526 research outputs found

    Human Being Emotion in Cognitive Intelligent Robotic Control Pt I: Quantum / Soft Computing Approach

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    Abstract. The article consists of two parts. Part I shows the possibility of quantum / soft computing optimizers of knowledge bases (QSCOptKB™) as the toolkit of quantum deep machine learning technology implementation in the solution’s search of intelligent cognitive control tasks applied the cognitive helmet as neurointerface. In particular, case, the aim of this part is to demonstrate the possibility of classifying the mental states of a human being operator in on line with knowledge extraction from electroencephalograms based on SCOptKB™ and QCOptKB™ sophisticated toolkit. Application of soft computing technologies to identify objective indicators of the psychophysiological state of an examined person described. The role and necessity of applying intelligent information technologies development based on computational intelligence toolkits in the task of objective estimation of a general psychophysical state of a human being operator shown. Developed information technology examined with special (difficult in diagnostic practice) examples emotion state estimation of autism children (ASD) and dementia and background of the knowledge bases design for intelligent robot of service use is it. Application of cognitive intelligent control in navigation of autonomous robot for avoidance of obstacles demonstrated.

    Features of superexchange nonresonant tunneling conductance in anchored molecular wires

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    NAS Ukraine via Project No. 0116U002067A modified superexchange model is used to clarify the physical mechanisms for the formation of nonresonant tunneling conductance in terminated molecular wires. Due to the specific relationship between its key parameters, this model has wider areas of applicability compared to the flat-barrier model and the standard superexchange model, which are widely involved for the physical interpretation of experimental results. Moreover, the results obtained in the two latest models appear in the modified model as characteristic limiting cases. Our estimates show that the exponential decay of conductance, characterized by an attenuation factor β (per repeating unit), is limited by the conditions β ≤ 1.2 and β ≥ 3.7 for the flat-barrier and standard models, respectively. At the same time, the modified superexchange model yields β > 0, which, thus, allows us to analyze the tunneling conductance in molecular wires containing both saturated and conjugated bonds. We also show that for a small number of N repeating wire units (about 3-6 depending on the value of β), the exponential dependence of conductance on N is violated and, accordingly, contact conductance is not identical to conductance at N = 0. Formulas are found which, on the basis of experimental data, make it possible to establish the values of superexchange parameters as well as indicate the conditions of possible hybridization between the orbitals of the anchor groups and the adjacent end units belonging to the interior wire region. One example is the establishment of features in the tunneling conductance of terminated alkane chains caused by the nature of their anchor groups.publishersversionpublishe

    ARCHITECTURAL MODELLING OF “SOUND” PERGOLA

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    The article describes architectural solutions of pergolas adapted for the reproduction of synthesized acoustic space. The solution is represented by means of computer modelling and visualizes both processes and ob-jects on the example of construction and calculations. The project design of architectural models is an integral part in the practical reconstruction of the geospatial space studied by the architectural geography

    Cr, Co and rare earth elements systematics in ice-rafted sediments of northern part of the Beaufort gyre

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    The results of analysis of the systematics of Cr, Co and rare earth elements (REE) in ice-rafted sediments (IRS) of the northern part of the Beaufort Cycle (Arctic Ocean) are considered in the article. The IRS was assembled on the ARK-XIV-1/a cruise of the NIS Polarstern in 1998. The exact position of the sources of the IRS present in the ice has not been established to date. This is due, on the one hand, to the complex ice cycle in the Arctic Basin, on the other - a relatively small amount of data on the actual composition of the IRS. According to the views of most researchers, the main IRS supplier is the wide and shallow Siberian Arctic shelf. In the Beaufort Sea, the distinctive features of which are a much narrower shelf and almost constant presence of ice in the summer period, the conditions for the formation of the IRS are not so favorable. The contents of rare and scattered elements in the IRS samples were determined with the help of INAA at GEOKHI RAS. As a result of the research it was established that variations (La/Yb)N in the IRS from the northern part of the Beaufort cycle are characterized by the values 8.5-15.5. They fully correspond to the average value of this parameter in the suspension of pp. Mackenzie and the Arctic-Red River (8.6 and 8.5) and the mean (La/Yb)N for the crystalline formations of the Canadian Shield (14.4). In the same range are included, the values of (La/Yb)N for the suspension of Yana and Lena rivers (8.7 and 12.4), which may indicate the possibility of the presence in the IRS of material borrowed on the shelf of the eastern Laptev Sea. In the Co-Cr diagram, there is no overlapping of the fields of the compositions of the present bottom sediments of the estuary of Yenisei River, on the one hand, and the eastern part of the East Siberian and Chukchi seas, on the other. Although the sediments of the delta of the Mackenzie River, comparable to the precipitation of the estuary of the Yenisei River. by the content of Cr and differ from them by a noticeably lower content of Co. In the Cr-La diagram, the IRS field occupies an essentially isolated position, yet still has a certain overlap with the precipitation fields of the Chukchi Sea and the delta of Mackenzie River. In the diagram (La/Yb)N-La/Co, the field of IRS composition has a ≈50% overlap with the field of the present bottom sediments composition of the Chukchi Sea. The middle point of the suspension also gravitates towards Lena River, and the point of the Canadian Shield is relatively close, as well as the points of suspension of Mackenzie and Arctic-Red rivers and PAAS. Overlapping of the IRS fields and modern bottom sediments of the Ob and Yenisei estuaries, as well as the east of the East Siberian Sea, on the contrary, is not observed. The data given in the article allow us to conclude that the IRS in the area of the North Pole contains sedimentary material, borrowed both on the shelf of the Beaufort Sea and on the shelves of the eastern part of the Laptev Sea and the Chukchi Sea

    Genome-wide association study reveals genetic variants associated with HIV-1C infection in a Botswana study population

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    Although there have been many studies of gene variant association with different stages of HIV/AIDS progression in United States and European cohorts, few gene-association studies have assessed genic determinants in sub-Saharan African populations, which have the highest density of HIV infections worldwide. We carried out genome-wide association studies on 766 study participants at risk for HIV-1 subtype C (HIV-1C) infection in Botswana. Three gene associations (AP3B1, PTPRA, and NEO1) were shown to have significant association with HIV-1C acquisition. Each gene association was replicated within Botswana or in the United States–African American or United States–European American AIDS cohorts or in both. Each associated gene has a prior reported influence on HIV/AIDS pathogenesis. Thirteen previously discovered AIDS restriction genes were further replicated in the Botswana cohorts, extending our confidence in these prior AIDS restriction gene reports. This work presents an early step toward the identification of genetic variants associated with and affecting HIV acquisition or AIDS progression in the understudied HIV-1C afflicted Botswana population

    Genome-wide sequence analyses of ethnic populations across Russia

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    The Russian Federation is the largest and one of the most ethnically diverse countries in the world, however no centralized reference database of genetic variation exists to date. Such data are crucial for medical genetics and essential for studying population history. The Genome Russia Project aims at filling this gap by performing whole genome sequencing and analysis of peoples of the Russian Federation. Here we report the characterization of genome-wide variation of 264 healthy adults, including 60 newly sequenced samples. People of Russia carry known and novel genetic variants of adaptive, clinical and functional consequence that in many cases show allele frequency divergence from neighboring populations. Population genetics analyses revealed six phylogeographic partitions among indigenous ethnicities corresponding to their geographic locales. This study presents a characterization of population-specific genomic variation in Russia with results important for medical genetics and for understanding the dynamic population history of the world's largest country

    Enhanced Lifetime Of Excitons In Nonepitaxial Au/cds Core/shell Nanocrystals

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    The ability of metal nanoparticles to capture light through plasmon excitations offers an opportunity for enhancing the optical absorption of plasmon-coupled semiconductor materials via energy transfer. This process, however, requires that the semiconductor component is electrically insulated to prevent a backward charge flow into metal and interfacial states, which causes a premature dissociation of excitons. Here we demonstrate that such an energy exchange can be achieved on the nanoscale by using nonepitaxial Au/CdS core/shell nanocomposites. These materials are fabricated via a multistep cation exchange reaction, which decouples metal and semiconductor phases leading to fewer interfacial defects. Ultrafast transient absorption measurements confirm that the lifetime of excitons in the CdS shell (tau approximate to 300 ps) is much longer than lifetimes of excitons in conventional, reduction-grown Au/CdS heteronanostructures. As a result, the energy of metal nanoparticles can be efficiently utilized by the semiconductor component without undergoing significant nonradiative energy losses, an important property for catalytic or photovoltaic applications. The reduced rate of exciton dissociation in the CdS domain of Au/CdS nanocomposites was attributed to the nonepitaxial nature of Au/CdS interfaces associated with low defect density and a high potential barrier of the interstitial phase

    FGF4 Independent Derivation of Trophoblast Stem Cells from the Common Vole

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    The derivation of stable multipotent trophoblast stem (TS) cell lines from preimplantation, and early postimplantation mouse embryos has been reported previously. FGF4, and its receptor FGFR2, have been identified as embryonic signaling factors responsible for the maintenance of the undifferentiated state of multipotent TS cells. Here we report the derivation of stable TS-like cell lines from the vole M. rossiaemeridionalis, in the absence of FGF4 and heparin. Vole TS-like cells are similar to murine TS cells with respect to their morphology, transcription factor gene expression and differentiation in vitro into derivatives of the trophectoderm lineage, and with respect to their ability to invade and erode host tissues, forming haemorrhagic tumours after subcutaneous injection into nude mice. Moreover, vole TS-like cells carry an inactive paternal X chromosome, indicating that they have undergone imprinted X inactivation, which is characteristic of the trophoblast lineage. Our results indicate that an alternative signaling pathway may be responsible for the establishment and stable proliferation of vole TS-like cells

    Energy Resolution Performance of the CMS Electromagnetic Calorimeter

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    The energy resolution performance of the CMS lead tungstate crystal electromagnetic calorimeter is presented. Measurements were made with an electron beam using a fully equipped supermodule of the calorimeter barrel. Results are given both for electrons incident on the centre of crystals and for electrons distributed uniformly over the calorimeter surface. The electron energy is reconstructed in matrices of 3 times 3 or 5 times 5 crystals centred on the crystal containing the maximum energy. Corrections for variations in the shower containment are applied in the case of uniform incidence. The resolution measured is consistent with the design goals
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