Comparison of two different labial salivary gland biopsy incision techniques: a randomized clinical trial

Objectives: To compare the reliability of two different labial salivary gland biopsy (LSGB) incision techniques (vertical versus horizontal incision techniques) and to report the related complications and discomfort. Study Design: 163 patients who underwent LSGB were included in this study. Patients were randomly divided as vertical incision group (n=81) and horizontal incision group (n=82). Demographic and clinical information of each patient were recorded. A questionnaire was prepared and applied together with Visual Analog Scale (VAS) on the subjects verbally at the 7th day, postoperatively. Intraoperative, short- term and delayed complications were evaluated. Results: The mean age of patients (117 female, 46 male) was 47.3 years (range 19-79 years). Vertical incision technique was associated with less pain (p<0.001), less swelling (p<0.05), less scar formation (p<0.05) and less difficulty in eating (p<0.05) when compared with horizontal incision technique. No statistically significant differences were observed between the 2 groups in terms of hematoma, parasthesia and speech difficulty (p>0.05). Additionally, two subjects in the horizontal incision group revealed permanent paresthesia during the follow-up period of two years. Conclusions: This prospective study demonstrated that the subjects in the vertical incision group had less complication rates and discomfort after labial salivary gland procedure than those in the horizontal incision group

An evaluation of the efficacy of a topical gel with Triester Glycerol Oxide (TGO) in the treatment of minor recurrent aphthous stomatitis in a Turkish cohort : a randomized, double-blind, placebo-controlled clinical trial

Triester glycerol oxide gel (Protefix® Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation. The aim of this clinical trial was to determine the efficacy of a topical TGO gel and to also compare it with triamcinolone acetonide pomade in the treatment of minor recurrent aphthous stomatitis. This study was a randomized, double-blind, placebo-controlled clinical trial and 180 patients with the complaint of minor aphthous ulcers were enrolled in this study. The sociodemographic data and clinical characteristics of the ulcer were collected by questionnaire. Ulcer size and pain level measurements were performed and the efficacy indices for ulcer pain and size were calculated at day 0,2,4,6 by the same investigator. Significant differences were not detected among the demographics and ulcer histories including age, gender, onset of ulcer, mean healing time, family RAS history and ulcer localization between three groups. The pain score in TGO group was found statistically lower at day 2,4, and 6. Efficacy index and improvement rate of TGO group, regarding pain score, was higher than the other two groups at day 2 and 4. The reduction in ulcer size was statistically higher in TGO group than the other two groups at day 4 and 6. Topical application of TGO gel could decrease pain intensity, accelerate ulcer healing without any side effects, utilizing an easy appliable and accessible procedure. Therefore TGO gel could be a well-tolerated, safe, topical therapeutic agent in the clinical practice of RAS treatment

Acinic Cell Carcinoma of the Lower Lip: a Case Report

Karcinom acinusnih stanica rijetka je bolest – to je tumor žlijezda slinovnica niskog stupnja malignosti. Najčešće se nalazi u velikim žlijezdama slinovnicama, gotovo uvijek u parotidnoj žlijezdi, a rijetko u malim žlijezdama slinovnicama. U ovom opisu predstavljamo slučaj muškarca u dobi od 64 godine s perzistentnom dvogodišnjom oteklinom u sluznici donje usnice u ravnini očnjaka. Lezija je bila bezbolna, meke teksture, nalikovala je na mukokelu, bila je veličine 1x1,5 cm te pokrivena sluznicom normalne boje. Kirurški je uklonjena te je histopatološki potvrđen karcinom acinusnih stanica.Acinic cell carcinoma is a rare, low grade malignant tumor of the salivary glands. Most frequently it originates from major salivary glands almost exclusively in parotid gland and rarely from minor salivary glands. In this report we present a case of 64-year-old man with a persistent swelling within the mucosa of the lower lip at the line of the canine tooth for two years. The lesion was painless, soft in texture, mimicked a mucocel and had the dimensions of 1x1.5 cm with an overlying mucosa normal in color. Surgical excision of the lesion is performed and histopathological confirmation revealed acinic cell carcinoma

Surgical Management of Overfilling of a Root Canal Filling Material: a Case Report

U radu je predstavljeno kirurško liječenje u slučaju kad su bol i oteklina bili uzrok izlaska materijala za punjenje korijenskog kanala u veliku periapikalnu leziju između lateralnog sjekutića i očnjaka lijeve maksile. Oteklina je bila bolna na dodir. Lezija i materijal kirurški su uklonjeni. Da je sve potpuno zacijelilo, zaključeno je radiološki na postoperativnom pregledu godinu dana nakon zahvata. Kirurška intervencija velikih periapikalnih lezija indicirana je ako se nehotice dogodi da izađu velike količine materijala za punjenje korijenskih kanala, kako bi se omogućilo cijeljenje periradikularnog tkiva.The surgical treatment of a case presenting pain and swelling due to the extrusion of the root canal filling into a large periapical lesion between left maxillary lateral and canine teeth is presented in this report. The swelling was painful on palpation. Removal of the lesion and the material was made surgically. Complete healing was observed at the postoperative first year radiographically. Surgical intervention of large periapical lesions is indicated in cases in which the extrusion of large amount of root canal filling material occurred inadvertently to provide healing of the periradicular tissues