302 research outputs found
Regulating informal settlement âfrom withinâ: the case for plurality in applying building regulation to slum upgrading
In-situ upgrading of informal settlements has emerged as a key planning policy to provide durable housing that respects human rights and is financially viable. Slum upgrading policies usually focus on tenure legalisation and infrastructure improvements. However, we argue that such interventions miss a significant aspect by which informal settlements can be prevented from developing slum conditions â the application of building regulation. In conventional upgrading approaches, the application of building regulation has been conceived as a singular approach, in which city-wide, state-initiated building codes are adapted to the settlement. We broaden the debate on regulating informal settlement by incorporating regulation âfrom withinâ, which acknowledges that informal settlements are formed by sociospatial logics which are amenable to regulation by the dwellers themselves. This viewpoint discusses why urban regulation is needed in informal settlement upgrading, presents two of the broad critiques on the application of planning regulation to informal settlement, and suggests three approaches to regulating, namely âlowering standardsâ, ârelational rulesâ, and âneighbourly consentâ
Error rate and ergodic capacity of RF-FSO system with partial relay selection in the presence of pointing errors
This paper presents an analysis of a multiple dual-hop relaying system, which is composed of km-class radio frequency (RF)-free-space optical (FSO) links. Partial relay selection based on outdated channel state information (CSI) is employed in order to select active relay for further transmission. Amplify-and-forward relaying protocol is utilized. The RF links are assumed to be subject to Rayleigh fading, and the FSO links are influenced by both GammaâGamma atmospheric turbulence and pointing errors. On the basis of our previously derived expression for cumulative distribution function of the equivalent signal-to-noise ratio of the whole system, we derive novel analytical expressions for the average bit-error rate (BER) and ergodic capacity that are presented in terms of the Meijerâs G-function and extended generalized bivariate Meijerâs G-function, respectively. The numerical results are confirmed by Monte Carlo simulations. Considering the effect of time-correlation between outdated CSI and actual CSI related to the RF channel at the time of transmission, the average BER and the ergodic capacity dependence on various system and channel parameters are observed and discussed. The results illustrate that the temporal correlation between outdated and actual CSI has strong effect on system performance, particularly on BER values, when FSO hop is influenced by favorable conditions
The modified Glasgow prognostic score in prostate cancer: results from a retrospective clinical series of 744 patients
<p>Background: As the incidence of prostate cancer continues to rise steeply, there is an increasing need to identify more accurate prognostic markers for the disease. There is some evidence that a higher modified Glasgow Prognostic Score (mGPS) may be associated with poorer survival in patients with prostate cancer but it is not known whether this is independent of other established prognostic factors. Therefore the aim of this study was to describe the relationship between mGPS and survival in patients with prostate cancer after adjustment for other prognostic factors.</p>
<p>Methods: Retrospective clinical series on patients in Glasgow, Scotland, for whom data from the Scottish Cancer Registry, including Gleason score, Prostate Specific Antigen (PSA), C-reactive protein (CRP) and albumin, six months prior to or following the diagnosis, were included in this study.</p>
<p>The mGPS was constructed by combining CRP and albumin. Five-year and ten-year relative survival and relative excess risk of death were estimated by mGPS categories after adjusting for age, socioeconomic circumstances, Gleason score, PSA and previous in-patient bed days.</p>
<p>Results: Seven hundred and forty four prostate cancer patients were identified; of these, 497 (66.8%) died during a maximum follow up of 11.9Â years. Patients with mGPS of 2 had poorest 5-year and 10-year relative survival, of 32.6% and 18.8%, respectively. Raised mGPS also had a significant association with excess risk of death at five years (mGPS 2: Relative Excess Riskâ=â3.57, 95% CI 2.31-5.52) and ten years (mGPS 2: Relative Excess Riskâ=â3.42, 95% CI 2.25-5.21) after adjusting for age, socioeconomic circumstances, Gleason score, PSA and previous in-patient bed days.</p>
<p>Conclusions: The mGPS is an independent and objective prognostic indicator for survival of patients with prostate cancer. It may be useful in determining the clinical management of patients with prostate cancer in addition to established prognostic markers.</p>
A Compact Single Layer Reflectarray Antenna Based on Circular Delay-Lines for X-band Applications
This paper presents a compact single layer reflectarray antenna based on a diagonally notched square patch and a pair of circular delay lines, for X-band applications. The length and width of circular delay-lines are varied and optimized to attain a linear phase range of more than 600Âș. The effect of incident angle in TE and TM modes at 0Âș, 15Âș and 30Âș is studied, which offers stable angular phase range. The hybrid Finite Element Boundary Integral (FEBI) method is used for simulation of the whole reflectarray system comprising of 27 Ă 27 elements and being fabricated on a low cost FR-4 laminate. The measured gain of 24.5 dBi with aperture efficiency of 49.5% is achieved at 10 GHz. The proposed design provides the measured 1-dB gain bandwidth of 12.5% and 3-dB gain bandwidth of 34%. The simulated and measured side-lobe-levels and cross polarizations are less than â25 dB and â40 dB respectively
Verification of Semantic Commutativity Conditions and Inverse Operations on Linked Data Structures
Commuting operations play a critical role in many parallel computing systems. We present a new technique for verifying commutativity conditions, which are logical formulas that characterize when operations commute. Because our technique reasons with the abstract state of verified linked data structure implementations, it can verify commuting operations that produce semantically equivalent (but not identical) data structure states in different execution orders. We have used this technique to verify sound and complete commutativity conditions for all pairs of operations on a collection of linked data structure implementations, including data structures that export a set interface (ListSet and HashSet) as well as data structures that export a map interface (AssociationList, HashTable, and ArrayList). This effort involved the specification and verification of 765 commutativity conditions. Many speculative parallel systems need to undo the effects of speculatively executed operations. Inverse operations, which undo these effects, are often more efficient than alternate approaches (such as saving and restoring data structure state). We present a new technique for verifying such inverse operations. We have specified and verified, for all of our linked data structure implementations, an inverse operation for every operation that changes the data structure state. Together, the commutativity conditions and inverse operations provide a key resource that language designers and system developers can draw on to build parallel languages and systems with strong correctness guarantees
Coffee consumption and prostate cancer risk: further evidence for inverse relationship
<p>Abstract</p> <p>Background</p> <p>Higher consumption of coffee intake has recently been linked with reduced risk of aggressive prostate cancer (PC) incidence, although meta-analysis of other studies that examine the association between coffee consumption and overall PC risk remains inconclusive. Only one recent study investigated the association between coffee intake and grade-specific incidence of PC, further evidence is required to understand the aetiology of aggressive PCs. Therefore, we conducted a prospective study to examine the relationship between coffee intake and overall as well as grade-specific PC risk.</p> <p>Methods</p> <p>We conducted a prospective cohort study of 6017 men who were enrolled in the Collaborative cohort study in the UK between 1970 and 1973 and followed up to 31st December 2007. Cox Proportional Hazards Models were used to evaluate the association between coffee consumption and overall, as well as Gleason grade-specific, PC incidence.</p> <p>Results</p> <p>Higher coffee consumption was inversely associated with risk of high grade but not with overall risk of PC. Men consuming 3 or more cups of coffee per day experienced 55% lower risk of high Gleason grade disease compared with non-coffee drinkers in analysis adjusted for age and social class (HR 0.45, 95% CI 0.23-0.90, p value for trend 0.01). This association changed a little after additional adjustment for Body Mass Index, smoking, cholesterol level, systolic blood pressure, tea intake and alcohol consumption.</p> <p>Conclusion</p> <p>Coffee consumption reduces the risk of aggressive PC but not the overall risk.</p
Women and Networking: A Systematic Literature Review (1985-2021)
This report analyses literature on women and networking between 1985 and 2021, as published in women and gender studies journals. Authors analysed a total of 78 articles published in European Journal of Womenâs Studies, Feminist Review, Womenâs Studies International Forum, Feminist Theory, Gender & Society, Journal of Gender Studies, Frontiers: A Journal of Women Studies, Signs, Women Studies Quarterly, Feminist Economics, Gender in Management: An International Journal (previously called Women in Management Review,), Gender, Work & Organization, Feminist Studies, Hypatia and International Journal of Gender and Entrepreneurship. Thematic analysis and three-tier coding have been used in analysing available articles. Findings reveal that organisational cultures did not change during the four decades of research as boys clubs still exist and take men ahead much more than womenâs networks take women ahead. Old boys clubs remain persistent and more powerful than womenâs networks and women do not report benefits from networking even when they engage with this, often seen, masculine practice. Women also report exclusion from important professional networks and this is a theme that consistently runs through research, and additionally, many women cannot join networks due to the social expectation that women will look after families. Networking thus presents a structural barrier and this is visible throughout decades of analysed research, with recurring and repeating themes of networking as a structural barrier, exclusion of women and persistent power and influence of old boys clubs
A comparative study to evaluate the effects of antibiotics, plant extracts and fluoride-based toothpaste on the oral pathogens isolated from patients with gum diseases in Pakistan
Oral diseases caused by various microorganisms are common around the world. Scientific research has now been focusing on novel medicines to overcome bacterial resistance and antibiotics side effects; therefore, the current study was designed to assess the efficacy of certain antibiotics, toothpaste, and medicinal plant extracts (Ajuga bracteosa and Curcuma longa) versus the bacterial pathogens isolated from the human oral cavity. A total of 130 samples were collected from Khyber Teaching Hospital Peshawar, Pakistan, among those 27 species isolated, and eight bacterial species were identified from the samples. Among all the bacterial species, Staphylococcus aureus (29.62%) and Proteus mirabilis (22.2%) were found to be more prevalent oral pathogens. In comparison, the least pervasive microbes were Proteus vulgaris, Shigella sonnei, Escherichia coli and Aeromonas hydrophila. The study also suggested that dental problems were more prevalent in males (41-50 years of age) than females. Among the eight antibiotics used in the study, the most promising results were shown by Foxicillin against A. hydrophila. The survey of TP1 revealed that it showed more potent antagonist activity against Proteus vulgaris as compared TP2 and TP3 that might be due to the high content of fluoride. The Curcuma longa showed more significant activity than Ajuga bracteosa (Stem, leaves and root) extracts. The data obtained through this study revealed that antibiotics were more effective for oral bacterial pathogens than toothpaste and plant extracts which showed moderate and low activity, respectively. Therefore, it is suggested that the active compounds in individual medicinal plants like Curcuma longa and Ajuga bracteosa could replace the antibiotics when used in daily routine as tooth cleansers or mouth rinses
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