104 research outputs found

    Políticas públicas terrritorializadas no Brasil e na América Latina: algumas perspectivas de evolução e de agenda para a pesquisa

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    A comunicação trata da evolução dos processos de territorialização de políticas públicas no setor rural no Brasil e de algumas perspectivas de pesquisa sobre esse tema. A territorialização das políticas considera as especificidades de cada território em oposição ao enfoque vertical que divide a ação pública em setores de atividade separados. Segundo Faure (2007) “em sua formulação mais simples, a territorialização corresponde a uma abordagem política pública que valoriza as características e os recursos de cada território.. o território, mais do que o aparelho de Estado, seria agora o local de definição e solução de problemas públicos. ..supõe um tratamento localizado de certas questões e o desenvolvimento de uma pluralidade de atores envolvidos na produção de um laço político e social”. Encontramos três principais elementos para justificar a territorialização das políticas públicas: i) O serviço ou o bem público não é distribuído de maneira uniformizada pela autoridade central (Thoenig e Duran,1996; Faure, 2004); ii) existe uma tentativa de aproximar a tomada de decisão dos problemas e dos usuários ou beneficiários das políticas (Massardier, 2008; Duran, 2011); O território não é definido administrativamente mais de acordo com uma dinâmica especificamente territorial (Faure e Négrier, 2007). A exposição estará dividida em três partes: a primeira, após essa introdução, lembra as principais experiências de territorialização do desenvolvimento no Brasil. A segunda apresenta os principais enfoques de analise da territorialização e ensinamentos da sua aplicação na América latina. A terceira parte examina as principais escolas teóricas ou conceituas que promoveram a analise pela territorialização das politicas. A conclusão aponta algumas perspectivas para a pesquisa sobre esse tema a partir dos primeiros resultados do projeto “Pobreza, territórios e políticas públicas”

    The Gap Between Supportive Care Needs and the Care Provided in Adult Cancer Patients

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    Sağlık hizmetlerinin önemli bir birleşeni kanserli hastaya bakımda karşılanmamış destekleyici bakım ihtiyaçlarının belirlenmesi ve yönetilmesidir. Hastaların hangi gereksinimlerinin karşılanmadığının ve karşılanmamış ihtiyaçların yaygınlığının bilinmesi, hasta bakımının planlanmasında, onkoloji hizmetindeki boşlukları tespit ederek yeniden yapılandırmada yol gösterici olacaktır. Bu derlemenin amacı, yetişkin kanser hastalarının kanser yolculuğunun farklı aşamalarında -yeni tanı konma ve aktif tedavi dönemi, tedavi sonrası sağkalım süreci- ve tümör gruplarında -meme, over, prostat, akciğer, beyin tümörü gibi- karşılanmamış destekleyici bakım gereksinimlerini ve yaygınlığını incelemektir. Böylece, uluslararası kanser politikası çerçevesinde önemli bir kavram olmaya devam eden hastaların karşılanmamış gereksinimleri konusunu ülkemiz literatürüne kazandırmak, onkolojide veya genel hastanede kanser hastalarıyla çalışan sağlık profesyonellerinin konuya dikkatini çekmek ve ekip çalışmasıyla sunulabilecek hasta-merkezli holistik bakımın önemini vurgulamak mümkün olabilir. The identification and management of unmet supportive care needs of cancer patients is an important component of health-care services. Assessment of the nature and prevalence of patient needs that are not met will be guiding in the planning of patient-care, and in the identification of gaps in oncology services towards a necessary restructuring. The purpose of this review article is to determine the nature and prevalence of unmet supportive care needs of adult cancer patients through different stages over the course of the disease, i.e. diagnosis and active treatment, post-treatment survival and in various tumour groups such as breast, ovarian, prostate, lung and brain tumours. This study aims to contribute to the Turkish literature in the area of unmet patient needs as an important current concept in the framework of international cancer policy, to draw the attention of health-care professionals who work in the field of oncology in general or specialised wards, and emphasize the importance of patient-centred holistic care that can be provided through team-work

    A message emerging from development: the repression of mitochondrial β-F1-ATPase expression in cancer

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    The original publication is available at www.springerlink.com http://dx.doi.org/10.1007/s10863-007-9087-9Mitochondrial research has experienced a considerable boost during the last decade because organelle malfunctioning is in the genesis and/or progression of a vast array of human pathologies including cancer. The renaissance of mitochondria in the cancer field has been promoted by two main facts: (1) the molecular and functional integration of mitochondrial bioenergetics with the execution of cell death and (2) the implementation of 18FDG-PET for imaging and staging of tumors in clinical practice. The latter, represents the bed-side translational development of the metabolic hallmark that describes the bioenergetic phenotype of most cancer cells as originally predicted at the beginning of previous century by Otto Warburg. In this minireview we will briefly summarize how the study of energy metabolism during liver development forced our encounter with Warburg’s postulates and prompted us to study the mechanisms that regulate the biogenesis of mitochondria in the cancer cellThis review article was written while the research activity in the authors’ laboratory was supported by grants from the Ministerio de Sanidad (PI041255), Educación y Ciencia (SAF2005-4001) and Fundación Mutua Madrileña. The CBMSO is the recipient of an institutional grant from Fundación Ramón ArecesPeer reviewe

    Fluorine adsorption as well as fluorine and oxygen coadsorption on In-rich InSb(111) surface

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    The oxygen and fluorine adsorption and their coadsorption on the InSb(111)-(1×1) surface have been studied by the projector augmented-wave method within density functional theory. The indium top site was found to be the most energetically favorable for fluorine adsorption, whereas oxygen prefers to be bonded to the bridge site between two In atoms. It is shown that the oxygen-induced surface states are completely or partly removed from the band gap by fluorine coadsorption if it forms bonds with the indium atoms involved in an interaction with oxygen. An increase of fluorine concentration and its coadsorption bring about appreciable structural changes in the near-surface layers due to the penetration of both oxygen and fluorine atoms into the substrate

    Разработка и программная реализация механизма хранения и управления связями между объектами САПР БПО

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    Система автоматизированного проектирования бортового программного обеспечения (САПР БПО) должна решать задачи систематизации проектных данных об изделиях. Каждое изделие описывается в терминах САПР БПО и состоит из набора сложных информационных объектов, каждый из которых состоит из нескольких простых информационных объектов. Любой простой объект может входит в состав нескольких составных объектов. Целью работы является поиск методов и разработка средств поиска вхождения простых объектов в состав сложных, копирования сложных объектов из состава одного изделия в состав другого, удаления/модификации простых и сложных объектов с оценкой влияния на все изделия, в состав которых входит данный объект.The computer-aided design software for onboard software (CAD BPO) should solve the problem of systematization of design data about products. Each product is described in terms of CAD software and consists of a set of complex information objects, each of which consists of several simple information objects. Any simple object may be part of several composite objects. The aim of the work is to search for methods and develop tools for finding the entry of simple objects into complex, copying complex objects from one product into another, removing / modifying simple and complex objects with an assessment of the impact on all products that include this object

    Влияние ширины реза на осевую проекцию силы резания

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    В статье обосновывается влияние ширины реза на проекцию составляющей силы резания на ось вращения геохода. Рассмотрена актуальность исследования. Для постановки цели и задач исследования определена проекция составляющей силы резания на ось вращения геохода. На основании проведенного исследования построена зависимость осевой проекции силы резанию ножевого исполнительного органа геохода (Р0.СВ) от расстояния х на которое отдалена точка от оси вращения

    Геолого-промышленные типы месторождений германия, методика поисков и разведки

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    Recent genetic studies found the A allele of the variant rs1006737 in the alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene to be overrepresented in patients suffering from bipolar disorder, schizophrenia or major depression. While the functions underlying the pathophysiology of these psychiatric disorders are yet unknown, impaired performance in verbal fluency tasks is an often replicated finding. We investigated the influence of the rs1006737 single nucleotide polymorphism (SNP) on verbal fluency and its neural correlates.Brain activation was measured with functional magnetic resonance imaging (fMRI) during a semantic verbal fluency task in 63 healthy male individuals. They additionally performed more demanding verbal fluency tasks outside the scanner. All subjects were genotyped for CACNA1C rs1006737.For the behavioral measures outside the scanner, rs1006737genotype had an effect on semantic but not on lexical verbal fluency with decreased performance in risk-allele carriers. In the fMRI experiment, while there were no differences in behavioural performance, increased activation in the left inferior frontal gyrus as well as the left precuneus was found in risk-allele carriers in the semantic verbal fluency task.The rs1006737 variant does influence language production on a semantic level in conjunction with the underlying neural systems. These findings are in line with results of studies in bipolar disorder, schizophrenia and major depression and may explain some of the cognitive and brain activation variation found in these disorders
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