Quantum correlations between single telecom photons and a multimode on-demand solid-state quantum memory

Quantum correlations between long-lived quantum memories and telecom photons that can propagate with low loss in optical fibers are an essential resource for the realization of large-scale quantum information networks. Significant progress has been realized in this direction with atomic and solid-state systems. Here, we demonstrate quantum correlations between a telecom photon and a multimode ondemand solid state quantum memory. This is achieved by mapping a correlated single photon onto a spin collective excitation in a Pr 3+ :Y 2 SiO 5 crystal for a controllable time. The stored single photons are generated by cavity-enhanced spontaneous parametric down-conversion and heralded by their partner photons at telecom wavelength. These results represent the first demonstration of a multimode on-demand solid state quantum memory for external quantum states of light. They provide an important resource for quantum repeaters and pave the way for the implementation of quantum information networks with distant solid state quantum nodes.We acknowledge financial support by the ERC Starting Grant QuLIMA, by the Spanish Ministry of Economy and Competitiveness (MINECO) and Fondo Europeo de Desarrollo Regional (FEDER) (FIS2015-69535-R), by MINECO Severo Ochoa through Grant No. SEV-2015-0522 and through the Ph.D. Fellowship Program (for A. S.), by AGAUR via 2014 SGR 1554, by Fundació Cellex, and by CERCA Programme/Generalitat de Catalunya

Involvement of the HLXB9 homeobox gene in Currarino syndrome [2]

published_or_final_versio

Moderation of Information Asymmetry, Self Esteem to the Effect of Participatory Budgeting on Budgetary Slack Government of South Sulawesi Province

Suspected budgetary participation is not always linear effect on budgetary slack. This is because the information asymmetry factor, and self esteem. This study aims to determine whether the asymmetry of information and self-esteem able to moderate Effect of participatory budgeting and budgetary slack. The number of samples in the study were 100 echelons SKPD South Sulawesi Provincial Government selected based on purposive sampling method. The data analysis technique used is moderation regression analysis (MRA). The results obtained are variable participatory budgeting has a positive effect on budgetary slack. Variable self esteem weaken the influence of participatory budgeting in the budgetary slack, while strengthening the influence of information asymmetry variable participatory budgeting in the budgetary slack

Procjena anthelmintičke učinkovitosti pripravaka albendazola i ivermektina u magaraca u Darfuru u Sudanu

The therapeutic efficacies of albendazole and ivermectin drench formulation at the manufacturer’s recommended dose were evaluated in a controlled trial in Nyala town, South Darfur State, Sudan. The study involved 24 donkeys naturally infected with gastrointestinal nematodes; they were divided into four groups of equal size. Albendazole was administered orally once at a dose rate of 10 mg/kg body mass, or twice, 14 days apart at dose rate of 10 mg/kg body mass. Ivermectin was administered orally as a single dose at 200 μg/kg body mass. Treatment efficacy was based on the mean faecal egg count reduction 14 days post treatment. A faecal egg count reduction of 100% was found after treatment with albendazole and ivermectin. In addition efficacy percentages of albendazole and ivermectin against immature and adult nematodes were as follows: Trichostrongylus axei 67.09% and 100%, Parascaris equorum 100% and 100%, Oxyuris equi 100% and 100%, Strongylus sp. 98.4% and 100%; and small strongyles 100% and 100%. Albendazole single and twice and ivermectin with the single dose showed moderate efficacy (33%, 59.08% and 62.71%, respectively) against larvae found in the cranial mesenteric artery aneurisms. No adverse reactions were observed in treated donkeys during the experiment period.Učinkovitost pripravaka albendazola i ivermektina u preporučenoj dozi istražena je u kontroliranom pokusu provedenom na magarcima u gradu Nyala u južnom Darfuru u Sudanu. Istraživanje je obuhvatilo 24 magarca prirodno invadirana želučanocrijevnim oblićima. Magarci su bili ravnomjerno raspoređeni u četiri skupine te peroralno liječeni albendazolom u dozi od 10 mg/kg tjelesne mase jednokratno ili dvokratno u razmaku od dva tjedna. Ivermektinom su liječeni peroralno i to jednokratno u dozi od 200 mg/kg tjelesne mase. Ljekovit učinak bio je određen na temelju smanjenja broja jaja u izmetu dva tjedna nakon liječenja. Dokazano je bilo 100%-tno smanjenje broja jaja nakon liječenja obama pripravcima. Učinkovitost je bila dokazana i postmortalnom parazitološkom pretragom i to prebrojavanjem nezrelih i odraslih oblića. U liječenih životinja ustanovljeno je 67,9% manje nezrelih te 100% manje odraslih oblića Trichostrongylus axei. Stopostotna učinkovitost bila je dokazana za nezrele i za zrele obliće Parascaris equorum, Oxyuris equi te male strongilide. Nešto manja učinkovitost (98,4%) bila je dokazana za nezrele obliće Strongylus sp. Kombinacija jednokratnoga i dvokratnoga davanja albendazola s jednokratnim davanjem ivermektina pokazala je prosječno dobru učinkovitost (33%, 59,08% i 62,71%) protiv ličinki u aneurizmama na području kranijalne mezenterijske arterije. U magaraca nisu bile primijećene nikakve nuspojave nakon primjene lijekova

Procjena anthelmintičke učinkovitosti pripravaka albendazola i ivermektina u magaraca u Darfuru u Sudanu

The therapeutic efficacies of albendazole and ivermectin drench formulation at the manufacturer’s recommended dose were evaluated in a controlled trial in Nyala town, South Darfur State, Sudan. The study involved 24 donkeys naturally infected with gastrointestinal nematodes; they were divided into four groups of equal size. Albendazole was administered orally once at a dose rate of 10 mg/kg body mass, or twice, 14 days apart at dose rate of 10 mg/kg body mass. Ivermectin was administered orally as a single dose at 200 μg/kg body mass. Treatment efficacy was based on the mean faecal egg count reduction 14 days post treatment. A faecal egg count reduction of 100% was found after treatment with albendazole and ivermectin. In addition efficacy percentages of albendazole and ivermectin against immature and adult nematodes were as follows: Trichostrongylus axei 67.09% and 100%, Parascaris equorum 100% and 100%, Oxyuris equi 100% and 100%, Strongylus sp. 98.4% and 100%; and small strongyles 100% and 100%. Albendazole single and twice and ivermectin with the single dose showed moderate efficacy (33%, 59.08% and 62.71%, respectively) against larvae found in the cranial mesenteric artery aneurisms. No adverse reactions were observed in treated donkeys during the experiment period.Učinkovitost pripravaka albendazola i ivermektina u preporučenoj dozi istražena je u kontroliranom pokusu provedenom na magarcima u gradu Nyala u južnom Darfuru u Sudanu. Istraživanje je obuhvatilo 24 magarca prirodno invadirana želučanocrijevnim oblićima. Magarci su bili ravnomjerno raspoređeni u četiri skupine te peroralno liječeni albendazolom u dozi od 10 mg/kg tjelesne mase jednokratno ili dvokratno u razmaku od dva tjedna. Ivermektinom su liječeni peroralno i to jednokratno u dozi od 200 mg/kg tjelesne mase. Ljekovit učinak bio je određen na temelju smanjenja broja jaja u izmetu dva tjedna nakon liječenja. Dokazano je bilo 100%-tno smanjenje broja jaja nakon liječenja obama pripravcima. Učinkovitost je bila dokazana i postmortalnom parazitološkom pretragom i to prebrojavanjem nezrelih i odraslih oblića. U liječenih životinja ustanovljeno je 67,9% manje nezrelih te 100% manje odraslih oblića Trichostrongylus axei. Stopostotna učinkovitost bila je dokazana za nezrele i za zrele obliće Parascaris equorum, Oxyuris equi te male strongilide. Nešto manja učinkovitost (98,4%) bila je dokazana za nezrele obliće Strongylus sp. Kombinacija jednokratnoga i dvokratnoga davanja albendazola s jednokratnim davanjem ivermektina pokazala je prosječno dobru učinkovitost (33%, 59,08% i 62,71%) protiv ličinki u aneurizmama na području kranijalne mezenterijske arterije. U magaraca nisu bile primijećene nikakve nuspojave nakon primjene lijekova

Recurrence and higher ergodic properties for quenched random Lorentz tubes in dimension bigger than two

We consider the billiard dynamics in a non-compact set of R^d that is constructed as a bi-infinite chain of translated copies of the same d-dimensional polytope. A random configuration of semi-dispersing scatterers is placed in each copy. The ensemble of dynamical systems thus defined, one for each global realization of the scatterers, is called `quenched random Lorentz tube'. Under some fairly general conditions, we prove that every system in the ensemble is hyperbolic and almost every system is recurrent, ergodic, and enjoys some higher chaotic properties.Comment: Final version for J. Stat. Phys., 18 pages, 4 figure

Can we (control) Engineer the degree learning process?

This paper investigates how control theory could be applied to learning processes in engineering education. The initial point for the analysis is White’s Double Loop learning model of human automation control modified for the education process where a set of governing principals is chosen, probably by the course designer. After initial training the student decides unknowingly on a mental map or model. After observing how the real world is behaving, a strategy to achieve the governing variables is chosen and a set of actions chosen. This may not be a conscious operation, it maybe completely instinctive. These actions will cause some consequences but not until a certain time delay. The current model is compared with the work of Hollenbeck on goal setting, Nelson’s model of self-regulation and that of Abdulwahed, Nagy and Blanchard at Loughborough who investigated control methods applied to the learning process

Epilepsy with auditory features: A heterogeneous clinico-molecular disease

Objective: To identify novel genes implicated in epilepsy with auditory features (EAF) in phenotypically heterogeneous families with unknown molecular basis. Methods: We identified 15 probands with EAF in whom an LGI1 mutation had been excluded. We performed electroclinical phenotyping on all probands and available affected relatives. We used whole-exome sequencing (WES) in 20 individuals with EAF (including all the probands and 5 relatives) to identify single nucleotide variants, small insertions/deletions, and copy number variants. Results: WES revealed likely pathogenic variants in genes that had not been previously associated with EAF: a CNTNAP2 intragenic deletion, 2 truncating mutations of DEPDC5, and a missense SCN1A change. Conclusions: EAF is a clinically and molecularly heterogeneous disease. The association of EAF with CNTNAP2, DEPDC5, and SCN1A mutations widens the phenotypic spectrum related to these genes. CNTNAP2 encodes CASPR2, a member of the voltage-gated potassium channel complex in which LGI1 plays a role. The finding of a CNTNAP2 deletion emphasizes the importance of this complex in EAF and shows biological convergence

Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33.

Nonsyndromic defects in the urinary tract are the most common cause of end-stage renal failure in children and account for a significant proportion of adult nephropathy. The genetic basis of these disorders is not fully understood. We studied seven multiplex kindreds ascertained via an index case with a nonsyndromic solitary kidney or renal hypodysplasia. Systematic ultrasonographic screening revealed that many family members harbor malformations, such as solitary kidneys, hypodysplasia, or ureteric abnormalities (in a total of 29 affected individuals). A genomewide scan identified significant linkage to a 6.9-Mb segment on chromosome 1p32-33 under an autosomal dominant model with reduced penetrance (peak LOD score 3.5 at D1S2652 in the largest kindred). Altogether, three of the seven families showed positive LOD scores at this interval, demonstrating heterogeneity of the trait (peak HLOD 3.9, with 45% of families linked). The chromosome 1p32-33 interval contains 52 transcription units, and at least 23 of these are expressed at stage E12.5 in the murine ureteric bud and/or metanephric mesenchyme. These data show that autosomal dominant nonsyndromic renal hypodysplasia and associated urinary tract malformations are genetically heterogeneous and identify a locus for this common cause of human kidney failure