Methods of physical impact on natural gas in order to improve the safety of its transportation through main pipelines

The article considers the technology absorption natural gas dehydration, systematization of the physical processes occurring in the technological chain of preparation of natural gas. Built fuzzy causal model of the process gas drying based on the combined application of fuzzy inference and neural network approximation. The use of the model enables the structural and parametric optimization of production, aimed at improving the quality of preparation of natural gas

Solving optimization problems of optimal control of operational parameters of oil reservoir

The paper proposes a method for solving optimal control operating parameters of oil stratum: the arrangement of injection and production wells; regulation works well in setting of the two-phase filtration. Depending on the optimization of the planning horizon on the basis of the proposed method gives the prediction of increasing production by 27 % in the long-term planning up to 60 % for short-term planning

Building and optimizing a model of low level for two-phase filtration

The paper proposes a method for constructing models of low level for two-phase flow based on a combination of finite-difference solutions and detailed spatial approximation, providing the possibility of approximating the models for solving optimal control the operating parameters of the oil reservoir

Optimization of research and methodology work at university in terms of the process approach

© by the authors. The objective of this article is to improve the research and methodology work at university providing regulatory and instructional work of university teachers. The submitted article presents a way of managing a scientific -methodological work in terms of process approach that ensures quality of educational activities at university. The basis of the submitted work are the ideas of total quality management including the cycle of continuous activity improvement. The authors have developed the principles and process algorithm "Management of research and methodology work at university," diagnostic tools of evaluating university teachers' activity. This article is intended for educators, researchers, heads of educational institutions involved in design and management of research and methodology work in higher education

IR Bismuth active centers in optical fibers: Combined excitation-emission spectroscopy

3D excitation-emission luminescence spectra of Bi-doped optical fibers of various compositions were measured in a wide wavelength range 450-1700 nm. Such luminescence spectra were obtained for Bi-doped pure silica and germania fibers, and for Bi-doped Al- or P-codoped silica fibers (at room and liquid nitrogen temperatures). The energy level schemes of IR bismuth active centers in pure silica and germania core fibers were derived from spectra obtained. The energy level schemes similarity of bismuth active centers in these two types of fibers was revealed.Comment: 12pages, 7 figures, 5 table

Optimization of thermal design and geometrical parameters of a flat tube-fin adsorbent bed for automobile air-conditioning

Adsorbent bed design and performance strongly affect the overall performance of adsorption systems. In the present study, an analytical model was developed to determine the optimum geometrical and thermal parameters of a flat tube-fin adsorbent bed to reach the maximum system performance. This types of heat exchangers offer substantial reduced in weight, cost, volume and thermal conductivity, which can make them a good choice for adsorbent beds in automobile applications. Results showed that the overall thermal conductance of the bed and the maximum practical specific cooling capacity increased when reducing in flat tube thickness and fin pitch as well as by increasing in fin thickness and water channel wall thickness. The specific thermal conductance increased by 2.5% when reducing the channel pitch from its design value to a minimum permissible (0.004 m). From thermal parameters that have been studied, the adsorbent thermal conductivity is the most sensitive parameter to the specific thermal conductance in beds. The system performance also significantly enhanced by reducing the mass of the metal bed and the heat transfer fluids as well as the desorption heat of the selecting working pair. (C) 2016 Elsevier Ltd. All rights reserved.This work has been partially supported by the Thermally Operated Mobile Air Conditioning Systems (TOPMACS).Verde Trindade, M.; Harby Mohamed Abd Alaal, K.; Corberán, JM. (2017). Optimization of thermal design and geometrical parameters of a flat tube-fin adsorbent bed for automobile air-conditioning. Applied Thermal Engineering. 111:489-502. https://doi.org/10.1016/j.applthermaleng.2016.09.099S48950211

Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy

We introduce UnaG as a green-to-dark photoswitching fluorescent protein capable of high-quality super-resolution imaging with photon numbers equivalent to the brightest photoswitchable red protein. UnaG only fluoresces upon binding of a fluorogenic metabolite, bilirubin, enabling UV-free reversible photoswitching with easily controllable kinetics and low background under Epi illumination. The on- and off-switching rates are controlled by the concentration of the ligand and the excitation light intensity, respectively, where the dissolved oxygen also promotes the off-switching. The photo-oxidation reaction mechanism of bilirubin in UnaG suggests that the lack of ligand-protein covalent bond allows the oxidized ligand to detach from the protein, emptying the binding cavity for rebinding to a fresh ligand molecule. We demonstrate super-resolution single-molecule localization imaging of various subcellular structures genetically encoded with UnaG, which enables facile labeling and simultaneous multicolor imaging of live cells. UnaG has the promise of becoming a default protein for high-performance super-resolution imaging. Photoconvertible proteins occupy two color channels thereby limiting multicolour localisation microscopy applications. Here the authors present UnaG, a new green-to-dark photoswitching fluorescent protein for super-resolution imaging, whose activation is based on a noncovalent binding with bilirubin

INFLUENCE OF PRODUCTION METHODS OF THE INGOT AND TECHNOLOGIES OF ITS PROCESSING IN A SEMI-FINISHED PRODUCT ON THE STRUCTURE AND PROPERTIES OF ALLOYS BASED ON TITANIUM NICKELIDE

The influence of the quality of the charge material, the smelting method, the deformation modes, and the heat treatment of semi.finished products on the structure and characteristics of the SME of titanium nickelide binary alloys was investigated.В работе было исследовано влияние качества шихтового материала, метода выплавки, режимов деформации и термической обработки полуфабрикатов на структуру и характеристики ЭПФ двойных сплавов на основе никелида титана

Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors

Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination. In present study we employed 5′RACE UMI-based full length and nearly error-free immunoglobulin profiling to compare plasma cell antibody repertoires in young (19–26 years) and middle-age (45–58 years) individuals vaccinated with a live yellow fever vaccine, modeling a newly encountered pathogen. Our analysis has revealed age-related differences in the responding antibody repertoire ranging from distinct IGH CDR3 repertoire properties to differences in somatic hypermutation intensity and efficiency and antibody lineage tree structure. Overall, our findings suggest that younger individuals respond with a more diverse antibody repertoire and employ a more efficient somatic hypermutation process than elder individuals in response to a newly encountered pathogen