Effect of housing environment and laying hen strain on performance, egg quality and bone properties as well as cloacal and eggshell microbiology

Laying hen welfare is gaining importance in the United States and several states have passed legislation for a welfareriendly housing environment, which has forced the egg industry to explore alternative housing environments. For this reason, our first objective was to determine the effect of housing environment and laying hen strain on production performance and egg quality. Results showed that production performance of the hens raised in the alternative housing system was similar to the conventional system. The second objective was to compare the eggshell and cloacal microbiology. Our results indicated that the microbial load observed was higher in the alternative system compared to the conventional system. The third objective was to determine the effects of housing environment and laying hen strain on tibia and femur bone properties. The results demonstrated that the alternative system provided better tibia and femur bone characteristics, but it varied among laying hen strains

Impacts of \u3ci\u3eYartsa Gunbu\u3c/i\u3e Harvesting on Alpine Ecosystems in the Barun Valley, Makalu-Barun National Park, Nepal

Around 2003, the highly valuable medicinal fungi Ophiocordyceps sinensis (Nepali: yartsa gunbu) began to be commercially harvested in the remote Barun valley of the Makalu-Barun National Park and Buffer Zone, eastern Nepal. Since then, an estimated 3,000 collectors per year have visited the valley each harvesting season, placing new pressures upon its subalpine and alpine landscapes. A review of the yartsa gunbu literature suggested that its harvesting throughout highland India, Nepal, Bhutan, and China has brought important economic benefits, but that it has often been accompanied by a corresponding increase in negative environmental impacts such as alpine shrub destruction, wildlife poaching, and improper garbage disposal. Adverse social impacts reported have included an increase in violence, occasional murder, and the erosion of traditional values. In an attempt to determine if similar phenomena were occurring within the Barun valley, east Nepal, we conducted a month-long study of yartsa gunbu harvesting practices between May and June of 2016. Unlike other regions of the Himalaya, we found that violence and social unrest due to harvesting competition were unheard of in the Barun, which we link to the (a) lower market value of yartsa gunbu harvested there when compared to other regions, and (b) the recognized role of yartsa gunbu as a supplemental and livelihood diversifying income generation opportunity instead of a sole source of new income. Since its collection and sale were legalized by the Government of Nepal in 2001, the concurrent development of locally responsive yartsa gunbu harvesting policies and practices can also be linked to the general absence of environmental disturbance that we found

To obtain information about prescribing pattern of antibiotics: a prospective hospital based observational study

Objective: To obtain information about prescribing pattern of antibiotics in the tertiary care teaching hospital. Methods: The present prospective hospital based observational study was conducted among patients admitted to inpatient department of General Surgery, Sri Krishna Medical College and Hospital, Muzaffarpur, India from April 2019 to October 2019. Patients above 18 years of either sex were included in the study. Results: A total of 138 prescriptions were studied. Mean age of the study population was 38.16 years. Mean number of medicines prescribed per prescription was 4.69 and mean number of antibiotics per prescription was 2.18. Conclusion: Cephalosporin was the preferred or most prescribed choice of drug for prophylaxis followed by penicillin’s. Our study brings to the fore some common but serious lapses in antibiotic prescription patterns and emphasizes the need for proper and appropriate use of antibiotics

Impacts of Yartsa Gunbu Harvesting on Alpine Ecosystems in the Barun Valley, Makalu-Barun National Park, Nepal

Around 2003, the highly valuable medicinal fungi Ophiocordyceps sinensis (Nepali: yartsa gunbu) began to be commercially harvested in the remote Barun valley of the Makalu-Barun National Park and Buffer Zone, eastern Nepal. Since then, an estimated 3,000 collectors per year have visited the valley each harvesting season, placing new pressures upon its subalpine and alpine landscapes. A review of the yartsa gunbu literature suggested that its harvesting throughout highland India, Nepal, Bhutan, and China has brought important economic benefits, but that it has often been accompanied by a corresponding increase in negative environmental impacts such as alpine shrub destruction, wildlife poaching, and improper garbage disposal. Adverse social impacts reported have included an increase in violence, occasional murder, and the erosion of traditional values. In an attempt to determine if similar phenomena were occurring within the Barun valley, east Nepal, we conducted a month-long study of yartsa gunbu harvesting practices between May and June of 2016. Unlike other regions of the Himalaya, we found that violence and social unrest due to harvesting competition were unheard of in the Barun, which we link to the (a) lower market value of yartsa gunbu harvested there when compared to other regions, and (b) the recognized role of yartsa gunbu as a supplemental and livelihood diversifying income generation opportunity instead of a sole source of new income. Since its collection and sale were legalized by the Government of Nepal in 2001, the concurrent development of locally responsive yartsa gunbu harvesting policies and practices can also be linked to the general absence of environmental disturbance that we found

Multi-Atom Quasiparticle Scattering Interference for Superconductor Energy-Gap Symmetry Determination

Complete theoretical understanding of the most complex superconductors requires a detailed knowledge of the symmetry of the superconducting energy-gap $\Delta_\mathbf{k}^\alpha$, for all momenta $\mathbf{k}$ on the Fermi surface of every band $\alpha$. While there are a variety of techniques for determining $|\Delta_\mathbf{k}^\alpha|$, no general method existed to measure the signed values of $\Delta_\mathbf{k}^\alpha$. Recently, however, a new technique based on phase-resolved visualization of superconducting quasiparticle interference (QPI) patterns centered on a single non-magnetic impurity atom, was introduced. In principle, energy-resolved and phase-resolved Fourier analysis of these images identifies wavevectors connecting all k-space regions where $\Delta_\mathbf{k}^\alpha$ has the same or opposite sign. But use of a single isolated impurity atom, from whose precise location the spatial phase of the scattering interference pattern must be measured is technically difficult. Here we introduce a generalization of this approach for use with multiple impurity atoms, and demonstrate its validity by comparing the $\Delta_\mathbf{k}^\alpha$ it generates to the $\Delta_\mathbf{k}^\alpha$ determined from single-atom scattering in FeSe where $s_{\pm}$ energy-gap symmetry is established. Finally, to exemplify utility, we use the multi-atom technique on LiFeAs and find scattering interference between the hole-like and electron-like pockets as predicted for $\Delta_\mathbf{k}^\alpha$ of opposite sign

Assessing Spatio-Temporal Relationships of Criminal Activity and Temperature in Chicago

A research project supervised Milan Budhathoki in collaboration with a faculty from Big10 School. We have been exploring 20 years of daily temperature and crime in the City of Chicago to understand spatio-temporal pattern using GIS and data science method. We will presenting preliminary analysis from the project

WITHDRAWN: Clinical Neurorestorative Therapeutic Guidelines for Spinal Cord Injury (IANR/CANR Version 2019)

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Density dependent composition of InAs quantum dots extracted from grazing incidence x-ray diffraction measurements.

Epitaxial InAs quantum dots grown on GaAs substrate are being used in several applications ranging from quantum communications to solar cells. The growth mechanism of these dots also helps us to explore fundamental aspects of self-organized processes. Here we show that composition and strain profile of the quantum dots can be tuned by controlling in-plane density of the dots over the substrate with the help of substrate-temperature profile. The compositional profile extracted from grazing incidence x-ray measurements show substantial amount of inter-diffusion of Ga and In within the QD as a function of height in the low-density region giving rise to higher variation of lattice parameters. The QDs grown with high in-plane density show much less spread in lattice parameter giving almost flat density of In over the entire height of an average QD and much narrower photoluminescence (PL) line. The results have been verified with three different amounts of In deposition giving systematic variation of the In composition as a function of average quantum dot height and average energy of PL emission.The authors would like to acknowledge the support of Department of Science and Technology (DST) for carrying out synchrotron experiments at Petra III, DESY, Germany through the DST-DESY project and the EPSRC, UK for financial support.This is the final version of the article. It first appeared from NPG via http://dx.doi.org/10.1038/srep1573

Ovarian cancer G protein-coupled receptor 1 inhibits A549 cells migration through casein kinase 2α intronless gene and neutral endopeptidase

Background: We have previously reported that a new intronless gene for casein kinase 2α (CK2α), CSNK2A3, is expressed in human cells. The promoter of the well-known CK2α, CSNK2A1, displays characteristics of a housekeeping gene, whereas CSNK2A3 has a characteristic of a regulated promoter with two TATA boxes and a CAAT box. GPR68, a family of the G protein-coupled receptors, is also known as ovarian cancer G protein-coupled receptor 1 (OGR1). In the current study, we analyzed the roles of CK2α genes and neutral endopeptidase (NEP), a key enzyme that influences a variety of malignancies, in the OGR1-induced inhibition of A549 cell migration. Methods: We analyzed the transcript expressions of both the CK2α genes (CSNK2A1 and CSNK2A3) and NEP upon OGR1 overexpression. Protein expression of CK2α and NEP were also analyzed. We further elucidated the functional roles of both CK2α and NEP in the OGR1-induced inhibition of A549 cell migration in vitro using a wound-healing assay. We also analyzed the molecular mechanisms involved in the OGR1-induced inhibition of lung cancer cell migration. Results: The findings of this study showed that OGR1 upregulated the expression of CSNK2A3 but not CSNK2A1 in the A549 cells. The findings further suggested OGR1 also upregulates the expression of NEP. The OGR1-induced inhibition of A549 cell migration was abrogated completely by inhibition of CK2α activity, whereas partial abrogation (~ 30%) was observed in the presence of NEP inhibition. The results also revealed that OGR1 regulates CSNK2A3 via activation of Rac1/cdc42 and MAPKs pathways. CK2 is ubiquitously expressed, and in contrast, is believed to be a constitutively active enzyme, and its regulation appears to be independent of known second messengers. Conclusion: In the current study, we report for the first time the OGR1-induced regulation of CSNK2A3, CK2αP, and NEP in A549 cancer cells. Our study also decoded the downstream cellular proteins of OGR1 as well as the molecular mechanism involved in OGR1-induced inhibition of A549 cell migration. The findings of this research suggest the potential therapeutic targets to inhibit lung cancer progression