Scalar BSDEs of iterated-logarithmically sublinear generators with integrable terminal values

We establish a general existence and uniqueness of integrable adapted solutions to scalar backward stochastic differential equations with integrable parameters, where the generator $g$ has an iterated-logarithmic uniform continuity in the second unknown variable $z$. The result improves our previous one in \cite{FanHuTang2023SCL}.Comment: 15 page

Random Green's function method for large-scale electronic structure calculation

We report a linear-scaling random Green's function (rGF) method for large-scale electronic structure calculation. In this method, the rGF is defined on a set of random states to stochastically express the density matrix, and rGF is calculated with the linear-scaling computational cost. We show the rGF method is generally applicable to the nonorthogonal localized basis, and circumvent the large Chebyshev expansion for the density matrix. As a demonstration, we implement rGF with density-functional Tight-Binding method and apply it to self-consistently calculate water clusters up 9984 H2Os. We find the rGF method combining with a simple fragment correction can reach an error of ~1meV per H2O in total energy, compared to the deterministic calculations, due to the self-average. The development of rGF method advances the stochastic electronic structure theory to a new stage of the efficiency and applicability.Comment: 5 pages, 2 figure

Reference Pulse Attack on Continuous-Variable Quantum Key Distribution with Local Local Oscillator under trusted phase noise

We show that partially trusting the phase noise associated with estimation uncertainty in a LLO CVQKD system allows one to exchange higher secure key rates than in the case of untrusted phase noise. However, this opens a security loophole through the manipulation of the reference pulse amplitude. We label this as "reference pulse attack" which is applicable to all LLO-CVQKD systems if the phase noise is trusted. We show that, at the optimal reference pulse intensity level, Eve achieves unity attack efficiency at 23.8km and 32.0km while using lossless and 0.14dB/km loss channels, respectively, for her attack. However, in order to maintain the performance enhancement from partially trusting the phase noise, countermeasures have been proposed. As a result, the LLO-CVQKD system with partially trusted phase noise owns a superior key rate at 20km by an order 9.5, and extended transmission distance by 45%, than that of the phase noise untrusted system

Reference Pulse Attack on Continuous-Variable Quantum Key Distribution with Local Local Oscillator

We reveal a security loophole in the current state-of-art phase reference pulse sharing scheme for Continuous Variable Quantum Key Distribution using a Local Local Oscillator (LLO-CVQKD). The loophole is associated with the amplitude of the phase reference pulses which Eve can manipulate to extract information which cannot be discovered by legitimate users. We call this new attack as the reference pulse attack. We have demonstrated the efficiency of our attack for different LLO-CVQKD transmission distances. Unity attack efficiency can be achieved at a transmission distance greater than 21.2 km in the case of a zero loss channel. The distance extends to 24.3 km where hollow-core fibre channels are used. We also propose possible countermeasures

Th17/Treg Cells Imbalance and GITRL Profile in Patients with Hashimoto’s Thyroiditis

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Correlation between the frequency of Th17 cell and the expression of microrna-206 in patients with dermatomyositis

It was reported that IL-17 had been detected in the inflammatory infiltrates of patients with DM (dermatomyositis). In this study, we investigated the frequency of Th17 cells and the expression of microRNA-206 (miR-206) in DM patients. Firstly, we observed that the frequency of Th17 cells and the expression of transcription factors were increased significantly in the PBMCs of DM patients. Secondly, we found that there was a positive correlation between the percentages of Th17 cells and serum level of CK in DM patients. And the serum concentrations of IL-6, IL-1 , TGF-, and IL-23, the important cytokines of Th17 differentiation, were increased in DM patients. It was predicted that Krüppel-like factor 4 (KLF4) is one of the multiple targets of miR-206. We detected the expression of miR-206 in DM patients, and it was decreased in the serum and PBMCs of DM patients. The augmented expression of KLF is accompanied by the attenuated expression of miR-206. Furthermore, a negative correlation between the percentages of Th17 cells and the expression of miR-206 in DM patients has been found. Taken together, these findings suggest the attenuated expression of miR-206, and the augmented frequency of Th17 cells in DM patients

Ectopic tissue engineered ligament with silk collagen scaffold for ACL regeneration: A preliminary study

Anterior cruciate ligament (ACL) reconstruction remains a formidable clinical challenge because of the lack of vascularization and adequate cell numbers in the joint cavity. In this study, we developed a novel strategy to mimic the early stage of repair in vivo, which recapitulated extra-articular inflammatory response to facilitate the early ingrowth of blood vessels and cells. A vascularized ectopic tissue engineered ligament (ETEL) with silk collagen scaffold was developed and then transferred to reconstruct the ACL in rabbits without interruption of perfusion. At 2 weeks after ACL reconstruction, more well-perfused cells and vessels were found in the regenerated ACL with ETEL, which decreased dramatically at the 4 and 12 week time points with collagen deposition and maturation. ACL treated with ETEL exhibited more mature ligament structure and enhanced ligament-bone healing post-reconstructive surgery at 4 and 12 weeks, as compared with the control group. In addition, the ETEL group was demonstrated to have higher modulus and stiffness than the control group significantly at 12 weeks post-reconstructive surgery. In conclusion, our results demonstrated that the ETEL can provide sufficient vascularity and cellularity during the early stages of healing, and subsequently promote ACL regeneration and ligament-bone healing, suggesting its clinic use as a promising therapeutic modality. Statement of Significance Early inflammatory cell infiltration, tissue and vessels ingrowth were significantly higher in the extra articular implanted scaffolds than theses in the joint cavity. By mimicking the early stages of wound repair, which provided extra-articular inflammatory stimulation to facilitate the early ingrowth of blood vessels and cells, a vascularized ectopic tissue engineered ligament (ETEL) with silk collagen scaffold was constructed by subcutaneous implantation for 2 weeks. The fully vascularized TE ligament was then transferred to rebuild ACL without blood perfusion interruption, and was demonstrated to exhibit improved ACL regeneration, bone tunnel healing and mechanical properties. (C) 2017 Published by Elsevier Ltd on behalf of Acta Materialia Inc

Multi-dimensional backward stochastic differential equations of diagonally quadratic generators: The general result

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