Archives and Literary History: English House

This presentation is part of a Directed Study project and was given at Clark FEST 2022. It is also associated with the longer paper, The Malleability of Home: A Genealogy of Clark University\u27s English House, composed collaboratively by the authors. It is about the history of Clark\u27s English Department and, particularly, about the House it occupies. This presentation was presented orally by Christina Rose Walcott for a public audience as a culminating project in the Directed Study, and includes visual and interactive educational components. It also utilizes and showcases the project\u27s extensive use of Open Access Resources from various digital archives

The Malleability of Home: A Genealogy of Clark University\u27s English House

This essay details the history of the land and structures that occupy the property currently located at the corner of Hawthorne and Woodland Streets in Worcester, Mass. Covering over 300 years, it begins with the legacies of the Nipmuc and the early English colonialist settlers before moving into a discussion of Worcester\u27s 19th Century industrialists and 20th Century acquisition by the University. The essay builds on extensive archival research using materials from both physical and digital collections such as atlases, censuses, biographies, directories, criticism, and more. To further develop the story of the English Department and its home, the essay also relies on oral histories conducted by the authors with retired professors of the department

Positive veteran teachers: Who are they, and where are they to be found?

Teacher career trajectory studies have identified a small group of veteran teachers who remain positive and committed to teaching, while others become disenchanted or disengaged. These, and related studies suggest key characteristics of positive veteran teachers revolve around a strong sense of agency and professional identity including: 1) a continuing desire to experiment and embrace challenges; 2) high levels of personal comfort in their teaching roles; and 3) a willingness to take on leadership roles across a range of capacities and contexts, and in turn be affirmed in these roles. While studies describe these characteristics, there has been little attempt utilise them as the basis for constructs in the formal identification of these teachers, and in turn examine where these teachers are to be found in education systems. This article reports on a study in Australia which sought to utilise the characteristics to identify positive veteran teachers within a larger cohort, and examine demographic information surrounding them. Reported demographics include gender, location (city / country), age and school type (primary / secondary / K-12). The ability to identify these teachers and where they are to be found may help educational authorities understand and promote conditions in which more veteran teachers are able to sustain their passion and commitment to the job

‘Maybe I can do this. Maybe I should be here’: Evaluating an academic literacy, resilience and confidence programme

It has been well documented in research that students from so-called ‘non-traditional’ backgrounds can experience significant difficulty in accessing Higher Education, in part due to a lack of cultural capital. This is further reinforced by ‘invisible pedagogic practices’ (Tapp 2015), which uphold the prestige of disciplines such as ‘critical analysis’, ‘structure’ and ‘argument’ without adequately inducting students into such practices. Through the evaluation of an academic literacy intervention (‘ARC’) designed to improve the academic resilience and confidence of students on an undergraduate degree programme, this paper demonstrates that ‘literacy’ is as much a social practice as it is a set of applied skills. Thus, ‘academic literacy’ should constitute both study skills and academic socialisation. This paper further argues that the acquisition of ‘academic literacy’ necessitates the adoption of an ‘academic identity’; which is an emotional, as well as an intellectual endeavour. This requires institutions to move away from the deficit model of ‘academic literacy support’ towards models which enable the construction of a shared academic identity and cultivate a sense of belonging to the university environment

A Combined Therapeutic Regimen of Buspirone and Environmental Enrichment is more Efficacrious than Either Alone in Enhancing Spatial Learning in Brain-Injured Rats

Abstract Buspirone, a 5-HT1A receptor agonist, and environmental enrichment (EE) enhance cognition and reduce histopathology after traumatic brain injury (TBI) in adult rats, but have not been fully evaluated after pediatric TBI, which is the leading cause of death in children. Hence, the aims of this study were to assess the efficacy of buspirone alone (Experiment 1) and in combination with EE (Experiment 2) in TBI postnatal day-17 male rats. The hypothesis was that both therapies would confer cognitive and histological benefits when provided singly, but their combination would be more efficacious. Anesthetized rats received a cortical impact or sham injury and then were randomly assigned to receive intraperitoneal injections ofbuspirone (0.08 mg/kg, 0.1 mg/kg, and 0.3 mg/kg) or saline vehicle (1.0 mL/kg) 24 h after surgery and once daily for 16 days (Experiment 1). Spatial learning and memory were assessed using the Morris water maze (MWM) on post-operative days 11-16, and cortical lesion volume was quantified on day 17. Sham controls for each condition were significantly better than all TBI groups. In the TBI groups, buspirone (0.1 mg/kg) enhanced MWM performance versus vehicle and buspirone (0.08 mg/kg and 0.3 mg/kg) (p\u3c0.05) and reduced lesion volume relative to vehicle (p=0.038). In Experiment 2, buspirone (0.1 mg/kg) or vehicle was combined with EE after TBI, and the data were compared to the standard (STD)-housed groups from Experiment 1. EE lead to a significant enhancement of spatial learning and a reduction in lesion size versus STD. Moreover, the combined treatment group (buspirone+EE) performed markedly better than the buspirone+STD and vehicle+EE groups, which suggests an additive effect and supports the hypothesis. The data replicate previous studies assessing these therapies in adult rats. These novel findings may have important rehabilitation-relevant implications for clinical pediatric TBI

The impact of anaerobic digestate on soil life: a review

Using organic amendments to fertilise crops is a crucial part in the sustainability of agricultural systems. The residual slurry remaining after biogas production (anaerobic digestate) contains a rich source of plant nutrients that provides an alternative to mineral fertilisers. The delivery of many nutrients to plants is facilitated by a healthy soil biota: free-living and symbiotic microflora (e.g. archaea, bacteria and fungi) mineralize, solubilize and facilitate plant uptake of nutrients and the soil fauna (e.g. protozoa, microarthopods and earthworms) influence nutrient cycling processes as higher-level consumers and litter transformers. The delivery of nutrients to plants via the activity of this soil food web is influenced by fertiliser inputs. Here we review the impact of anaerobic digestate on soil biota. The quantity and composition of the carbon in digestate has a large influence on soil heterotrophic microbial dynamics and their subsequent influence on nutrient bioavailability. The main points are (1) digestate low in carbon has little effect on soil microorganisms, whereas digestate higher in carbon increases soil microbial abundance and diversity; (2) labile carbon stimulates fast-growing bacteria, whereas recalcitrant carbon shifts the microbial community in favour of slower-growing fungi and Gram-positive bacteria; and (3) earthworms, springtails and nematodes dwelling in the soil surface layer can be negatively affected by digestate application due to toxicity when compounds such as ammonia are present in high concentrations. Generalized understanding of the effect by digestates on soil biota is made difficult by differences in digestate properties caused by varying feedstock and production methods and the inherent heterogeneity of soil. There is a lack of research investigating the impact of repeated digestate application on soil biota and subsequently soil health. This information would give end users more confidence to substitute mineral fertilisers with digestate

No Fall Too Small: Assessing Barriers to Fall Prevention Programs

In Vermont, 1/3 of adults 45 years or older fell in the year 2018, statistically above the national average, which has not changed since 2012. Of those who fell, 34% experienced an injury after their fall. Evidence-based interventions and fall prevention programs effectively reduce falls, and these programs aimed at reducing falls appear to reduce fractures. In fact, it has been shown that exercise intervention reduces fall risk by 30%. Our review of the literature highlighted that there are numerous barriers to accessing fall prevention programs, including loss of independence, transportation, cost, and lack of interest. With this in mind, we investigated the potential barriers to accessing and attending fall prevention programs in Vermont.https://scholarworks.uvm.edu/comphp_gallery/1311/thumbnail.jp

Model-Based Prediction of the Patient-Specific Response to Adrenaline

A model for the cardiovascular and circulatory systems has previously been validated in simulated cardiac and circulatory disease states. It has also been shown to accurately capture the main hemodynamic trends in porcine models of pulmonary embolism and PEEP (positive end-expiratory pressure) titrations at different volemic levels. In this research, the existing model and parameter identification process are used to study the effect of different adrenaline doses in healthy and critically ill patient populations, and to develop a means of predicting the hemodynamic response to adrenaline. The hemodynamic effects on arterial blood pressures and stroke volume (cardiac index) are simulated in the model and adrenaline-specific parameters are identified. The dose dependent changes in these parameters are then related to adrenaline dose using data from studies published in the literature. These relationships are then used to predict the future, patient-specific response to a change in dose or over time periods from 1-12 hours. The results are compared to data from 3 published adrenaline dosing studies comprising a total of 37 data sets. Absolute percentage errors for the identified model are within 10% when re-simulated and compared to clinical data for all cases. All identified parameter trends match clinically expected changes. Absolute percentage errors for the predicted hemodynamic responses (N=15) are also within 10% when re-simulated and compared to clinical data. Clinically accurate prediction of the effect of inotropic circulatory support drugs, such as adrenaline, offers significant potential for this type of model-based application. Overall, this work represents a further clinical, proof of concept, of the underlying fundamental mathematical model, methods and approach, as well as providing a template for using the model in clinical titration of adrenaline in a decision support role in critical care. They are thus a further justification in support of upcoming human clinical trials to validate this model

Oxygen supply capacity breathes new life into critical oxygen partial pressure (Pcrit)

Author Posting. © Company of Biologists, 2021. This article is posted here by permission of Company of Biologists for personal use, not for redistribution. The definitive version was published in Journal of Experimental Biology 224(8), (2021): jeb242210, https://doi.org/10.1242/jeb.242210.The critical oxygen partial pressure (Pcrit), typically defined as the PO2 below which an animal's metabolic rate (MR) is unsustainable, is widely interpreted as a measure of hypoxia tolerance. Here, Pcrit is defined as the PO2 at which physiological oxygen supply (α0) reaches its maximum capacity (α; µmol O2 g−1 h−1 kPa−1). α is a species- and temperature-specific constant describing the oxygen dependency of the maximum metabolic rate (MMR=PO2×α) or, equivalently, the MR dependence of Pcrit (Pcrit=MR/α). We describe the α-method, in which the MR is monitored as oxygen declines and, for each measurement period, is divided by the corresponding PO2 to provide the concurrent oxygen supply (α0=MR/PO2). The highest α0 value (or, more conservatively, the mean of the three highest values) is designated as α. The same value of α is reached at Pcrit for any MR regardless of previous or subsequent metabolic activity. The MR need not be constant (regulated), standardized or exhibit a clear breakpoint at Pcrit for accurate determination of α. The α-method has several advantages over Pcrit determination and non-linear analyses, including: (1) less ambiguity and greater accuracy, (2) fewer constraints in respirometry methodology and analysis, and (3) greater predictive power and ecological and physiological insight. Across the species evaluated here, α values are correlated with MR, but not Pcrit. Rather than an index of hypoxia tolerance, Pcrit is a reflection of α, which evolves to support maximum energy demands and aerobic scope at the prevailing temperature and oxygen level.This project was supported by National Oceanic and Atmospheric Administration grants NA18NOS4780167 and NA17OAR4310081 and National Science Foundation grant OCE-1459243 to B.A.S., the Jack and Katharine Ann Lake Fellowship to A.A., the Anne and Werner Von Rosenstiel Fellowship and Garrels Memorial Endowed Fellowship to A.W.T., the Hogarth Fellowship to C.J.W., the Southern Kingfish Association Fellowship to A.L.B., and a National Science Foundation postdoctoral fellowship (DBI-1907197) to M.A.B.2022-04-3