75 research outputs found

    Hydrogels based on poly(vinyl alcohol) for cartilage substitution

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    Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

    Effect of the saliva biomolecules on the interface zirconia/Ti6Al4V triboactivity

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    Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

    Interaction of fluorescence of resin cements with glass ceramics

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    Poster presented at the 24th Annual Meeting of the Portuguese Dental Association, Lisbon, 12-14 November 2015.Poster apresentado no XXIV Congresso da Ordem dos Médicos Dentistas, Lisboa, 12-14 Novembro 2015."Introduction: In aesthetic rehabilitations, we must take into account the primary and secondary optical properties. Objectives: To evaluate the emission intensity of fluorescence between resin cement and glass-ceramic. Materials and Methods: two self-adhesive resin cements were used, as well as glass ceramic discs and composite resin. The ceramic cylinders were cut with a thickness of 1 and 0.5 millimeters and were bonded to composite resin discs with 0.5mm and polymerized for 40 seconds, for a total of n = 100. Fluorescence spectrums were obtained in a spectrofluorometer at a wavelength of 380 nanometers. Statistical analysis was performed using Student's t-test and one-way ANOVA, for a significance of p <0.05. Results: The samples of the control group were the ones who exhibited lower fluorescence with values of 1.99E13 a.u. in a thickness of 0.5mm and 2.95E13 a.u. in a thickness of 1 mm. In the samples of 1mm, all groups have similar values of fluorescence emission. In samples with 0.5mm, there are significant differences between each group (p <0.001) , in which the SCT group has higher fluorescence emission (1.06E14 a.u.). Conclusions: The thickness of the ceramic influences the final emission intensity of fluorescence. The emission intensity of fluorescence of the resin cements influences the final fluorescence of the glass ceramic. Clinical Implications: This study reveals the importance of the choice of the cement and ceramic thickness in a full ceramic rehabilitation.

    Physically crosslinked polyvinyl alcohol hydrogels as synthetic cartilage materials

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    Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

    Sterilization of ophthalmic drugs and intraocular lenses

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    Poster presented at the First International Congress of CiiEM - From Basic Sciences to Clinical Research. 27-28 November 2015, Egas Moniz, Caparica, PortugalFundação para a Ciência e a Tecnologia: projects UID/QUI/00100/2013 and M-ERA.NET/0005/201

    Effect of pH of H2O2 solutions on the morphology and wear resistance of human dental enamel: an AFM study

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    Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

    Effect of sterilization on drugs and lenses for ophthalmic applications

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    Poster presented at the 10th World Biomaterials Congress. Montreal, Canada, 17-22 May 2016N/

    3D-Printing of zirconia dental prostheses

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    Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

    In vitro controlled drug release from contact lenses materials under physiological ocular tear flow

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    Poster presented at the 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Lisbon, 31 March-3 April 2014.BASF; Fundação para a Ciência e a Tecnologi

    Effect of tetracaine on DMPC and DMPC + cholesterol biomembrane models: Liposomes and monolayers

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    “NOTICE: this is the author’s version of a work that was accepted for publication in Colloids and Surfaces B: Biointerfaces. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Colloids and Surfaces B: Biointerfaces, [Vol. 16, (April 2014)] DOI 10.1016/j.colsurfb.2013.12.042 ""Different types of lipid bilayers/monolayers have been used to simulate the cellular membranes in the investigation of the interactions between drugs and cells. However, to our knowledge, very few studies focused on the influence of the chosen membrane model upon the obtained results. The main objective of this work is to understand how do the nature and immobilization state of the biomembrane models influence the effect of the local anaesthetic tetracaine (TTC) upon the lipid membranes. The interaction of TTC with different biomembrane models of dimyristoylphosphatidylcholine (DMPC) with and without cholesterol (CHOL) was investigated through several techniques. A quartz crystal microbalance with dissipation (QCM-D) was used to study the effect on immobilized liposomes, while phosphorus nuclear magnetic resonance (31P-NMR) and differential scanning calorimetry (DSC) were applied to liposomes in suspension. The effect of TTC on Langmuir monolayers of lipids was also investigated through surface pressure-area measurements at the air-water interface. The general conclusion was that TTC has a fluidizing effect on the lipid membranes and, above certain concentrations, induced membrane swelling or even solubilization. However, different models led to variable responses to the TTC action. The intensity of the disordering effect caused by TTC increased in the following order: supported liposomes < liposomes in solution < Langmuir monolayers. This means that extrapolation of the results obtain in in vitro studies of the lipid/anaesthetic interactions to in vivo conditions should be done carefully.
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