FoMO ile nomofobi arasındaki ilişkide sosyal medya kullanım alışkanlıklarının aracı rolü

This study examines the mediating role of social media usage habits in the relationship between FoMO and nomophobia. 457 people were recruited to participate in the study. While 177 of them were male, the remaining 280 participants were female, and the participants’ age ranged between 18 and 70. The average age of the participants was calculated as 30.81. The research hypotheses were tested by hierarchical regression analysis. In addition, the significance of the mediator variable was examined via Bootstrapping analysis. First, Pearson productmoment correlation analysis was performed to determine the relationship between variables, and it was found that there was a positive significant relationship between variables. The subsequent hierarchical regression analysis determined that social media usage habits played a partial mediating role in the relationship between FoMO and nomophobia. All findings were discussed in the light of similar research studies in the existing literature, and several suggestions were provided in the end.Bu çalışmada, FoMO ile nomofobi arasındaki ilişkide sosyal medya kullanım alışkanlıklarının aracı rolünün incelenmesi amaçlanmıştır. Araştırmanın çalışma grubu, yaşları 18 ile 70 arasında değişen 177’si erkek ve 280’i kadın olmak üzere toplam 457 kişiden oluşmaktadır. Katılımcıların yaş ortalaması ise 30.81 olarak hesaplanmıştır. Araştırmanın hipotezleri hiyerarşik regresyon analizi ile test edilmiştir. Ayrıca aracı değişkenin anlamlılığı günümüzde daha çağdaş bir yaklaşım olarak kabul gören Bootstrapping yöntemi ile hesaplanmıştır. Veri analizinde ilk olarak değişkenler arasındaki ilişkiyi belirlemek amacıyla Pearson momentler çarpımı korelasyon analizi yapılmış ve değişkenler arasında pozitif yönde anlamlı ilişkiler olduğu ortaya konmuştur. Sonrasında yapılan hiyerarşik regresyon analizinde sosyal medya kullanım alışkanlıkları değişkeninin FoMO ile nomofobi arasındaki ilişkide kısmi aracı rol oynadığı belirlenmiştir. Alanyazında FoMO ile nomofobi arasındaki ilişkide sosyal medya kullanım alışkanlıkları değişkeninin aracı rolünün incelendiği herhangi bir çalışma olmaması, bu araştırmanın önemini ortaya koymaktadır. Elde edilen tüm bu bulgular benzer çalışmalar ve alanyazın ışığında tartışılmış, tüm okuyuculara bazı önerilerde bulunulmuştur

Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation

The role of oxidative stress, as well as inflammation in the pathogenesis of methotrexate (MTX)-induced oral mucositis, is a known fact. The anti-inflammatory, antitumor, antimicrobial, and antioxidant properties of taxifolin—the effect we tested against MTX-induced oral mucosal damage—are well known. Objective: Evaluating biochemically and histopathologically the effects of taxifolin on methotrexate-induced oral mucosal damage in rats. Methodology: In the taxifolin+MTX (TMTX) group, 50 mg/kg taxifolin was orally administered to rats by gavage. In the MTX and healthy (HG) groups, normal saline was applied to rats as solvent by the same method. One hour after administration of taxifolin and solvent, 5 mg/kg MTX was orally administered to rats in the MTX and TMTX groups. Taxifolin and methotrexate were administered once a day for 30 days. Macroscopic, biochemical, and histopathological evaluations were performed on the inner cheek and tongue tissues of rats. These parts were removed after rats were killed with a high-dose anesthesia. Results: Taxifolin with MTX prevented the increase in oxidant and pro-inflammatory parameters, such as malondialdehyde (MDA), tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), interleukin 6 (IL-6), on the inner cheek and tongue tissues of rats. Moreover, taxifolin antagonized the decrease in total glutathione (tGSH). Taxifolin decreased MTX-induced histopathological damage. Conclusion: These findings suggest that taxifolin may be useful to treat MTX-associated oral mucositis

The effects of taxifolin on neuropathy related with hyperglycemia and neuropathic pain in rats: A biochemical and histopathological evaluation

Background. Hyperglycemia can be considered a determining factor in the development of diabetic neuropathy as well as neuropathic pain. There is a relationship between the excessive production of reactive oxygen species (ROS) and the pathogenesis of diabetic neuropathic pain. Taxifolin, on the other hand, is a flavonoid that has been documented to inhibit ROS production. Objectives. To investigate the effects of taxifolin, which has antioxidant and neuroprotective effects, on alloxan-induced hyperglycemia-induced neuropathy and neuropathic pain, biochemically and histopathologically. Materials and methods. The albino Wistar male rats were divided into 3 groups: Healthy group (HG), only alloxan group (AXG) and alloxan+taxifolin group (ATG). Hyperglycemia in animals was caused through intraperitoneal injection of alloxan at a dose of 120 mg/kg. Paw pain thresholds of animals were measured using Basile algesimeter. Sciatic nerve tissues were examined biochemically and histopathologically in order to evaluate neuropathy. Results. Our experimental results revealed that taxifolin significantly prevented the increase of plasma glucose concentration level with alloxan administration, the decrease of the paw pain threshold related to hyperglycemia, the change of oxidant-antioxidant balance in the sciatic nerve tissue in favor of oxidants, and the deterioration of tissue morphology in animals. Conclusions. Our experimental results indicate that taxifolin alleviates alloxan-induced hyperglycemia-related neuropathy and neuropathic pain

Protective effect of cinnamon extract against cobalt-induced multiple organ damage in rats

BackgroundThe role of oxidative stress and inflammation in cobalt (Co) toxicity has been the focus of previous studies. Cinnamon and its main components have been reported to have protective effects in various tissues with antioxidant and anti-inflammatory effects.AimsIn this study, the protective effect of cinnamon extract (CE) against possible Co-induced heart, kidney, and liver damage in rats was investigated biochemically.MethodsEighteen albino Wistar-type male rats were categorized into three groups (n = 6 per group): control (CG), CoCL2-administered (CoCL2), and CE + CoCL2-administered (CE + Co) groups. The CE + CoCL2 group was administered CE (100 mg/kg), and the CoCL2 and CG groups were administered distilled water orally by gavage. One hour after the administration, Co (150 mg/kg) was administered orally to the CE + CoCL2 and CoCL2 groups. This procedure was repeated once daily for 7 days. Then, biochemical markers were studied in the excised heart, kidney, and liver tissues.ResultsCoCL2 increased oxidants and proinflammatory cytokines and decreased antioxidants in heart, kidney, and liver tissues. Heart, kidney, and liver tissue were affected by Co damage. CE treatment suppressed the CoCL2-induced increase in oxidants and proinflammatory cytokines and decrease in antioxidants in heart, kidney, and liver tissues. CE treatment has been shown to attenuate cardiac damage by reducing serum troponin I (TpI) and creatine kinase-MB (CK-MB), renal damage by reducing creatinine and blood urea nitrogen (BUN), and liver damage by reducing alanine aminotransferase (ALT) and aspartate aminotransferase (AST).ConclusionCo induced the production of oxidants and proinflammatory parameters and antioxidant depletion in heart, kidney, and liver tissues of rats. Our experimental results show that CE protects heart, kidney, and liver tissues against oxidative and inflammatory changes induced by CoCLl2

Lacidipine, thiamine pyrophosphate and their combination on the ocular ischemic syndrome induced by bilateral common carotid artery ligation

AIM: To investigate the effect of lacidipine, thiamine pyrophosphate (TPP) and the combination of lacidipine and TPP against oxidative and inflammatory eye damage induced by bilateral common carotid artery ligation in rats. METHODS: Male albino Wistar rats were categorized as those who underwent sham surgery (SG), right and left common carotid cross-clamping and unclamping procedure (CCU), lacidipine+CCU (LCCU), TPP+CCU (TCCU), and combination of lacidipine and TPP (LTC)+CCU (LTCCU). One hour before anesthesia, the LCCU (n=6) received lacidipine (4 mg/kg, orally) and the TCCU (n=6) received TPP (20 mg/kg, intraperitoneally). The SG (n=6) and CCU (n=6) received the same volume of distilled water from the same route. After anesthesia (60 mg/kg ketamine, intraperitoneally), the necks of the rats were opened in the midline. Ischemia was created for 10min by placing clips on the right and left common carotid arteries. Rats in the SG only underwent subcutaneous incision. After 10min, the clips were removed and reperfusion was achieved for six days. Then, the animals were euthanized (120 mg/kg ketamine, intraperitoneally) and the levels of oxidant, antioxidant and proinflammatory cytokines in the eye tissues were determined. The retinal tissue of the eye was also examined histopathologically. RESULTS: Lacidipine, TPP, and LTC significantly prevent the increase in malondialdehyde, tumor necrosis factor-alpha, interleukin-1β (IL-1β), and IL-6 levels, decrease in total glutathione levels, superoxide dismutase and catalase activities and histopathological retinal damage in eye tissue induced by bilateral common carotid artery ligation in rats. The impact of these drugs on protection is determined to be LTC>lacidipine>TPP. CONCLUSION: As a result of the study, it is concluded that LTC may be more effective than lacidipine and TPP alone in treating ocular ischemic syndrome

İris görüntülerinin analiziyle kimlik tanıma

İRİS GÖRÜNTÜLERİNİN ANALİZİYLE KİMLİK TANIMA Günümüz teknolojisinde ek güvenlik ihtiyaçlarına cevap verebilen biyometrik sistemler, kişilerin ve biyolojik ürünlerin sahip olduğu, özgün fiziksel ve davranışsal özellikleri kullanan bir örüntü eşleme sistemidir. Biyometrik sistemler, şifre hatırlama ya da kimlik taşıma gibi ihtiyaçlara gerek duymadan, sadece kişiye ait olan özellikleri kullanır. Bu sistemler kişiye ait bilgileri kaydedip bir veritabanı oluştururlar ve daha sonra her güvenlik sorgulamasında kullanırlar. Bu tez kapsamında yaşam boyu kararlı olması, ayrıt edici özelliklerinin diğer biyometrik tekniklere göre çok daha fazla olması, iyi korunan iç organ olması,taklit edilmesinin imkansız olması,uzaktanda görülebilmesi, yüksek rastgeleliğe sahip olması, genetik benzerliğin azlığı, görüntü alınırken herhangi bir temas olmadan kolayca alınabilmesigibi nedenlerden dolayı irisi temel alan bir biyometrik tanıma sistemi üzerinde çalışılmıştır. Sistemde kullanılan veritabanındaki imgelerden iris bölgesinin elde edilebilmesi için, Canny kenar bulma algoritması ve Hough transformu kullanılmıştır. Alınan göz imgelerinde kestirilen iris imgesi kutupsal formdan dikdörtgen forma dönüştürülmüştür. Normalleştirilmiş iris deseni Gabor dalgacıkları ile konvolve edilmesiyle öznitelik çıkarım işlemi gerçekleştirilmiş ve filtre çıkışındaki gürültünün etkisini önlemek için çevrelenmiş piksellerin yoğunlukları ortalama olarak alınmıştır. Her bir fazör için iki data biti üreten her bir filtreyle faz dört seviyeye quantize edilmiştir. Son olarak eşleştirme için bitsel karşılaştırmalar gerekli olduğundan Hamming uzaklığı kullanılmıştır.Çalışma sürecinde filtrelemeler, görüntü işleme gibi kullanılan süreçlerin tümü MATLAB ortamında gerçekleştirilmiştir. Bu tez çalışmasında gerçekleştirilen sistemin performansını test etmek için ROC analizi yapılmıştır. Analiz sonuçlarına göre, geliştirilen sistem kimlik tanımlama hassasiyeti ile tatmin edici sonuç sağlamıştır. ABSTRACT IDENTITY RECOGNITION TROUGH ANALYSIS OF IRIS IMAGES Biometric systems which can response to additional security needs in peresent technology, is an image matching systems which uses original physcal and behavioral properties of which people their biological products have. Biometric systems use only properties of person, therefore remembering password or carrying ID card is not required. These systems record the personal information and make up a database, and then used for every security inquiry. In the scope of this thesis studies have been implemented for iris recognation systems based on iris which is accepted as one of the most reliable biometric characteristics due to reasons like its highes discrimination ratio between human beings, being a well-protected internal organ, being impossible to imitate, low genetical likeness and no contact while capturing the image. Canny edge detection algorithm and Hough transform have been used in order to obtain iris recognation from the images in the database. Iris image extracted from eye. Images have been trcensformed from polar form to rectangular form. In order to obtain the iris zone from the pictures on the data base used on the system, Canny edge detection algorithm and Hough transform were used. The iris picture which was cut at received eye pictures was transformed from circular form into rectangular form. Normalized iris design was convoluted by Gabor ripples and so, self-quality deduction procedure was obtained and, in order to prevent the effect of the noise at the filter outlet, the density of the surrounded pixels was taken on an average. The phase was encoded to four levels by each filter generating two data bits for each phaser. And finally, Hamming distance was used since bit comparisons were necessary for matching. During the study, all the processes such as filtrations, picture processing etc were done at MATLAB environment. ROC analysis has been carried out in order to test the performance of the thesis study. According to the analysis reports, the developed system has been provided satisfying results through ID recognition precision

İris görüntülerinin analiziyle kimlik tanıma

ÖZETİRİS GÖRÜNTÜLERİNİN ANALİZİYLE KİMLİK TANIMAGünümüz teknolojisinde ek güvenlik ihtiyaçlarına cevap verebilen biyometrik sistemler, kişilerin ve biyolojik ürünlerin sahip olduğu, özgün fiziksel ve davranışsal özellikleri kullanan bir örüntü eşleme sistemidir. Biyometrik sistemler, şifre hatırlama ya da kimlik taşıma gibi ihtiyaçlara gerek duymadan, sadece kişiye ait olan özellikleri kullanır. Bu sistemler kişiye ait bilgileri kaydedip bir veritabanı oluştururlar ve daha sonra her güvenlik sorgulamasında kullanırlar.Bu tez kapsamında yaşam boyu kararlı olması, ayrıt edici özelliklerinin diğer biyometrik tekniklere göre çok daha fazla olması, iyi korunan iç organ olması,taklit edilmesinin imkansız olması,uzaktanda görülebilmesi, yüksek rastgeleliğe sahip olması, genetik benzerliğin azlığı, görüntü alınırken herhangi bir temas olmadan kolayca alınabilmesigibi nedenlerden dolayı irisi temel alan bir biyometrik tanıma sistemi üzerinde çalışılmıştır. Sistemde kullanılan veritabanındaki imgelerden iris bölgesinin elde edilebilmesi için, Canny kenar bulma algoritması ve Hough transformu kullanılmıştır. Alınan göz imgelerinde kestirilen iris imgesi kutupsal formdan dikdörtgen forma dönüştürülmüştür. Normalleştirilmiş iris deseni Gabor dalgacıkları ile konvolve edilmesiyle öznitelik çıkarım işlemi gerçekleştirilmiş ve filtre çıkışındaki gürültünün etkisini önlemek için çevrelenmiş piksellerin yoğunlukları ortalama olarak alınmıştır. Her bir fazör için iki data biti üreten her bir filtreyle faz dört seviyeye quantize edilmiştir. Son olarak eşleştirme için bitsel karşılaştırmalar gerekli olduğundan Hamming uzaklığı kullanılmıştır.Çalışma sürecinde filtrelemeler, görüntü işleme gibi kullanılan süreçlerin tümü MATLAB ortamında gerçekleştirilmiştir.Bu tez çalışmasında gerçekleştirilen sistemin performansını test etmek için ROC analizi yapılmıştır. Analiz sonuçlarına göre, geliştirilen sistem kimlik tanımlama hassasiyeti ile tatmin edici sonuç sağlamıştır.ABSTRACTIDENTITY RECOGNITION TROUGH ANALYSIS OF IRIS IMAGESBiometric systems which can response to additional security needs in peresent technology, is an image matching systems which uses original physcal and behavioral properties of which people their biological products have. Biometric systems use only properties of person, therefore remembering password or carrying ID card is not required. These systems record the personal information and make up a database, and then used for every security inquiry.In the scope of this thesis studies have been implemented for iris recognation systems based on iris which is accepted as one of the most reliable biometric characteristics due to reasons like its highes discrimination ratio between human beings, being a well-protected internal organ, being impossible to imitate, low genetical likeness and no contact while capturing the image.Canny edge detection algorithm and Hough transform have been used in order to obtain iris recognation from the images in the database. Iris image extracted from eye. Images have been trcensformed from polar form to rectangular form. In order to obtain the iris zone from the pictures on the data base used on the system, Canny edge detection algorithm and Hough transform were used. The iris picture which was cut at received eye pictures was transformed from circular form into rectangular form. Normalized iris design was convoluted by Gabor ripples and so, self-quality deduction procedure was obtained and, in order to prevent the effect of the noise at the filter outlet, the density of the surrounded pixels was taken on an average. The phase was encoded to four levels by each filter generating two data bits for each phaser. And finally, Hamming distance was used since bit comparisons were necessary for matching. During the study, all the processes such as filtrations, picture processing etc were done at MATLAB environment.ROC analysis has been carried out in order to test the performance of the thesis study. According to the analysis reports, the developed system has been provided satisfying results through ID recognition precision

EVALUATION OF WOMEN'S BELIEFS ABOUT PAP SMEAR SCREENING USING THE HEALTH BELIEF MODEL SCALE

Objective: To evaluate women's beliefs about screening Pap smear test