274 research outputs found
Polarons in semiconductor quantum-dots and their role in the quantum kinetics of carrier relaxation
While time-dependent perturbation theory shows inefficient carrier-phonon
scattering in semiconductor quantum dots, we demonstrate that a quantum kinetic
description of carrier-phonon interaction predicts fast carrier capture and
relaxation. The considered processes do not fulfill energy conservation in
terms of free-carrier energies because polar coupling of localized quantum-dot
states strongly modifies this picture.Comment: 6 pages, 6 figures, accepted for publication in Phys.Rev.
Influence of carrier-carrier and carrier-phonon correlations on optical absorption and gain in quantum-dot systems
A microscopic theory is used to study the optical properties of semiconductor
quantum dots. The dephasing of a coherent excitation and line-shifts of the
interband transitions due to carrier-carrier Coulomb interaction and
carrier-phonon interaction are determined from a quantum kinetic treatment of
correlation processes. We investigate the density dependence of both mechanisms
and clarify the importance of various dephasing channels involving the
localized and delocalized states of the system.Comment: 12 pages, 10 figure
Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens
Trypanosome infection of mammalian hosts leads, within days, to a strong early response against a small, distinct number of parasite proteins. One of these proteins is the variable surface glycoprotein (VSG). Most of the others are apparently non-variable, intracellular trypanosome proteins. Two of these antigens I2 and I17 are now characterized at the molecular level. Both exhibit a highly repetitive amino acid sequence organization, but they show no sequence similarity either to each other or to any other proteins known to date. Preliminary serological analyses indicate that both allow the early, sensitive and specific detection of infections with different species of trypanosomatids, making them interesting candidates for the development of diagnostic tools for trypanosomiasis detectio
Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens
Trypanosome infection of mammalian hosts leads, within days, to a strong early response against a small, distinct number of parasite proteins. One of these proteins is the variable surface glycoprotein (VSG). Most of the others are apparently non-variable, intracellular trypanosome proteins. Two of these antigens I2 and I17 are now characterized at the molecular level. Both exhibit a highly repetitive amino acid sequence organization, but they show no sequence similarity either to each other or to any other proteins known to date. Preliminary serological analyses indicate that both allow the early, sensitive and specific detection of infections with different species of trypanosomatids, making them interesting candidates for the development of diagnostic tools for trypanosomiasis detection
Cytoskeleton-associated antigens from African trypanosomes are recognized by self-reactive antibodies of uninfected mice
Serum from uninfected mice of different strains, as well as from germ-free animals, contains antibodies which react specifically with at least two trypanosomal proteins, I/6 and MARP1. These antibody populations are highly specific for the respective proteins, are of similar affinity as hyperimmune antibodies, and consist of IgM as well as IgG isotypes. Hyperimmune antibody raised against the cross-reacting trypanosomal protein I/6 detects a 60 kDa protein in mouse 3T6 cells, which is a component of the fibroblast cytoskeleto
Identification and characterization of two repetitive non-variable antigens from African trypanosomes which are recognized early during infection
The present paper describes two repetitive proteins representing common antigens of African trypanosomes which are non-variant and which are recognized early in infection by the host immune system. These antigens were identified by their ability to immunoreact with bovine serum taken during the early phase of a cyclic trypanosomal infection. Screening of a cDNA library from T. b. gambiense with such early infection serum identified a protein which contains a repetitive motif consisting of 68 amino acid repeat units (GM6). Immunofluorescence and immunogold electron microscopy revealed that GM6 is located on fibres which connect the microtubules of the membrane skeleton with the flagellum. A second repetitive antigen detected by this serum is MARP1 (microtubule-associated repetitive protein 1), a protein previously characterized in this laboratory as a high-molecular weight component of the membrane skeleton, which consists of more than 50 tandemly repeated, near-identical 38 amino acid repeat units. Beta-galactosidase fusion products of both proteins demonstrated a strong immunoreactivity with sera from T. b. brucei and T. congolense-infected cattle. The result from this preliminary immunological evaluation indicates a high immunodiagnostic sensititivy (90%) of the two recombinant antigens which make them interesting candidates for immunodiagnosis of trypanosomiasis in cattl
Identification and characterization of two repetitive non-variable antigens from African trypanosomes which are recognized early during infection
The present paper describes two repetitive proteins representing common antigens of African trypanosomes which are non-variant and which are recognized early in infection by the host immune system. These antigens were identified by their ability to immunoreact with bovine serum taken during the early phase of a cyclic trypanosomal infection. Screening of a cDNA library from T. b. gambiense with such early infection serum identified a protein which contains a repetitive motif consisting of 68 amino acid repeat units (GM6). Immunofluorescence and immunogold electron microscopy revealed that GM6 is located on fibres which connect the microtubules of the membrane skeleton with the flagellum. A second repetitive antigen detected by this serum is MARP1 (microtubule-associated repetitive protein 1), a protein previously characterized in this laboratory as a high-molecular weight component of the membrane skeleton, which consists of more than 50 tandemly repeated, near-identical 38 amino acid repeat units. Beta-galactosidase fusion products of both proteins demonstrated a strong immunoreactivity with sera from T. b. brucei and T. congolense-infected cattle. The result from this preliminary immunological evaluation indicates a high immunodiagnostic sensititivy (90%) of the two recombinant antigens which make them interesting candidates for immunodiagnosis of trypanosomiasis in cattle
Spin-dependent thermoelectric transport in HgTe/CdTe quantum wells
We analyze thermally induced spin and charge transport in HgTe/CdTe quantum
wells on the basis of the numerical non-equilibrium Green's function technique
in the linear response regime. In the topologically non-trivial regime, we find
a clear signature of the gap of the edge states due to their finite overlap
from opposite sample boundaries -- both in the charge Seebeck and spin Nernst
signal. We are able to fully understand the physical origin of the
thermoelectric transport signatures of edge and bulk states based on simple
analytical models. Interestingly, we derive that the spin Nernst signal is
related to the spin Hall conductance by a Mott-like relation which is exact to
all orders in the temperature difference between the warm and the cold
reservoir.Comment: 11 pages, 13 figures, submitted to PR
A four-point measurement probe for brain tissue conductivity and permittivity characterization
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