384 research outputs found

    catena-Poly[(diaqua­strontium)-bis­{μ-5-[4-(1H-imidazol-1-yl)phen­yl]tetra­zolido}]

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    In the title complex polymer, [Sr(C10H7N6)2(H2O)2]n, the SrII atom lies on an inversion centre and is coordinated by four N atoms from two bidentate bridging trans-related 5-[4-(1H-imidazol-1-yl)phen­yl]tetra­zolide ligands [Sr—N = 2.387 (4) Å for the tetrazolide moiety and Sr—N = 2.273 (5) Å for the imidazole moiety], and by two O atoms from water mol­ecules [Sr—O = 2.464 (4) Å], giving a distorted octa­hedral coordination. Pairs of ligand bridges link the complex units, forming chains which extend along [111] and are inter-associated through Owater—H⋯N hydrogen bonds, giving a two-dimensional network structure parallel to (001). Weak π–π stacking inter­actions between the benzene and imidazole rings are also present [minimum ring centroid separation = 3.691 (4) Å]

    Systematic identification and characterization of chicken (Gallus gallus) ncRNAs

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    Recent studies have demonstrated that non-coding RNAs (ncRNAs) play important roles during development and evolution. Chicken, the first genome-sequenced non-mammalian amniote, possesses unique features for developmental and evolutionary studies. However, apart from microRNAs, information on chicken ncRNAs has mainly been obtained from computational predictions without experimental validation. In the present study, we performed a systematic identification of intermediate size ncRNAs (50–500 nt) by ncRNA library construction and identified 125 chicken ncRNAs. Importantly, through the bioinformatics and expression analysis, we found the chicken ncRNAs has several novel features: (i) comparative genomic analysis against 18 sequenced vertebrate genomes revealed that the majority of the newly identified ncRNA candidates is not conserved and most are potentially bird/chicken specific, suggesting that ncRNAs play roles in lineage/species specification during evolution. (ii) The expression pattern analysis of intronic snoRNAs and their host genes suggested the coordinated expression between snoRNAs and their host genes. (iii) Several spatio-temporal specific expression patterns suggest involvement of ncRNAs in tissue development. Together, these findings provide new clues for future functional study of ncRNAs during development and evolution
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