An assessment of PenSim2

The Department for Work and Pensions (DWP)’s Pensim2 model is a dynamic microsimulation model. The principal purpose of this model is to estimate the future distribution of pensioner incomes, thus enabling analysis of the distributional effects of proposed changes to pension policy. This paper presents the results of an assessment of Pensim2 by researchers at the IFS. We start by looking at the overall structure of the model, and how it compares with other dynamic policy analysis models across the world. We make recommendations at this stage as to how the overall modelling strategy could be improved. We then go on to analyse the characteristics of most of the individual modules which make up Pensim2, examining the data used and the regression and predictions used in each step. The results from this examination are used to formulate a set of short and medium-term recommendations for developing and improving the model. Finally, we look at what might become possible for the model over a much longer time frame – looking towards developing a ‘Pensim3’ model over the next decade or so

William H. Shephard Interview

Transcript of oral history interview with William H. Shepard on his experiences during the Vietnam War on July 26, 1983

Complete Weight Enumerators of Generalized Doubly-Even Self-Dual Codes

For any q which is a power of 2 we describe a finite subgroup of the group of invertible complex q by q matrices under which the complete weight enumerators of generalized doubly-even self-dual codes over the field with q elements are invariant. An explicit description of the invariant ring and some applications to extremality of such codes are obtained in the case q=4

P19-53 LB. Priming with recombinant BCG expressing HIV-1 Gag or RT and boosting with recombinant MVA induces an effective immune response in mice

Mycobacterium bovis BCG (BCG) has a number of characteristics that give it great potential to act as a vehicle for the delivery of recombinant vaccines. However, its success depends on overcoming the challenges of poor antigen expression levels and genetic instability. Our studies using an optimized mycobacterial shuttle vector which utilizes the Mycobacterium tuberculosis mtrA promoter, induced upon infection of macrophages, and the M. tuberculosis 19 kDa signal sequence may overcome these issues. We have used this system to generate a recombinant BCG (rBCG) expressing HIV-1 subtype C full length Gag or reverse transcriptase (RT)

A Measure of Retroactive Inhibition in Motor Learning

In everyday life it is a common experience to find that some established response interferes with the learning of some new response. Thus the automobile driver finds it somewhat difficult to learn to shift gears using a control on the steering column after having shifted them by means of an older type control. The typist finds that she has trouble learning to type on a second keyboard in which the keys are located in relatively different positions. These are examples of a phenomenon known as proactive inhibition. This term is generally used to refer to a decrement in performance or rate of learning of one task resulting from the prior learning of some other task

Elliptic curve configurations on Fano surfaces

The elliptic curves on a surface of general type constitute an obstruction for the cotangent sheaf to be ample. In this paper, we give the classification of the configurations of the elliptic curves on the Fano surface of a smooth cubic threefold. That means that we give the number of such curves, their intersections and a plane model. This classification is linked to the classification of the automorphism groups of theses surfaces.Comment: 17 pages, accepted and shortened version, the rest will appear in "Fano surfaces with 12 or 30 elliptic curves

Carbon bridged biphenolate ligands in rare earth chemistry

Rare earth biphenolate species have become an increasingly studied series of complexes, owing to the diversity they offer over mononuclear aryloxide complexes, as well as their efficacy as catalysts and initiators in a range of organic transformations and polymerisation reactions. Compared to monodentate aryloxide ligands, biphenolate ligand systems are still in their infancy in rare earth coordination chemistry. In their limited use, the ligand 2,2 '-methylenebis(6-tert-butyl-4-methylphenol) (mbmpH(2)) has been a popular candidate. This review aims to highlight the chemistry that has been explored thus far with these carbon bridged lanthanoid biphenolate systems

Anxiety and attentional bias to threat in children at increased familial risk for Autism Spectrum Disorder

Anxiety and threat bias were examined in 6-8-year-old children at familial-risk for Autism Spectrum Disorder (ASD) and low-risk (LR, n = 37) controls. The high-risk (HR) group was divided into those who met diagnostic criteria for ASD (HR-ASD, n = 15) and those who did not (HR-non ASD, n = 24). The HR-ASD group had highest levels of parent-reported anxiety. The HR-non ASD group exhibited increased threat bias on a spatial-cueing task, while the HR-ASD group did not. Anxiety symptoms were associated with both threat bias and ASD severity. These findings suggest that the mechanisms underlying anxiety in HR siblings without ASD are similar to those in non-ASD populations. However, among children with ASD, hypersensitivity to threat may not underlie anxiety symptoms

Quantum affine Cartan matrices, Poincare series of binary polyhedral groups, and reflection representations

We first review some invariant theoretic results about the finite subgroups of SU(2) in a quick algebraic way by using the McKay correspondence and quantum affine Cartan matrices. By the way it turns out that some parameters (a,b,h;p,q,r) that one usually associates with such a group and hence with a simply-laced Coxeter-Dynkin diagram have a meaningful definition for the non-simply-laced diagrams, too, and as a byproduct we extend Saito's formula for the determinant of the Cartan matrix to all cases. Returning to invariant theory we show that for each irreducible representation i of a binary tetrahedral, octahedral, or icosahedral group one can find a homomorphism into a finite complex reflection group whose defining reflection representation restricts to i.Comment: 19 page