaques was different in the presence or absence of periodontitis. These results suggested that oral bacteria did not affect the formation of atheromatous plaques directly

チアノーゼ性心疾患に対する肺動脈絞扼術

The early and late results of pulmonary artery banding (PAB) for cyanotic heart defects in early infancy were reviewed. Nine patients were divided into two groups : Group F (five patiens) in which Fontan type repairs were expected as definitive repair in the near future ; Group A (four patients) in which anatomical repairs were programmed in the near future. Six patients had a good early postoperative course, and then consisted of three patients of Group A and three patients of Group F. The band circumference, intraoperative pulmonary-to-systemic systolic pressure ratio and arterial oxygen tension after PAB in the good cases of Group A were 20.0±1.7 mm + 1 mm for each kilogram of the infant's weight, 0.52±0.07 and 46.4±11.3 mmHg respectively. These indices in the good cases of Group F were 21.1±1.7 mm + 1 mm for each kilogram of the infant's weight, 0.55±0.02 and 38.8±1.0 mmHg respectively. The standard deviations of every index for PAB in Group F were small. Three patients of Group A have undergone successful total correction. Intraoperative pulmonary-to-systemic systolic pressure ratio of 0.5 as the index of PAB is preferable to Group A. However, only two patient of Group F were waiting for Fontan type definitive repair. For the patient especially in Group F, careful observation and well-timed staged repair with regard to subaortic stenosis and restrictive atrial septal defect and ventricular septal defect are necessary after accurate PAB as mentioned above