1,194 research outputs found

    Strength functions, entropies and duality in weakly to strongly interacting fermionic systems

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    We revisit statistical wavefunction properties of finite systems of interacting fermions in the light of strength functions and their participation ratio and information entropy. For weakly interacting fermions in a mean-field with random two-body interactions of increasing strength λ\lambda, the strength functions Fk(E)F_k(E) are well known to change, in the regime where level fluctuations follow Wigner's surmise, from Breit-Wigner to Gaussian form. We propose an ansatz for the function describing this transition which we use to investigate the participation ratio ξ2\xi_2 and the information entropy SinfoS^{\rm info} during this crossover, thereby extending the known behavior valid in the Gaussian domain into much of the Breit-Wigner domain. Our method also allows us to derive the scaling law for the duality point λ=λd\lambda = \lambda_d, where Fk(E)F_k(E), ξ2\xi_2 and SinfoS^{\rm info} in both the weak (λ=0\lambda=0) and strong mixing (λ=\lambda = \infty) basis coincide as λd1/m\lambda_d \sim 1/\sqrt{m}, where mm is the number of fermions. As an application, the ansatz function for strength functions is used in describing the Breit-Wigner to Gaussian transition seen in neutral atoms CeI to SmI with valence electrons changing from 4 to 8

    Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs

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    SummaryObjectiveThe induction of synovial tissue to the meniscal lesion is crucial for meniscal healing. Synovial Mesenchymal stem cells (MSCs) are an attractive cell source because of their high proliferative and chondrogenic potentials. We examined whether transplantation of synovial MSCs promoted healing after meniscal repair of extended longitudinal tear of avascular area in a microminipig model.DesignLongitudinal tear lesion was made in medial menisci and sutured in both knees, and then a synovial MSC suspension was administered for 10 min only in unilateral knee. The sutured meniscus was evaluated morphologically and biomechanically at 2, 4, and 12 weeks. The behavior of transplanted MSCs was also examined.ResultsThe meniscal healing at 12 weeks was significantly better in the MSC group than in the control group; macroscopically, histologically and by T1rho mapping analysis. Transmission electron microscopic analysis demonstrated that the meniscus lesion was occupied by dense collagen fibrils only in the MSC group. Biomechanical analysis revealed that the tensile strength to failure of the meniscus higher in the MSC group than in the control group in each microminipig. Synovial tissue covered better along the superficial layer from the outer zone into the lesion of the meniscus in the MSC group at 2 and 4 weeks in each microminipig. Synovial MSCs labeled with ferucarbotran were detected in the meniscus lesion and adjacent synovium by MRI at 2 weeks.ConclusionTransplantation of synovial MSCs promoted healing after meniscal repair with induction of synovium into the longitudinal tear in the avascular zone of meniscus in pigs

    Monoiodoacetic acid induces arthritis and synovitis in rats in a dose- and time-dependent manner: proposed model-specific scoring systems

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    SummaryObjectiveIn a rat monoiodoacetic acid (MIA)-induced arthritis model, the amount of MIA commonly used was too high, resulting in rapid bone destruction. We examined the effect of MIA concentrations on articular cartilage and infrapatellar fat pad (IFP). We also established an original system for “macroscopic cartilage and bone score” and “IFP inflammation score” specific to the rat MIA-induced arthritis model.DesignMale Wistar rats received a single intra-articular injection of MIA in the knee. The amount of MIA was 0.1, 0.2, 0.5, and 1 mg respectively. Articular cartilage was evaluated at 2–12 weeks. IFP was also observed at 3–14 days.ResultsMacroscopically, low MIA doses induced punctate depressions on the cartilage surface, and cartilage erosion proceeded slowly over 12 weeks, while higher MIA doses already induced cartilage erosion at 2 weeks, followed by bone destruction. MIA macroscopic cartilage and bone score, OARSI histological score, and Mankin score increased in a dose- and time-dependent manner. The IFP inflammation score peaked at 5 days in low dose groups, then decreased, while in high dose groups, the IFP score continued to increase over 14 days due to IFP fibrosis.ConclusionsPunctate depressions, cartilage erosion, and bone destruction were observed in the MIA-induced arthritis model. The macroscopic cartilage and bone scoring enabled the quantification of cartilage degeneration and demonstrated that MIA-induced arthritis progressed in a dose- and time-dependent manner. IFP inflammation scores revealed that 0.2 mg MIA induced reversible synovitis, while 1 mg MIA induced fibrosis of the IFP body

    Porosities of Protoplanetary Dust Agglomerates from Collision Experiments

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    Aggregation of dust through sticking collisions is the first step of planet formation. Basic physical properties of the evolving dust aggregates strongly depend on the porosity of the aggregates, e.g. mechanical strength, thermal conductivity, gas-grain coupling time. Also the outcome of further collisions depends on the porosity of the colliding aggregates. In laboratory experiments we study the growth of large aggregates of \sim 3 mm to 3 cm through continuous impacts of small dust agglomerates of 100 μ\mum size, consisting of μ\mum grains at different impact velocities. The experiments show that agglomerates grow by direct sticking as well as gravitational reaccretion. The latter can be regarded as suitable analog to reaccretion of fragments by gas drag in protoplanetary disks. Experiments were carried out in the velocity range between 1.5 m/s and 7 m/s. With increasing impact velocities the volume filling factor of the resulting agglomerates increases from ϕ=0.2\phi = 0.2 for 1.5 m/s to ϕ=0.32\phi = 0.32 for 7 m/s. These values are independent of the target size. Extrapolation of the measured velocity dependence of the volume filling factor implies that higher collision velocities will not lead to more compact aggregates. Therefore, ϕ=0.32\phi = 0.32 marks a degree of compaction suitable to describe structures forming at v>6m/s\rm v > 6\, m/s. At small collision velocities below 1 m/s highly porous structures with ϕ0.10\phi \approx 0.10 will form. For intermediate collision velocities porosities vary. Depending on the disk model and resulting relative velocities, objects in protoplanetary disks up to dm-size might evolve from highly porous (ϕ0.10\phi \approx 0.10) to compact (ϕ=0.32\phi = 0.32) with a more complex intermediate size range of varying porosity.Comment: Accepted by The Astrophysical Journa

    Solar neutrino-electron scattering as background limitation for double beta decay

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    The background on double beta decay searches due to elastic electron scattering of solar neutrinos of all double beta emitters with Q-value larger than 2 MeV is calculated, taking into account survival probability and flux uncertainties of solar neutrinos. This work determines the background level to be [1-2]E-7 counts /keV/kg/yr, depending on the precise Q-value of the double beta emitter. It is also shown that the background level increases dramatically if going to lower Q-values. Furthermore, studies are done for various detector systems under consideration for next generation experiments. It was found that experiments based on loaded liquid scintillator have to expect a higher background. Within the given nuclear matrix element uncertainties any approach exploring the normal hierarchy has to face this irreducible background, which is a limitation on the minimal achievable background for purely calorimetric approaches. Large scale liquid scintillator experiments might encounter this problem already while exploring the inverted hierarchy. Potential caveats by using more sophisticated experimental setups are also discussed

    Measuring Name System Health

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    Modern critical infrastructure assets are exposed to security threats arising from their use of IP networks and the Domain Name System (DNS). This paper focuses on the health of DNS. Indeed, due to the increased reliance on the Internet, the degradation of DNS could have significant consequences for the critical infrastructure. This paper describes the Measuring Naming System (MeNSa), a framework designed to provide a formal methodology, metrics and tools for evaluating DNS health. Additionally, it proposes a process for aggregating health and security metrics to provide potential threat indicators. Results from a scenario-based experiment demonstrate the utility of the framework and aggregation metrics
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