Quantitative and Qualitative Research on the Fear of Recurrence and the Belief in Prevention of Recurrence in Elderly Patients with Coronary Heart Disease

Objective: To explore the fear of recurrence and the belief in prevention of recurrence in elderly patients with coronary heart disease. Methods: A total of 178 elderly patients with coronary heart disease were included, and quantitative and qualitative research methods were used to explore the fear of recurrence and the belief in prevention of recurrence in elderly patients with coronary heart disease. The quantitative research tool was a self-made fear of coronary heart disease recurrence questionnaire; the qualitative research was guided by the phenomenological method, semi-structured in-depth interviews with 11 elderly patients with coronary heart disease, and the data were collected by recording, and the Colaizzi method was used to analyze the data. Results Elderly patients with coronary heart disease were afraid of recurrence; they knew the etiology of coronary heart disease, but the controllable rate of the cause and effect was extremely low. Conclusion: Due to the belief in fatalism and the lack of control over the etiology of coronary heart disease, elderly patients with coronary heart disease are afraid of recurrence

The effects of feeding ration and cheliped autotomy on the growth and expression of ecdysteroid receptor in early juvenile mud crabs, Scylla paramamosain

This study investigated the combined effects of feeding ration and cheliped autotomy on the intermolt duration, molting success, molt increments in size and weight, and ecdysteroid receptor gene (SpEcR) expression of early juvenile mud crab Scylla paramamosain. Newly molted second stage juvenile crabs (C2) were subjected to four feeding conditions; optimal, suboptimal (1/2 optimal), low (1/4 optimal) ration and starvation, and autotomy (intact vs. cheliped autotomy) in a 4 x 2 factorial design until all crabs successfully molted or died. A significant interaction of feeding ration and cheliped autotomy on intermolt duration was identified. With reduced feeding ration, both intact and cheliped autotomized crabs showed increased time and desynchrony of molting, but decreased carapace size and body weight. Importantly, all crabs with different feeding rations even the low ration had high rates of molting success (> 95%), while the crabs subjected to starvation died without molting. When fed optimal ration, the mean intermolt duration of the cheliped autotomized crabs was significantly prolonged, while no such effect was found between autotomized and intact crabs subjected to suboptimal or low feeding ration. The qRT-PCR revealed that the expression of SpEcR showed a general trend of inhibited by reduced feeding ration, which was consistent with observed significantly increased intermolt duration. Interestingly, the transcript level of SpEcR was only significantly affected by cheliped autotomy under the optimal and suboptimal feeding rations but not for the low feeding ration. Together, the results of this study suggest that the S. paramamosain early juveniles have a strong tolerance for fluctuations in food availability. In addition, the availability of food and limb autotomy could significantly affect growth, molting duration and synchrony of the crabs, which appeared to reflect in SpEcR expression level that involved in the regulation of molting and limb regeneration process of the juvenile crabs

Effects and Mechanism of Two Nanoparticles (Titanium Dioxide and Silver) to Moina mongolica Daday (Crustacea, Cladocera)

The nearshore and estuary are the main gathering areas of nanoparticles (NPs), and salinity change is a crucial characteristic in these marine areas. Moina mongolica Daday is an important open-ended bait in the nearshore aquaculture environment. Investigating the toxicity mechanism of NPs to M. mongolica under different salinity conditions is crucial to exploring the biological impact of NPs in the nearshore environment. Two typical metal oxide and metal NPs of TiO2 and Ag were used in this study to test the acute, chronic, and reproductive toxicities of M. mongolica (Cladocera) in marine environments of different salinity gradients. The toxic effects and mechanisms of the two NPs on M. mongolica were discussed by ecotoxicology and transcriptional analysis, respectively. A total of 27,274 genes were assembled, and 11,056 genes were successfully compared. Results suggested that TiO2 and Ag NPs showed particle toxicity with oxidation generation and immune emergencies on M. mongolica. Compared with TiO2, Ag NPs showed strong toxicity with reproductive toxicity due to the release of Ag+, resulting in a reduction in reproduction, which is a decrease in the number of offspring and the rm. Critical DEGs involved in carapace showed carapace damage of M. mongolica, due to adhesion and accumulation (approximately 40%–60% of all accumulation) on carapace, which was one of the toxic mechanisms of the two NPs. The salinity factor caused the aggregation of both NPs, and Ag+ release of Ag NPs. The toxicity of TiO2 NPs to M. mongolica increases with salinity, but that of Ag NPs decreases

Enumeration of Balanced Symmetric Functions over GF(p)

It is proved that the construction and enumeration of the number of balanced symmetric functions over GF(p) are equivalent to solving an equation system and enumerating the solutions. Furthermore, we give an lower bound on number of balanced symmetric functions over GF(p), and the lower bound provides best known results

New Constructions of Low Correlation Sequences with High Linear Complexity

In this paper, we propose a new concept named similar-bent function and we present two general methods to construct balanced sequences with low correlation by using similar-bent functions and orthogonal similar-bent functions. We nd that the bent sequence sets are special cases of our construction. We also investigate the linear complexity of the new constructed sequences. If a suitable similar-bent function is given, the sequences constructed by it can have high linear complexity. As examples, we construct two new low correlation sequence sets. One constructed based on Dobbertin\u27s iterative function is asymptotically optimal with respect to Welch\u27s bound and the other one is constructed based on Kasami function whose sequences have a high linear complexity

The retinoid X receptor from mud crab: new insights into its roles in ovarian development and related signaling pathway

In arthropods, retinoid X receptor (RXR) is a highly conserved nuclear hormone receptor. By forming a heterodimeric complex with the ecdysone receptor (EcR), RXR is known to be vital importance for various physiological processes. However, in comparison to EcR, the RXR signaling pathway and its roles in crustacean reproduction are poorly understood. In the present study, the RXR mRNA was detected in the ovarian follicular cells of mud crab Scylla paramamosain (SpRXR) and during ovarian maturation, its expression level was found to increase significantly. In vitro experiment showed hat both SpRXR and vitellogenin (SpVg) mRNA in the ovarian explants were significantly induced by 20-hydroxyecdysone (20E) but not methyl farnesoate (MF). However, differing from the in vitro experiment, injection of MF in in vivo experiment significantly stimulated the expressions of SpRXR and SpVg in female crabs at early vitellogenic stage, but the ecdysone and insect juvenile hormone (JH) signaling pathway genes were not induced. The results together suggest that both MF and SpRXR play significant roles in regulating the expression of SpVg and ovarian development of S. paramamosain through their own specific signaling pathway rather than sharing with the ecdysone or the insect JH

When a Boolean Function can be Expressed as the Sum of two Bent Functions

In this paper we study the problem that when a Boolean function can be represented as the sum of two bent functions. This problem was recently presented by N. Tokareva in studying the number of bent functions. Firstly, many functions, such as quadratic Boolean functions, Maiorana-MacFarland bent functions, partial spread functions etc, are proved to be able to be represented as the sum of two bent functions. Methods to construct such functions from low dimension ones are also introduced. N. Tokareva\u27s main hypothesis is proved for $n\leq 6$. Moreover, two hypotheses which are equivalent to N. Tokareva\u27s main hypothesis are presented. These hypotheses may lead to new ideas or methods to solve this problem. At last, necessary and sufficient conditions on the problem when the sum of several bent functions is again a bent function are given

Finding Small Solutions of the Equation Bx−Ay=zBx-Ay=z and Its Applications to Cryptanalysis of the RSA Cryptosystem

In this paper, we study the condition of finding small solutions $(x,y,z)=(x_0, y_0, z_0)$ of the equation $Bx-Ay=z$. The framework is derived from Wiener\u27s small private exponent attack on RSA and May-Ritzenhofen\u27s investigation about the implicit factorization problem, both of which can be generalized to solve the above equation. We show that these two methods, together with Coppersmith\u27s method, are equivalent for solving $Bx-Ay=z$ in the general case. Then based on Coppersmith\u27s method, we present two improvements for solving $Bx-Ay=z$ in some special cases. The first improvement pays attention to the case where either $\gcd(x_0,z_0,A)$ or $\gcd(y_0,z_0,B)$ is large enough. As the applications of this improvement, we propose some new cryptanalysis of RSA, such as new results about the generalized implicit factorization problem, attacks with known bits of the prime factor, and so on. The motivation of these applications comes from oracle based complexity of factorization problems. The second improvement assumes that the value of $C \equiv z_0\ (\mathrm{mod}\ x_0)$ is known. We present two attacks on RSA as its applications. One focuses on the case with known bits of the private exponent together with the prime factor, and the other considers the case with a small difference of the two prime factors. Our new attacks on RSA improve the previous corresponding results respectively, and the correctness of the approach is verified by experiments