12 research outputs found
RFID based Attendance Management System
Radio-frequency identification (RFID) is a technology that uses radio waves to transfer data from an electronic tag, called RFID tag or label, attached to an object, through a reader for the purpose of identifying and tracking the object. RFID technology is a matured technology that has been widely deployed by various organizations as a part of their automation systems. In this project, an RFID based system has been built in order to produce an attendance management system. An automated attendance management software will not only make the entire process simple, but will also provide a well-structured and analyzed report of the pattern of student attendance and time management, which can further help in allocating and using the human resources in an organization to the maximum possible benefit. This system consists of two main parts which include: the hardware and the software. The hardware consists of a motor unit and RFID reader. The RFID reader, which is a low-frequency reader (125 kHz), is connected to the host computer via a serial to USB converter cable. The Time-Attendance System GUI is developed using Visual Basic.Net. The Attendance Management System provides the functionalities of the overall system such as displaying live ID tags transactions, registering ID, deleting ID, recording attendance and other minor functions. This interface was installed in the host computer.DOI:http://dx.doi.org/10.11591/ijece.v3i6.396
The Use of Core Warming as a Treatment for Coronavirus Disease 2019 (COVID-19): an Initial Mathematical Model
Background: Increasing data suggest that elevated body temperature may be helpful in resolving a variety of diseases, including sepsis, acute respiratory distress syndrome (ARDS), and viral illnesses. SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), may be more temperature sensitive than other coronaviruses, particularly with respect to the binding affinity of its viral entry via the ACE2 receptor. A mechanical provision of elevated temperature focused in a body region of high viral activity in patients undergoing mechanical ventilation may offer a therapeutic option that avoids arrhythmias seen with some pharmaceutical treatments. We investigated the potential to actively provide core warming to the lungs of patients with a commercially available heat transfer device via mathematical modeling, and examine the influence of blood perfusion on temperature using this approach. Methods: Using the software Comsol Multiphysics, we modeled and simulated heat transfer in the body from an intraesophageal warming device, taking into account the airflow from patient ventilation. The simulation was focused on heat transfer and warming of the lungs and performed on a simplified geometry of an adult human body and airway from the pharynx to the lungs. Results: The simulations were run over a range of values for blood perfusion rate, which was a parameter expected to have high influence in overall heat transfer, since the heat capacity and density remain almost constant. The simulation results show a temperature distribution which agrees with the expected clinical experience, with the skin surface at a lower temperature than the rest of the body due to convective cooling in a typical hospital environment. The highest temperature in this case is the device warming water temperature, and that heat diffuses by conduction to the nearby tissues, including the air flowing in the airways. At the range of blood perfusion investigated, maximum lung temperature ranged from 37.6°C to 38.6°C. Conclusions: The provision of core warming via commercially available technology currently utilized in the intensive care unit, emergency department, and operating room can increase regional temperature of lung tissue and airway passages. This warming may offer an innovative approach to treating infectious diseases from viral illnesses such as COVID-19, while avoiding the arrhythmogenic complications of currently used pharmaceutical treatments.
The Use of Core Warming as a Treatment for Coronavirus Disease 2019 (COVID-19): an Initial Mathematical Model
Background: Increasing data suggest that elevated body temperature may be helpful in resolving a variety of diseases, including sepsis, acute respiratory distress syndrome (ARDS), and viral illnesses. SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), may be more temperature sensitive than other coronaviruses, particularly with respect to the binding affinity of its viral entry via the ACE2 receptor. A mechanical provision of elevated temperature focused in a body region of high viral activity in patients undergoing mechanical ventilation may offer a therapeutic option that avoids arrhythmias seen with some pharmaceutical treatments. We investigated the potential to actively provide core warming to the lungs of patients with a commercially available heat transfer device via mathematical modeling, and examine the influence of blood perfusion on temperature using this approach. Methods: Using the software Comsol Multiphysics, we modeled and simulated heat transfer in the body from an intraesophageal warming device, taking into account the airflow from patient ventilation. The simulation was focused on heat transfer and warming of the lungs and performed on a simplified geometry of an adult human body and airway from the pharynx to the lungs. Results: The simulations were run over a range of values for blood perfusion rate, which was a parameter expected to have high influence in overall heat transfer, since the heat capacity and density remain almost constant. The simulation results show a temperature distribution which agrees with the expected clinical experience, with the skin surface at a lower temperature than the rest of the body due to convective cooling in a typical hospital environment. The highest temperature in this case is the device warming water temperature, and that heat diffuses by conduction to the nearby tissues, including the air flowing in the airways. At the range of blood perfusion investigated, maximum lung temperature ranged from 37.6°C to 38.6°C. Conclusions: The provision of core warming via commercially available technology currently utilized in the intensive care unit, emergency department, and operating room can increase regional temperature of lung tissue and airway passages. This warming may offer an innovative approach to treating infectious diseases from viral illnesses such as COVID-19, while avoiding the arrhythmogenic complications of currently used pharmaceutical treatments.
Dual ankyrinG and subpial autoantibodies in a man with well-controlled HIV infection with steroid-responsive meningoencephalitis: A case report
Neuroinvasive infection is the most common cause of meningoencephalitis in people living with human immunodeficiency virus (HIV), but autoimmune etiologies have been reported. We present the case of a 51-year-old man living with HIV infection with steroid-responsive meningoencephalitis whose comprehensive pathogen testing was non-diagnostic. Subsequent tissue-based immunofluorescence with acute-phase cerebrospinal fluid revealed anti-neural antibodies localizing to the axon initial segment (AIS), the node of Ranvier (NoR), and the subpial space. Phage display immunoprecipitation sequencing identified ankyrinG (AnkG) as the leading candidate autoantigen. A synthetic blocking peptide encoding the PhIP-Seq-identified AnkG epitope neutralized CSF IgG binding to the AIS and NoR, thereby confirming a monoepitopic AnkG antibody response. However, subpial immunostaining persisted, indicating the presence of additional autoantibodies. Review of archival tissue-based staining identified candidate AnkG autoantibodies in a 60-year-old woman with metastatic ovarian cancer and seizures that were subsequently validated by cell-based assay. AnkG antibodies were not detected by tissue-based assay and/or PhIP-Seq in control CSF (N = 39), HIV CSF (N = 79), or other suspected and confirmed neuroinflammatory CSF cases (N = 1,236). Therefore, AnkG autoantibodies in CSF are rare but extend the catalog of AIS and NoR autoantibodies associated with neurological autoimmunity
Dental caries in primary and permanent teeth in children's worldwide, 1995 to 2019: a systematic review and meta-analysis
Background: Early childhood caries (ECC) is a type of dental caries in the teeth of infants and children that is represented as one of the most prevalent dental problems in this period. Various studies have reported different types of prevalence of dental caries in primary and permanent teeth in children worldwide. However, there has been no comprehensive study to summarize the results of these studies in general, so this study aimed to determine the prevalence of dental caries in primary and permanent teeth in children in different continents of the world during a systematic review and meta-analysis. Methods: In this review study, articles were extracted by searching in the national and international databases of SID, MagIran, IranMedex, IranDoc, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (ISI) between 1995 and December 2019. Random effects model was used for analysis and heterogeneity of studies was evaluated by using the I2 index. Data were analyzed by using the Comprehensive Meta-Analysis (Version 2) software. Findings: In this study, a total of 164 articles (81 articles on the prevalence of dental caries in primary teeth and 83 articles on the prevalence of dental caries in permanent teeth) were entered the meta-analysis. The prevalence of dental caries in primary teeth in children in the world with a sample size of 80,405 was 46.2% (95% CI: 41.6–50.8%), and the prevalence of dental caries in permanent teeth in children in the world with a sample size of 1,454,871 was 53.8% (95% CI: 50–57.5%). Regarding the heterogeneity on the basis of meta-regression analysis, there was a significant difference in the prevalence of dental caries in primary and permanent teeth in children in different continents of the world. With increasing the sample size and the year of study, dental caries in primary teeth increased and in permanent teeth decreased. Conclusion: The results of this study showed that the prevalence of primary and permanent dental caries in children in the world was found to be high. Therefore, appropriate strategies should be implemented to improve the aforementioned situation and to troubleshoot and monitor at all levels by providing feedback to hospitals
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Socioecological drivers of complex social structure in an avian cooperative breeder
Cooperatively breeding societies, in which one or more non-parental individuals (“alloparents”) care for young alongside the parents, show considerable variation in social structure. Traditionally, such societies have been thought to comprise small, kin-based family groups where offspring from previous broods delay dispersal and help raise closely-related offspring to gain indirect fitness benefits when independent breeding opportunities are unavailable or yield lower fitness outcomes. However, genetic evidence is increasingly revealing cooperatively breeding species whose social groups comprise unrelated individuals as co-breeders or alloparents or both (for e.g., 45% of all avian cooperative breeders). Such social groups exhibit complexity in social structure such as large group size, multiple breeders, and low and varied group kin structure.
To understand why such complex societies form and how are they maintained when the opportunity to gain indirect benefits via kin selection is low and variable, I investigated the direct and indirect benefits driving a key demographic process, dispersal, and the resulting variation in group social structure on the individual, group, and population levels in an obligate, avian cooperative breeder, the superb starling (Lamprotornis superbus). I used a combination of long-term, individual-level data spanning 15 years from nine groups monitored at the Mpala Research Centre in Kenya and fine-scale genetic and environmental data sampled across 22 social groups that included the long-term study population.
In Chapter 1, I show that (i) dispersal decisions in superb starling males are driven by temporal environmental variation experienced by their parents pre-laying, (ii) both dispersal and philopatry result in equivalent lifetime inclusive fitness outcomes, and (iii) oscillating selection due to high temporal variability in the environment likely maintains the two alternative dispersal tactics, resulting in the formation of mixed-kin groups. In Chapter 2, I show that (i) immigrants are vital to the stability of superb starling social groups in light of low and variable offspring recruitment in a harsh, unpredictable environment, (ii) plural breeding likely arises as a result of reproductive concessions provided by group members as joining incentives to recruit immigrants, and (iii) despite smaller groups providing more reproductive concessions, immigrants gain higher fitness in larger social groups and thus prefer to immigrate into larger groups which are found in higher-quality territories.
Finally, in Chapter 3, I find genetic signatures of directional dispersal from social groups in low- to high-quality territories across an environmental gradient which likely generates considerable within-population variation in group social structure. Overall, my dissertation underscores the importance of direct benefits derived from group augmentation in the formation and maintenance of cooperative social groups with a complex social structure in a harsh and unpredictable environment
Delayed diagnosis of Q fever endocarditis in a rheumatoid arthritis patient
Chronic Q fever caused by Coxiella burnetii is uncommon in the United States and is most often associated with infective endocarditis. We present a 52-year-old woman with a history of aortic valve replacement and rheumatoid arthritis treated with Etanercept with chronic Q fever manifesting as prosthetic valve infective endocarditis. Explanted valve tissue showed organisms confirmed to be C. burnetii by PCR (polymerase chain reaction) sequencing. She subsequently reported consumption of unpasteurized cow milk which was the likely source of C. burnetii. She continues to do well 6 months after valve replacement on oral doxycycline and hydroxychloroquine