15 research outputs found

    Bullet Embolism of Pulmonary Artery: A Rare Case

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    Bullet embolism of pulmonary artery is a vascular traumatic entity that is a very rare but with serious complications. The bullet can lead to vascular embolism by entering directly into the intravascular area or by migration. In pulmonary artery bullet embolism, complications with high mortality such as thrombosis, sepsis, endocarditis, cerebral stroke may be encountered. Observation and follow-up are sufficient in asymptomatic venous bullet embolism cases. In this case report, we aimed to share our experience with a patient who developed a bullet embolism of pulmonary artery as a result of gunshot injury from the right iliac region

    Revised Urinary Incontinence Scale’in Türkçe Geçerlilik ve Güvenilirlik Çalışması

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    Amaç: Bu çalışmanın amacı, Revised Urinary Incontinence Scale’in (RUIS) Türkçe geçerliliğini ve güvenilirliğini sağlamaktır. Gereç ve Yöntem: Ölçek, İngilizceden Türkçeye üç akademisyen tarafından çevrildi. Çeviri metinleri, birleştirilerek ölçeğin ilk Türkçe versiyonu oluşturuldu. Bu versiyon, ölçeğin orijinal dili olan İngilizceye tekrar çevrilerek dil uyumu incelendi. Ölçeğin kapsam geçerliliği, Davis yöntemi ile irdelendi. Madde kapsam geçerlilik indeksleri (KGİ) 0,78-1 aralığında, ölçek KGİ ise 0,89 olarak belirlendi. Yaş ortalaması 59,2±14 yıl olan 56 gönüllüye (%83,9 kadın, %16,1 erkek) RUIS, International Consultation on Incontinence Questionnaire Short Form ve Urogenital Distress Inventory’nin Türkçe versiyonları uygulandı. Bulgular: Cronbach alfa katsayısı 0,810 olarak hesaplandı. Ölçekte taban ve tavan etkisi oluşmadı. Ölçeğin Kaiser-Meyer-Olkin değeri 0,762, Bartlett küresellik testi ki-kare değeri 94,583, p değeri 0,0001 ve ‘anti-image’ korelasyon değerleri 0,709-0,884 aralığındaydı. Tek alt boyutlu yapısını koruyan ölçeğin açıklanan varyans oranı %57,943 ve öz değeri 2,897 olarak hesaplandı. Ölçeğin Türkçe versiyonunun, diğer iki ölçüm aracı ile mükemmel düzeyde (r?0,80; p?0,05) uyum gösterdiği tespit edildi. Ölçeğin doğrulayıcı faktör analizlerinde de model uyum iyiliği değerlerini karşıladığı görüldü. Sonuç: RUIS’in Türkçeye uyarlandığı, geçerliliğinin, güvenilirliğinin sağlandığı görüldü ve araştırmacıların kullanımına sunuldu

    The 33-year Retrospective Analysis of Esophageal Carcinomas: Cerrahpaşa Experience

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    Aim:Esophageal cancer is a fatal disease where the majority of patients are diagnosed at an advanced stage. In this study, we aimed to present the demographic and clinicopathological characteristics of patients who were operated for esophageal cancer.Materials and Methods:A total of 847 patients who underwent surgery, chemoradiotherapy, or palliative procedures for esophageal pathology between the years of 1985 and 2018 were retrospectively analyzed. Age, gender, tumor location, histopathology, surgical technique, and chemoradiotherapy history of patients were analyzed.Results:In the study, 488 patients were male (60.5%) and 319 were female (39.5%). The ratio of males and females was 1.52. The average age was 58.6 years, and 80.1% were older than 50 years. The most common pathological material obtained was squamous cell carcinoma (67.5%), followed by adenocarcinoma (27.7%). Total esophagectomy was performed in 435 patients; distal esophagectomy was performed in 38 patients. Transhiatal esophagectomy (n=271, 62.2%) was the most common procedure that was performed.Conclusion:Esophagectomy is the primary treatment modality for esophageal cancers. When determining the optimal treatment, appropriate patient selection, staging, and risk assessment should be made. Patient-specific treatment should be planned with a multidisciplinary approach

    One of the rare reason of abdominal pain: abdominal wall endometriosis

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    Objective: Endometriosis is defined as the presence of normal endometrial mucosa abnormally implanted in locations other than the uterine cavity. It is most commonly located in the pelvis but it is also rarely observed in the gastrointestinal tract, lung, liver, kidneys, central nervous system and abdominal wall. Abdominal wall endometriosis (AWE) commonly occurs following a caesarean section or pelvic surgery. The patients consult the physician mostly with complaints of cyclic abdominal pain and a palpable mass in the abdomen. The basic methods in diagnosing AWE are anamnesis and physical examination but ultrasound, computerized tomography, and sometimes magnetic resonance imaging of the abdomen are also used

    Renal Vascular and Ureteral Anatomic Variations in 1859 Potential Living Renal Donors

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    Background. Renal vascular and ureteral anomalies detected by preoperative computed tomography angiography (CTA) are important for determining the side of the donor nephrec-tomy and the optimal surgical technique. In the present study, we aimed to examine the renal vas-cular and ureteral variations in living kidney donor candidates

    The Association Between Trace Elements and Osmolality in Plasma and Aqueous Humor Fluid in Diabetic Rabbits

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    Trace element metabolism plays an important role in the formation of diabetes and complications of diabetes. Although trace elements changes in lenses in diabetic cataract and glaucoma formation have been investigated, there were few studies evaluating trace elements levels in plasma and aqueous humor fluid in diabetic and non-diabetic conditions. Therefore, we aimed to investigate zinc (Zn), copper (Cu), and chromium (Cr) levels in plasma and aqueous humor fluids of rabbits in the diabetic rabbit model. New Zealand male rabbits were divided into two groups as control (n = 8), and diabetes (n = 8) induced by alloxane. At the end of the experimental period, the osmolality in blood, plasma, and aqueous humor fluids from rabbits were measured by osmometer and Zn, Cu, and Cr levels in plasma and aqueous humor fluid were measured by inductively coupled plasma-optical emission spectrophotometer (ICP-OES). The osmolality in blood, plasma, and aqueous humor fluid of the diabetic group was significantly increased compared to the control group (respectively p < 0.01, p < 0.001, p < 0.001). It was analyzed that plasma Zn and Cu levels of diabetic rabbits increased significantly (respectively, p < 0.01; p < 0.001), whereas Cr level significantly decreased according to the control group (p < 0.01). It was observed that Cr and Zn levels in aqueous humor fluid in diabetes group decreased (respectively p < 0.001 and p < 0.01), and a significantly increased in Cu level (p < 0.001) compared to the control group. Related with these changes that may occur in the eye due to the measured parameters, we consider that comparative studies of these types of diabetic animal models would be useful in the evaluation of diabetes and its complications

    Crystal Structure and Thermal Decomposition of Square Planar Ni (II) Complexes with ONS Type Ligands (vol 40, pg 788, 2010)

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    durmus, sefa/0000-0001-6974-513XWOS: 000285973600018

    Investigation of Aryl Hydrocarbon Receptor, Zinc, and Vitamin B12 Levels in Chronic Gastritis with Helicobacter pylori Infection

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    Helicobacter pylori (H. pylori) infection is known as the most common cause of worldwide common chronic gastritis. Pathogenic mechanisms caused by H. pylori in diseases are still not fully understood. In addition, it has been reported that H. pylori can alter gene expressions in infected tissues and affect transcription factor activation. It is reported that aryl hydrocarbon receptor (AhR), which is a cytoplasmic transcription factor, functions in the immune system and plays a role in immune cells in barrier organs such as the gastrointestinal system, skin, and lungs. H. pylori infection affects the absorption of micronutrients such as trace elements, minerals, and vitamins by disrupting gastric secretion and acidification functions. Zinc (Zn) trace element is thought to be able to modulate the induction of AhR-responsive genes in endothelial cells. Although it is emphasized that trace elements are related with gastritis, relationship between Zn and AhR is not fully known, especially in chronic gastritis accompanied by H. pylori infection. In this study, serum levels of AhR, Zn, and AhR antagonist vitamin B12 were determined in chronic gastritis with H. pylori infection. Fifty volunteers diagnosed with H. pylori positive and negative chronic gastritis were included in this study. Collected from individuals participating were 5 ml of venous blood samples, and their serums were separated. AhR serum level of the study group was determined using enzyme-linked immunosorbent assay method. Zn concentrations in serum samples were measured using inductively coupled plasma atomic emission spectroscopy. When AhR and Zn serum levels were compared in H. pylori positive and negative chronic gastritis patients, it was found that AhR serum level of H. pylori positive chronic gastritis patients increased but it was not statistically significant (p = 0.595). However it was determined Zn and B12 serum levels were statistically significantly decreased (p < 0.001). This study has a crucial importance since to be the first one investigating relationship between serum AhR, Zn, and vitamin B12 levels in the pathogenesis of H. pylori gastritis in adults. Examination of AhR, Zn and B12 levels in H. pylori positive gastritis patients contributes to elucidating molecular mechanism of the disease
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