Are COVID-19 models blind to the social determinants of health? A systematic review protocol

Introduction Infectious disease models are important tools to inform public health policy decisions. These models are primarily based on an average population approach and often ignore the role of social determinants in predicting the course of a pandemic and the impact of policy interventions. Ignoring social determinants in models may cause or exacerbate inequalities. This limitation has not been previously explored in the context of the current pandemic, where COVID-19 has been found to disproportionately affect marginalised racial, ethnic and socioeconomic groups. Therefore, our primary goal is to identify the extent to which COVID-19 models incorporate the social determinants of health in predicting outcomes of the pandemic. Methods and analysis We will search MEDLINE, EMBASE, Cochrane Library and Web of Science databases from December 2019 to August 2020. We will assess all infectious disease modelling studies for inclusion of social factors that meet the following criteria: (a) focused on human spread of SARS-CoV-2; (b) modelling studies; (c) interventional or non-interventional studies; and (d) focused on one of the following outcomes: COVID-19-related outcomes (eg, cases, deaths), non-COVID-19-related outcomes (ie, impacts of the pandemic or control policies on other health conditions or health services), or impact of the pandemic or control policies on economic outcomes. Data will only be extracted from models incorporating social factors. We will report the percentage of models that considered social factors, indicate which social factors were considered, and describe how social factors were incorporated into the conceptualisation and implementation of the infectious disease models. The extracted data will also be used to create a narrative synthesis of the results. Ethics and dissemination Ethics approval is not required as only secondary data will be collected. The results of this systematic review will be disseminated through peer-reviewed publication and conference proceedings. PROSPERO registration number CRD42020207706

Optimizing measurement of subjective amplitude of accommodation with defocus curves

PURPOSE: To determine whether letter sequences and/or lens-presentation order should be randomized when measuring defocus curves and to assess the most appropriate criterion for calculating the subjective amplitude of accommodation (AoA) from defocus curves. SETTING: Eye Clinic, School of Life & Health Sciences, Aston University, Birmingham, United Kingdom. METHODS: Defocus curves (from +3.00 diopters [D] to -3.00 D in 0.50 D steps) for 6 possible combinations of randomized or nonrandomized letter sequences and/or lens-presentation order were measured in a random order in 20 presbyopic subjects. Subjective AoA was calculated from the defocus curves by curve fitting using various published criteria, and each was correlated to subjective push-up AoA. Objective AoA was measured for comparison of blur tolerance and pupil size. RESULTS: Randomization of lens-presentation order and/or letter sequences, or lack of, did not affect the measured defocus curves (P>.05, analysis of variance). The range of defocus that maintains highest achievable visual acuity (allowing for variability of repeated measurement) was better correlated to (r = 0.84) and agreed best with ( 0.50 D) subjective push-up AoA than any other relative or absolute acuity criterion used in previous studies. CONCLUSIONS: Nonrandomized letters and lens presentation on their own did not affect subjective AoA measured by defocus curves, although their combination should be avoided. Quantification of subjective AoA from defocus curves should be standardized to the range of defocus that maintains the best achievable visual acuity

Comparison of near visual acuity and reading metrics in presbyopia correction

PURPOSE: To provide a consistent standard for the evaluation of different types of presbyopic correction. SETTING: Eye Clinic, School of Life and Health Sciences, Aston University, Birmingham, United Kingdom. METHODS: Presbyopic corrections examined were accommodating intraocular lenses (IOLs), simultaneous multifocal and monovision contact lenses, and varifocal spectacles. Binocular near visual acuity measured with different optotypes (uppercase letters, lowercase letters, and words) and reading metrics assessed with the Minnesota Near Reading chart (reading acuity, critical print size [CPS], CPS reading speed) were intercorrelated (Pearson product moment correlations) and assessed for concordance (intraclass correlation coefficients [ICC]) and agreement (Bland-Altman analysis) for indication of clinical usefulness. RESULTS: Nineteen accommodating IOL cases, 40 simultaneous contact lens cases, and 38 varifocal spectacle cases were evaluated. Other than CPS reading speed, all near visual acuity and reading metrics correlated well with each other (r>0.70, P<.001). Near visual acuity measured with uppercase letters was highly concordant (ICC, 0.78) and in close agreement with lowercase letters (+/- 0.17 logMAR). Near word acuity agreed well with reading acuity (+/- 0.16 logMAR), which in turn agreed well with near visual acuity measured with uppercase letters 0.16 logMAR). Concordance (ICC, 0.18 to 0.46) and agreement (+/- 0.24 to 0.30 logMAR) of CPS with the other near metrics was moderate. CONCLUSION: Measurement of near visual ability in presbyopia should be standardized to include assessment of near visual acuity with logMAR uppercase-letter optotypes, smallest logMAR print size that maintains maximum reading speed (CPS), and reading speed. J Cataract Refract Surg 2009; 35:1401-1409 (C) 2009 ASCRS and ESCR

Internet Use and Addiction Among Medical Students in Qassim University, Saudi Arabia

ABSTRACT: Objectives: This study aimed to measure the prevalence of Internet use and addiction and determine its association with gender, academic performance and health among medical students. Methods: This cross-sectional study was conducted between December 2017 and April 2018 at the College of Medicine, Qassim University, Buraydah, Saudi Arabia. The validated Internet Addiction Test questionnaire was distributed by simple random methods to medical students (N = 216) in the pre-clinical phase (first-, second- and third-years). A chi-square test was used to determine significant relationships between Internet use and addiction and gender, academic performance and health. Results: A total of 209 student completed the questionnaire (response rate: 96.8%) and the majority (57.9%) were male. In total, 12.4% were addicted to the Internet and 57.9 had the potential to become addicted. Females were more frequent Internet users than males (P = 0.006). Academic performance was affected in 63.1% of students and 71.8% lost sleep due to late-night Internet use, which affected their attendance to morning activities. The majority (59.7%) expressed feeling depressed, moody or nervous when they were offline. Conclusion: Internet addiction among medical students at Qassim University was very high, with addiction affecting academic performance and psychological well-being. Suitable interventional and preventive measures are needed for proper Internet use to protect students’ mental and physical health.Keywords: Internet; Addictive Behavior; Medical Students; Universities; Academic Performance; Saudi Arabia

Rotational and centration stability of an aspheric intraocular lens with a simulated toric design

Purpose: To assess the stability of the Akreos AO intraocular lens (IOL) platform with a simulated toric design using objective image analysis. Setting: Six hospital eye clinics across Europe. Methods: After implantation in 1 eye of patients, IOLs with orientation marks were imaged at 1 to 2 days, 7 to 14 days, 30 to 60 days, and 120 to 180 days. The axis of rotation and IOL centration were objectively assessed using validated image analysis. Results: The study enrolled 107 patients with a mean age of 69.9 years ± 7.7 (SD). The image quality was sufficient for IOL rotation analysis in 91% of eyes. The mean rotation between the first day postoperatively and 120 to 180 days was 1.93 ± 2.33 degrees, with 96% of IOLs rotating fewer than 5 degrees and 99% rotating fewer than 10 degrees. There was no significant rotation between visits and no clear bias in the direction of rotation. In 71% of eyes, the dilation and image quality was sufficient for image analysis of centration. The mean change in centration between 1 day and 120 to 180 days was 0.21 ± 0.11 mm, with all IOLs decentering less than 0.5 mm. There was no significant decentration between visits and no clear bias in the direction of the decentration. Conclusion: Objective analysis of digital retroillumination images taken at different postoperative periods shows the aspheric IOL platform was stable in the eye and is therefore suitable for the application of a toric surface to correct corneal astigmatism

NASA Mars Weather Station

The purpose of this project is to design an economical ground based weather station, with the overall goal of using these stations to gather meteorological data on the planet Mars. This data will then be used to create a working meteorological model for the planet, which in turn will be used to better coordinate the necessary resources to plan and carry out a manned mission to Mars. These weather stations will function by taking various meteorological measurements, such as air and ground temperature, wind speed, relative humidity, UV radiation levels, and air pressure, and then transmit this data to one of the Mars orbiters, which will then send the data to Earth. These measurements are to be taken every 100 seconds, day and night, for at least one full Martian year (two Earth years). The major concern with this proposal was making sure that the design itself remains as economical as possible, but at the same time remaining durable enough to survive in the Martian environment, as well as having the longevity to remain functional for more than one Martian year. In order to tackle this problem, the development of the stations was broken down into four separate areas of focus, being data collection, data transmission, power supply, and transportation, with additional considerations towards cost, durability, and feasibility. Taking into account these areas of focus and considerations, a product was designed that would function by using pre-existing technologies that could be easily replicated.https://scholarscompass.vcu.edu/capstone/1219/thumbnail.jp

Numerical Study for MHD Stagnation-Point Flow of a Micropolar Nanofluid Towards a Stretching Sheet

In this paper, we investigated the magnetohydrodynamic (MHD) stagnation-point flow of micropolar nanofluid over a stretching sheet. A uniform magnetic field is applied normal to the flow. Nonlinear micropolar nanofluid problem in the presence of the strong concentration of microelements is modeled and then solved by numerical techniques. A parametric study of the involved parameters in the presence of spin gradient viscosity is conducted, and representative set of numerical results is illustrated in the graphical and tabular forms. The complete formulation of the Keller-box method for the considered flow problem is given, and a comparison of the obtained results is performed with the previous published results. The comparison shows that our present results have an excellent match with the previous results in a limiting case. We found that the non-dimensional temperature and its associated thermal boundary layer thickness are enhanced when we use the larger values of thermophoresis and Brownian motion parameter. The non-dimensional concentration is higher for larger thermophoresis parameter but smaller for higher Brownian motion parameter. It is also observed that the smaller values of Lewis number correspond to higher non-dimensional concentration and its associated boundary layer thickness

First occurrence of the ant genus Brachymyrmex Mayr, 1868 (Hymenoptera: Formicidae) from the Kingdom of Saudi Arabia

The formicine ant genus Brachymyrmex Mayr, 1868 is recorded for the first time from the Kingdom of Saudi Arabia and from the Arabian Peninsula by the species B. cordemoyi Forel, 1895. A brief description and automontage images of the species are presented with ecological and biological notes

Assessment of dysphotopsia in pseudophakic subjects with multifocal intraocular lenses

Aim: To better understand the phenomenon of dysphotopsia in patients implanted with multifocal intraocular lenses (IOLs). Methods: Forty-five patients (aged 61.8±8.9 years) implanted bilaterally with Tecnis ZM900 (diffractive multifocal), Lentis Mplus MF30 (segmented refractive multifocal) or Softec-1 (monofocal) IOLs (each n=15) 4–6 months previously and who had achieved a good surgical outcome were examined. Each reported their dysphotopsia symptoms subjectively, identified its form (EyeVisPod illustrations), quantified retinal straylight (C-Quant) and halo perception (Aston halometer). Retinal straylight and halometry was repeated by a second masked clinician to determine interobserver repeatability. Results: Subjective dysphotopsia ratings were able to differentiate Tecnis ZM900 from Lentis Mplus MF30 (p0.10) quantification or between straylight and the halo area (p>0.30). Conclusions: Multifocal IOLs induce symptoms of dysphotopsia. Straylight did not differentiate between IOL designs, however halometry identified clear differences in light scatter due to the IOL optics. Whereas, subjective rating of overall dysphotopsia are not strongly associated with straylight or halo perception, the halometry polar diagram reflected the subjective descriptions of dysphotopsia

DAWM: cost-aware asset claim analysis approach on big data analytic computation model for cloud data centre.

The heterogeneous resource-required application tasks increase the cloud service provider (CSP) energy cost and revenue by providing demand resources. Enhancing CSP profit and preserving energy cost is a challenging task. Most of the existing approaches consider task deadline violation rate rather than performance cost and server size ratio during profit estimation, which impacts CSP revenue and causes high service cost. To address this issue, we develop two algorithms for profit maximization and adequate service reliability. First, a belief propagation-influenced cost-aware asset scheduling approach is derived based on the data analytic weight measurement (DAWM) model for effective performance and server size optimization. Second, the multiobjective heuristic user service demand (MHUSD) approach is formulated based on the CPS profit estimation model and the user service demand (USD) model with dynamic acyclic graph (DAG) phenomena for adequate service reliability. The DAWM model classifies prominent servers to preserve the server resource usage and cost during an effective resource slicing process by considering each machine execution factor (remaining energy, energy and service cost, workload execution rate, service deadline violation rate, cloud server configuration (CSC), service requirement rate, and service level agreement violation (SLAV) penalty rate). The MHUSD algorithm measures the user demand service rate and cost based on the USD and CSP profit estimation models by considering service demand weight, tenant cost, and energy cost. The simulation results show that the proposed system has accomplished the average revenue gain of 35%, cost of 51%, and profit of 39% than the state-of-the-art approaches