5 research outputs found
(3R*,4R*)-1-(4-Chlorophenyl)-4-[2-hydroxy-3-(morpholinomethyl)phenyl]-3-phenoxyazetidin-2-one
The β-lactam ring of the title compound, C26H25ClN2O4, is nearly planar (r.m.s. deviation = 0.025 Å) and the morpholine ring adopts a chair conformation. The mean plane of the β-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)° with the two benzene rings and the phenyl ring, respectively. The conformation of the title compound is stabilized by intramolecular C—H⋯O and O—H⋯N interactions. The crystal structure features C—H⋯π and aromatic π–π stacking interactions [centroid–centroid distances = 3.684 (4) and 3.883 (4) Å]
3-(2,4-Dichlorophenoxy)-1-(4-methoxyphenyl)-4-(3-nitrophenyl)azetidin-2-one
In the title compound, C22H16Cl2N2O5, the nearly planar four-membered β-lactam ring [maximum deviations of 0.011 (2) for the N atom] makes dihedral angles of 68.34 (13), 83.04 (13) and 3.37 (13)° with the dichloro-, nitro- and methoxyphenyl rings, respectively. The crystal structure is stabilized by C—H⋯O hydrogen-bond interactions. In addition, a π–π stacking interaction [centroid–centroid distance = 3.6622 (12) Å] is observed between the β-lactam and nitrophenyl rings
2-[(E)-(4-Methylphenyl)iminomethyl]-6-(morpholin-4-ylmethyl)phenol
In the title compound, C19H22N2O2, the morpholine ring adopts an almost perfect normal chair conformation with puckering parameters Q
T, θ and ϕ of 0.5642 (18) Å, 177.32 (17) and ϕ = 10 (4)°, respectively. The two benzene rings make a dihedral angle of 42.67 (8)° with each other. An intramolecular O—H⋯N hydrogen bond helps to stabilize the molecular conformation. Aromatic C—H⋯π interactions and π–π stacking interactions [centroid–centroid distance = 3.6155 (15) Å] between the benzene rings contribute to the stabilization of the crystal structure
3-(4-Chlorophenoxy)-1-(4-methoxyphenyl)-4-(4-nitrophenyl)azetidin-2-one
In the title compound, C22H17ClN2O5, the nearly planar four-membered beta-lactam ring [maximum deviation of 0.016 (1) for the N atom] makes dihedral angles of 53.07 (9), 73.19 (9) and 6.61 (9)degrees with the chloro-, nitro- and methoxybenzene rings, respectively. The crystal structure is stabilized by C-H center dot center dot center dot O hydrogen bonds, a weak C-H center dot center dot center dot pi interaction and a pi-pi stacking interaction [centroid-centroid distance = 3.6513 (8) angstrom] between the methoxybenzene rings of inversion-related molecules