Моделирование напряженно-деформированного состояния участка зубочелюстного аппарата человека с учетом контактного взаимодействия между зубами и их частичного отсутствия

Complex interaction of incisors of the multi-element system “jaw – tooth – periodontium – enamel – dentinˮ is considered in the present work. The model was created on the basis of tomographic images taking into account previous studies of the human dental apparatus for a simplified model of three molars. The aim of the work is to determine the stress-strain states of the “jaw – periodontium – tooth – dentinˮ system for a different number of incisors and their location using three-dimensional computer finite-element modeling. The results of the study allow obtaining a more complete and accurate assessment of the state of the human dentofacial apparatus as a whole and each of its elements separately in order to improve the technologies and methods of prosthetics.В представленной работе рассмотрено комплексное взаимодействие резцов многоэлементной системы «челюсть – зуб – периодонт – эмаль – дентин». Модель создана на основе томографических снимков с учетом предыдущих исследований зубочелюстного аппарата человека на упрощенной модели для трех моляров. Целью работы является определение с помощью трехмерного компьютерного конечно-элементного моделирования напряженно-деформированных состояний системы «челюсть – периодонт – зуб – дентин» для различного количества резцов и их расположения. Результаты исследования позволяют получить более полную и точную оценку состояния зубочелюстного аппарата человека в целом и каждого его элемента в отдельности с целью совершенствования технологий и методов протезирования

Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month follow-up

Aim. To study the clinical course specifics of coronavirus disease 2019 (COVID-19) and comorbid conditions in COVID-19 survivors 3, 6, 12 months after recovery in the Eurasian region according to the AKTIV register. Material and methods.The AKTIV register was created at the initiative of the Eurasian Association of Therapists. The AKTIV register is divided into 2 parts: AKTIV 1 and AKTIV 2. The AKTIV 1 register currently includes 6300 patients, while in AKTIV 2 — 2770. Patients diagnosed with COVID-19 receiving in- and outpatient treatment have been anonymously included on the registry. The following 7 countries participated in the register: Russian Federation, Republic of Armenia, Republic of Belarus, Republic of Kazakhstan, Kyrgyz Republic, Republic of Moldova, Republic of Uzbekistan. This closed multicenter register with two nonoverlapping branches (in- and outpatient branch) provides 6 visits: 3 in-person visits during the acute period and 3 telephone calls after 3, 6, 12 months. Subject recruitment lasted from June 29, 2020 to October 29, 2020. Register will end on October 29, 2022. A total of 9 fragmentary analyzes of the registry data are planned. This fragment of the study presents the results of the post-hospitalization period in COVID-19 survivors after 3 and 6 months. Results. According to the AKTIV register, patients after COVID-19 are characterized by long-term persistent symptoms and frequent seeking for unscheduled medical care, including rehospitalizations. The most common causes of unplanned medical care are uncontrolled hypertension (HTN) and chronic coronary artery disease (CAD) and/or decompensated type 2 diabetes (T2D). During 3- and 6-month follow-up after hospitalization, 5,6% and 6,4% of patients were diagnosed with other diseases, which were more often presented by HTN, T2D, and CAD. The mortality rate of patients in the post-hospitalization period was 1,9% in the first 3 months and 0,2% for 4-6 months. The highest mortality rate was observed in the first 3 months in the group of patients with class II-IV heart failure, as well as in patients with cardiovascular diseases and cancer. In the pattern of death causes in the post-hospitalization period, following cardiovascular causes prevailed (31,8%): acute coronary syndrome, stroke, acute heart failure. Conclusion. According to the AKTIV register, the health status of patients after COVID-19 in a serious challenge for healthcare system, which requires planning adequate health system capacity to provide care to patients with COVID-19 in both acute and post-hospitalization period

Development of algorithm for transmission of electrocardiogram and its parameters

One of important problems in modern medicine is monitoring of parameters of an electrocardiogram. This can help to detect cardiovascular diseases. If patient has a cardiovascular disease, then it is important to monitor his state outside a hospital. In this paper we describe the developed algorithm of transmission of electrocardiogram and its parameters. The algorithm takes into account the properties of wireless technologies of transmission and can be used in portable devices intended for electrocardiogram registration and monitoring

Cardiac arrhythmia analysis used in the system of electrocardiosignal transmission to the supervision center

In the paper, we consider an algorithm for analyzing a person's heart condition. This algorithm is intended for systems of wireless electrocardiosignal transfer to the supervision and analysis center. Such systems are very useful when it is necessary to promptly estimate condition and operation work of the heart. Thus, more thorough analysis can be carried out later.These systems can be successfully used in medicine of accidents (ministry of emergency rescue) while evaluating condition of vehicle drivers, of sportsmen during training, of people at home.It is especially important to detect various kinds of cardiac arrhythmias at early stages. In our work, we have developed the block diagram of algorithm detecting the basic kinds of cardiac arrhythmias using logical formulae

THE STATEMENT OF THE PROBLEM OF MODELING THE DEPENDENCE OF THE FINENESS OF THE CATHODE TITANIUM POWDER AND CURRENT EFFICIENCY ON CURRENT DENSITY

Постановка задачи моделирования зависимости крупности катодного порошка титана и выхода по току от плотности тока процесса его получения из солевого расплава

Population genetic structure and phylogeography of sterlet (Acipenser ruthenus, Acipenseridae) in the Ob and Yenisei river basins

The sterlet (Acipenser ruthenus Linnaeus, 1758) is a relatively small sturgeon widely distributed in Eurasian rivers from the Danube to the Yenisei. During the twentieth century, all wild sterlet populations have declined due to anthropogenic factors including: overfishing, poaching, construction of dams, and pollution. Despite the necessity of characterization both wild and captive stocks, few studies of population genetics have been performed thus far. Here we studied the genetic diversity and geographic structure of sterlet populations across the eastern range – Ob-Irtysh and Yenisei basins – by sequencing a 628-bp fragment of mitochondrial DNA control region. We identified 98 new haplotypes, delineated 12 haplogroups and estimated the time of basal haplogroup divergence within the species as over 8 million years ago. Our data suggest that Ob-Irtysh and Yenisei populations are isolated from each other and much lower genetic diversity is present in the Yenisei population than in the Ob-Irtysh population. Our data imply that sterlet populations in Siberian rivers underwent bottleneck or fragmentation, followed by subsequent population expansion. The data obtained here are important for sterlet population monitoring and restocking management