Implementing an e-business model for a dot-com SME: Lessons Learned

One of the key steps to develop an e-business solution is the definition of a Business Model (BM), which requires the expertise from different areas such as finance, technology, marketing, and project management. It is known that Small and Medium Enterprises (SMEs) count with limited resources to undertake this type of e-business initiatives, and thus prompt to failure. This paper tells the story of the process of selection of a BM (and related documents) needed for the design and implementation of an undergoing dot-com initiative leaded by an SME in Mexico. The results of such study are summarized in a series of recommendations that SME may found useful when embarking in similar projects. Some key findings from these recommendations are: partnership with academic/research institutions, the key role of project management, communication, and identification of links between strategy and technology

Absorptive Capacity and its Potential Role in Supporting Organisational knowledge Creation: A Qualitative Approach

Absorptive Capacity (ACAP) is the ability of a firm to integrate, transform, and apply valuable knowledge required for business success. ACAP is proposed to play a significant role in enriching the process of knowledge creation embraced inside contemporary organizational Information Systems (IS) environments. Many misperceptions surround how ACAP can be measured and understood as an organizational construct. The aim of this research is to decrease such misperception by providing qualitative measures for ACAP dimensions extracted using data from (22) semi-structured interviews conducted with senior managers working in two telecommunication companies, and analysed following Grounded Theory Methodology (GTM) coding techniques. Drawing on our analysis, we propose a relational model that includes measures that can be commonly used in the literature, and treated as guides to IS researchers and senior managers in exploring the rich facets of ACAP. The extracted measures are proposed to offer foundations for shaping where and how further potential organizational assets can be leveraged

Association Between Glycated Albumin, Fructosamine, and HbA1c with Neonatal Outcomes in a Prospective Cohort of Women with Gestational Diabetes Mellitus

Objective: To investigate whether glycated albumin, fructosamine, and hemoglobin A1c (HbA1c) are associated with neonatal complications in newborns of pregnant women with gestational diabetes mellitus (GDM). Methods: Between November 2016 and September 2017, women with a singleton pregnancy and GDM were enrolled in a prospective study in an obstetric Portuguese referral center. Glycemic markers were compared between mothers of newborns with and without complications. Multivariable logistic regression models and corresponding areas under the receiver operating characteristic curve (AUC) were used. Results: A total of 85 women participated in the study. Raised levels of glycated albumin and fructosamine were associated with at least one neonatal complication (OR- [odds ratio] estimate: 1.33, P=0.015; OR: 1.24, P=0.027, respectively) and with respiratory disorders at birth (OR 1.41, P=0.004; OR 1.26, P=0.014, respectively). HbA1c was not associated with these outcomes. All biomarkers were associated with large-for-gestational age (LGA) status (OR 1.61, P<0.001; OR 1.45, P<0.001; OR 3.62, P=0.032 for glycated albumin, fructosamine, and HbA1c, respectively). All had similar AUC for at least one neonatal complication (0.82; 0.81; 0.79, respectively). For newborn respiratory disorders, AUCs were 0.83, 0.81, and 0.76, respectively, and for LGA status were 0.81, 0.79, and 0.71, respectively. Conclusion: Raised values of glycated albumin and fructosamine were associated with particular perinatal complications in newborns of mothers with GDM, better discriminating mothers of newborns with and without complications than HbA1c.info:eu-repo/semantics/publishedVersio

A study on the internal convection in small turbochargers. Proposal of heat transfer convective coefficients

Nowadays turbochargers play an important role in improving internal combustion engines (ICE) performance. Usually, engine manufacturers use computer codes to predict the behaviour of both engine and turbocharger, the later by means of measured look-up maps. Using look-up maps different problems arise, being one of the most important the difference in heat transfer between the current operating condition and the conditions at which maps were measured. These effects are very important at low to medium turbocharger speeds (typical condition of urban driving conditions) where heat transfer can even be higher than mechanical power. In this work, the different convective heat transfer phenomena inside these kind of machines have been measured and analysed. Besides, general correlations for these flows, based on dimensionless numbers, are fitted and validated in three different turbochargers. The applicability of the model is shown by comparison the main results obtained when the model is used and not, improving up to 20 C the predicted turbine outlet temperature. The main advantages of applying these correlations rely on predicting fluids outlet temperatures (compressor, turbine, oil and coolant). The former is needed to feed accurately ICE model, turbine outlet temperature is important for aftertreatment device modelling while oil and coolant temperatures are important in order to design optimum cooling systems.This work has been partially supported by the Spanish Ministerio de Economa y Competitividad through grant no. TRA2012-36954. The equipment used in this work has been partially supported by FEDER project funds "Dotacion de infraestructuras cientifico tecnicas para el Centro Integral de Mejora Energetica y Medioambiental de Sistemas de Transporte (CiMeT), (FEDER-ICTS-2012-06)", framed in the operational program of unique scientific and technical infrastructure of the Ministry of Science and Innovation of Spain.Serrano Cruz, JR.; Olmeda González, PC.; Arnau Martínez, FJ.; Reyes Belmonte, MÁ.; Tartoussi, H. (2015). A study on the internal convection in small turbochargers. Proposal of heat transfer convective coefficients. Applied Thermal Engineering. 89:587-599. https://doi.org/10.1016/j.applthermaleng.2015.06.053S5875998

External heat losses in small turbochargers: Model and experiments

[EN] The behavior of small turbochargers is deeply affected by heat transfer phenomena. The external heat losses of these machines are studied and a simplified model that takes into account both radiation and convective mechanisms has been proposed. The model has been adjusted in a turbocharger test bench for two different turbochargers, later on it has been validated against experimental measurements on an engine test bench. Finally, the model has been used to estimate the most important external heat flows among the different elements of the turbocharger, showing the operative points in which external heat transfer in turbochargers cannot be neglected. (C) 2014 Elsevier Ltd. All rights reserved.This work has been financial supported by Jaguar Land Rover Ltd.Payri González, F.; Olmeda, P.; Arnau Martínez, FJ.; Dombrovsky, A.; Smith, L. (2014). External heat losses in small turbochargers: Model and experiments. Energy. 71:534-546. https://doi.org/10.1016/j.energy.2014.04.096S5345467

Characterization of Sidr (Ziziphus spp.) Honey from Different Geographical Origins

The current investigation was conducted to assess the melissopalynological, physicochemical, and biochemical properties, antimicrobial and antioxidant activities as well as total phenolic and total flavonoid contents of 794 Sidr honey samples collected from the Saudi market that had been imported from 12 different countries. Testing Sidr honey from different countries showed different levels of growth suppression observed against five drug resistant bacterial strains. The pathogenic strains were Staphylococcus aureus, Streptococcus mutans, Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa. The antimicrobial activity showed growth suppression levels which varied according to the origin of the honey. The comparative study of Sidr honeys revealed a strong correlation between total polyphenol and flavonoid contents and significant radical scavenging activities in particular Egyptian and Saudi Arabian honeys. The melissopalynological and physicochemical properties of different Sidr honeys complied with the recommendations of the WHO Codex Alimentarius, the European Union standards for honey quality, and the Gulf Technical Regulation on honey (GSO 147:2008-Standards Store-GCC Standardization Organization). It was concluded that Sidr honey from different geographical areas has the capacity to suppress the growth of pathogenic bacteria and perform significant radical scavenging activities

Historical Building Monitoring Using an Energy-Efficient Scalable Wireless Sensor Network Architecture

We present a set of novel low power wireless sensor nodes designed for monitoring wooden masterpieces and historical buildings, in order to perform an early detection of pests. Although our previous star-based system configuration has been in operation for more than 13 years, it does not scale well for sensorization of large buildings or when deploying hundreds of nodes. In this paper we demonstrate the feasibility of a cluster-based dynamic-tree hierarchical Wireless Sensor Network (WSN) architecture where realistic assumptions of radio frequency data transmission are applied to cluster construction, and a mix of heterogeneous nodes are used to minimize economic cost of the whole system and maximize power saving of the leaf nodes. Simulation results show that the specialization of a fraction of the nodes by providing better antennas and some energy harvesting techniques can dramatically extend the life of the entire WSN and reduce the cost of the whole system. A demonstration of the proposed architecture with a new routing protocol and applied to termite pest detection has been implemented on a set of new nodes and should last for about 10 years, but it provides better scalability, reliability and deployment properties

The effect of organisational absorptive capacity on business intelligence systems efficiency and organisational efficiency

Purpose: Business intelligence (BI) systems (i.e. technology and procedures that transform raw data into useful information for managers to enable them to make better and faster decisions) have enormous potential to improve organisational efficiency. However, given the high expenditure involved in the deployment of these systems, the factors that will enable their successful integration should be thoroughly considered and assessed before these systems are adopted. Absorptive capacity (ACAP) is the ability of organisations to gather, absorb and strategically influence new external information, and as such, there is a strong theoretical connection between ACAP and BI systems. This research aims to empirically investigate the relationship between the dimensions underpinning ACAP (i.e. acquisition, assimilation, transformation and exploitation) and whether and how they affect the efficiency of BI systems, which, in turn, can enhance organisational efficiency. Design/methodology/approach: This study formulates five hypotheses addressing the effect of ACAP dimensions on BI systems efficiency and the effect of BI systems efficiency on organisational efficiency. It synthesises previous qualitative work and current research to derive sets of measures for each of the key constructs of the study. It follows a quantitative methodology, which involves the collection of survey data from senior managers in the telecommunications industry and the analysis of the data using partial least squares – structural equation modelling (PLS-SEM). Findings: The results of the analysis confirmed the validity of the constructs and proposed measures and supported all five hypotheses suggesting a strong positive relationship between the ACAP dimensions, acquisition, assimilation, transformation and exploitation and the efficiency of BI systems and a strong effect of BI systems efficiency on organisational efficiency. Practical implications: The study offers a comprehensive model of ACAP and BI systems efficiency. The set of measures that underpin these constructs could help researchers understand how ACAP dimensions are practically implemented and could contribute to their efforts to develop ACAP measurement instruments. At the same time, the model can help managers assess the readiness of their firms to adopt BI systems and identify which areas should be further developed, before committing to the substantial financial investment associated with BI systems. It also provides a set of practical solutions that could be implemented to enable a more robust ACAP and support a better integration of BI systems. Originality/value: Following an empirical approach, this study refines one’s theoretical and practical understanding of ACAP as an organisational dynamic capability and its dimensions; it provides an account on how each dimension affects different aspects of BI systems efficiency, which, in turn, may contribute to the improvement of organisational efficiency. Moreover, the study reframes ACAP measures as a set of requirements that can be practically assessed and followed before attempting to purchase BI systems

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis

Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous carcinomas from a single centre. Of 148 penile tumours, 15 (10%) were diagnosed as pure verrucous carcinomas. The expression of the cell-cycle-associated proteins p53, p21, RB, p16INK4A and Ki67 were examined by immunohistochemistry. Human papillomavirus infection was determined by polymerase chain reaction to identify a wide range of virus types. The expression of p16INK4A and Ki67 was significantly lower in verrucous carcinoma than in usual type squamous cell carcinoma, whereas the expression of p53, p21 and RB was not significantly different. p53 showed basal expression in contrast to usual type squamous cell carcinoma. Human papillomavirus infection was present in only 3 out of 13 verrucous carcinomas. Unique low-risk, high-risk and mixed viral infections were observed in each of the three cases. In conclusion, lower levels of p16INK4A and Ki67 expressions differentiate penile verrucous carcinoma from usual type squamous cell carcinoma. The low Ki67 index reflects the slow-growing nature of verrucous tumours. The low level of p16INK4A expression and human papillomavirus detection suggests that penile verrucous carcinoma pathogenesis is unrelated to human papillomavirus infection and the oncogenes and tumour suppressor genes classically altered by virus infection.Peer reviewedFinal Accepted Versio

The Bioactive Value of Tamarix gallica Honey from Different Geographical Origins

This study was conducted to assess the bioactive value of Tamarix gallica honey samples collected from three countries. In total, 150 Tamarix gallica honey samples from Saudi Arabia (50), Libya (50), and Egypt (50) were collected and compared, based on the results of the melissopalynological analysis, their physicochemical attributes, antioxidant and antimicrobial activities, and biochemical properties, together with their total phenolic and total flavonoid contents. Depending on the geographical origin, we observed different levels of growth suppression for six resistant bacterial strains. The pathogenic microorganisms tested in this study were Staphylococcus aureus, Streptococcus mutans, Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, and Pseudomonas aeruginosa. There was a strong correlation between the polyphenol and flavonoid contents, as well as significant (p < 0.05) radical scavenging activities. The melissopalynological analysis and physicochemical properties complied with the recommendation of the Gulf and Egyptian Technical Regulations on honey, as well as the Codex Alimentarius of the World Health Organization and the European Union Normative related to honey quality. It was concluded that Tamarix gallica honey from the three countries has the capacity to suppress pathogenic bacterial growth and has significant radical scavenging activities. Moreover, these findings suggest that Tamarix gallica honey may be considered as an interesting source of antimicrobial compounds and antioxidants for therapeutical and nutraceutical industries or for food manufacturers