Воспроизведение связности при переводе юридического документа

Адекватне відтворення когерентності посідає важливе місце при перекладі сучасного юридичного дискурсу. У статті робиться спроба з’ясувати типи й види зв’язності юридичного документа та особливості їх відтворення при перекладі, визначити завдання перекладача задля забезпечення адекватного сприйняття перекладу читачами цільової мови.Rendering of the source text coherence is highly significant when translating modern legal document. The article attempts at establishing the types and varieties of the coherence of the legal document, as well as at defining translator’s goals for preservation of correct perception of the translation by target language readers.При переводе современных юридических документов важное место отводится передаче их когерентности. В статье предпринято попытку установить типы и виды связности юридического документа, особенности их воспроизведения при переводе, определить задачи переводчика с целью обеспечения адекватного восприятия перевода

Predictors of personality orientation on free (entrepreneurial) activity

In this paper, the theoretical aspects of entrepreneurial orientation and conducted diagnostics of personal qualities and an entrepreneurial career orientationВ данной работе рассмотрены теоретические аспекты предпринимательской ориентации и проведена диагностика личностных качеств и предпринимательской карьерной ориентаци

A clinical case of choroidal effusion associated with the use of carbonic anhydrase inhibitors

Relevance. Choroidal effusion is a complication accompanying both surgical interventions and ophthalmopathies of predominantly inflammatory etiology. The release of proteins from choriocapillaries lumen and decrease of intraocular pressure relative to the pressure in the episcleral veins lead to the chor oid detachment.Purpose. To analyze the causal link between choroidal effusion and topical application of carbonic anhydrase inhibitors using a clinical example.Material and methods. The paper describes a clinical case of the development of unilateral recurrent choroidal effusion 13 years after sinus trabeculectomy associated with the use of carbonic anhydrase inhibitors. The first episode of choroidal effusion was induced by a fixed combination of brinzolamide with timolol, while the use of dorzolamide caused the repeated episode. The clinical picture was accompanied by significant decrease in visual acuity related to acute hypotension and severe folds of the descemet’s membrane. Ultrasonic B-scanning revealed the choroid detachment. The dechallenge of carbonic anhydrase inhibitors, the use of anti-inflammatory and cycloplegic drugs contributed to achieve the choroid adherence.Results. This clinical case clearly demonstrates a causal link between choroidal effusion and topical application of carbonic anhydrase inhibitors. The timely drug therapy made it possible to avoid surgical intervention. Intraocular pressure increased later. Brimonidine was prescribed to reduce it, the intraocular pressure was normalized, and the clinical picture stabilized.Conclusion. Ciliochoroidal effusion may occur in the eyes with primary angle-closure glaucoma even several years after surgical treatment in the setting of the use of this group of hypotensive drugs. It is necessary to take a balanced approach to the use of carbonic anhydrase inhibitors in each particular case, i ncluding in primary angle-closure glaucoma

Synthesis, polarity, and structure of 2-chloro-N-[2-(methylsulfanyl)phenyl]- and 2-(diphenylthiophosphoryl)-N-[2-(methylsulfanyl)phenyl]acetamides

© 2015 Pleiades Publishing, Ltd. Conformations of 2-chloro-N-[2-(methylsulfanyl)phenyl]- and 2-(diphenylthiophosphoryl)-N-[2-(methylsulfanyl)phenyl]acetamides have been studied by the dipole moment method and quantum chemical calculations. 2-(Diphenylthiophosphoryl)-N-[2-(methylsulfanyl)phenyl]acetamide has been found to exist as an equilibrium mixture of two conformers with synclinal and anticlinal orientations of the {C-{s{p^3}}} - {C-{s{p^2}}} and P=S bonds. 2-Chloro-N-[2-(methylsulfanyl)phenyl]acetamide is represented by one preferred conformer

The Key Features and Periodization of Socialist Realism in the Literary Context

The article deals with the research on various aspects of socialist realism from the perspective of belles-lettres. It analyzes the essence and key features of this phenomenon, makes a generalization of approaches to the periodization of socialist realism. In the research, we used historical-typological and sociological methods for the analysis of historical documents and criticism in order to clarify the party policy in the field of literature. The psychoanalytic method was used to study the means of the writer adaptation to the Soviet dictatorship. Anthropological and intertextual methods were used to clarify the peculiarities of the national culture and the literary codes of socialist realism. The method of reconstruction allowed us to depict the picture of the past with the help of archival documents, epistolary, memoirs, etc. It is found out that the formation of socialist realism resulted from the mixture of culture and state party dictatorship in literature and art. Socialist realism provided political manipulation of the mass consciousness and performed the regulatory function for social communication. It is proved that the theory of socialist realism was based on such categories as ideiinist (ideology), klasovist (class content), and partiinist (party-mindedness). At the same time, such categories as creative imagination, fantasy, and fiction were denied. When creating literary texts, writers used ready-made templates, clichés, and stereotypes affecting our perception. The authors of the article analyzed the influence of socialist realism on the cultural preferences of that time’s citizens. The article graphically accumulates the main approaches to the periodization of socialist realism. We analyze the research of H. Gunter, Yu. Boriev, V. Klymchuk, V. Tiupa, and characterize each period. It is revealed that the literature of socialist realism was interpreted on the behavioral (attitude to the state policy) and creative (themes, style, images) levels. In the article, the authors characterize the key features of socialist realism in the context of the structural-stylistic, worldview-universal, figurative (characterological) directions

Conformational analysis of 2-aminophenyl-, 2-aminobenzyl-, and 2-nitrobenzyl(diphenyl)phosphine oxides

The polarity and conformations of 2-aminophenyl-, 2-aminobenzyl-, and 2-nitrobenzyl(diphenyl)-phosphine oxides were studied by the dipole moment method, IR spectroscopy, and quantum chemical calculations. 2-Aminophenyl- and 2-aminobenzyl(diphenyl)phosphine oxides were found to exist preferentially as conformers with intramolecular hydrogen bond. 2-Nitrobenzyl(diphenyl)phosphine oxide is likely to be represented by equilibrium mixture of three conformers in which the phosphoryl and nitro groups are oriented syn or anti with respect to the PCsp3 Csp2 fragment. © 2014 Pleiades Publishing, Ltd

Antibiofilm activity of aminopropanol derivatives against Pseudomonas aeruginosa

Bacterial biofilm, particularly formed by Pseudomonas aeruginosa, are a cause of severe chronic infectious diseases. Bacteria within a biofilm are phenotypically more resistant to antibiotics and the macroorganism immune system, making it an important virulence factor for many microbes. The aminopropanol derivatives with adamantyl (KVM-97) and N-alkylaryl radicals (KVM-194, KVM-204, KVM-261, and KVM-262) were used as study object. The aim of this study was to investigate the antibiofilm activity of compounds on biofilm formation and on mature biofilm of P. aeruginosa. The effects of the aminopropanol derivatives on the biofilm mass were evaluated by using crystal violet assay. Ciprofloxacin, meropenem, ceftazidime, gentamicin were used as reference substances. Reported results demonstrate that all compounds displayed antibiofilm activity at the tested concentrations. Remarkable reduction in biofilm formation of P. aeruginosa was found after treatment with KVM-97, KVM-261 and KVM-262 in high concentration (5× MIC), biofilm inhibition activity were 84.3%, 90.5% and 83.3% respectively. After a treatment with KVM-204 at 250 μg/ml (5× MIC) 76.6% of the preformed 24-hr biofilms were destroyed. Furthermore, compounds KVM-97, KVM-194, and KVM-261 in both concentrations showed potent antibiofilm activity against the P. aeruginosa, inhibition activity values being between 56.7 and 65.7%. All tested compounds in dose-dependent manner exhibited pronounced inhibition activity against mature 5-days P. аeruginosa biofilm. It was also observed that tested compounds show high antibiofilm activity in comparison to reference antimicrobials. The aminopropanol derivatives may provide templates for a new group of antimicrobial agents and potential future therapeutics for treating chronic infections

Antiseptic properties of aminoadamantane derivative

Development of microbial resistance to current antimicrobial drugs created a critical need of the new antiseptics. The object of our study was phenyladamantane derivative (4-(adamantyl-1)-1-(1-aminobutyl)benzol, AM-166). The aim of the presented study was to investigate the specific activity of 4% AM-166 solution in isopropanol and 5% AM-166 solution in 76% ethanol (manufactured by PJSC SIC «Borshchahivskiy CPP») against the wide spectrum of bacteria and fungi, and effective concentrations and exposition time determination. Desinfectant/antiseptic activity was evaluated by quantitative suspension method with subsequent neutralization. Our results showed that both solutions exhibited similar activity against gram-positive and gram-negative bacteria as well as against yeasts. Antibacterial and antifungal action was demonstrated for all investigated concentrations (initial solution, 5-fold and 10-fold dilutions), observed effect was maintained throughout the whole observation period (from 5 to 30 min). Tested solutions in initial concentrations demonstrated fungicidal activity against A. niger. 5-fold dilution of 5% AM-166 solution in 76% ethanol was more effective than 5-fold dilution of 4% AM-166 solution in isopropanol. 10-fold dilutions of both solutions were ineffective against A. niger. The data obtained suggest the prospects of adamantane derivatives for the development of novel antiseptics

Development and experience of using the educational online course for students of medical specialties

Students' interest in distance education, which is currently available on-line, was shown using questionnaires. An electronic textbook on pharmacognosy and herbal medicine has been created for students and specialists in the pharmaceutical, medical and biological fields.Интерес студентов к дистанционному обучению, доступному в настоящее время online, было показано с помощью анкетирования. Создано электронное учебное пособие по фармакогнозии и фитотерапии для студентов и специалистов фармацевтического, медицинского и биологического профиля