Effects of chicory roots on finishing performance and CLA and fatty acid composition in longissimus muscle of Friesian steers

Low profitability is believed to be the greatest hindrance profitability is believed to be the greatest hindrance for a more extensive use of dairy breed bull calves in for a more extensive use of dairy breed bull calves in organic beef production systems organic beef production systems Among certain consumers, there is an increasing interest Among certain consumers, there is an increasing interest for organic beef production for organic beef production However, there is a need for reliable information about However, there is a need for reliable information about and documentation for production parameters, methods and documentation for production parameters, methods for rearing and housing, feeding strategies etc. to be able for rearing and housing, feeding strategies etc. to be able to increase the consumption of beef meat based on dairy to increase the consumption of beef meat based on dairy calves in Denmark calves in Denmark. Specifically, we believe there will be increased focus on Specifically, we believe there will be increased focus on improving animal health and welfare and product quality in improving animal health and welfare and product quality in the steer production systems the steer production systems There will also be a wish from the society and EU to use There will also be a wish from the society and EU to use and preserve the biodiversity of the marginal grazing and preserve the biodiversity of the marginal grazing areas areas The project reported here arises from a larger project The project reported here arises from a larger project investigating the effects of grazing system (set investigating the effects of grazing system (set stocking vs. two stocking vs. two-paddock rotation) for steers and the paddock rotation) for steers and the use of bioactive crops (especially chicory) use of bioactive crops (especially chicory). Chicory is used because of the possible positive Chicory is used because of the possible positive influence on animal health, i.e., parasite control, meat influence on animal health, i.e., parasite control, meat quality and sensory quality of meat from both steers quality and sensory quality of meat from both steers and pigs (including CLA content, selenium and and pigs (including CLA content, selenium and antioxidative antioxidative status, drip loss and boar status, drip loss and boar taint/ taint/androstenone androstenone levels) levels). The overall objective of the entire project was to The overall objective of the entire project was to develop production methods/strategies that could develop production methods/strategies that could improve the quality aspects of organic meat improve the quality aspects of organic meat

Effects of putrescine, cadaverine, spermine, spermidine and β-phenylethylamine on cultured bovine mammary epithelial cells

A bovine mammary epithelial cell line (BME-UV1) and three-dimensional collagen primary bovine organoids were used to evaluate the effects of cadaverine, putrescine, spermine, spermidine and β-phenylethylamine on mammary epithelial cells. Each biogenic amine was diluted in several concentrations (0-50 mM in BME-UV1 and 0-4 mM in primary bovine organoids) in the appropriate saline solution for the cell culture considered. In order to determine the activity of each compound tritiated thymidine incorporation was used. At low concentrations, all amines induced cell proliferation in both cultures. In BME-UV1, spermine significantly inhibited cell proliferation (P<0.001), while the other amines inhibited at higher concentrations (50mM). In primary bovine organoids, β−phenylethylamine significantly (P<0.001) inhibited cell proliferation at 4 mM. Organoids cultured in the presence of all amines, except β-phenylethylamine, had stellate projections indicating intense cell proliferation. Proliferation of mammary epithelial cells was stimulated at low concentrations, while at high concentrations it was inhibited. Our results suggested that the effects of each compound on mammary epithelial cells could be related to the compound itself and not to mediating by the bovine amino oxidase, responsible of the formation of toxic metabolites

Scientific Opinion on the safety and efficacy of Urea for ruminants

Urea supplementation to feed for ruminants provides non-protein nitrogen for microbial protein synthesis in the rumen and thus in part replaces other dietary protein sources. Urea supplementation of feed for ruminants at doses up to 1 % of complete feed DM (corresponding to 0.3 g/kg bw/day) is considered safe when given to animals with a well adapted ruminal microbiota and fed diets rich in easily digestible carbohydrates. Based on the metabolic fate of urea in ruminants, the use of urea in ruminant nutrition does not raise any concern for consumers\u2019 safety. Urea is considered to be non irritant to skin and eyes and its topical use suggests that it is not a dermal sensitiser. The risk of exposure by inhalation would be low. The substitution of protein by urea in well balanced feed for ruminants would not result in an increased environmental nitrogen load. Urea is an effective source of non-protein nitrogen substituting for dietary protein in ruminants

Diverse and Active Roles for Adipocytes During Mammary Gland Growth and Function

The mammary gland is unique in its requirement to develop in close association with a depot of adipose tissue that is commonly referred to as the mammary fat pad. As discussed throughout this issue, the mammary fat pad represents a complex stromal microenvironment that includes a variety of cell types. In this article we focus on adipocytes as local regulators of epithelial cell growth and their function during lactation. Several important considerations arise from such a discussion. There is a clear and close interrelationship between different stromal tissue types within the mammary fat pad and its adipocytes. Furthermore, these relationships are both stage- and species-dependent, although many questions remain unanswered regarding their roles in these different states. Several lines of evidence also suggest that adipocytes within the mammary fat pad may function differently from those in other fat depots. Finally, past and future technologies present a variety of opportunities to model these complexities in order to more precisely delineate the many potential functions of adipocytes within the mammary glands. A thorough understanding of the role for this cell type in the mammary glands could present numerous opportunities to modify both breast cancer risk and lactation performance