Choanal polyp originating from superior turbinate

Solitary, benign soft tissue masses starting at the nasal cavity and extending to the nasopharynx are termed choanal polyps. They most frequently originate in the maxillary sinus and are termed antra-choanal polyp. Cases of CP originating in the upper concha are rather rare and only one case has been reported in literature in the English language to the best of our knowledge. This paper discusses a CP case originating in the upper concha, which was treated by endoscopic surgical technique, in the light of its clinical presentation and radiological findings.

Closure of tympanic membrane perforations using repeated trichloracetic acid

Our aim in this study is to show the efficacy of trichloracetic acid cauterization in the tympanic membrane perforations. Between January 2002 and January 2012 central perforations in 160 ears of 142 cases were tried to be closed by repeated trichloracetic acid cauterization in one week interval followed by the placement of a piece of cigarette paper to the perforation site. In 98 of 137 ears (71.5 %) that followed-up for a desired period of time, perforation was closed after an average of 4.2 applications. No statistical relation was found between the success of treatment, and the age of patient, the site of perforation and previous history of otorrhea. It was shown that the width of perforation is an important factor in the success of treatment. [Med-Science 2016; 5(2.000): 544-6

Considering the effect of Stapes Footplate's macroscopic vision on surgical complication rate

*Çayır, Serkan ( Aksaray, Yazar )Objective: To determine the effect of stapes footplates color on the intraoperative complications and outcomes of otosclerosis surgery Design: Retrospective study Setting: Ankara Numune Hospital database records between 2008 and 2011 Subjects: Eighty-six patients who underwent otosclerosis surgery between 2008 and 2011 (38 male and 48 female) were conducted to the study. Intervention: Patients were classified into three groups according to the stapes footplates macroscopic view before stapedectomy application as blue (67%), white (21%) and obliterative (12%). Main outcome measures: Among the groups, demographical variables, preoperative and postoperative air-bone gap, gain scores and intraoperative complications were investigated. Results: In the white otosclerosis group, female gender (P=.013) and bilaterality (P=.032) rates were higher than the blue otosclerosis group. The air-bone gap closure was 22 dB in white otosclerosis, 15 dB in blue otosclerosis and 16 dB in obliterative otosclerosis. The groups were evaluated in terms of the footplate complications that occur during the operation. It was estimated that 44.2% of footplate complications were seen in white otosclerosis, while this percentage was 3.4% in blue otosclerosis. No footplate complications were found in obliterative otosclerosis. Conclusion: The intraoperative macroscopic evaluation of the color changes of stapes footplate was found to be significant in terms of intraoperative complications. Related with this, to decrease intraoperative complication rate, well-experienced surgeons should evaluate the stapes footplate color before stapedectomy procedure and beginner surgeons should gain experience in cases of blue otosclerosis

Comparison of the relationship between body mass index and apnea hypnoea index in different age groups in obstructive sleep apnea syndrome patients

13. Uluslararası Kulak Burun Boğaz ve Baş Boyun Cerrahisi Kongresi’nde (5-7 Nisan 2018, Ankara) sözlü bildiri olarak sunulmuştur.Obezite tıkayıcı uyku apne sendromu (TUAS) için iyi tanımlanmış bir risk faktörüdür, ancak obezitenin TUAS gelişim riski üzerine etkileri, farklı yaş gruplarında farklı bulunmuştur. Bu çalışma ile farklı yaş gruplarında, vücut kitle indeksi (VKİ) ile apne hipopne indeksi (AHİ) arasındaki ilişkinin araştırılması ve obezitenin TUAS ağırlığı üzerine etkilerinin yaş grupları arasındaki farkının araştırılması amaçlandı. TUAS ön tanısı ile tüm gece polisomnografisi yapılan hastaların polisomnografik kayıtları retrospektif olarak incelendi. Çalışmaya dahil edilme kriterlerini karşılayan 236 hasta, yaş aralıklarına göre 4 farklı gruba ayrıldı. Grupları sırası ile 40 yaş altı, 41-50 yaş arası, 51-60 yaş arası ve 60 yaş üstü hastalar oluşturdu. Tüm hastaların ve her bir grubun VKİ ve AHİ’leri arasındaki korelasyon araştırıldı. Altmış yaş üstü hasta grubu haricindeki tüm gruplarda VKİ ile AHİ arasında istatistiki anlamlı aynı yönlü korelasyon saptandı. Literatürle uyumlu olarak ileri yaş grubunda obezitenin TUAS şiddeti üzerine etkisi, diğer yaş gruplarına göre daha düşük olduğu sonucuna ulaşıldı.Obesity is a well-defined risk factor for obstructive sleep apnea syndrome (OSAS), but the effects of obesity on OSAS development risk are different in different age groups. The aim of this study was to investigate the relationship between body mass index (BMI) and apnea hypopnea index (AHI) in different age groups and to investigate the effect of obesity on OSAS severity among age groups. Polysomnographic records of patients who underwent whole night polysomnography with OSAS pre-diagnosis were retrospectively reviewed. Two hundred thirty-six patients who met the inclusion criteria were divided into 4 groups according to their age range. The groups were composed of patients under the age of 40, between the ages of 41-50, between the ages of 51-60 and over 60. Correlations between BMI and AHI of all patients and each group were investigated. There was a statistically significant correlation between BMI and AHI in all groups except patients over 60 years of age. .In accordance with the literature, the effect of obesity on OSAS severity in the elderly group was found to be lower than in the other age groups

Evaluation Of Autoinflammatory Disease Genes In Nasal Polyposis

Background/aim: To investigate cold-induced autoinflammatory syndrome 1 (CIAS1) gene polymorphisms that cause autoinflammatory diseases in patients with nasal polyposis (NP). Materials and methods: The study included 30 patients diagnosed with NP and 30 healthy age-matched individuals as a control group. CIAS1 polymorphisms were assessed by DNA sequence analysis. Patients with nasal polyps and the control group were compared in terms of gene polymorphisms. Each of the 8 polymorphisms of the CIAS1 gene was analyzed separately in the patient group. Results: The most frequently observed polymorphisms in the patient group were c.732G > A in 83%, c.663C > T in 23%, and c.1308C > A in 23% of the patients. c.732G > A polymorphism was evaluated separately. Guanine was transformed to adenine at the 732nd nucleotide position of the CIAS1 gene in the cDNA of chromosome 1. Conclusion: The CIAS1 gene c.732G > A polymorphism was thought to be responsible for an increase in disease susceptibility. The frequency of the "A" allele is higher in the patient group compared to the control group. Autoinflammatory diseases seem like a candidate to be one of these factors. This is the first report to define the role of autoinflammatory diseases among these factors.WoSScopu

Analysis of Lower Airway Inflammation in a Rabbit Model of Acute Rhinosinusitis

This study aimed to investigate the association of inflammatory changes of upper and lower airways in a rabbit model of acute rhinosinusitis. The study included six adult albino rabbits. The sinuses of one animal were injected with saline solution and the animal was served as sham control. Other animals were implanted with intranasal S. aureus soaked-absorbable gelatin sponge. Acute rhinosinusitis was induced and subjects were sacrificed at the end of the second week. Tissue samples from all levels of the airway were obtained. They were evaluated for the presence of inflammatory changes histologically. A scoring system for airway inflammation was used for quantitative assessment of the degree of inflammation. Structural changes in the epithelial and stromal layers of the upper and lower airway structures were analyzed, as well. The animal of which the sinuses were injected with saline solution developed neither acute rhinosinusitis nor lower airway inflammation. In contrast, the animals in which acute rhinosinusitis was induced demonstrated significant upper and lower airway inflammation histologically. Inflammatory changes ranged from engorgement of blood vessels and polymorphonuclear cell proliferation within the capillaries, in the perivascular tissue of the epithelium or in the lamina propria and to epithelial disruption. Nasal airway inflammation scores (2.86 ± 1.81) were significantly higher than lower airway scores (1.36 ± 0.77), (P < 0.01). We obtained a generalized mucosal inflammatory response against localized bacterial inflammation in a rabbit model of acute rhinosinusitis, confirming the suggestion of ‘one airway––one disease’ from a bacterial infection point of view